Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 180692
  • Symbol: vha-12
  • Description: V-type proton ATPase subunit B 1
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Gene ID Entry Entry Name Protein Name Type Information
180692 Q19626 VATB1_CAEEL V-type proton ATPase subunit B 1 (V-ATPase subunit B 1) (Vacuolar proton pump subunit B 1) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes hyperfusion of embryonic epidermal cells (PubMed:15866168). RNAi-mediated knockdown suppresses hypoxia-induced cell death, and, in a mec-4 (u231) mutant background, neurodegeneration of touch-receptor neurons (PubMed:16005300). {ECO:0000269|PubMed:15866168, ECO:0000269|PubMed:16005300}.