Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 172655
  • Symbol: idha-1
  • Description: putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
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Gene ID Entry Entry Name Protein Name Type Information
172655 Q93714 IDH3A_CAEEL Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase subunit alpha) (NAD(+)-specific ICDH subunit alpha) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes accumulation of citrate, leading to induction of the citrate-induced mitochondrial unfolded protein response (mtUPR). {ECO:0000269|PubMed:35021096}.