Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 175277
  • Symbol: exc-6
  • Description: Excretory canal abnormal protein 6
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Gene ID Entry Entry Name Protein Name Type Information
175277 Q9TYU9 EXC6_CAEEL Excretory canal abnormal protein 6 DISRUPTION PHENOTYPE Defective cytoskeleton organization characterized by disrupted F-actin and microtubule dynamics leading to abnormal excretory cell tubulogenesis. Specifically, F-actin structure and organization in excretory cell canals throughout life is disrupted and microtubule organizing centers accumulate at the tips of excretory cell canals, with a strong reduction along the canals, and the direction of microtubule growth is altered. {ECO:0000269|PubMed:25771894}.