Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 174121
  • Symbol: egl-27
  • Description: Egg-laying defective protein 27;GATA-type domain-containing protein
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Gene ID Entry Entry Name Protein Name Type Information
174121 Q09228 EGL27_CAEEL Egg-laying defective protein 27 DISRUPTION PHENOTYPE Shortened lifespan and reduced survival in response to heat stress. Impaired differentiation of the Y rectal cell to the PDA neuron with the Y cell remaining undifferentiated in its original rectal location. Double RNAi-mediated knockdown with lin-40 results in delayed cell cycle progression in mesodermal and endodermal embryonic lineages, but accelerated cell cycle progression in a subset of embryonic lineages (PubMed:25446273). {ECO:0000269|PubMed:22493276, ECO:0000269|PubMed:23271974, ECO:0000269|PubMed:25446273}.