Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 42256
  • Symbol: Epg5
  • Description: ectopic P-granules autophagy protein 5
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Gene ID Entry Entry Name Protein Name Type Information
42256 Q9VE34 EPG5_DROME Ectopic P granules protein 5 homolog DISRUPTION PHENOTYPE Conditional CG14299 knockdown in fly larval fat bodies causes defects in the late steps of autophagy and a block in digestion of autolysosomes. Conditional down-regulation in adult fly retina reveals an incremental loss of neurons and of retina structure over time. {ECO:0000269|PubMed:26917586}.