Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 32094
  • Symbol: Uba5
  • Description: Ubiquitin-like activating enzyme 5
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Gene ID Entry Entry Name Protein Name Type Information
32094 Q9VYY3 UBA5_DROME Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) DISRUPTION PHENOTYPE RNAi-mediated knockdown shows aberrant neuromuscular junctions in the larval muscle and abnormal wings, locomotive defects and a shortened lifespan in the adult fly. RNAi-mediated knockdown in the nervous system results also in aberrant neuromuscular junctions characterized by reduced number of type Ib boutons and increased bouton size in the larval muscle. {ECO:0000269|PubMed:26872069}.