Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 179972
  • Symbol: unc-112
  • Description: Protein unc-112
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
179972 Q18685 UN112_CAEEL Protein unc-112 (Mitogen-inducible mig-2 protein-like) (Uncoordinated protein 112) DISRUPTION PHENOTYPE RNAi-mediated knockdown results in impaired mobility, mitochondrial fragmentation and disrupted integrin attachment complexes in muscle. This leads to degradation of muscle proteins in the cytosol, myofibrillar defects and disruption of sarcomere organization. {ECO:0000269|PubMed:22253611}.