Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 180111
  • Symbol: cpl-1
  • Description: Cathepsin L-like
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Gene ID Entry Entry Name Protein Name Type Information
180111 O45734 CPL1_CAEEL Cathepsin L-like (EC 3.4.22.15) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes early embryonic lethality with embryos arrested at the 100-200 cell stage (PubMed:11707440). The few larvae which survive have incomplete gut development and die at the L1 stage (PubMed:11707440). RNAi-mediated knockdown at the L3 larval stage causes a growth delay, adults are shorter and thinner, and lay fewer eggs (PubMed:11707440). {ECO:0000269|PubMed:11707440}.