Mine Disruption Phenotype

Gene Info

  • Species: Zebrafish (Danio rerio)
  • GeneID: 100005174
  • Symbol: dnmbp
  • Description: dynamin binding protein
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Gene ID Entry Entry Name Protein Name Type Information
100005174 E7F1U2 DNMBP_DANRE Dynamin-binding protein (Scaffold protein Tuba) DISRUPTION PHENOTYPE The morphants contained multiple phenotypic defects, beginning with a downward-curled tail at 2 dpf. Additional ciliary defects after 3 dpf included small eyes, pericardial edema and hydrocephalus. These defects became more severe, leading to abdominal fluid accumulation, as well as abnormal pronephric kidneys at 5 dpf. {ECO:0000269|PubMed:26895965}.