Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 176857
  • Symbol: spl-1
  • Description: Sphingosine-1-phosphate lyase
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Gene ID Entry Entry Name Protein Name Type Information
176857 Q9Y194 SGPL_CAEEL Sphingosine-1-phosphate lyase (S1PL) (SP-lyase) (SPL) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase) DISRUPTION PHENOTYPE Without spl-1 expression, animals become bloated, pale, congested with eggs and hatched larvae, and demonstrate shrunken gut and gonadal structures. {ECO:0000269|PubMed:12682045}.