Mine Disruption Phenotype

Gene Info

  • Species: Zebrafish (Danio rerio)
  • GeneID: 563878
  • Symbol: pomt2
  • Description: protein-O-mannosyltransferase 2
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Gene ID Entry Entry Name Protein Name Type Information
563878 F1Q8R9 POMT2_DANRE Protein O-mannosyl-transferase 2 (EC 2.4.1.109) DISRUPTION PHENOTYPE Morpholino knockdown of the protein results in developmental delays at 18 hours post fertilization (hpf). At 48-72 hpf the tail is abnormally twisted, and pericardium formation and eye pigmentation are also abnormal. Swim bladders are incompletely formed. Glycosylation of alpha-dystroglycan (dag1) is severely reduced. {ECO:0000269|PubMed:20466645}.