| 35713 |
Q9V4Q8 |
RU2A_DROME |
Probable U2 small nuclear ribonucleoprotein A' (U2 snRNP A') |
DISRUPTION PHENOTYPE |
Embryonic lethal (PubMed:27035939). RNAi-mediated knockdown in male germ cells, spermatogonia and surrounding somatic cells results in increased spermatogonia proliferation, failure to complete developmental programs of meiosis and differentiation and ultimately leads to complete male sterility (PubMed:27035939). RNAi-mediated knockdown in female germline results in defective oogenesis (PubMed:24244416). {ECO:0000269|PubMed:24244416, ECO:0000269|PubMed:27035939}. |