Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 41709
  • Symbol: foxo
  • Description: forkhead box, sub-group O
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Gene ID Entry Entry Name Protein Name Type Information
41709 Q95V55 FOXO_DROME Forkhead box protein O (dFOXO) (Protein FKHR) DISRUPTION PHENOTYPE Mutant foxo lacking Akt1 phosphorylation sites no longer responds to insulin inhibition, remains in the nucleus, and is constitutively active, inducing cell arrest. {ECO:0000269|PubMed:12893776}.