Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 179824
  • Symbol: mes-4
  • Description: Histone-lysine N-methyltransferase mes-4
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Gene ID Entry Entry Name Protein Name Type Information
179824 Q9NH52 MES4_CAEEL Histone-lysine N-methyltransferase mes-4 (EC 2.1.1.357) (Maternal-effect sterile protein 4) DISRUPTION PHENOTYPE Derepression of X-linked genes in the germline. RNAi-mediated knockdown results in sterility (PubMed:16710447). RNAi-mediated knockdown suppresses the multivulval phenotype of the lin-15A/B n765 mutant (PubMed:16507136, PubMed:16710447). RNAi-mediated knockdown at 25 degrees Celsius rescues the larval lethality phenotype of the mep-1 (q660) single mutants (PubMed:16710447). {ECO:0000269|PubMed:12077420, ECO:0000269|PubMed:16507136, ECO:0000269|PubMed:16710447, ECO:0000269|PubMed:16968818}.