Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 180833
  • Symbol: egl-13
  • Description: HMG box domain-containing protein;Transcription factor egl-13
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Gene ID Entry Entry Name Protein Name Type Information
180833 Q23045 EGL13_CAEEL Transcription factor egl-13 (Protein egg laying defective 13) DISRUPTION PHENOTYPE Hermaphrodites have an egg laying defective phenotype and a reduced brood size (PubMed:9834196). They display a protruding vulva phenotype and there is a failure of anchor cells to fuse to uterine seam cells (anchor cell-block) (PubMed:9834196). Animals also have defective vulval morphogenesis and gonad migration with increased pi cell divisions, which thus leads to an improper uterine-vulval connection (PubMed:9834196, PubMed:14668410). Defective response to CO(2) sensing (PubMed:23671427). {ECO:0000269|PubMed:14668410, ECO:0000269|PubMed:23671427}.