Mine Disruption Phenotype

Gene Info

  • Species: Yeast (Saccharomyces cerevisiae)
  • GeneID: 851013
  • Symbol: ACO1
  • Description: aconitate hydratase ACO1
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Gene ID Entry Entry Name Protein Name Type Information
851013 P19414 ACON_YEAST Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) DISRUPTION PHENOTYPE Essential for growth on nonfermentable carbon sources and for biosynthesis of glutamate. Causes a dramatic increase in cellular citrate levels. {ECO:0000269|PubMed:10224250, ECO:0000269|PubMed:18359281, ECO:0000269|PubMed:1972545}.