Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 179071
  • Symbol: spe-39
  • Description: Spermatogenesis-defective protein 39
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Gene ID Entry Entry Name Protein Name Type Information
179071 Q23288 SPE39_CAEEL Spermatogenesis-defective protein 39 (SPE-39) (VPS33B-interacting protein in polarity and apical restriction) DISRUPTION PHENOTYPE Mutants produce spermatocytes that complete meiosis but do not usually form functional. Show defective vesicular biogenesis during spermatogenesis with morphogenesis failure of the specialized Golgi-derived fibrous body-membranous organelle (FB-MO) complexes. Show disrupted processing of endocytosed proteins in oocytes and coelomocytes. {ECO:0000269|PubMed:14504223, ECO:0000269|PubMed:19109425}.