Mine Disruption Phenotype

Gene Info

  • Species: Fly (Drosophila melanogaster)
  • GeneID: 46059
  • Symbol: Sply
  • Description: Sphingosine-1-phosphate lyase
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Gene ID Entry Entry Name Protein Name Type Information
46059 Q9V7Y2 SGPL_DROME Sphingosine-1-phosphate lyase (S1PL) (SP-lyase) (SPL) (EC 4.1.2.27) (Sphingosine-1-phosphate aldolase) DISRUPTION PHENOTYPE Flies lacking Sply display decreased viability associated with altered nephrocytes morphology. Altered lipid metabolism with accumulation of sphingosine-1-phosphate upstream intermediates is observed. {ECO:0000269|PubMed:28165339}.