Mine Disruption Phenotype

Gene Info

  • Species: Worm (Caenorhabditis elegans)
  • GeneID: 183539
  • Symbol: ref-2
  • Description: Zinc finger transcription factor ref-2
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Gene ID Entry Entry Name Protein Name Type Information
183539 Q7JNM3 ZICH2_CAEEL Zinc finger transcription factor ref-2 (Regulator of fusion 2) (Zic transcription factor ref-2) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes many hermaphrodite progeny to be vulval-less and so unable to lay eggs (PubMed:12091304). Few or none of the Pn.p cells remain unfused in hermaphrodites or males (PubMed:12091304). In some conditions, despite being present in their normal position at hatching, P cells fail to migrate into the ventral cord during the larval L1 stage (PubMed:12091304). {ECO:0000269|PubMed:12091304}.