Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 64930
  • Symbol: Tsc1
  • Description: TSC complex subunit 1
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Gene ID Entry Entry Name Protein Name Type Information
64930 Q9EP53 TSC1_MOUSE Hamartin (Tuberous sclerosis 1 protein homolog) DISRUPTION PHENOTYPE Conditional knockout in glia causes an increase in HSP90AA1 ATPase activity and a down-regulation of ULK1, ERBB2, ESR1 and NR3C1 protein levels in the brain. {ECO:0000269|PubMed:29127155}.