| 34481 |
Q9V466 |
NU107_DROME |
Nuclear pore complex protein Nup107 (Nucleoporin Nup107) |
DISRUPTION PHENOTYPE |
Embryonic lethal (PubMed:18562695, PubMed:26485283). RNAi-mediated knockdown in somatic gonadal cells results in female, but not male, infertility associated with extensive disintegration of the egg chambers and cell death in nurse cells (PubMed:26485283). RNAi-mediated knockdown in spermatocytes causes abnormal localization of nuclear type-B lamin Lam, abnormal spindle envelope integrity and overall defective cytokinesis in meiosis (PubMed:27402967). {ECO:0000269|PubMed:18562695, ECO:0000269|PubMed:26485283, ECO:0000269|PubMed:27402967}. |