| 38447 |
Q94522 |
SUCA_DROME |
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) (Succinyl-coenzyme A synthetase alpha subunit 1) |
DISRUPTION PHENOTYPE |
Viable (PubMed:28017724). During development, results in delayed egg eclosion, reduced glycogen levels and extension of the third instar larval period but without change of the duration of the pupal period or final size of organ (PubMed:28017724). In the adult, results in defects in locomotor activity (PubMed:28017724). Results in disregulation of both glycolysis and the citric acid cycle (TCA) including accumulation of Succinyl-CoA and succinate, and reduction of GABA (PubMed:28017724). {ECO:0000269|PubMed:28017724}. |