Mine Disruption Phenotype

Gene Info

  • Species: Yeast (Saccharomyces cerevisiae)
  • GeneID: 855709
  • Symbol: RCM1
  • Description: rRNA (cytosine-C5-)-methyltransferase RCM1
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Gene ID Entry Entry Name Protein Name Type Information
855709 P53972 RCM1_YEAST 25S rRNA (cytosine(2278)-C(5))-methyltransferase (EC 2.1.1.311) (rRNA m(5)C methyltransferase 1) DISRUPTION PHENOTYPE Altered structural conformation of the ribosome in close proximity to cytosine 2278 (m5C2278) in 25S rRNA, leading to impaired translational fidelity, and promote recruitment of a distinct subset of oxidative stress-responsive mRNAs into polysomes. {ECO:0000269|PubMed:25635753}.