| 181620 |
Q20471 |
KIN20_CAEEL |
Casein kinase I isoform delta (EC 2.7.11.1) (Protein kinase 20) |
DISRUPTION PHENOTYPE |
RNAi-mediated knockdown results in precocious seam cell fusion and the early exit of seam cell from the cell cycle during the L4 larval stage (PubMed:15691769). RNAi-mediated knockdown does not impair alae formation (PubMed:15691769). RNAi-mediated knockdown results in a squat body statue, referred to as a dumpy phenotype, and rescues the incomplete alae formation defect in the lin-42 (n1089) mutant (PubMed:29880558). RNAi-mediated knockdown increases the survival rate and partially restores alae formation of let-7 n2853 mutants at 20 dgrees Celsius (PubMed:15691769). RNAi-mediated knockdown rescues the lethal bursting phenotype that occurs after the L4 stage molt in the let-7(n2853) mutant at 25 degrees Celsius (PubMed:29880558). {ECO:0000269|PubMed:15691769, ECO:0000269|PubMed:29880558}. |