| 31547 |
Q9W436 |
NEP_DROME |
Neprilysin-1 (EC 3.4.24.11) |
DISRUPTION PHENOTYPE |
RNAi-mediated knockdown females lay fewer eggs and display a reduced hatch rate when mated to wild-type males, and wild-type females lay fewer eggs when mated to RNAi-mediated knockdown males (PubMed:24395329). RNAi-mediated knockdown in the dorsal paired medial neurons impairs middle-term (MTM) and long-term memory (LTM), but has no effect on normal aversion learning and anesthesia-resistant memory (ARM) (PubMed:27629706). RNAi-mediated knockdown in alpha/beta mushroom body neurons impairs MTM and LTM (PubMed:27629706). RNAi-mediated knockdown in all mushroom body neurons has no effect on learning and ARM (PubMed:27629706). {ECO:0000269|PubMed:24395329, ECO:0000269|PubMed:27629706}. |