Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 326245
  • Symbol: Gorab
  • Description: Golgin, RAB6 interacting
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Gene ID Entry Entry Name Protein Name Type Information
326245 Q8IQQ4 GORAB_DROME RAB6-interacting golgin DISRUPTION PHENOTYPE Viable (PubMed:29892014). Loss of daughter centrioles and asymmetrical mother centriole-derived basal body results in defective nine-fold symmetry of cilia in neurosensory organs and therefore motor coordination defects (PubMed:29892014, PubMed:33704067). Plp-associated structures are also disorganized but ciliary structures are still present in the scolopale rods (PubMed:29892014). Males are fertile, whereas female are sterile (PubMed:29892014). Results in failure to duplicate centrosomes in embryos and diploid larval tissues (PubMed:29892014). {ECO:0000269|PubMed:29892014, ECO:0000269|PubMed:33704067}.