Mine Disruption Phenotype

Gene Info

  • Species: Mouse (Mus musculus)
  • GeneID: 71279
  • Symbol: Slc29a3
  • Description: solute carrier family 29 (nucleoside transporters), member 3
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Gene ID Entry Entry Name Protein Name Type Information
71279 Q99P65 S29A3_MOUSE Equilibrative nucleoside transporter 3 (mENT3) (Solute carrier family 29 member 3) DISRUPTION PHENOTYPE Knockout mice show lysosomal nucleoside buildup, elevated intralysosomal pH, altered macrophage function, and develop spontaneous and progressive macrophage-dominated histiocytosis. {ECO:0000269|PubMed:22174130}.