Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 36699
  • Symbol: Arf6
  • Description: ADP ribosylation factor 6
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Gene ID Entry Entry Name Protein Name Type Information
36699 P40946 ARF6_DROME ADP-ribosylation factor 6 (ARF6) (ADP ribosylation factor at 51F) (ADP-ribosylation factor 3) DISRUPTION PHENOTYPE Results in enhances preference and sensitivity to alcohol (PubMed:28607459). Fails to develop tolerance to repeated ethanol exposures (PubMed:28607459). Conditional RNAi-mediated knockdown in the eye results in aberrant compound eye morphogenesis, with defective cell intercalation patterns associated with altered actin dynamics (PubMed:21976699). {ECO:0000269|PubMed:21976699, ECO:0000269|PubMed:28607459}.