Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 181580
  • Symbol: egrh-1
  • Description: Early growth response factor homolog 1
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Gene ID Entry Entry Name Protein Name Type Information
181580 Q18250 EGRH1_CAEEL Early growth response factor homolog 1 DISRUPTION PHENOTYPE RNAi-mediated knockdown causes abnormalities in oocyte development, including degrading oocytes in the proximal gonadal arm and ectopic developing oocytes in the distal arm (PubMed:20736289). RNAi-mediated knockdown targeted to the soma, on an rrf-1 mutant background, exhibits only a slight increase in the frequency of oocyte defects (PubMed:20736289). {ECO:0000269|PubMed:20736289}.