Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 66663
  • Symbol: Uba5
  • Description: ubiquitin-like modifier activating enzyme 5
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Gene ID Entry Entry Name Protein Name Type Information
66663 Q8VE47 UBA5_MOUSE Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) DISRUPTION PHENOTYPE Death at embryonic day 12.5 (PubMed:20018847, PubMed:21304510). Embryonic lethality is caused by severe anemia associated with defective differentiation of both megakaryocytes and erythrocytes from common myeloid progenitors (PubMed:21304510). {ECO:0000269|PubMed:20018847, ECO:0000269|PubMed:21304510}.