Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 57138
  • Symbol: Slc12a5
  • Description: solute carrier family 12, member 5
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
57138 Q91V14 S12A5_MOUSE Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (mKCC2) (Neuronal K-Cl cotransporter) DISRUPTION PHENOTYPE Death at birth due to severe motor deficits including respiratory failure. {ECO:0000269|PubMed:11395011}.; DISRUPTION PHENOTYPE: [Isoform 2]: Mice lacking isoform 2 die within 2 weeks after birth. {ECO:0000269|PubMed:17715129}.