Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 176121
  • Symbol: aco-2
  • Description: putative aconitate hydratase, mitochondrial
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Gene ID Entry Entry Name Protein Name Type Information
176121 P34455 ACON_CAEEL Probable aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes accumulation of citrate, leading to induction of the citrate-induced mitochondrial unfolded protein response (mtUPR). {ECO:0000269|PubMed:35021096}.