Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 176640
  • Symbol: php-3
  • Description: Homeobox protein php-3
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Gene ID Entry Entry Name Protein Name Type Information
176640 Q9XW88 PHP3_CAEEL Homeobox protein php-3 (Posterior Hox protein paralog 3) DISRUPTION PHENOTYPE RNAi-mediated knockdown in adults has no effect on their F1 progeny, but increases the frequency of posterior morphological abnormalities on a homeobox nob-1 mutant background (PubMed:10781051). However, RNAi-mediated knockdown in L1 larvae causes defects in tail tip morphogenesis, which are exacerbated on a nob-1 mutant background (PubMed:21408209). {ECO:0000269|PubMed:10781051, ECO:0000269|PubMed:21408209}.