Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 41839
  • Symbol: tefu
  • Description: telomere fusion
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Gene ID Entry Entry Name Protein Name Type Information
41839 Q5EAK6 ATM_DROME Serine/threonine-protein kinase ATM (EC 2.7.11.1) (Telomere fusion protein) DISRUPTION PHENOTYPE Flies die shortly before or after eclosion with a rough eye phenotype, misshapen wings, and missing or abnormal bristles (PubMed:15256487). Shows increased numbers of spontaneous tumors (PubMed:15256487). Simultaneous knockout of tefu and Clbn/NEMF increases the formation of spontaneous tumors (PubMed:22964637). {ECO:0000269|PubMed:15256487, ECO:0000269|PubMed:22964637}.