| 851888 |
Q05567 |
SGPL_YEAST |
Sphingosine-1-phosphate lyase (S1PL) (SP-lyase) (ySPL) (EC 4.1.2.-) (EC 4.1.2.27) (Bestowed of sphingosine tolerance 1) (Sphingosine-1-phosphate aldolase) |
DISRUPTION PHENOTYPE |
Leads to the accumulation of endogenous phosphorylated sphingoid bases, and exhibits unregulated proliferation upon approach to stationary phase (PubMed:10329480). Causes a reduction in total C15 and C17 phosphatidylcholine levels (PubMed:25345524). {ECO:0000269|PubMed:10329480, ECO:0000269|PubMed:25345524}. |