Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 31118
  • Symbol: dor
  • Description: deep orange
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Gene ID Entry Entry Name Protein Name Type Information
31118 Q24314 VPS18_DROME Vacuolar protein sorting-associated protein 18 homolog (Protein deep orange) DISRUPTION PHENOTYPE Flies display impaired deposition of pigment granules (PubMed:9065698, PubMed:10549280). Member of the 'granule group' of eye color genes as mutants affect deposition in pigment granules of two types of pigments, the ommochromes and drosopterins (PubMed:9065698, PubMed:10549280). RNAi-mediated knockdown results in late endosome fragmentation and mislocalization of Vps8 (PubMed:27253064). {ECO:0000269|PubMed:10549280, ECO:0000269|PubMed:27253064, ECO:0000269|PubMed:9065698}.