Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 319033
  • Symbol: Rrp40
  • Description: Ribosomal RNA processing 40
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Gene ID Entry Entry Name Protein Name Type Information
319033 Q8IPX7 EXOS3_DROME Exosome complex component RRP40 (Ribosomal RNA-processing protein 40) DISRUPTION PHENOTYPE RNAi-mediated knockdown in the whole body, neurons, glia or muscles is lethal (PubMed:32645003). RNAi-mediated knockdown in mushroom bodies affects the morphology of the alpha- and beta-lobes as well as ellipsoid bodies (PubMed:32645003). RNAi-mediated knockdown in the wing pouch results in severe wing development phenotypes and increase of miR-252-5p expression (PubMed:25892215). {ECO:0000269|PubMed:25892215, ECO:0000269|PubMed:32645003}.