Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 173319
  • Symbol: lev-11
  • Description: Tropomyosin isoforms a/b/d/f;Tropomyosin isoforms c/e;Uncharacterized protein
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Gene ID Entry Entry Name Protein Name Type Information
173319 Q22866 TPM1_CAEEL Tropomyosin isoforms a/b/d/f (Levamisole resistant protein 11) DISRUPTION PHENOTYPE Worms have 50-75% embryonic lethality (PubMed:15930100). Those that survive body wall interference have abnormal body morphology and uncoordinated movements, and those that survive pharynx interference have deformed pharynges and gut regions (PubMed:15930100). RNAi-mediated knockdown results in a wavy appearance of the actin filaments in adult body wall muscles (PubMed:17684058). {ECO:0000269|PubMed:15930100, ECO:0000269|PubMed:17684058}.
173319 Q27249 TPM3_CAEEL Tropomyosin isoforms c/e (Levamisole resistant protein 11) DISRUPTION PHENOTYPE Worms have 50-75% embryonic lethality. Those that survive body wall interference have abnormal body morphology and uncoordinated movements, and those that survive pharynx interference have deformed pharynges and gut regions. {ECO:0000269|PubMed:15930100}.