Mine Disruption Phenotype

Gene Info

  • Species: Zebrafish (Danio rerio)
  • GeneID: 30432
  • Symbol: smn1
  • Description: survival of motor neuron 1, telomeric
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Gene ID Entry Entry Name Protein Name Type Information
30432 Q9W6S8 SMN1_DANRE Survival motor neuron protein 1 DISRUPTION PHENOTYPE Decreased axonal branches and decreased dendrites in motor neurons (PubMed:29061699). Decreased GAP43 mRNA levels (PubMed:29061699). Morpholino knockdown of the protein causes severe defects in motor neuron axonal outgrowth, including truncations and abnormal branching (PubMed:23063131). {ECO:0000269|PubMed:23063131, ECO:0000269|PubMed:29061699}.