Mine Disruption Phenotype

Gene Info

  • Species: Zebrafish (Danio rerio)
  • GeneID: 450008
  • Symbol: trappc6b
  • Description: trafficking protein particle complex subunit 6B
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Gene ID Entry Entry Name Protein Name Type Information
450008 F1QMV3 TPC6B_DANRE Trafficking protein particle complex subunit 6b (TRAPP complex subunit 6B) DISRUPTION PHENOTYPE Morpholino knockdown of the protein causes neurodevelopmental abnormalities associated with decreased survival rate. Morphants are characterized by microcephaly, brain hyperexcitability and lower seizure threshold. {ECO:0000269|PubMed:28626029}.