| 33401 |
Q9VQ91 |
TDRKH_DROME |
Tudor and KH domain-containing protein homolog (Partner of PIWIs protein) |
DISRUPTION PHENOTYPE |
RNAi-mediated knockdown does not produce a visible phenotype. However, fertility is reduced with egg-laying decreased by 30%. AGO3 protein levels are decreased and AGO3 is delocalized from the nuage. No effect on nuage morphology and no mislocalization of piwi and aub. RNAi-mediated knockdown in germline tissues results in delocalization of AGO3 from the nuage. {ECO:0000269|PubMed:21447556}. |