Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 181444
  • Symbol: asp-4
  • Description: Aspartic protease 4
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Gene ID Entry Entry Name Protein Name Type Information
181444 Q21966 ASP4_CAEEL Aspartic protease 4 (EC 3.4.23.-) DISRUPTION PHENOTYPE RNAi-mediated knockdown prevents muscle degeneration caused by bacterium A.dhakensis-mediated infection (PubMed:28101079). RNAi-mediated knockdown prevents neuronal degeneration in a mec-4(u231), deg-1(u38) or gsa-1(Q227L) gain-of-function mutant background (PubMed:12410314). {ECO:0000269|PubMed:12410314, ECO:0000269|PubMed:28101079}.