Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 172437
  • Symbol: plin-1
  • Description: Perilipin-1 homolog
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Gene ID Entry Entry Name Protein Name Type Information
172437 A8WHP8 PLIN1_CAEEL Perilipin-1 homolog (Lipid droplet-associated protein) DISRUPTION PHENOTYPE Viable, and able to reproduce normally, but embryos contain large lipid droplets (PubMed:26121959, PubMed:26357594). Reduced body fat accumulation (PubMed:26121959). Lipid droplets cluster in intestinal cells and contain a reduced amount of triglycerides (PubMed:26025681). RNAi-mediated knockdown results in a reduced brood size (PubMed:26357594). {ECO:0000269|PubMed:26025681, ECO:0000269|PubMed:26357594}.