Mine Disruption Phenotype

Gene Info

  • Species: Rat (Rattus norvegicus)
  • GeneID: 117287
  • Symbol: Park7
  • Description: Parkinsonism associated deglycase
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Gene ID Entry Entry Name Protein Name Type Information
117287 O88767 PARK7_RAT Parkinson disease protein 7 homolog (Contraception-associated protein 1) (Protein CAP1) (Fertility protein SP22) (Maillard deglycase) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, DISRUPTION PHENOTYPE Mutants rear and groom less, they have a shorter stride length than their wild-type counterparts, but take more forelimb and hindlimb steps. They display deficits in short-term spatial memory as early as 4.5 months of age during place preference testing, as well as impaired coping strategies in the forced swim test. {ECO:0000269|PubMed:31250274}.