Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 67784
  • Symbol: Plxnd1
  • Description: plexin D1
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Gene ID Entry Entry Name Protein Name Type Information
67784 Q3UH93 PLXD1_MOUSE Plexin-D1 DISRUPTION PHENOTYPE Neonate lethality, due to defects in the development of the heart outflow tract and in aortic arch patterning, plus defects in peripheral vasculature. Mice also display skeletal defects, but these may be caused by defects in the embryonic vasculature. {ECO:0000269|PubMed:15239958, ECO:0000269|PubMed:18992737}.