Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 93
• Symbol: ACVR2B
• Description: activin A receptor type 2B

DataSource: http://genomecrispr.dkfz.de/#!/results/ACVR2B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38477890	38477913	3	-	26472758	Jiyoye	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.6130115614604259	[312]	[360]	4	hSpCas9	negative selection	2331
38478390	38478413	3	-	26472758	Jiyoye	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	1.1804045196588513	[54]	[93]	7	hSpCas9	negative selection	2332
38479120	38479143	3	+	26472758	Jiyoye	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.5261461934673128	[348]	[378]	4	hSpCas9	negative selection	2333
38454343	38454366	3	-	26472758	Jiyoye	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	1.2961440691171293	[26]	[49]	7	hSpCas9	negative selection	2334
38477293	38477316	3	+	26472758	Jiyoye	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-5.742571737998809	[70]	[0]	-9	hSpCas9	negative selection	2335
38477372	38477395	3	+	26472758	Jiyoye	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	-0.1907261749227811	[55]	[36]	-1	hSpCas9	negative selection	2336
38478168	38478191	3	-	26472758	Jiyoye	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	1.285184857127263	[36]	[67]	7	hSpCas9	negative selection	2337
38478220	38478243	3	-	26472758	Jiyoye	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	5.992137882227029	[0]	[47]	9	hSpCas9	negative selection	2338
38478267	38478290	3	-	26472758	Jiyoye	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-1.177787119215283	[464]	[154]	-7	hSpCas9	negative selection	2339
38478377	38478400	3	-	26472758	Jiyoye	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.9823914302568522	[130]	[24]	-8	hSpCas9	negative selection	2340
38477890	38477913	3	-	26472758	KBM7	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.5570323869636955	[1771,1180]	[1336,708]	6	hSpCas9	negative selection	193449
38478390	38478413	3	-	26472758	KBM7	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.2861278759107645	[592,514]	[257,172]	-3	hSpCas9	negative selection	193450
38479120	38479143	3	+	26472758	KBM7	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	-0.03183290919717541	[1416,1022]	[590,521]	0	hSpCas9	negative selection	193451
38454343	38454366	3	-	26472758	KBM7	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.06042221486098054	[187,239]	[113,83]	0	hSpCas9	negative selection	193452
38477293	38477316	3	+	26472758	KBM7	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-1.7970891866362555	[189,106]	[7,29]	-8	hSpCas9	negative selection	193453
38477372	38477395	3	+	26472758	KBM7	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.6322661850795951	[225,107]	[81,149]	7	hSpCas9	negative selection	193454
38478168	38478191	3	-	26472758	KBM7	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	-0.004260101529335314	[249,194]	[112,94]	0	hSpCas9	negative selection	193455
38478220	38478243	3	-	26472758	KBM7	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-0.6604233151044392	[177,207]	[26,85]	-5	hSpCas9	negative selection	193456
38478267	38478290	3	-	26472758	KBM7	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.44731758154848533	[1226,1233]	[727,850]	5	hSpCas9	negative selection	193457
38478377	38478400	3	-	26472758	KBM7	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-0.9410514431078056	[653,374]	[101,141]	-6	hSpCas9	negative selection	193458
38477890	38477913	3	-	26472758	Raji	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.051414723228372594	[656]	[157]	0	hSpCas9	negative selection	384567
38478390	38478413	3	-	26472758	Raji	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.4732005248369823	[328]	[54]	-4	hSpCas9	negative selection	384568
38479120	38479143	3	+	26472758	Raji	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	-0.13899352650658614	[464]	[97]	-1	hSpCas9	negative selection	384569
38454343	38454366	3	-	26472758	Raji	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	1.014274130982118	[63]	[29]	8	hSpCas9	negative selection	384570
38477293	38477316	3	+	26472758	Raji	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.062541466068713	[71]	[0]	-9	hSpCas9	negative selection	384571
38477372	38477395	3	+	26472758	Raji	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	-0.7170449000429462	[84]	[11]	-5	hSpCas9	negative selection	384572
38478168	38478191	3	-	26472758	Raji	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.5726067918206601	[112]	[38]	5	hSpCas9	negative selection	384573
38478220	38478243	3	-	26472758	Raji	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	0.1439094113987136	[77]	[19]	1	hSpCas9	negative selection	384574
38478267	38478290	3	-	26472758	Raji	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.3066627615021944	[484]	[90]	-3	hSpCas9	negative selection	384575
38478377	38478400	3	-	26472758	Raji	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.3706637614310446	[233]	[20]	-7	hSpCas9	negative selection	384576
38477890	38477913	3	-	26472758	K562	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.022026306329999024	[1098]	[941]	0	hSpCas9	negative selection	575685
38478390	38478413	3	-	26472758	K562	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.5131571461750454	[469]	[277]	-3	hSpCas9	negative selection	575686
38479120	38479143	3	+	26472758	K562	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.9816636161982313	[1032]	[1721]	8	hSpCas9	negative selection	575687
38454343	38454366	3	-	26472758	K562	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	1.0863538814341953	[158]	[284]	8	hSpCas9	negative selection	575688
38477293	38477316	3	+	26472758	K562	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-5.37029111644876	[48]	[0]	-9	hSpCas9	negative selection	575689
38477372	38477395	3	+	26472758	K562	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	-1.305778354894033	[122]	[41]	-6	hSpCas9	negative selection	575690
38478168	38478191	3	-	26472758	K562	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.5644090183123166	[148]	[185]	4	hSpCas9	negative selection	575691
38478220	38478243	3	-	26472758	K562	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-0.9061409489089343	[110]	[49]	-5	hSpCas9	negative selection	575692
38478267	38478290	3	-	26472758	K562	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.20332653407170775	[640]	[622]	1	hSpCas9	negative selection	575693
38478377	38478400	3	-	26472758	K562	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-2.2198622906322463	[297]	[53]	-7	hSpCas9	negative selection	575694
38477419	38477442	3	-	26627737	DLD1	viability	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	1.584469555595988	[63]	[98,23,55]	9	hSpCas9	negative selection	821538
38477891	38477914	3	-	26627737	DLD1	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.14532242564085418	[794]	[296,114,387]	1	hSpCas9	negative selection	821539
38478237	38478260	3	-	26627737	DLD1	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.6279670298616473	[13]	[2,7,8]	6	hSpCas9	negative selection	821540
38479250	38479273	3	+	26627737	DLD1	viability	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.240097901068983	[832]	[240,271,159]	-3	hSpCas9	negative selection	821541
38479791	38479814	3	-	26627737	DLD1	viability	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.6163817962547369	[622]	[164,160,65]	-6	hSpCas9	negative selection	821542
38481415	38481438	3	+	26627737	DLD1	viability	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.792704625052189	[615]	[420,377,220]	7	hSpCas9	negative selection	821543
38477419	38477442	3	-	26627737	GBM cells	viability after 5 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	1.2564658795037693	[31]	[49,31]	9	hSpCas9	negative selection	903853
38477891	38477914	3	-	26627737	GBM cells	viability after 5 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.5716433583236576	[371]	[289,302]	8	hSpCas9	negative selection	903854
38478237	38478260	3	-	26627737	GBM cells	viability after 5 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.7531628216940076	[10]	[4,1]	-8	hSpCas9	negative selection	903855
38479250	38479273	3	+	26627737	GBM cells	viability after 5 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.01080765782270321	[541]	[297,278]	0	hSpCas9	negative selection	903856
38479791	38479814	3	-	26627737	GBM cells	viability after 5 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.5299883004611541	[194]	[155,145]	7	hSpCas9	negative selection	903857
38481415	38481438	3	+	26627737	GBM cells	viability after 5 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.122539896161244	[333]	[191,197]	2	hSpCas9	negative selection	903858
38477419	38477442	3	-	26627737	GBM cells	viability after 13 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	1.2250928339936398	[31]	[44,36]	9	hSpCas9	negative selection	986168
38477891	38477914	3	-	26627737	GBM cells	viability after 13 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6185211014765909	[371]	[278,334]	7	hSpCas9	negative selection	986169
38478237	38478260	3	-	26627737	GBM cells	viability after 13 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.28541296923792725	[10]	[5,3]	-3	hSpCas9	negative selection	986170
38479250	38479273	3	+	26627737	GBM cells	viability after 13 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.2529220296552144	[541]	[377,327]	3	hSpCas9	negative selection	986171
38479791	38479814	3	-	26627737	GBM cells	viability after 13 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.22099106279218797	[194]	[135,112]	3	hSpCas9	negative selection	986172
38481415	38481438	3	+	26627737	GBM cells	viability after 13 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.31660503749943586	[333]	[228,222]	4	hSpCas9	negative selection	986173
38477419	38477442	3	-	26627737	GBM cells	viability after 21 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.5137936737692987	[31]	[28,20]	5	hSpCas9	negative selection	1068483
38477891	38477914	3	-	26627737	GBM cells	viability after 21 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6678534959488812	[371]	[330,311]	6	hSpCas9	negative selection	1068484
38478237	38478260	3	-	26627737	GBM cells	viability after 21 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.27015151543100924	[10]	[5,3]	-2	hSpCas9	negative selection	1068485
38479250	38479273	3	+	26627737	GBM cells	viability after 21 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.41128027791091615	[541]	[412,371]	4	hSpCas9	negative selection	1068486
38479791	38479814	3	-	26627737	GBM cells	viability after 21 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	1.0192306832359452	[194]	[232,197]	8	hSpCas9	negative selection	1068487
38481415	38481438	3	+	26627737	GBM cells	viability after 21 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.6465583163862372	[333]	[317,252]	6	hSpCas9	negative selection	1068488
38477419	38477442	3	-	26627737	RPE1	viability after 9 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	9.120490528899403	[0]	[206,131]	9	hSpCas9	negative selection	1150798
38477891	38477914	3	-	26627737	RPE1	viability after 9 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.2389319183838018	[1341]	[331,386]	-2	hSpCas9	negative selection	1150799
38478237	38478260	3	-	26627737	RPE1	viability after 9 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.8397161147114955	[31]	[13,22]	5	hSpCas9	negative selection	1150800
38479250	38479273	3	+	26627737	RPE1	viability after 9 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.4577645465027572	[1902]	[297,608]	-3	hSpCas9	negative selection	1150801
38479791	38479814	3	-	26627737	RPE1	viability after 9 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-1.3267665448117614	[973]	[121,120]	-7	hSpCas9	negative selection	1150802
38481415	38481438	3	+	26627737	RPE1	viability after 9 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.2403050032677883	[991]	[617,882]	7	hSpCas9	negative selection	1150803
38477419	38477442	3	-	26627737	RPE1	viability after 12 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	9.061161954400001	[0]	[177,106]	9	hSpCas9	negative selection	1233113
38477891	38477914	3	-	26627737	RPE1	viability after 12 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6296204749216722	[1341]	[534,581]	4	hSpCas9	negative selection	1233114
38478237	38478260	3	-	26627737	RPE1	viability after 12 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.1698404183031683	[31]	[13,24]	7	hSpCas9	negative selection	1233115
38479250	38479273	3	+	26627737	RPE1	viability after 12 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.4981025475176789	[1902]	[242,487]	-3	hSpCas9	negative selection	1233116
38479791	38479814	3	-	26627737	RPE1	viability after 12 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-1.093515206597649	[973]	[109,135]	-6	hSpCas9	negative selection	1233117
38481415	38481438	3	+	26627737	RPE1	viability after 12 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.0179671656170284	[991]	[580,495]	6	hSpCas9	negative selection	1233118
38477419	38477442	3	-	26627737	RPE1	viability after 15 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	8.90329557253939	[0]	[222,50]	9	hSpCas9	negative selection	1315428
38477891	38477914	3	-	26627737	RPE1	viability after 15 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.215852049200699	[1341]	[418,461]	1	hSpCas9	negative selection	1315429
38478237	38478260	3	-	26627737	RPE1	viability after 15 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.7801506821817683	[31]	[12,17]	5	hSpCas9	negative selection	1315430
38479250	38479273	3	+	26627737	RPE1	viability after 15 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.9646145833497528	[1902]	[115,429]	-6	hSpCas9	negative selection	1315431
38479791	38479814	3	-	26627737	RPE1	viability after 15 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-1.6864596921973884	[973]	[107,63]	-8	hSpCas9	negative selection	1315432
38481415	38481438	3	+	26627737	RPE1	viability after 15 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.121795632527791	[991]	[769,456]	6	hSpCas9	negative selection	1315433
38477419	38477442	3	-	26627737	RPE1	viability after 18 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	9.264707691447667	[0]	[267,56]	9	hSpCas9	negative selection	1397743
38477891	38477914	3	-	26627737	RPE1	viability after 18 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.7693793428384111	[1341]	[684,544]	5	hSpCas9	negative selection	1397744
38478237	38478260	3	-	26627737	RPE1	viability after 18 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.7837388852371605	[31]	[10,18]	5	hSpCas9	negative selection	1397745
38479250	38479273	3	+	26627737	RPE1	viability after 18 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.36969234715726507	[1902]	[279,522]	-2	hSpCas9	negative selection	1397746
38479791	38479814	3	-	26627737	RPE1	viability after 18 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-1.3282337181007158	[973]	[109,98]	-7	hSpCas9	negative selection	1397747
38481415	38481438	3	+	26627737	RPE1	viability after 18 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.2148459796431093	[991]	[632,608]	7	hSpCas9	negative selection	1397748
38477419	38477442	3	-	26627737	HeLa	viability after 8 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	-0.3086874379180198	[124]	[63,10,59]	-3	hSpCas9	negative selection	1480058
38477891	38477914	3	-	26627737	HeLa	viability after 8 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.8875612794330839	[346]	[257,305,269]	7	hSpCas9	negative selection	1480059
38478237	38478260	3	-	26627737	HeLa	viability after 8 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.5374122874310938	[4]	[10,2,5]	9	hSpCas9	negative selection	1480060
38479250	38479273	3	+	26627737	HeLa	viability after 8 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.7902555677340847	[420]	[441,426,122]	6	hSpCas9	negative selection	1480061
38479791	38479814	3	-	26627737	HeLa	viability after 8 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.5357728962708347	[289]	[203,56,29]	-5	hSpCas9	negative selection	1480062
38481415	38481438	3	+	26627737	HeLa	viability after 8 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.5656619009099741	[432]	[493,945,241]	9	hSpCas9	negative selection	1480063
38477419	38477442	3	-	26627737	HeLa	viability after 12 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.41031150408998984	[124]	[0,77,123]	3	hSpCas9	negative selection	1562373
38477891	38477914	3	-	26627737	HeLa	viability after 12 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6065345232387692	[346]	[262,296,87]	5	hSpCas9	negative selection	1562374
38478237	38478260	3	-	26627737	HeLa	viability after 12 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	2.8476933312136885	[4]	[20,12,10]	9	hSpCas9	negative selection	1562375
38479250	38479273	3	+	26627737	HeLa	viability after 12 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.6719831524915257	[420]	[231,279,317]	5	hSpCas9	negative selection	1562376
38479791	38479814	3	-	26627737	HeLa	viability after 12 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.31608149311692324	[289]	[100,123,60]	-3	hSpCas9	negative selection	1562377
38481415	38481438	3	+	26627737	HeLa	viability after 12 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.702766244458378	[432]	[324,184,375]	5	hSpCas9	negative selection	1562378
38477419	38477442	3	-	26627737	HeLa	viability after 15 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.2331326121628412	[124]	[0,157,17]	2	hSpCas9	negative selection	1644688
38477891	38477914	3	-	26627737	HeLa	viability after 15 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6550203975500157	[346]	[258,243,158]	5	hSpCas9	negative selection	1644689
38478237	38478260	3	-	26627737	HeLa	viability after 15 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.7184808365700768	[4]	[9,3,5]	9	hSpCas9	negative selection	1644690
38479250	38479273	3	+	26627737	HeLa	viability after 15 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.9499943904772667	[420]	[271,415,303]	7	hSpCas9	negative selection	1644691
38479791	38479814	3	-	26627737	HeLa	viability after 15 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.25095246694293544	[289]	[164,189,59]	2	hSpCas9	negative selection	1644692
38481415	38481438	3	+	26627737	HeLa	viability after 15 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.7607014865293964	[432]	[156,427,313]	6	hSpCas9	negative selection	1644693
38477419	38477442	3	-	26627737	HeLa	viability after 18 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.26824812443721857	[124]	[0,133,17]	2	hSpCas9	negative selection	1727003
38477891	38477914	3	-	26627737	HeLa	viability after 18 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6963962573898317	[346]	[179,209,158]	5	hSpCas9	negative selection	1727004
38478237	38478260	3	-	26627737	HeLa	viability after 18 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.8086785725488266	[4]	[6,3,5]	9	hSpCas9	negative selection	1727005
38479250	38479273	3	+	26627737	HeLa	viability after 18 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.9502853326093104	[420]	[186,338,303]	7	hSpCas9	negative selection	1727006
38479791	38479814	3	-	26627737	HeLa	viability after 18 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.18191265000012857	[289]	[106,145,59]	1	hSpCas9	negative selection	1727007
38481415	38481438	3	+	26627737	HeLa	viability after 18 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.7934596767935835	[432]	[114,358,313]	6	hSpCas9	negative selection	1727008
38477419	38477442	3	-	26627737	HCT116	viability after 6 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	3.3869529210586427	[0]	[0,1]	9	hSpCas9	negative selection	1809318
38477891	38477914	3	-	26627737	HCT116	viability after 6 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	1.6520352723532856	[588]	[669,81]	8	hSpCas9	negative selection	1809319
38478237	38478260	3	-	26627737	HCT116	viability after 6 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-1.031179460953525	[12]	[0,0]	-5	hSpCas9	negative selection	1809320
38479250	38479273	3	+	26627737	HCT116	viability after 6 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.4372491036297179	[1471]	[342,75]	-2	hSpCas9	negative selection	1809321
38479791	38479814	3	-	26627737	HCT116	viability after 6 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	3.6240040479432047	[432]	[88,1252]	9	hSpCas9	negative selection	1809322
38481415	38481438	3	+	26627737	HCT116	viability after 6 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.3012104667769164	[633]	[525,90]	7	hSpCas9	negative selection	1809323
38477419	38477442	3	-	26627737	HCT116	viability after 8 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	1.1694725548438165	[26]	[28,11,58]	8	hSpCas9	negative selection	1891633
38477891	38477914	3	-	26627737	HCT116	viability after 8 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.274902406111573	[492]	[325,331,327]	3	hSpCas9	negative selection	1891634
38478237	38478260	3	-	26627737	HCT116	viability after 8 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	2.5307009403105876	[3]	[5,11,19]	9	hSpCas9	negative selection	1891635
38479250	38479273	3	+	26627737	HCT116	viability after 8 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.6197997009876678	[862]	[326,399,202]	-6	hSpCas9	negative selection	1891636
38479791	38479814	3	-	26627737	HCT116	viability after 8 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.9185623120652266	[274]	[124,93,22]	-8	hSpCas9	negative selection	1891637
38481415	38481438	3	+	26627737	HCT116	viability after 8 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	-0.006984986812406779	[528]	[272,310,285]	0	hSpCas9	negative selection	1891638
38477419	38477442	3	-	26627737	HCT116	viability after 9 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	6.6837477296898475	[0]	[46,11]	9	hSpCas9	negative selection	1973948
38477891	38477914	3	-	26627737	HCT116	viability after 9 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.7909113248333784	[588]	[129,59]	-5	hSpCas9	negative selection	1973949
38478237	38478260	3	-	26627737	HCT116	viability after 9 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	2.5567029026030563	[12]	[44,0]	9	hSpCas9	negative selection	1973950
38479250	38479273	3	+	26627737	HCT116	viability after 9 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.5337126976030373	[1471]	[692,470]	4	hSpCas9	negative selection	1973951
38479791	38479814	3	-	26627737	HCT116	viability after 9 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.027977034212034846	[432]	[118,116]	0	hSpCas9	negative selection	1973952
38481415	38481438	3	+	26627737	HCT116	viability after 9 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.4789633541019138	[633]	[183,276]	3	hSpCas9	negative selection	1973953
38477419	38477442	3	-	26627737	HCT116	viability after 12 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	2.1581044232388367	[26]	[58,47,82]	9	hSpCas9	negative selection	2056263
38477891	38477914	3	-	26627737	HCT116	viability after 12 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.17911548589212145	[492]	[148,289,255]	-2	hSpCas9	negative selection	2056264
38478237	38478260	3	-	26627737	HCT116	viability after 12 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.5734576147964914	[3]	[2,3,11]	9	hSpCas9	negative selection	2056265
38479250	38479273	3	+	26627737	HCT116	viability after 12 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.18735973321356192	[862]	[413,294,481]	-2	hSpCas9	negative selection	2056266
38479791	38479814	3	-	26627737	HCT116	viability after 12 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.23023900408251935	[274]	[94,160,116]	-2	hSpCas9	negative selection	2056267
38481415	38481438	3	+	26627737	HCT116	viability after 12 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.165978904041029	[528]	[277,283,375]	1	hSpCas9	negative selection	2056268
38477419	38477442	3	-	26627737	HCT116	viability after 15 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.8889047575282825	[26]	[32,52,0]	7	hSpCas9	negative selection	2138578
38477891	38477914	3	-	26627737	HCT116	viability after 15 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.1566558575683864	[492]	[300,408,235]	1	hSpCas9	negative selection	2138579
38478237	38478260	3	-	26627737	HCT116	viability after 15 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.7848716142260042	[3]	[9,5,7]	9	hSpCas9	negative selection	2138580
38479250	38479273	3	+	26627737	HCT116	viability after 15 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.7958994346586558	[862]	[270,327,255]	-7	hSpCas9	negative selection	2138581
38479791	38479814	3	-	26627737	HCT116	viability after 15 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.06904424140286833	[274]	[128,249,70]	0	hSpCas9	negative selection	2138582
38481415	38481438	3	+	26627737	HCT116	viability after 15 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	-0.2950818850388638	[528]	[234,317,188]	-3	hSpCas9	negative selection	2138583
38477419	38477442	3	-	26627737	HCT116	viability after 18 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.8965424355058591	[26]	[16,34,19]	7	hSpCas9	negative selection	2220893
38477891	38477914	3	-	26627737	HCT116	viability after 18 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.881704214330913	[492]	[342,593,366]	7	hSpCas9	negative selection	2220894
38478237	38478260	3	-	26627737	HCT116	viability after 18 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.8173686471993955	[3]	[6,1,11]	9	hSpCas9	negative selection	2220895
38479250	38479273	3	+	26627737	HCT116	viability after 18 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.5514953580080544	[862]	[194,295,365]	-5	hSpCas9	negative selection	2220896
38479791	38479814	3	-	26627737	HCT116	viability after 18 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.7760831449505656	[274]	[28,53,154]	-6	hSpCas9	negative selection	2220897
38481415	38481438	3	+	26627737	HCT116	viability after 18 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	-0.24457326400015678	[528]	[212,264,163]	-2	hSpCas9	negative selection	2220898
38454315	38454338	3	+	24336569	HL60	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	-0.409658339959983	[547]	[872]	-4	hSpCas9	negative selection	2246563
38454332	38454355	3	-	24336569	HL60	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	0.08377552328035476	[1404]	[3150]	0	hSpCas9	negative selection	2246564
38454337	38454360	3	+	24336569	HL60	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	-0.06421872021302943	[789]	[1598]	0	hSpCas9	negative selection	2246565
38477320	38477343	3	+	24336569	HL60	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	0.5327555759407524	[780]	[2390]	5	hSpCas9	negative selection	2246566
38477327	38477350	3	+	24336569	HL60	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	0.5212412222272464	[861]	[2617]	4	hSpCas9	negative selection	2246567
38477335	38477358	3	-	24336569	HL60	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	1.926355403830403	[275]	[2219]	9	hSpCas9	negative selection	2246568
38477346	38477369	3	+	24336569	HL60	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	-0.8385668565689997	[997]	[1180]	-6	hSpCas9	negative selection	2246569
38477351	38477374	3	+	24336569	HL60	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	0.4547128543894016	[400]	[1162]	4	hSpCas9	negative selection	2246570
38477356	38477379	3	-	24336569	HL60	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	0.28237763599186055	[440]	[1134]	2	hSpCas9	negative selection	2246571
38477364	38477387	3	+	24336569	HL60	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	-0.18693679918766293	[1460]	[2715]	-2	hSpCas9	negative selection	2246572
38454315	38454338	3	+	24336569	KBM7	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	-0.19861190285063884	[437]	[1040]	-2	hSpCas9	negative selection	2313740
38454332	38454355	3	-	24336569	KBM7	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	-0.44110001631354523	[1332]	[2677]	-4	hSpCas9	negative selection	2313741
38454337	38454360	3	+	24336569	KBM7	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	0.7075087562470432	[618]	[2756]	6	hSpCas9	negative selection	2313742
38477320	38477343	3	+	24336569	KBM7	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	0.24415714362432606	[728]	[2354]	2	hSpCas9	negative selection	2313743
38477327	38477350	3	+	24336569	KBM7	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	0.5535111385887106	[991]	[3970]	5	hSpCas9	negative selection	2313744
38477335	38477358	3	-	24336569	KBM7	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	0.34097813005459565	[617]	[2134]	3	hSpCas9	negative selection	2313745
38477346	38477369	3	+	24336569	KBM7	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	0.47478339205685155	[438]	[1663]	4	hSpCas9	negative selection	2313746
38477351	38477374	3	+	24336569	KBM7	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	0.7166094353442856	[279]	[1254]	6	hSpCas9	negative selection	2313747
38477356	38477379	3	-	24336569	KBM7	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	-0.775153854577387	[415]	[662]	-5	hSpCas9	negative selection	2313748
38477364	38477387	3	+	24336569	KBM7	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	0.36849564459206063	[918]	[3235]	3	hSpCas9	negative selection	2313749
38454203	38454226	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGAGACCGAAGGAAGGAGCGGG	ACVR2B	ENSG00000114739	-0.13976511187883878	[22,59]	[6,8]	0	dCas9-VP64	positive selection	2396743
38454151	38454174	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGCAGCGTTCGGGCTCCAAGG	ACVR2B	ENSG00000114739	0.24781205888943592	[12,45]	[3,10]	1	dCas9-VP64	positive selection	2396744
38454179	38454202	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGGCGCAGGAAGCGCGCAGGG	ACVR2B	ENSG00000114739	3.9424537430299207	[152,3]	[401,113]	9	dCas9-VP64	positive selection	2396745
38454203	38454226	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGAGACCGAAGGAAGGAGCGGG	ACVR2B	ENSG00000114739	-1.3880847186320358	[329,348]	[43,39]	-9	dCas9-VP64	positive selection	2491998
38454151	38454174	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGCAGCGTTCGGGCTCCAAGG	ACVR2B	ENSG00000114739	0.6007423880834187	[25,54]	[13,24]	4	dCas9-VP64	positive selection	2491999
38454179	38454202	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGGCGCAGGAAGCGCGCAGGG	ACVR2B	ENSG00000114739	-0.8905809007699884	[60,77]	[8,14]	-8	dCas9-VP64	positive selection	2492000
38477335	38477358	3	-	27260157	DLD1	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	-0.0944904695610643	[]	[]	0	hSpCas9	negative selection	2575207
38477364	38477387	3	+	27260157	DLD1	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	0.401473527731043	[]	[]	4	hSpCas9	negative selection	2575909
38477346	38477369	3	+	27260157	DLD1	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	1.23570254077158	[]	[]	9	hSpCas9	negative selection	2578281
38478237	38478260	3	-	27260157	DLD1	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.0577813490714357	[]	[]	3	hSpCas9	negative selection	2581333
38477351	38477374	3	+	27260157	DLD1	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	1.34386764771259	[]	[]	9	hSpCas9	negative selection	2581642
38454315	38454338	3	+	27260157	DLD1	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.890268353319896	[]	[]	9	hSpCas9	negative selection	2583845
38477356	38477379	3	-	27260157	DLD1	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	0.334832512133337	[]	[]	4	hSpCas9	negative selection	2584881
38478263	38478286	3	-	27260157	DLD1	viability	ATGTCCACATGACCGTAGGGGGG	ACVR2B	ENSG00000114739	0.230146947009766	[]	[]	3	hSpCas9	negative selection	2586160
38478449	38478472	3	+	27260157	DLD1	viability	GCGCTTTGGCTGTGTCTGGAAGG	ACVR2B	ENSG00000114739	-0.267496868408489	[]	[]	-2	hSpCas9	negative selection	2587610
38479152	38479175	3	+	27260157	DLD1	viability	CGGGAGATCTTCAGCACACCTGG	ACVR2B	ENSG00000114739	1.68905520548075	[]	[]	9	hSpCas9	negative selection	2605055
38454337	38454360	3	+	27260157	DLD1	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	-0.714484338736252	[]	[]	-5	hSpCas9	negative selection	2605929
38454307	38454330	3	+	27260157	DLD1	viability	GGCGGCGCCGCGGAACATGACGG	ACVR2B	ENSG00000114739	-2.13509463170328	[]	[]	-9	hSpCas9	negative selection	2607632
38477440	38477463	3	-	27260157	DLD1	viability	GCCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	1.15026432164312	[]	[]	9	hSpCas9	negative selection	2611158
38478214	38478237	3	-	27260157	DLD1	viability	CCAGCAGGACGATGAGGGAAAGG	ACVR2B	ENSG00000114739	0.559893894305894	[]	[]	8	hSpCas9	negative selection	2613949
38477320	38477343	3	+	27260157	DLD1	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	0.447207054115477	[]	[]	7	hSpCas9	negative selection	2616212
38477438	38477461	3	+	27260157	DLD1	viability	CACCATCGAGCTCGTGAAGAAGG	ACVR2B	ENSG00000114739	1.00235856469184	[]	[]	9	hSpCas9	negative selection	2620097
38477327	38477350	3	+	27260157	DLD1	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	0.0443820052706833	[]	[]	3	hSpCas9	negative selection	2642217
38478165	38478188	3	-	27260157	DLD1	viability	CAGCACCGTGAGCAGGGTGGGGG	ACVR2B	ENSG00000114739	-0.343899333016248	[]	[]	-3	hSpCas9	negative selection	2642654
38454332	38454355	3	-	27260157	DLD1	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	-1.96930430415368	[]	[]	-8	hSpCas9	negative selection	2643199
38477895	38477918	3	+	27260157	DLD1	viability	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.998132484513744	[]	[]	9	hSpCas9	negative selection	2649331
38477335	38477358	3	-	27260157	HT1080	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	-0.197340640721042	[]	[]	0	hSpCas9	negative selection	2651337
38477364	38477387	3	+	27260157	HT1080	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	0.35808907301762	[]	[]	3	hSpCas9	negative selection	2652039
38477346	38477369	3	+	27260157	HT1080	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	1.93644089193635	[]	[]	9	hSpCas9	negative selection	2654411
38478237	38478260	3	-	27260157	HT1080	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.21138621532661	[]	[]	8	hSpCas9	negative selection	2657463
38477351	38477374	3	+	27260157	HT1080	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	0.0559490599511491	[]	[]	0	hSpCas9	negative selection	2657772
38454315	38454338	3	+	27260157	HT1080	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	-0.440643277800961	[]	[]	-7	hSpCas9	negative selection	2659975
38477356	38477379	3	-	27260157	HT1080	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	0.094408082449109	[]	[]	1	hSpCas9	negative selection	2661011
38478263	38478286	3	-	27260157	HT1080	viability	ATGTCCACATGACCGTAGGGGGG	ACVR2B	ENSG00000114739	-1.00946630742521	[]	[]	-8	hSpCas9	negative selection	2662290
38478449	38478472	3	+	27260157	HT1080	viability	GCGCTTTGGCTGTGTCTGGAAGG	ACVR2B	ENSG00000114739	1.53343778572042	[]	[]	9	hSpCas9	negative selection	2663740
38479152	38479175	3	+	27260157	HT1080	viability	CGGGAGATCTTCAGCACACCTGG	ACVR2B	ENSG00000114739	1.01258367899332	[]	[]	8	hSpCas9	negative selection	2681185
38454337	38454360	3	+	27260157	HT1080	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	-0.838700310088515	[]	[]	-8	hSpCas9	negative selection	2682059
38454307	38454330	3	+	27260157	HT1080	viability	GGCGGCGCCGCGGAACATGACGG	ACVR2B	ENSG00000114739	0.411231907404721	[]	[]	4	hSpCas9	negative selection	2683762
38477440	38477463	3	-	27260157	HT1080	viability	GCCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.734758926854689	[]	[]	6	hSpCas9	negative selection	2687288
38478214	38478237	3	-	27260157	HT1080	viability	CCAGCAGGACGATGAGGGAAAGG	ACVR2B	ENSG00000114739	0.636878576934418	[]	[]	5	hSpCas9	negative selection	2690079
38477320	38477343	3	+	27260157	HT1080	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	1.34226075777735	[]	[]	9	hSpCas9	negative selection	2692342
38477438	38477461	3	+	27260157	HT1080	viability	CACCATCGAGCTCGTGAAGAAGG	ACVR2B	ENSG00000114739	1.50391178027691	[]	[]	9	hSpCas9	negative selection	2696227
38477327	38477350	3	+	27260157	HT1080	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	0.183664796129505	[]	[]	1	hSpCas9	negative selection	2718347
38478165	38478188	3	-	27260157	HT1080	viability	CAGCACCGTGAGCAGGGTGGGGG	ACVR2B	ENSG00000114739	-0.305470719276211	[]	[]	-7	hSpCas9	negative selection	2718784
38454332	38454355	3	-	27260157	HT1080	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	-0.405719721246131	[]	[]	-7	hSpCas9	negative selection	2719329
38477895	38477918	3	+	27260157	HT1080	viability	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.254129802961637	[]	[]	2	hSpCas9	negative selection	2725461
38477335	38477358	3	-	27260157	MKN45	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	0.397693733958858	[]	[]	6	hSpCas9	negative selection	2727467
38477364	38477387	3	+	27260157	MKN45	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	0.553317057921703	[]	[]	7	hSpCas9	negative selection	2728169
38477346	38477369	3	+	27260157	MKN45	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	1.45121394728542	[]	[]	9	hSpCas9	negative selection	2730541
38478237	38478260	3	-	27260157	MKN45	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.438221662752746	[]	[]	6	hSpCas9	negative selection	2733593
38477351	38477374	3	+	27260157	MKN45	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	0.867212772344123	[]	[]	8	hSpCas9	negative selection	2733902
38454315	38454338	3	+	27260157	MKN45	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	1.09449938052714	[]	[]	8	hSpCas9	negative selection	2736105
38477356	38477379	3	-	27260157	MKN45	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	0.64396814991698	[]	[]	7	hSpCas9	negative selection	2737141
38478263	38478286	3	-	27260157	MKN45	viability	ATGTCCACATGACCGTAGGGGGG	ACVR2B	ENSG00000114739	-0.768410683821496	[]	[]	-7	hSpCas9	negative selection	2738420
38478449	38478472	3	+	27260157	MKN45	viability	GCGCTTTGGCTGTGTCTGGAAGG	ACVR2B	ENSG00000114739	0.610211693332393	[]	[]	7	hSpCas9	negative selection	2739870
38479152	38479175	3	+	27260157	MKN45	viability	CGGGAGATCTTCAGCACACCTGG	ACVR2B	ENSG00000114739	1.10665418599113	[]	[]	8	hSpCas9	negative selection	2757315
38454337	38454360	3	+	27260157	MKN45	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	0.683148260511018	[]	[]	7	hSpCas9	negative selection	2758189
38454307	38454330	3	+	27260157	MKN45	viability	GGCGGCGCCGCGGAACATGACGG	ACVR2B	ENSG00000114739	-0.705832851489668	[]	[]	-7	hSpCas9	negative selection	2759892
38477440	38477463	3	-	27260157	MKN45	viability	GCCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	1.58669447330129	[]	[]	9	hSpCas9	negative selection	2763418
38478214	38478237	3	-	27260157	MKN45	viability	CCAGCAGGACGATGAGGGAAAGG	ACVR2B	ENSG00000114739	1.3474414199806	[]	[]	9	hSpCas9	negative selection	2766209
38477320	38477343	3	+	27260157	MKN45	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	1.36183204835615	[]	[]	9	hSpCas9	negative selection	2768472
38477438	38477461	3	+	27260157	MKN45	viability	CACCATCGAGCTCGTGAAGAAGG	ACVR2B	ENSG00000114739	2.51422555777654	[]	[]	9	hSpCas9	negative selection	2772357
38477327	38477350	3	+	27260157	MKN45	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	0.469846068990889	[]	[]	6	hSpCas9	negative selection	2794477
38478165	38478188	3	-	27260157	MKN45	viability	CAGCACCGTGAGCAGGGTGGGGG	ACVR2B	ENSG00000114739	0.453075962092305	[]	[]	6	hSpCas9	negative selection	2794914
38454332	38454355	3	-	27260157	MKN45	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	-0.00343680857673081	[]	[]	0	hSpCas9	negative selection	2795459
38477895	38477918	3	+	27260157	MKN45	viability	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	1.19001600898267	[]	[]	9	hSpCas9	negative selection	2801591
38477335	38477358	3	-	27260157	RKO	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	0.0410584183778396	[]	[]	0	hSpCas9	negative selection	2803597
38477364	38477387	3	+	27260157	RKO	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	0.0284461380188695	[]	[]	0	hSpCas9	negative selection	2804299
38477346	38477369	3	+	27260157	RKO	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	1.64398034945786	[]	[]	9	hSpCas9	negative selection	2806671
38478237	38478260	3	-	27260157	RKO	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-1.16128978048591	[]	[]	-8	hSpCas9	negative selection	2809723
38477351	38477374	3	+	27260157	RKO	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	0.451322211703233	[]	[]	2	hSpCas9	negative selection	2810032
38454315	38454338	3	+	27260157	RKO	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.199043086077067	[]	[]	1	hSpCas9	negative selection	2812235
38477356	38477379	3	-	27260157	RKO	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	0.188106699149736	[]	[]	1	hSpCas9	negative selection	2813271
38478263	38478286	3	-	27260157	RKO	viability	ATGTCCACATGACCGTAGGGGGG	ACVR2B	ENSG00000114739	-0.368037904950175	[]	[]	-6	hSpCas9	negative selection	2814550
38478449	38478472	3	+	27260157	RKO	viability	GCGCTTTGGCTGTGTCTGGAAGG	ACVR2B	ENSG00000114739	-0.0847405771745256	[]	[]	0	hSpCas9	negative selection	2816000
38479152	38479175	3	+	27260157	RKO	viability	CGGGAGATCTTCAGCACACCTGG	ACVR2B	ENSG00000114739	1.68533210085637	[]	[]	9	hSpCas9	negative selection	2833445
38454337	38454360	3	+	27260157	RKO	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	-1.02071621037748	[]	[]	-8	hSpCas9	negative selection	2834319
38454307	38454330	3	+	27260157	RKO	viability	GGCGGCGCCGCGGAACATGACGG	ACVR2B	ENSG00000114739	-0.499274895652673	[]	[]	-6	hSpCas9	negative selection	2836022
38477440	38477463	3	-	27260157	RKO	viability	GCCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.798357061833409	[]	[]	8	hSpCas9	negative selection	2839548
38478214	38478237	3	-	27260157	RKO	viability	CCAGCAGGACGATGAGGGAAAGG	ACVR2B	ENSG00000114739	0.497690329998247	[]	[]	2	hSpCas9	negative selection	2842339
38477320	38477343	3	+	27260157	RKO	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	0.51889225774802	[]	[]	2	hSpCas9	negative selection	2844602
38477438	38477461	3	+	27260157	RKO	viability	CACCATCGAGCTCGTGAAGAAGG	ACVR2B	ENSG00000114739	1.46635124912678	[]	[]	9	hSpCas9	negative selection	2848487
38477327	38477350	3	+	27260157	RKO	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	0.327348035515985	[]	[]	1	hSpCas9	negative selection	2870607
38478165	38478188	3	-	27260157	RKO	viability	CAGCACCGTGAGCAGGGTGGGGG	ACVR2B	ENSG00000114739	-1.92247831141773	[]	[]	-9	hSpCas9	negative selection	2871044
38454332	38454355	3	-	27260157	RKO	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	-1.18235651868312	[]	[]	-8	hSpCas9	negative selection	2871589
38477895	38477918	3	+	27260157	RKO	viability	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.864162207591028	[]	[]	8	hSpCas9	negative selection	2877721
38477335	38477358	3	-	27260157	SF268	viability	GGTGCGCTCCAGCTCCCAGTTGG	ACVR2B	ENSG00000114739	-0.241729696237494	[]	[]	-2	hSpCas9	negative selection	2879727
38477364	38477387	3	+	27260157	SF268	viability	AGCGGCCTGGAGCGCTGCGAAGG	ACVR2B	ENSG00000114739	0.943268540920674	[]	[]	9	hSpCas9	negative selection	2880429
38477346	38477369	3	+	27260157	SF268	viability	CTGGAGCGCACCAACCAGAGCGG	ACVR2B	ENSG00000114739	0.739143811843546	[]	[]	8	hSpCas9	negative selection	2882801
38478237	38478260	3	-	27260157	SF268	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.706811785988506	[]	[]	-5	hSpCas9	negative selection	2885853
38477351	38477374	3	+	27260157	SF268	viability	GCGCACCAACCAGAGCGGCCTGG	ACVR2B	ENSG00000114739	0.159623916171864	[]	[]	0	hSpCas9	negative selection	2886162
38454315	38454338	3	+	27260157	SF268	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.50565998822822	[]	[]	7	hSpCas9	negative selection	2888365
38477356	38477379	3	-	27260157	SF268	viability	GCGCTCCAGGCCGCTCTGGTTGG	ACVR2B	ENSG00000114739	0.0412652548560656	[]	[]	0	hSpCas9	negative selection	2889401
38478263	38478286	3	-	27260157	SF268	viability	ATGTCCACATGACCGTAGGGGGG	ACVR2B	ENSG00000114739	0.187959995267077	[]	[]	0	hSpCas9	negative selection	2890680
38478449	38478472	3	+	27260157	SF268	viability	GCGCTTTGGCTGTGTCTGGAAGG	ACVR2B	ENSG00000114739	0.146142532344426	[]	[]	0	hSpCas9	negative selection	2892130
38479152	38479175	3	+	27260157	SF268	viability	CGGGAGATCTTCAGCACACCTGG	ACVR2B	ENSG00000114739	1.57089918999071	[]	[]	9	hSpCas9	negative selection	2909575
38454337	38454360	3	+	27260157	SF268	viability	GGTGGCCCTCGCCCTCCTCTGGG	ACVR2B	ENSG00000114739	-0.634400636481075	[]	[]	-5	hSpCas9	negative selection	2910449
38454307	38454330	3	+	27260157	SF268	viability	GGCGGCGCCGCGGAACATGACGG	ACVR2B	ENSG00000114739	-1.12435372448991	[]	[]	-7	hSpCas9	negative selection	2912152
38477440	38477463	3	-	27260157	SF268	viability	GCCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.872115009724575	[]	[]	9	hSpCas9	negative selection	2915678
38478214	38478237	3	-	27260157	SF268	viability	CCAGCAGGACGATGAGGGAAAGG	ACVR2B	ENSG00000114739	0.693512014914938	[]	[]	8	hSpCas9	negative selection	2918469
38477320	38477343	3	+	27260157	SF268	viability	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	1.62303946752885	[]	[]	9	hSpCas9	negative selection	2920732
38477438	38477461	3	+	27260157	SF268	viability	CACCATCGAGCTCGTGAAGAAGG	ACVR2B	ENSG00000114739	1.87937931371342	[]	[]	9	hSpCas9	negative selection	2924617
38477327	38477350	3	+	27260157	SF268	viability	CTACAACGCCAACTGGGAGCTGG	ACVR2B	ENSG00000114739	-0.304310389571469	[]	[]	-2	hSpCas9	negative selection	2946737
38478165	38478188	3	-	27260157	SF268	viability	CAGCACCGTGAGCAGGGTGGGGG	ACVR2B	ENSG00000114739	-0.056081644151116	[]	[]	0	hSpCas9	negative selection	2947174
38454332	38454355	3	-	27260157	SF268	viability	AGGAGGGCGAGGGCCACCCAGGG	ACVR2B	ENSG00000114739	-0.0748292859400506	[]	[]	0	hSpCas9	negative selection	2947719
38477895	38477918	3	+	27260157	SF268	viability	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.114814014482939	[]	[]	0	hSpCas9	negative selection	2953851
38477890	38477913	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.04711830110268965	[3,3]	[1,4]	0	hSpCas9	positive selection	2968799
38478272	38478295	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	-0.3318111257548552	[3,3]	[2,1]	-5	hSpCas9	positive selection	2968800
38477381	38477404	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	-0.07008687658750871	[3,3]	[3,1]	-1	hSpCas9	positive selection	2968801
38478237	38478260	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.13727910585225966	[3,3]	[3,3]	3	hSpCas9	positive selection	2968802
38477890	38477913	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.31174709973750325	[3,3]	[2,1]	-5	hSpCas9	positive selection	3036657
38478272	38478295	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	0.015910844469072177	[3,3]	[2,2]	0	hSpCas9	positive selection	3036658
38477381	38477404	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	-0.8025700178210764	[3,3]	[1,0]	-9	hSpCas9	positive selection	3036659
38478237	38478260	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.05294669449301018	[3,3]	[2,2]	0	hSpCas9	positive selection	3036660
38454352	38454375		-	24336571	A375	resistance to PLX after 7 days	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.059049555977684506	[11,11]	[9,13]	2	hSpCas9	positive selection	3160577
38477895	38477918		+	24336571	A375	resistance to PLX after 7 days	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.38046365477573896	[13,12]	[17,17]	8	hSpCas9	positive selection	3160588
38454352	38454375		-	24336571	A375	resistance to PLX after 14 days	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.5794779216824141	[18,11]	[5,2]	-7	hSpCas9	positive selection	3218370
38477895	38477918		+	24336571	A375	resistance to PLX after 14 days	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.4114562489152021	[16,12]	[9,8]	4	hSpCas9	positive selection	3218381
38454352	38454375		-	24336571	A375	viability after 7 days	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.08589588763325748	[12]	[11,11]	-1	hSpCas9	negative selection	3276163
38477895	38477918		+	24336571	A375	viability after 7 days	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	-0.11028384519829999	[15]	[13,12]	-1	hSpCas9	negative selection	3276174
38454352	38454375		-	24336571	A375	viability after 14 days	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.29879086599644056	[12]	[18,11]	4	hSpCas9	negative selection	3333956
38477895	38477918		+	24336571	A375	viability after 14 days	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.028688679226949676	[15]	[16,12]	0	hSpCas9	negative selection	3333967
38478237	38478260	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	4.7987520638833425	[4,5]	[0,0]	9	hSpCas9	positive selection	3335478
38478251	38478274	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	-0.7178942433303175	[272,229]	[0,0]	-5	hSpCas9	positive selection	3335479
38454315	38454338	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	-0.054488871812792626	[140,176]	[0,0]	0	hSpCas9	positive selection	3335480
38454352	38454375	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.5158592250446882	[106,106]	[0,0]	2	hSpCas9	positive selection	3354724
38477891	38477914	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.4080097057393411	[202,202]	[0,0]	-3	hSpCas9	positive selection	3354725
38477933	38477956	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3354726
38477890	38477913	3	-	26780180	HT29	viability (Avana library 4 designs)	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	1.16693928001147	[]	[]	4	hSpCas9	negative selection	3404749
38478271	38478294	3	+	26780180	HT29	viability (Avana library 4 designs)	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	0.287649156838992	[]	[]	1	hSpCas9	negative selection	3404750
38477380	38477403	3	+	26780180	HT29	viability (Avana library 4 designs)	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	1.1698777430016	[]	[]	4	hSpCas9	negative selection	3404751
38478237	38478260	3	-	26780180	HT29	viability (Avana library 4 designs)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.913387525816886	[]	[]	-9	hSpCas9	negative selection	3404752
38477890	38477913	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.234738298835549	[]	[]	0	hSpCas9	negative selection	3476439
38478271	38478294	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	3.62284074265251	[]	[]	6	hSpCas9	negative selection	3476440
38477380	38477403	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	0.315968916118461	[]	[]	0	hSpCas9	negative selection	3476441
38478237	38478260	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	5.41508211759671	[]	[]	8	hSpCas9	negative selection	3476442
38477320	38477343	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	-8.79401512677901	[]	[]	-7	hSpCas9	negative selection	3476443
38454348	38454371	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAGCGATCCCCAGAGGAGGG	ACVR2B	ENSG00000114739	1.89377109591638	[]	[]	2	hSpCas9	negative selection	3476444
38477890	38477913	3	-	26780180	A375	viability (Avana lentiGuide)	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-5.10229531029464	[]	[]	-8	hSpCas9	negative selection	3585098
38478271	38478294	3	+	26780180	A375	viability (Avana lentiGuide)	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	-1.82620629871515	[]	[]	-3	hSpCas9	negative selection	3585099
38477380	38477403	3	+	26780180	A375	viability (Avana lentiGuide)	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	-2.28411241132347	[]	[]	-4	hSpCas9	negative selection	3585100
38478237	38478260	3	-	26780180	A375	viability (Avana lentiGuide)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-3.75874824005986	[]	[]	-6	hSpCas9	negative selection	3585101
38477320	38477343	3	+	26780180	A375	viability (Avana lentiGuide)	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	-3.36918641474445	[]	[]	-6	hSpCas9	negative selection	3585102
38454348	38454371	3	-	26780180	A375	viability (Avana lentiGuide)	GCACAGCGATCCCCAGAGGAGGG	ACVR2B	ENSG00000114739	1.31427518943919	[]	[]	1	hSpCas9	negative selection	3585103
38477890	38477913	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.28098682240426887	[5]	[4,3]	-4	hSpCas9	positive selection	3693757
38478271	38478294	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	0.19995977990921326	[4]	[5,4]	5	hSpCas9	positive selection	3693758
38477380	38477403	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	0.11786949519117387	[4]	[4,3]	3	hSpCas9	positive selection	3693759
38478237	38478260	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.2819923429481975	[4]	[6,5]	7	hSpCas9	positive selection	3693760
38477320	38477343	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	-0.8442701344667307	[4]	[1,2]	-8	hSpCas9	positive selection	3693761
38454348	38454371	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAGCGATCCCCAGAGGAGGG	ACVR2B	ENSG00000114739	0.14323137454950385	[5]	[5,5]	4	hSpCas9	positive selection	3693762
38477890	38477913	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.0765888986444011	[5]	[4,5]	1	hSpCas9	positive selection	3802364
38478271	38478294	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGTCATGTGGACATCCATGAGG	ACVR2B	ENSG00000114739	-0.00675194029701124	[5]	[5,3]	0	hSpCas9	positive selection	3802365
38477380	38477403	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAAGGCGAGCAGGACAAGCGG	ACVR2B	ENSG00000114739	0.21513245934843703	[4]	[5,3]	5	hSpCas9	positive selection	3802366
38478237	38478260	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.3708532306656508	[5]	[6,6]	9	hSpCas9	positive selection	3802367
38477320	38477343	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCTACTACAACGCCAACTGG	ACVR2B	ENSG00000114739	0.28362319010813	[5]	[6,5]	7	hSpCas9	positive selection	3802368
38454348	38454371	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAGCGATCCCCAGAGGAGGG	ACVR2B	ENSG00000114739	0.15518587267216932	[5]	[5,5]	3	hSpCas9	positive selection	3802369
38477933	38477956	3	+	26780180	A375	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.661174062816527	[]	[]	2	hSpCas9	negative selection	3910964
38477891	38477914	3	-	26780180	A375	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	1.44541446403174	[]	[]	8	hSpCas9	negative selection	3910965
38454315	38454338	3	+	26780180	A375	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	1.35997554691406	[]	[]	7	hSpCas9	negative selection	3910966
38478251	38478274	3	+	26780180	A375	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.415460538499287	[]	[]	1	hSpCas9	negative selection	3910967
38454352	38454375	3	-	26780180	A375	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	1.19551675825579	[]	[]	6	hSpCas9	negative selection	3910968
38478237	38478260	3	-	26780180	A375	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.171446964069047	[]	[]	0	hSpCas9	negative selection	3910969
38477933	38477956	3	+	26780180	HT29	viability (GeCKOv2 library)	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	1.07564208885657	[]	[]	5	hSpCas9	negative selection	4018930
38477891	38477914	3	-	26780180	HT29	viability (GeCKOv2 library)	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	2.46780312034144	[]	[]	9	hSpCas9	negative selection	4018931
38454315	38454338	3	+	26780180	HT29	viability (GeCKOv2 library)	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	1.24306691864405	[]	[]	6	hSpCas9	negative selection	4018932
38478251	38478274	3	+	26780180	HT29	viability (GeCKOv2 library)	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.38982545948621	[]	[]	1	hSpCas9	negative selection	4018933
38454352	38454375	3	-	26780180	HT29	viability (GeCKOv2 library)	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.967242139051105	[]	[]	4	hSpCas9	negative selection	4018934
38478237	38478260	3	-	26780180	HT29	viability (GeCKOv2 library)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.344193074207002	[]	[]	0	hSpCas9	negative selection	4018935
38454352	38454375	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.12680793914480987	[3]	[1,1]	-3	hSpCas9	positive selection	4188664
38477895	38477918	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	0.7502477280453393	[3]	[6,3]	9	hSpCas9	positive selection	4188675
38454352	38454375	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.4019427143046407	[4]	[0,3,1,0]	-6	hSpCas9	positive selection	4252686
38477895	38477918	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTACTTCTGCTGCTGTGAAGG	ACVR2B	ENSG00000114739	-0.1757919267362027	[4]	[0,3,2,0]	-3	hSpCas9	positive selection	4252697
38478237	38478260	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.34775529197609023	[0]	[0,0]	7	hSpCas9	positive selection	4254401
38478251	38478274	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	-0.024338631484739907	[3]	[3,1]	0	hSpCas9	positive selection	4254402
38454315	38454338	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.22659088857762394	[3]	[2,3]	4	hSpCas9	positive selection	4254403
38454352	38454375	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.3795074642208063	[2]	[2,2]	7	hSpCas9	positive selection	4318684
38477891	38477914	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.1446581293069551	[2]	[2,0]	-3	hSpCas9	positive selection	4318685
38477933	38477956	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.2587378067885835	[2]	[2,0]	-5	hSpCas9	positive selection	4318686
38477322	38477344	3	+	27760321	OCIAML3	viability	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	-0.5805139390482664	[447,423]	[173,298]	-5	hSpCas9	negative selection	4376000
38477440	38477462	3	-	27760321	OCIAML3	viability	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.543789621937347	[614,562]	[268,376]	-5	hSpCas9	negative selection	4376001
38477474	38477496	3	+	27760321	OCIAML3	viability	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.42163229524233253	[549,527]	[578,547]	5	hSpCas9	negative selection	4376002
38478137	38478159	3	-	27760321	OCIAML3	viability	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-1.1962654057233804	[652,579]	[124,320]	-8	hSpCas9	negative selection	4376003
38478237	38478259	3	-	27760321	OCIAML3	viability	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.3561668668574095	[319,269]	[189,165]	-4	hSpCas9	negative selection	4376004
38477322	38477344	3	+	27760321	OCIAML2	viability	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.30283841971717224	[447,423]	[315,592]	4	hSpCas9	negative selection	4459463
38477440	38477462	3	-	27760321	OCIAML2	viability	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.15733658640811182	[614,562]	[411,446]	-2	hSpCas9	negative selection	4459464
38477474	38477496	3	+	27760321	OCIAML2	viability	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.3442271865348369	[549,527]	[430,716]	5	hSpCas9	negative selection	4459465
38478137	38478159	3	-	27760321	OCIAML2	viability	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	0.1962507963728028	[652,579]	[497,665]	2	hSpCas9	negative selection	4459466
38478237	38478259	3	-	27760321	OCIAML2	viability	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.6989555255125612	[319,269]	[243,572]	8	hSpCas9	negative selection	4459467
38477322	38477344	3	+	27760321	MV411	viability	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	1.7817072736977848	[447,423]	[1325,485]	9	hSpCas9	negative selection	4542926
38477440	38477462	3	-	27760321	MV411	viability	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.8052243169431611	[614,562]	[387,1115]	6	hSpCas9	negative selection	4542927
38477474	38477496	3	+	27760321	MV411	viability	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.2521594368346079	[549,527]	[303,604]	1	hSpCas9	negative selection	4542928
38478137	38478159	3	-	27760321	MV411	viability	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-0.5549755943715907	[652,579]	[130,494]	-4	hSpCas9	negative selection	4542929
38478237	38478259	3	-	27760321	MV411	viability	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.2077276742015264	[319,269]	[190,833]	8	hSpCas9	negative selection	4542930
38477322	38477344	3	+	27760321	HL60	viability	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.600983934161841	[447,423]	[482,601]	7	hSpCas9	negative selection	4626389
38477440	38477462	3	-	27760321	HL60	viability	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.5249108408569313	[614,562]	[326,341]	-5	hSpCas9	negative selection	4626390
38477474	38477496	3	+	27760321	HL60	viability	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.5835437762197504	[549,527]	[506,823]	7	hSpCas9	negative selection	4626391
38478137	38478159	3	-	27760321	HL60	viability	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-0.0858178650146027	[652,579]	[515,428]	-1	hSpCas9	negative selection	4626392
38478237	38478259	3	-	27760321	HL60	viability	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.2102481810150756	[319,269]	[257,870]	9	hSpCas9	negative selection	4626393
38477322	38477344	3	+	27760321	HT1080	viability	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.23917939539869026	[423,330]	[145,211]	1	hSpCas9	negative selection	4709852
38477440	38477462	3	-	27760321	HT1080	viability	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.20220506356723983	[562,439]	[247,209]	1	hSpCas9	negative selection	4709853
38477474	38477496	3	+	27760321	HT1080	viability	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.4573341615507311	[527,411]	[110,416]	2	hSpCas9	negative selection	4709854
38478137	38478159	3	-	27760321	HT1080	viability	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	0.09229946240955167	[579,452]	[226,210]	0	hSpCas9	negative selection	4709855
38478237	38478259	3	-	27760321	HT1080	viability	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.2599501888165182	[269,210]	[111,44]	-1	hSpCas9	negative selection	4709856
38477322	38477344	3	+	27760321	HT29	viability after 7 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.14758106758651623	[423,330]	[661,592,379]	2	hSpCas9	negative selection	4793315
38477440	38477462	3	-	27760321	HT29	viability after 7 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.07636195548919822	[562,439]	[608,468,750]	-1	hSpCas9	negative selection	4793316
38477474	38477496	3	+	27760321	HT29	viability after 7 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	-0.08136479682663522	[527,411]	[732,441,560]	-1	hSpCas9	negative selection	4793317
38478137	38478159	3	-	27760321	HT29	viability after 7 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-0.36279068639594486	[579,452]	[547,644,364]	-5	hSpCas9	negative selection	4793318
38478237	38478259	3	-	27760321	HT29	viability after 7 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.18734002690953672	[269,210]	[476,350,248]	3	hSpCas9	negative selection	4793319
38477322	38477344	3	+	27760321	HT29	viability after 25 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.3574826061761822	[423,330]	[662,489,490]	4	hSpCas9	negative selection	4876778
38477440	38477462	3	-	27760321	HT29	viability after 25 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.17398034450730165	[562,439]	[573,709,660]	1	hSpCas9	negative selection	4876779
38477474	38477496	3	+	27760321	HT29	viability after 25 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.24630334854534447	[527,411]	[721,571,607]	2	hSpCas9	negative selection	4876780
38478137	38478159	3	-	27760321	HT29	viability after 25 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	0.07101293724632762	[579,452]	[592,578,696]	0	hSpCas9	negative selection	4876781
38478237	38478259	3	-	27760321	HT29	viability after 25 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.3219896713012695	[269,210]	[411,252,362]	3	hSpCas9	negative selection	4876782
38477322	38477344	3	+	27760321	HT29	viability after 22 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.07819595517683711	[423,330]	[398,504,479]	0	hSpCas9	negative selection	4960241
38477440	38477462	3	-	27760321	HT29	viability after 22 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.1669873830633995	[562,439]	[751,558,638]	1	hSpCas9	negative selection	4960242
38477474	38477496	3	+	27760321	HT29	viability after 22 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.05766960212756267	[527,411]	[663,547,480]	0	hSpCas9	negative selection	4960243
38478137	38478159	3	-	27760321	HT29	viability after 22 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	0.014851653513079266	[579,452]	[527,672,610]	0	hSpCas9	negative selection	4960244
38478237	38478259	3	-	27760321	HT29	viability after 22 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.10201030510304371	[269,210]	[311,377,203]	1	hSpCas9	negative selection	4960245
38477322	38477344	3	+	27760321	HT29	viability after 19 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.24609944052148625	[423,330]	[527,350,652]	2	hSpCas9	negative selection	5043704
38477440	38477462	3	-	27760321	HT29	viability after 19 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.38728015119609605	[562,439]	[757,451,149]	-4	hSpCas9	negative selection	5043705
38477474	38477496	3	+	27760321	HT29	viability after 19 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.14909293483704816	[527,411]	[584,375,816]	1	hSpCas9	negative selection	5043706
38478137	38478159	3	-	27760321	HT29	viability after 19 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-0.2055785359502854	[579,452]	[469,145,900]	-2	hSpCas9	negative selection	5043707
38478237	38478259	3	-	27760321	HT29	viability after 19 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.4836344037638614	[269,210]	[333,420,392]	5	hSpCas9	negative selection	5043708
38477322	38477344	3	+	27760321	HT29	viability after 16 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	-0.15705858396610686	[423,330]	[251,199,676]	-2	hSpCas9	negative selection	5127167
38477440	38477462	3	-	27760321	HT29	viability after 16 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.5017336383011722	[562,439]	[497,489,207]	-5	hSpCas9	negative selection	5127168
38477474	38477496	3	+	27760321	HT29	viability after 16 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	0.20733476719427563	[527,411]	[872,427,549]	2	hSpCas9	negative selection	5127169
38478137	38478159	3	-	27760321	HT29	viability after 16 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	0.007914667351409777	[579,452]	[517,471,749]	0	hSpCas9	negative selection	5127170
38478237	38478259	3	-	27760321	HT29	viability after 16 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.6813654653056683	[269,210]	[364,555,363]	7	hSpCas9	negative selection	5127171
38477322	38477344	3	+	27760321	HT29	viability after 13 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	-0.13053532333745346	[423,330]	[284,559,357]	-1	hSpCas9	negative selection	5210630
38477440	38477462	3	-	27760321	HT29	viability after 13 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.204209747778355	[562,439]	[799,492,237]	-2	hSpCas9	negative selection	5210631
38477474	38477496	3	+	27760321	HT29	viability after 13 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	-0.06484317314401356	[527,411]	[573,508,482]	-1	hSpCas9	negative selection	5210632
38478137	38478159	3	-	27760321	HT29	viability after 13 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-0.17822856226598688	[579,452]	[561,418,602]	-2	hSpCas9	negative selection	5210633
38478237	38478259	3	-	27760321	HT29	viability after 13 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.4051414646008298	[269,210]	[245,378,476]	5	hSpCas9	negative selection	5210634
38477322	38477344	3	+	27760321	HT29	viability after 10 days	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.11989689012816648	[423,330]	[576,493,465]	1	hSpCas9	negative selection	5294093
38477440	38477462	3	-	27760321	HT29	viability after 10 days	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	-0.23714888045496985	[562,439]	[519,500,570]	-3	hSpCas9	negative selection	5294094
38477474	38477496	3	+	27760321	HT29	viability after 10 days	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	-0.2512693761161376	[527,411]	[464,385,621]	-3	hSpCas9	negative selection	5294095
38478137	38478159	3	-	27760321	HT29	viability after 10 days	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	-0.4038942926650596	[579,452]	[493,379,582]	-5	hSpCas9	negative selection	5294096
38478237	38478259	3	-	27760321	HT29	viability after 10 days	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.35775715245106593	[269,210]	[409,445,301]	5	hSpCas9	negative selection	5294097
38477322	38477344	3	+	27760321	MOLM13	viability	ATCTACTACAACGCCAACTGGG	ACVR2B	ENSG00000114739	0.3855050612958869	[447,423]	[157,460]	2	hSpCas9	negative selection	5377556
38477440	38477462	3	-	27760321	MOLM13	viability	CCCTTCTTCACGAGCTCGATGG	ACVR2B	ENSG00000114739	0.6076445526971274	[614,562]	[395,599]	4	hSpCas9	negative selection	5377557
38477474	38477496	3	+	27760321	MOLM13	viability	TGACTTCAACTGCTACGATAGG	ACVR2B	ENSG00000114739	-1.0523541084571701	[549,527]	[188,110]	-6	hSpCas9	negative selection	5377558
38478137	38478159	3	-	27760321	MOLM13	viability	GGGGTGGCTCGTACGTGACTGG	ACVR2B	ENSG00000114739	1.0355674132381645	[652,579]	[672,744]	7	hSpCas9	negative selection	5377559
38478237	38478259	3	-	27760321	MOLM13	viability	CGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.2828612540526243	[319,269]	[369,431]	8	hSpCas9	negative selection	5377560
38454307	38454330	3	+	27661255	K562	viability	GGCGGCGCCGCGGAACATGACGG	ACVR2B	ENSG00000114739	0.2651698646830783	[541,719]	[613,592]	8	dCas9-KRAB	negative selection	5460819
38454364	38454387	3	+	27661255	K562	viability	GCTGTGCGCCGGTAAGAACTGGG	ACVR2B	ENSG00000114739	0.04690008219606334	[474,481]	[485,316]	1	dCas9-KRAB	negative selection	5460820
38454014	38454037	3	-	27661255	K562	viability	GACTCAGGCATAGCGCGGCGGGG	ACVR2B	ENSG00000114739	0.5863588895502931	[48,63]	[47,83]	9	dCas9-KRAB	negative selection	5460821
38454116	38454139	3	-	27661255	K562	viability	GGCCGGGCTCAGGGCCGCTGCGG	ACVR2B	ENSG00000114739	-0.04766060530031008	[562,690]	[532,439]	-2	dCas9-KRAB	negative selection	5460822
38478237	38478260	3	-	27260156	BXPC3	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.6805778711793216	[20]	[21,28,45,46]	9	hSpCas9	negative selection	5526861
38478251	38478274	3	+	27260156	BXPC3	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.5646465027129686	[523]	[669,715,958,928]	9	hSpCas9	negative selection	5526862
38454315	38454338	3	+	27260156	BXPC3	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.2651544053502781	[700]	[681,917,867,1094]	6	hSpCas9	negative selection	5526863
38454352	38454375	3	-	27260156	BXPC3	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.06005789016619667	[269]	[273,237,245,331]	-1	hSpCas9	negative selection	5591144
38477891	38477914	3	-	27260156	BXPC3	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.019469803661516016	[336]	[336,342,381,368]	0	hSpCas9	negative selection	5591145
38477933	38477956	3	+	27260156	BXPC3	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.034798320665226146	[285]	[266,272,300,399]	0	hSpCas9	negative selection	5591146
38478237	38478260	3	-	27260156	A673	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.4562603296111307	[20]	[44,15,42,35]	8	hSpCas9	negative selection	5648112
38478251	38478274	3	+	27260156	A673	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.32422529630340186	[523]	[736,746,868,790]	7	hSpCas9	negative selection	5648113
38454315	38454338	3	+	27260156	A673	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.19033271641442917	[700]	[1063,1014,966,794]	4	hSpCas9	negative selection	5648114
38454352	38454375	3	-	27260156	A673	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.3004582934384686	[269]	[407,350,368,474]	7	hSpCas9	negative selection	5712395
38477891	38477914	3	-	27260156	A673	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.12828628073933107	[336]	[447,381,423,520]	3	hSpCas9	negative selection	5712396
38477933	38477956	3	+	27260156	A673	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.2760066029216586	[285]	[408,422,361,470]	6	hSpCas9	negative selection	5712397
38478237	38478260	3	-	27260156	A375	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.5800395148474928	[20]	[65,30,21,27]	8	hSpCas9	negative selection	5769363
38478251	38478274	3	+	27260156	A375	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.5133337682115682	[523]	[963,1019,719,814]	7	hSpCas9	negative selection	5769364
38454315	38454338	3	+	27260156	A375	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.12865544712519472	[700]	[997,1016,871,727]	1	hSpCas9	negative selection	5769365
38454352	38454375	3	-	27260156	A375	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.028290121394452195	[269]	[332,229,410,300]	0	hSpCas9	negative selection	5833646
38477891	38477914	3	-	27260156	A375	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.5039035009986523	[336]	[495,901,461,432]	7	hSpCas9	negative selection	5833647
38477933	38477956	3	+	27260156	A375	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.3292207119075179	[285]	[399,626,316,367]	5	hSpCas9	negative selection	5833648
38478237	38478260	3	-	27260156	COLO741	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.1270205023881319	[20]	[30,15,26]	-3	hSpCas9	negative selection	5890614
38478251	38478274	3	+	27260156	COLO741	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.525691457696061	[523]	[1108,1017,787]	9	hSpCas9	negative selection	5890615
38454315	38454338	3	+	27260156	COLO741	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.09617260302242392	[700]	[1055,944,882]	2	hSpCas9	negative selection	5890616
38454352	38454375	3	-	27260156	COLO741	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.18362073233232112	[269]	[401,244,273]	-4	hSpCas9	negative selection	5954897
38477891	38477914	3	-	27260156	COLO741	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.011178247918887163	[336]	[492,417,378]	0	hSpCas9	negative selection	5954898
38477933	38477956	3	+	27260156	COLO741	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.44196277731172295	[285]	[396,573,507]	8	hSpCas9	negative selection	5954899
38478237	38478260	3	-	27260156	CAL120	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.2298432274307851	[20]	[42,6,19]	-3	hSpCas9	negative selection	6011865
38478251	38478274	3	+	27260156	CAL120	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.5100267242069323	[523]	[1017,694,1082]	7	hSpCas9	negative selection	6011866
38454315	38454338	3	+	27260156	CAL120	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.06387452211618427	[700]	[1146,743,879]	1	hSpCas9	negative selection	6011867
38454352	38454375	3	-	27260156	CAL120	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.35697721954849393	[269]	[396,584,305]	5	hSpCas9	negative selection	6076148
38477891	38477914	3	-	27260156	CAL120	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.1691509296182031	[336]	[223,617,533]	2	hSpCas9	negative selection	6076149
38477933	38477956	3	+	27260156	CAL120	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.09619728080453782	[285]	[582,396,194]	1	hSpCas9	negative selection	6076150
38478237	38478260	3	-	27260156	CADOES1	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.3570417128859562	[20]	[3,9,62,22]	6	hSpCas9	negative selection	6133116
38478251	38478274	3	+	27260156	CADOES1	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.4847142182978001	[523]	[605,587,896,634]	7	hSpCas9	negative selection	6133117
38454315	38454338	3	+	27260156	CADOES1	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.24493859535384266	[700]	[763,798,742,784]	4	hSpCas9	negative selection	6133118
38454352	38454375	3	-	27260156	CADOES1	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.18404449009390778	[269]	[189,176,222,296]	-3	hSpCas9	negative selection	6197399
38477891	38477914	3	-	27260156	CADOES1	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.12181739796874419	[336]	[358,313,249,444]	2	hSpCas9	negative selection	6197400
38477933	38477956	3	+	27260156	CADOES1	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.07102278410841234	[285]	[342,236,268,267]	1	hSpCas9	negative selection	6197401
38478237	38478260	3	-	27260156	EWS502	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.476319221048195	[20]	[25,1,23,10]	-7	hSpCas9	negative selection	6254367
38478251	38478274	3	+	27260156	EWS502	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.5242149943224137	[523]	[823,889,587,883]	8	hSpCas9	negative selection	6254368
38454315	38454338	3	+	27260156	EWS502	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.04426813594096002	[700]	[676,960,733,683]	0	hSpCas9	negative selection	6254369
38454352	38454375	3	-	27260156	EWS502	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.35860032292879074	[269]	[335,309,292,543]	6	hSpCas9	negative selection	6318650
38477891	38477914	3	-	27260156	EWS502	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.16671149104848987	[336]	[379,502,414,293]	3	hSpCas9	negative selection	6318651
38477933	38477956	3	+	27260156	EWS502	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.47093031135576663	[285]	[310,574,443,349]	7	hSpCas9	negative selection	6318652
38478237	38478260	3	-	27260156	EW8	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.5193361763590274	[20]	[25,13,9,49]	8	hSpCas9	negative selection	6375618
38478251	38478274	3	+	27260156	EW8	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.38956374640284935	[523]	[816,634,475,338]	7	hSpCas9	negative selection	6375619
38454315	38454338	3	+	27260156	EW8	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.20433943246074027	[700]	[752,723,461,720]	4	hSpCas9	negative selection	6375620
38454352	38454375	3	-	27260156	EW8	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.09921363881246104	[269]	[214,280,169,157]	-2	hSpCas9	negative selection	6439901
38477891	38477914	3	-	27260156	EW8	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.4566264963479696	[336]	[422,417,277,400]	7	hSpCas9	negative selection	6439902
38477933	38477956	3	+	27260156	EW8	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.053284740793498764	[285]	[244,242,243,159]	-1	hSpCas9	negative selection	6439903
38478237	38478260	3	-	27260156	CORL105	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.7998350864099057	[20]	[94,25,14,32]	9	hSpCas9	negative selection	6496869
38478251	38478274	3	+	27260156	CORL105	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.4500623418644026	[523]	[965,664,891,844]	8	hSpCas9	negative selection	6496870
38454315	38454338	3	+	27260156	CORL105	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.4169051036776482	[700]	[1084,1066,1094,1134]	7	hSpCas9	negative selection	6496871
38454352	38454375	3	-	27260156	CORL105	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.3583779494981555	[269]	[378,295,583,390]	6	hSpCas9	negative selection	6561152
38477891	38477914	3	-	27260156	CORL105	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.5122374027277288	[336]	[612,423,664,568]	8	hSpCas9	negative selection	6561153
38477933	38477956	3	+	27260156	CORL105	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.07622565008827642	[285]	[277,242,430,335]	-1	hSpCas9	negative selection	6561154
38478237	38478260	3	-	27260156	HS294T	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	2.546472662047632	[20]	[19,134,12,15]	9	hSpCas9	negative selection	6618120
38478251	38478274	3	+	27260156	HS294T	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.38884648801345184	[523]	[227,259,290,288]	5	hSpCas9	negative selection	6618121
38454315	38454338	3	+	27260156	HS294T	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.8005195136989092	[700]	[470,471,425,526]	8	hSpCas9	negative selection	6618122
38454352	38454375	3	-	27260156	HS294T	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.17507288616264893	[269]	[126,51,73,118]	-2	hSpCas9	negative selection	6682403
38477891	38477914	3	-	27260156	HS294T	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.25575370873542824	[336]	[184,120,123,196]	3	hSpCas9	negative selection	6682404
38477933	38477956	3	+	27260156	HS294T	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.43395879358990275	[285]	[53,97,71,109]	-6	hSpCas9	negative selection	6682405
38478237	38478260	3	-	27260156	HCC44	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.8802174026650893	[20]	[3,229,77,9]	9	hSpCas9	negative selection	6739371
38478251	38478274	3	+	27260156	HCC44	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.27259948202949696	[523]	[917,706,784,486]	4	hSpCas9	negative selection	6739372
38454315	38454338	3	+	27260156	HCC44	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.10412714396145795	[700]	[936,674,1133,740]	1	hSpCas9	negative selection	6739373
38454352	38454375	3	-	27260156	HCC44	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.16523979401723488	[269]	[208,210,382,304]	-3	hSpCas9	negative selection	6803654
38477891	38477914	3	-	27260156	HCC44	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.2696386784334233	[336]	[436,388,534,492]	4	hSpCas9	negative selection	6803655
38477933	38477956	3	+	27260156	HCC44	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.16735746465214996	[285]	[319,261,355,231]	-3	hSpCas9	negative selection	6803656
38478237	38478260	3	-	27260156	G402	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.5131557244089997	[20]	[0,35,7,24]	-6	hSpCas9	negative selection	6860622
38478251	38478274	3	+	27260156	G402	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.6031875981189851	[523]	[673,1624,1233,372]	7	hSpCas9	negative selection	6860623
38454315	38454338	3	+	27260156	G402	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	-0.2764021831959877	[700]	[734,1051,513,552]	-3	hSpCas9	negative selection	6860624
38454352	38454375	3	-	27260156	G402	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.013084343127723552	[269]	[278,494,342,196]	0	hSpCas9	negative selection	6924905
38477891	38477914	3	-	27260156	G402	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.8016335138599255	[336]	[628,1012,852,389]	8	hSpCas9	negative selection	6924906
38477933	38477956	3	+	27260156	G402	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.141031015227981	[285]	[441,309,331,203]	-2	hSpCas9	negative selection	6924907
38478237	38478260	3	-	27260156	L33	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.43887367599829386	[20]	[3,22,13,31]	8	hSpCas9	negative selection	6981873
38478251	38478274	3	+	27260156	L33	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.36720572785094835	[523]	[600,275,545,563]	7	hSpCas9	negative selection	6981874
38454315	38454338	3	+	27260156	L33	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.03463910334155684	[700]	[739,275,445,747]	0	hSpCas9	negative selection	6981875
38454352	38454375	3	-	27260156	L33	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.10817588661160349	[269]	[282,103,231,258]	2	hSpCas9	negative selection	7046156
38477891	38477914	3	-	27260156	L33	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.21767002115113754	[336]	[290,105,219,259]	-5	hSpCas9	negative selection	7046157
38477933	38477956	3	+	27260156	L33	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.23705037647142235	[285]	[201,90,160,290]	-5	hSpCas9	negative selection	7046158
38478237	38478260	3	-	27260156	K562	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.24549594904132022	[20]	[39,19,10,18]	3	hSpCas9	negative selection	7103124
38478251	38478274	3	+	27260156	K562	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.27494796743355704	[523]	[399,547,684,596]	3	hSpCas9	negative selection	7103125
38454315	38454338	3	+	27260156	K562	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.22131895925817924	[700]	[1077,754,461,642]	2	hSpCas9	negative selection	7103126
38454352	38454375	3	-	27260156	K562	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.5632940134311453	[269]	[242,125,105,175]	-6	hSpCas9	negative selection	7167407
38477891	38477914	3	-	27260156	K562	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.02950862420680439	[336]	[223,332,177,460]	0	hSpCas9	negative selection	7167408
38477933	38477956	3	+	27260156	K562	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	1.095898327917517	[285]	[570,702,621,309]	9	hSpCas9	negative selection	7167409
38478237	38478260	3	-	27260156	HT29	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.4457828302118063	[20]	[52,8,67,10]	8	hSpCas9	negative selection	7224375
38478251	38478274	3	+	27260156	HT29	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.2978209141679346	[523]	[853,774,905,616]	6	hSpCas9	negative selection	7224376
38454315	38454338	3	+	27260156	HT29	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.19272302614607362	[700]	[1040,1177,1002,720]	4	hSpCas9	negative selection	7224377
38454352	38454375	3	-	27260156	HT29	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.09949714223359751	[269]	[426,386,409,206]	2	hSpCas9	negative selection	7288658
38477891	38477914	3	-	27260156	HT29	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.1886762306566429	[336]	[567,340,465,483]	3	hSpCas9	negative selection	7288659
38477933	38477956	3	+	27260156	HT29	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.07037627524845014	[285]	[392,311,215,395]	-1	hSpCas9	negative selection	7288660
38478237	38478260	3	-	27260156	MHHES1	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.18352396054752784	[20]	[24,7,37,12]	-3	hSpCas9	negative selection	7345626
38478251	38478274	3	+	27260156	MHHES1	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.5416820925266126	[523]	[848,969,1108,568]	8	hSpCas9	negative selection	7345627
38454315	38454338	3	+	27260156	MHHES1	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.11201239740742641	[700]	[1205,827,851,605]	2	hSpCas9	negative selection	7345628
38454352	38454375	3	-	27260156	MHHES1	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.0293046218094144	[269]	[431,259,177,320]	0	hSpCas9	negative selection	7409909
38477891	38477914	3	-	27260156	MHHES1	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.2403504158456032	[336]	[505,453,421,415]	4	hSpCas9	negative selection	7409910
38477933	38477956	3	+	27260156	MHHES1	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.42738436997533513	[285]	[430,439,570,310]	7	hSpCas9	negative selection	7409911
38478237	38478260	3	-	27260156	MEWO	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.3296782403761691	[20]	[44,24,7]	7	hSpCas9	negative selection	7466877
38478251	38478274	3	+	27260156	MEWO	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.3483763788073759	[523]	[573,529,758]	7	hSpCas9	negative selection	7466878
38454315	38454338	3	+	27260156	MEWO	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.18198439219777607	[700]	[917,650,696]	4	hSpCas9	negative selection	7466879
38454352	38454375	3	-	27260156	MEWO	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.011384985976576445	[269]	[364,240,167]	0	hSpCas9	negative selection	7531160
38477891	38477914	3	-	27260156	MEWO	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.1389091832771222	[336]	[347,267,254]	-3	hSpCas9	negative selection	7531161
38477933	38477956	3	+	27260156	MEWO	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.08145647677178613	[285]	[278,180,303]	-2	hSpCas9	negative selection	7531162
38478237	38478260	3	-	27260156	LNCAPCLONEFGC	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.9396425926395189	[20]	[12,34,39,58]	9	hSpCas9	negative selection	7588128
38478251	38478274	3	+	27260156	LNCAPCLONEFGC	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.4559596426529486	[523]	[605,716,593,674]	7	hSpCas9	negative selection	7588129
38454315	38454338	3	+	27260156	LNCAPCLONEFGC	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.13016405862992242	[700]	[766,452,957,654]	2	hSpCas9	negative selection	7588130
38454352	38454375	3	-	27260156	LNCAPCLONEFGC	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.12156016684624749	[269]	[128,221,189,354]	-2	hSpCas9	negative selection	7652411
38477891	38477914	3	-	27260156	LNCAPCLONEFGC	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.7726163591637496	[336]	[382,796,526,363]	9	hSpCas9	negative selection	7652412
38477933	38477956	3	+	27260156	LNCAPCLONEFGC	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.2861582685204841	[285]	[280,329,435,233]	4	hSpCas9	negative selection	7652413
38478237	38478260	3	-	27260156	PANC0327	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.4272066672192496	[20]	[37,19,5,37]	6	hSpCas9	negative selection	7709379
38478251	38478274	3	+	27260156	PANC0327	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.5860934865618974	[523]	[601,815,791,561]	8	hSpCas9	negative selection	7709380
38454315	38454338	3	+	27260156	PANC0327	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.14834275879901027	[700]	[796,749,479,733]	2	hSpCas9	negative selection	7709381
38454352	38454375	3	-	27260156	PANC0327	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.665817628513822	[269]	[457,458,284,315]	8	hSpCas9	negative selection	7773662
38477891	38477914	3	-	27260156	PANC0327	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.18153976477261446	[336]	[210,265,204,368]	-3	hSpCas9	negative selection	7773663
38477933	38477956	3	+	27260156	PANC0327	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.08302286210403043	[285]	[208,361,198,170]	-1	hSpCas9	negative selection	7773664
38478237	38478260	3	-	27260156	NCIH2009	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.7272078987089374	[20]	[79,34,173]	9	hSpCas9	negative selection	7830630
38478251	38478274	3	+	27260156	NCIH2009	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.9727124652118979	[523]	[1860,1423,1106]	9	hSpCas9	negative selection	7830631
38454315	38454338	3	+	27260156	NCIH2009	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.3491611518289759	[700]	[1356,1537,861]	5	hSpCas9	negative selection	7830632
38454352	38454375	3	-	27260156	NCIH2009	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.02176479103017981	[269]	[516,308,317]	0	hSpCas9	negative selection	7894913
38477891	38477914	3	-	27260156	NCIH2009	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.41798953639058695	[336]	[449,670,728]	6	hSpCas9	negative selection	7894914
38477933	38477956	3	+	27260156	NCIH2009	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.03232495232833532	[285]	[426,510,288]	0	hSpCas9	negative selection	7894915
38478237	38478260	3	-	27260156	NCIH1373	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.10417773107394623	[20]	[31,9,14,8]	-1	hSpCas9	negative selection	7951881
38478251	38478274	3	+	27260156	NCIH1373	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	1.0351863019716872	[523]	[995,803,1369,439]	9	hSpCas9	negative selection	7951882
38454315	38454338	3	+	27260156	NCIH1373	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.04033799406025551	[700]	[916,706,533,294]	0	hSpCas9	negative selection	7951883
38454352	38454375	3	-	27260156	NCIH1373	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.15258349992402975	[269]	[203,351,154,95]	-1	hSpCas9	negative selection	8016164
38477891	38477914	3	-	27260156	NCIH1373	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.41868940820404565	[336]	[586,402,445,160]	4	hSpCas9	negative selection	8016165
38477933	38477956	3	+	27260156	NCIH1373	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.09615764363072787	[285]	[305,428,322,76]	1	hSpCas9	negative selection	8016166
38478237	38478260	3	-	27260156	PATU8902	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.3512146125530382	[20]	[96,82,14,123]	9	hSpCas9	negative selection	8073132
38478251	38478274	3	+	27260156	PATU8902	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.7809630149310833	[523]	[1424,1065,1175,1369]	8	hSpCas9	negative selection	8073133
38454315	38454338	3	+	27260156	PATU8902	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.6387330437511243	[700]	[1863,2391,1099,723]	6	hSpCas9	negative selection	8073134
38454352	38454375	3	-	27260156	PATU8902	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.52391336633025	[269]	[225,141,404,229]	-5	hSpCas9	negative selection	8137415
38477891	38477914	3	-	27260156	PATU8902	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.355071762176259	[336]	[550,401,809,575]	3	hSpCas9	negative selection	8137416
38477933	38477956	3	+	27260156	PATU8902	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.9006081615604391	[285]	[115,272,111,400]	-7	hSpCas9	negative selection	8137417
38478237	38478260	3	-	27260156	PANC1	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.26461564369001866	[20]	[0,36,0,23]	-4	hSpCas9	negative selection	8194383
38478251	38478274	3	+	27260156	PANC1	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.301090207294889	[523]	[505,644,554,526]	5	hSpCas9	negative selection	8194384
38454315	38454338	3	+	27260156	PANC1	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.10719965187333269	[700]	[728,884,644,410]	1	hSpCas9	negative selection	8194385
38454352	38454375	3	-	27260156	PANC1	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.06413303983563534	[269]	[201,365,97,242]	-1	hSpCas9	negative selection	8258666
38477891	38477914	3	-	27260156	PANC1	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.04418140577696855	[336]	[228,376,397,216]	0	hSpCas9	negative selection	8258667
38477933	38477956	3	+	27260156	PANC1	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.12736431833695705	[285]	[137,368,272,305]	2	hSpCas9	negative selection	8258668
38478237	38478260	3	-	27260156	PANC0813	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	1.2042814782830402	[20]	[60,41,89,35]	9	hSpCas9	negative selection	8315634
38478251	38478274	3	+	27260156	PANC0813	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.48227632608266086	[523]	[1010,891,738,811]	7	hSpCas9	negative selection	8315635
38454315	38454338	3	+	27260156	PANC0813	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.19267327235908493	[700]	[982,1114,872,802]	3	hSpCas9	negative selection	8315636
38454352	38454375	3	-	27260156	PANC0813	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.2909288427250656	[269]	[263,284,300,190]	-4	hSpCas9	negative selection	8379917
38477891	38477914	3	-	27260156	PANC0813	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.4397730061755599	[336]	[514,408,639,578]	7	hSpCas9	negative selection	8379918
38477933	38477956	3	+	27260156	PANC0813	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.023900838925026036	[285]	[446,310,336,241]	0	hSpCas9	negative selection	8379919
38478237	38478260	3	-	27260156	RDES	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.3917211518052319	[20]	[42,6,21,56]	6	hSpCas9	negative selection	8436885
38478251	38478274	3	+	27260156	RDES	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.551710657988195	[523]	[729,935,873,1012]	8	hSpCas9	negative selection	8436886
38454315	38454338	3	+	27260156	RDES	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.39422229049683843	[700]	[902,887,1363,1121]	6	hSpCas9	negative selection	8436887
38454352	38454375	3	-	27260156	RDES	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.2500390729991987	[269]	[332,373,457,299]	4	hSpCas9	negative selection	8501168
38477891	38477914	3	-	27260156	RDES	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.45970487762340717	[336]	[358,466,748,605]	7	hSpCas9	negative selection	8501169
38477933	38477956	3	+	27260156	RDES	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.23491257525317671	[285]	[267,418,340,555]	4	hSpCas9	negative selection	8501170
38478237	38478260	3	-	27260156	PC3	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.8737540557995493	[20]	[33,49,13,41]	9	hSpCas9	negative selection	8558136
38478251	38478274	3	+	27260156	PC3	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.34604771216232005	[523]	[420,747,861,739]	7	hSpCas9	negative selection	8558137
38454315	38454338	3	+	27260156	PC3	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.25680648142304563	[700]	[439,712,1306,1189]	5	hSpCas9	negative selection	8558138
38454352	38454375	3	-	27260156	PC3	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.3334728347009453	[269]	[308,247,600,269]	7	hSpCas9	negative selection	8622419
38477891	38477914	3	-	27260156	PC3	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.28756997087688496	[336]	[222,345,744,511]	6	hSpCas9	negative selection	8622420
38477933	38477956	3	+	27260156	PC3	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.07901596482022377	[285]	[229,300,572,197]	1	hSpCas9	negative selection	8622421
38478237	38478260	3	-	27260156	PATU8988T	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.6410480624508699	[20]	[12,7,39,65]	9	hSpCas9	negative selection	8679387
38478251	38478274	3	+	27260156	PATU8988T	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.3889284723275111	[523]	[554,819,629,661]	6	hSpCas9	negative selection	8679388
38454315	38454338	3	+	27260156	PATU8988T	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.16227709592730843	[700]	[693,909,637,809]	3	hSpCas9	negative selection	8679389
38454352	38454375	3	-	27260156	PATU8988T	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.019177487446862318	[269]	[302,254,176,298]	0	hSpCas9	negative selection	8743670
38477891	38477914	3	-	27260156	PATU8988T	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.06430863308142465	[336]	[321,394,252,281]	-1	hSpCas9	negative selection	8743671
38477933	38477956	3	+	27260156	PATU8988T	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.13173535096141908	[285]	[228,284,275,218]	-2	hSpCas9	negative selection	8743672
38478237	38478260	3	-	27260156	T47D	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.31358010772002753	[20]	[31,26,29,32]	6	hSpCas9	negative selection	8800638
38478251	38478274	3	+	27260156	T47D	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.29186410505849436	[523]	[789,685,693,827]	6	hSpCas9	negative selection	8800639
38454315	38454338	3	+	27260156	T47D	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.09281048766374767	[700]	[840,903,812,924]	2	hSpCas9	negative selection	8800640
38454352	38454375	3	-	27260156	T47D	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.004802818021820698	[269]	[340,198,357,366]	0	hSpCas9	negative selection	8864921
38477891	38477914	3	-	27260156	T47D	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.1285261072314347	[336]	[416,426,432,439]	2	hSpCas9	negative selection	8864922
38477933	38477956	3	+	27260156	T47D	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.2389425587886384	[285]	[450,326,436,361]	5	hSpCas9	negative selection	8864923
38478237	38478260	3	-	27260156	SU8686	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.21724243723452474	[20]	[10,8,25,59]	3	hSpCas9	negative selection	8921889
38478251	38478274	3	+	27260156	SU8686	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.6621246863625401	[523]	[675,629,961,1105]	9	hSpCas9	negative selection	8921890
38454315	38454338	3	+	27260156	SU8686	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.43543263439146074	[700]	[761,835,1002,1234]	7	hSpCas9	negative selection	8921891
38454352	38454375	3	-	27260156	SU8686	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.0483885197047923	[269]	[211,260,293,361]	0	hSpCas9	negative selection	8986172
38477891	38477914	3	-	27260156	SU8686	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.20276409708381687	[336]	[341,329,370,526]	3	hSpCas9	negative selection	8986173
38477933	38477956	3	+	27260156	SU8686	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.1788735820750843	[285]	[208,247,498,358]	3	hSpCas9	negative selection	8986174
38478237	38478260	3	-	27260156	SKES1	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.9072297123036539	[20]	[67,53,32,10]	9	hSpCas9	negative selection	9043140
38478251	38478274	3	+	27260156	SKES1	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.47663584122514574	[523]	[870,706,660,685]	8	hSpCas9	negative selection	9043141
38454315	38454338	3	+	27260156	SKES1	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.28827522352956936	[700]	[1105,746,728,848]	6	hSpCas9	negative selection	9043142
38454352	38454375	3	-	27260156	SKES1	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.36567926792158123	[269]	[465,389,235,318]	7	hSpCas9	negative selection	9107423
38477891	38477914	3	-	27260156	SKES1	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.10234140403713426	[336]	[362,428,274,379]	2	hSpCas9	negative selection	9107424
38477933	38477956	3	+	27260156	SKES1	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.04054376310542285	[285]	[241,349,353,230]	0	hSpCas9	negative selection	9107425
38478237	38478260	3	-	27260156	TOV112D	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.34434646944684744	[20]	[29,0,16,51]	6	hSpCas9	negative selection	9164391
38478251	38478274	3	+	27260156	TOV112D	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.6821536268183344	[523]	[903,788,1038,632]	9	hSpCas9	negative selection	9164392
38454315	38454338	3	+	27260156	TOV112D	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.20118050972857437	[700]	[669,841,858,851]	4	hSpCas9	negative selection	9164393
38454352	38454375	3	-	27260156	TOV112D	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.07334588845348722	[269]	[260,478,285,160]	1	hSpCas9	negative selection	9228674
38477891	38477914	3	-	27260156	TOV112D	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.15235043268172027	[336]	[362,510,309,348]	3	hSpCas9	negative selection	9228675
38477933	38477956	3	+	27260156	TOV112D	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	-0.04781970297204985	[285]	[205,318,299,286]	-1	hSpCas9	negative selection	9228676
38478237	38478260	3	-	27260156	TC71	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.5374760271227887	[20]	[25,8,40,55]	9	hSpCas9	negative selection	9285642
38478251	38478274	3	+	27260156	TC71	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.2286493984457414	[523]	[518,665,702,751]	5	hSpCas9	negative selection	9285643
38454315	38454338	3	+	27260156	TC71	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.11277110220814479	[700]	[719,790,739,1015]	3	hSpCas9	negative selection	9285644
38454352	38454375	3	-	27260156	TC71	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	0.07108825647686601	[269]	[299,372,273,267]	1	hSpCas9	negative selection	9349925
38477891	38477914	3	-	27260156	TC71	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.06425784678411872	[336]	[344,332,363,338]	-2	hSpCas9	negative selection	9349926
38477933	38477956	3	+	27260156	TC71	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.19868025080703666	[285]	[381,343,233,456]	5	hSpCas9	negative selection	9349927
38478237	38478260	3	-	27260156	TC32	viability	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.23441279934138137	[20]	[17,0,37,18]	-4	hSpCas9	negative selection	9406893
38478251	38478274	3	+	27260156	TC32	viability	CGGCATCGCAAGCCCCCCTACGG	ACVR2B	ENSG00000114739	0.306189110889427	[523]	[639,372,779,728]	5	hSpCas9	negative selection	9406894
38454315	38454338	3	+	27260156	TC32	viability	CGCGGAACATGACGGCGCCCTGG	ACVR2B	ENSG00000114739	0.29895128414186867	[700]	[632,691,946,1023]	5	hSpCas9	negative selection	9406895
38454352	38454375	3	-	27260156	TC32	viability	CGGCGCACAGCGATCCCCAGAGG	ACVR2B	ENSG00000114739	-0.2909959542406755	[269]	[186,224,211,186]	-5	hSpCas9	negative selection	9471176
38477891	38477914	3	-	27260156	TC32	viability	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.6483710163935137	[336]	[410,387,664,577]	9	hSpCas9	negative selection	9471177
38477933	38477956	3	+	27260156	TC32	viability	ACGCTTCACTCATTTGCCAGAGG	ACVR2B	ENSG00000114739	0.26828702308607316	[285]	[357,162,427,406]	5	hSpCas9	negative selection	9471178
38477419	38477442	3	-	27869803	HPAFII	viability after 27 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	2.5032228331160282	[79]	[364,132,NaN]	9	hSpCas9	negative selection	9584609
38477891	38477914	3	-	27869803	HPAFII	viability after 27 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.20051561611853325	[213]	[140,61,NaN]	-1	hSpCas9	negative selection	9584610
38478237	38478260	3	-	27869803	HPAFII	viability after 27 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.9468886635404372	[16]	[2,5,NaN]	-6	hSpCas9	negative selection	9584611
38479250	38479273	3	+	27869803	HPAFII	viability after 27 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.5661040508063879	[410]	[434,223,NaN]	4	hSpCas9	negative selection	9584612
38479791	38479814	3	-	27869803	HPAFII	viability after 27 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.12098934095394331	[172]	[117,54,NaN]	-1	hSpCas9	negative selection	9584613
38481415	38481438	3	+	27869803	HPAFII	viability after 27 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.43014455338643	[362]	[222,756,NaN]	9	hSpCas9	negative selection	9584614
38477419	38477442	3	-	27869803	HPAFII	viability after 15 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	1.3356840920523303	[79]	[446,73,NaN]	9	hSpCas9	negative selection	9667058
38477891	38477914	3	-	27869803	HPAFII	viability after 15 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.5588352520887083	[213]	[479,250,NaN]	6	hSpCas9	negative selection	9667059
38478237	38478260	3	-	27869803	HPAFII	viability after 15 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-1.4012987756579873	[16]	[9,4,NaN]	-8	hSpCas9	negative selection	9667060
38479250	38479273	3	+	27869803	HPAFII	viability after 15 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.7613969518791608	[410]	[1061,553,NaN]	8	hSpCas9	negative selection	9667061
38479791	38479814	3	-	27869803	HPAFII	viability after 15 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.15387595609993554	[172]	[184,155,NaN]	-2	hSpCas9	negative selection	9667062
38481415	38481438	3	+	27869803	HPAFII	viability after 15 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.8046837984011972	[362]	[604,728,NaN]	8	hSpCas9	negative selection	9667063
38477419	38477442	3	-	27869803	ASPC1	viability after 36 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	1.2709788557944086	[138]	[120,149,86]	9	hSpCas9	negative selection	9749507
38477891	38477914	3	-	27869803	ASPC1	viability after 36 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.9892954164219312	[740]	[377,713,443]	8	hSpCas9	negative selection	9749508
38478237	38478260	3	-	27869803	ASPC1	viability after 36 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	0.09058925172478727	[22]	[10,11,3]	0	hSpCas9	negative selection	9749509
38479250	38479273	3	+	27869803	ASPC1	viability after 36 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	-0.5370955599168192	[1027]	[369,203,192]	-5	hSpCas9	negative selection	9749510
38479791	38479814	3	-	27869803	ASPC1	viability after 36 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.19927519707222796	[553]	[162,264,226]	2	hSpCas9	negative selection	9749511
38481415	38481438	3	+	27869803	ASPC1	viability after 36 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.5966876487122652	[755]	[681,420,178]	6	hSpCas9	negative selection	9749512
38477419	38477442	3	-	27869803	PATU8988S	viability after 35 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.13248617782349004	[170]	[72,77,NaN]	1	hSpCas9	negative selection	9831956
38477891	38477914	3	-	27869803	PATU8988S	viability after 35 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.06926700510266048	[897]	[360,397,NaN]	0	hSpCas9	negative selection	9831957
38478237	38478260	3	-	27869803	PATU8988S	viability after 35 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.414540841719754	[42]	[9,15,NaN]	-4	hSpCas9	negative selection	9831958
38479250	38479273	3	+	27869803	PATU8988S	viability after 35 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.552844843754371	[1015]	[502,697,NaN]	6	hSpCas9	negative selection	9831959
38479791	38479814	3	-	27869803	PATU8988S	viability after 35 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.39543532346190924	[542]	[355,218,NaN]	4	hSpCas9	negative selection	9831960
38481415	38481438	3	+	27869803	PATU8988S	viability after 35 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	-0.09502389813975548	[714]	[317,220,NaN]	-1	hSpCas9	negative selection	9831961
38477419	38477442	3	-	27869803	PATU8988S	viability after 31 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	0.4194976779142152	[170]	[66,121,NaN]	5	hSpCas9	negative selection	9914405
38477891	38477914	3	-	27869803	PATU8988S	viability after 31 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.006075625602172341	[897]	[275,465,NaN]	0	hSpCas9	negative selection	9914406
38478237	38478260	3	-	27869803	PATU8988S	viability after 31 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-1.41275719441757	[42]	[5,6,NaN]	-8	hSpCas9	negative selection	9914407
38479250	38479273	3	+	27869803	PATU8988S	viability after 31 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.5519088523198182	[1015]	[402,836,NaN]	6	hSpCas9	negative selection	9914408
38479791	38479814	3	-	27869803	PATU8988S	viability after 31 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	0.5130265444035282	[542]	[209,434,NaN]	6	hSpCas9	negative selection	9914409
38481415	38481438	3	+	27869803	PATU8988S	viability after 31 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	0.04730803074422607	[714]	[320,260,NaN]	0	hSpCas9	negative selection	9914410
38477419	38477442	3	-	27869803	HPAFII	viability after 35 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	3.0034910297288997	[79]	[479,149,NaN]	9	hSpCas9	negative selection	9996854
38477891	38477914	3	-	27869803	HPAFII	viability after 35 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	0.2029803766584916	[213]	[119,129,NaN]	1	hSpCas9	negative selection	9996855
38478237	38478260	3	-	27869803	HPAFII	viability after 35 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.41152925647382066	[16]	[5,6,NaN]	-3	hSpCas9	negative selection	9996856
38479250	38479273	3	+	27869803	HPAFII	viability after 35 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	1.2569186632017244	[410]	[643,331,NaN]	8	hSpCas9	negative selection	9996857
38479791	38479814	3	-	27869803	HPAFII	viability after 35 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.47408355493616394	[172]	[47,79,NaN]	-3	hSpCas9	negative selection	9996858
38481415	38481438	3	+	27869803	HPAFII	viability after 35 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.6764603288804367	[362]	[204,1017,NaN]	9	hSpCas9	negative selection	9996859
38477419	38477442	3	-	27869803	HPAFII	viability after 31 days	GGTGCCAGAGCTGTTGCGCCAGG	ACVR2B	ENSG00000114739	2.0016923154149806	[79]	[219,135,NaN]	9	hSpCas9	negative selection	10079303
38477891	38477914	3	-	27869803	HPAFII	viability after 31 days	CACAGCAGCAGAAGTACACCTGG	ACVR2B	ENSG00000114739	-0.4115558278551827	[213]	[107,70,NaN]	-3	hSpCas9	negative selection	10079304
38478237	38478260	3	-	27869803	HPAFII	viability after 31 days	GCGATGCCGGTACATCCAAAAGG	ACVR2B	ENSG00000114739	-0.5489036085358263	[16]	[6,5,NaN]	-4	hSpCas9	negative selection	10079305
38479250	38479273	3	+	27869803	HPAFII	viability after 31 days	CATCACGGCCTTCCATGACAAGG	ACVR2B	ENSG00000114739	0.7339967000915046	[410]	[464,294,NaN]	5	hSpCas9	negative selection	10079306
38479791	38479814	3	-	27869803	HPAFII	viability after 31 days	ACGGCTTGTGGCCCTCGCCACGG	ACVR2B	ENSG00000114739	-0.4580560529715588	[172]	[96,41,NaN]	-3	hSpCas9	negative selection	10079307
38481415	38481438	3	+	27869803	HPAFII	viability after 31 days	TTGGCTGTTCGATTTGAGCCAGG	ACVR2B	ENSG00000114739	1.770370146743133	[362]	[325,1096,NaN]	9	hSpCas9	negative selection	10079308
38477890	38477913	3	-	28162770	P31FUJ	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.12588700049786672	[558]	[601]	-1	hSpCas9	negative selection	10106642
38478390	38478413	3	-	28162770	P31FUJ	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.3871303508056725	[275]	[247]	-3	hSpCas9	negative selection	10106643
38479120	38479143	3	+	28162770	P31FUJ	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.0228235201048288	[422]	[504]	0	hSpCas9	negative selection	10106644
38454343	38454366	3	-	28162770	P31FUJ	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	0.7057972509214779	[71]	[137]	7	hSpCas9	negative selection	10106645
38477293	38477316	3	+	28162770	P31FUJ	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-6.255170017442833	[64]	[0]	-9	hSpCas9	negative selection	10106646
38477372	38477395	3	+	28162770	P31FUJ	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	1.303250695825831	[39]	[115]	9	hSpCas9	negative selection	10106647
38478168	38478191	3	-	28162770	P31FUJ	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.13916657297257928	[135]	[175]	1	hSpCas9	negative selection	10106648
38478220	38478243	3	-	28162770	P31FUJ	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	1.8440133926364526	[31]	[134]	9	hSpCas9	negative selection	10106649
38478267	38478290	3	-	28162770	P31FUJ	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.020771872170349148	[509]	[607]	0	hSpCas9	negative selection	10106650
38478377	38478400	3	-	28162770	P31FUJ	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-2.37964359274365	[340]	[76]	-8	hSpCas9	negative selection	10106651
38477890	38477913	3	-	28162770	TF1	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[492]	1	hSpCas9	negative selection	10276008
38478390	38478413	3	-	28162770	TF1	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[350]	1	hSpCas9	negative selection	10276009
38479120	38479143	3	+	28162770	TF1	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[871]	1	hSpCas9	negative selection	10276010
38454343	38454366	3	-	28162770	TF1	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10276011
38477293	38477316	3	+	28162770	TF1	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10276012
38477372	38477395	3	+	28162770	TF1	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10276013
38478168	38478191	3	-	28162770	TF1	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10276014
38478220	38478243	3	-	28162770	TF1	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10276015
38478267	38478290	3	-	28162770	TF1	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[491]	1	hSpCas9	negative selection	10276016
38478377	38478400	3	-	28162770	TF1	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10276017
38477890	38477913	3	-	28162770	SKM1	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.06511540973253926	[186]	[315]	0	hSpCas9	negative selection	10445374
38478390	38478413	3	-	28162770	SKM1	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	0.4675049191729794	[44]	[109]	4	hSpCas9	negative selection	10445375
38479120	38479143	3	+	28162770	SKM1	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.2934755193979307	[95]	[207]	3	hSpCas9	negative selection	10445376
38454343	38454366	3	-	28162770	SKM1	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.8923910259134034	[20]	[19]	-6	hSpCas9	negative selection	10445377
38477293	38477316	3	+	28162770	SKM1	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.909464539272345	[16]	[0]	-9	hSpCas9	negative selection	10445378
38477372	38477395	3	+	28162770	SKM1	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.4675049191729792	[17]	[43]	4	hSpCas9	negative selection	10445379
38478168	38478191	3	-	28162770	SKM1	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	1.2654611432283338	[15]	[67]	9	hSpCas9	negative selection	10445380
38478220	38478243	3	-	28162770	SKM1	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	0.8409633147004237	[17]	[56]	7	hSpCas9	negative selection	10445381
38478267	38478290	3	-	28162770	SKM1	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.1122575725908237	[106]	[174]	-1	hSpCas9	negative selection	10445382
38478377	38478400	3	-	28162770	SKM1	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.8220016980220055	[87]	[43]	-8	hSpCas9	negative selection	10445383
38477890	38477913	3	-	28162770	SKM1	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.06511540973253926	[186]	[315]	0	hSpCas9	negative selection	10614740
38478390	38478413	3	-	28162770	SKM1	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	0.4675049191729794	[44]	[109]	4	hSpCas9	negative selection	10614741
38479120	38479143	3	+	28162770	SKM1	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.2934755193979307	[95]	[207]	3	hSpCas9	negative selection	10614742
38454343	38454366	3	-	28162770	SKM1	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.8923910259134034	[20]	[19]	-6	hSpCas9	negative selection	10614743
38477293	38477316	3	+	28162770	SKM1	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.909464539272345	[16]	[0]	-9	hSpCas9	negative selection	10614744
38477372	38477395	3	+	28162770	SKM1	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.4675049191729792	[17]	[43]	4	hSpCas9	negative selection	10614745
38478168	38478191	3	-	28162770	SKM1	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	1.2654611432283338	[15]	[67]	9	hSpCas9	negative selection	10614746
38478220	38478243	3	-	28162770	SKM1	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	0.8409633147004237	[17]	[56]	7	hSpCas9	negative selection	10614747
38478267	38478290	3	-	28162770	SKM1	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.1122575725908237	[106]	[174]	-1	hSpCas9	negative selection	10614748
38478377	38478400	3	-	28162770	SKM1	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.8220016980220055	[87]	[43]	-8	hSpCas9	negative selection	10614749
38477890	38477913	3	-	28162770	PL21	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.37079196408965975	[660]	[371]	3	hSpCas9	negative selection	10784106
38478390	38478413	3	-	28162770	PL21	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	0.20953831249156957	[152]	[76]	1	hSpCas9	negative selection	10784107
38479120	38479143	3	+	28162770	PL21	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.2328058034096423	[392]	[200]	2	hSpCas9	negative selection	10784108
38454343	38454366	3	-	28162770	PL21	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.3473481808131731	[75]	[25]	-2	hSpCas9	negative selection	10784109
38477293	38477316	3	+	28162770	PL21	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.354449237188318	[46]	[0]	-9	hSpCas9	negative selection	10784110
38477372	38477395	3	+	28162770	PL21	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	-0.5572900822366016	[70]	[20]	-4	hSpCas9	negative selection	10784111
38478168	38478191	3	-	28162770	PL21	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.729248880476959	[78]	[56]	6	hSpCas9	negative selection	10784112
38478220	38478243	3	-	28162770	PL21	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-0.5368259796768862	[29]	[8]	-4	hSpCas9	negative selection	10784113
38478267	38478290	3	-	28162770	PL21	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.6588697037955615	[373]	[256]	5	hSpCas9	negative selection	10784114
38478377	38478400	3	-	28162770	PL21	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-0.3731881857484328	[246]	[82]	-3	hSpCas9	negative selection	10784115
38477890	38477913	3	-	28162770	P31FUJ	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.12588700049786672	[558]	[601]	-1	hSpCas9	negative selection	10953472
38478390	38478413	3	-	28162770	P31FUJ	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.3871303508056725	[275]	[247]	-3	hSpCas9	negative selection	10953473
38479120	38479143	3	+	28162770	P31FUJ	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.0228235201048288	[422]	[504]	0	hSpCas9	negative selection	10953474
38454343	38454366	3	-	28162770	P31FUJ	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	0.7057972509214779	[71]	[137]	7	hSpCas9	negative selection	10953475
38477293	38477316	3	+	28162770	P31FUJ	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-6.255170017442833	[64]	[0]	-9	hSpCas9	negative selection	10953476
38477372	38477395	3	+	28162770	P31FUJ	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	1.303250695825831	[39]	[115]	9	hSpCas9	negative selection	10953477
38478168	38478191	3	-	28162770	P31FUJ	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.13916657297257928	[135]	[175]	1	hSpCas9	negative selection	10953478
38478220	38478243	3	-	28162770	P31FUJ	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	1.8440133926364526	[31]	[134]	9	hSpCas9	negative selection	10953479
38478267	38478290	3	-	28162770	P31FUJ	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.020771872170349148	[509]	[607]	0	hSpCas9	negative selection	10953480
38478377	38478400	3	-	28162770	P31FUJ	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-2.37964359274365	[340]	[76]	-8	hSpCas9	negative selection	10953481
38477890	38477913	3	-	28162770	OCIAML5	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	1.2134621786596083	[268]	[1125]	9	hSpCas9	negative selection	11122838
38478390	38478413	3	-	28162770	OCIAML5	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.3926349522266997	[119]	[164]	-3	hSpCas9	negative selection	11122839
38479120	38479143	3	+	28162770	OCIAML5	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.41642226506190494	[197]	[476]	3	hSpCas9	negative selection	11122840
38454343	38454366	3	-	28162770	OCIAML5	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.009607847850476858	[28]	[51]	0	hSpCas9	negative selection	11122841
38477293	38477316	3	+	28162770	OCIAML5	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.659421492921601	[13]	[0]	-9	hSpCas9	negative selection	11122842
38477372	38477395	3	+	28162770	OCIAML5	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	3.440715178363849	[4]	[97]	9	hSpCas9	negative selection	11122843
38478168	38478191	3	-	28162770	OCIAML5	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.8901356716683563	[54]	[183]	7	hSpCas9	negative selection	11122844
38478220	38478243	3	-	28162770	OCIAML5	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-1.1569211523924177	[41]	[33]	-6	hSpCas9	negative selection	11122845
38478267	38478290	3	-	28162770	OCIAML5	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.2746052326244315	[315]	[689]	2	hSpCas9	negative selection	11122846
38478377	38478400	3	-	28162770	OCIAML5	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.876728625098266	[176]	[86]	-7	hSpCas9	negative selection	11122847
38477890	38477913	3	-	28162770	EOL1	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.3724244972172932	[1150]	[784]	3	hSpCas9	negative selection	11292204
38478390	38478413	3	-	28162770	EOL1	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.042029226892015076	[255]	[130]	0	hSpCas9	negative selection	11292205
38479120	38479143	3	+	28162770	EOL1	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.8720068516615636	[726]	[700]	7	hSpCas9	negative selection	11292206
38454343	38454366	3	-	28162770	EOL1	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	1.137277095556263	[106]	[123]	8	hSpCas9	negative selection	11292207
38477293	38477316	3	+	28162770	EOL1	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.090402569895437	[96]	[2]	-9	hSpCas9	negative selection	11292208
38477372	38477395	3	+	28162770	EOL1	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.49014494742475967	[99]	[73]	4	hSpCas9	negative selection	11292209
38478168	38478191	3	-	28162770	EOL1	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	-0.3788443718794001	[115]	[46]	-3	hSpCas9	negative selection	11292210
38478220	38478243	3	-	28162770	EOL1	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	0.9859483162346776	[45]	[47]	8	hSpCas9	negative selection	11292211
38478267	38478290	3	-	28162770	EOL1	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.2884459517636637	[560]	[241]	-2	hSpCas9	negative selection	11292212
38478377	38478400	3	-	28162770	EOL1	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-2.5779525689586484	[305]	[26]	-9	hSpCas9	negative selection	11292213
38477890	38477913	3	-	28162770	MOLM13	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.5753657488898818	[917]	[988]	4	hSpCas9	negative selection	11461570
38478390	38478413	3	-	28162770	MOLM13	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	0.48310247549108576	[282]	[285]	3	hSpCas9	negative selection	11461571
38479120	38479143	3	+	28162770	MOLM13	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.34322680826868845	[603]	[553]	2	hSpCas9	negative selection	11461572
38454343	38454366	3	-	28162770	MOLM13	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	0.6952998776476513	[81]	[95]	5	hSpCas9	negative selection	11461573
38477293	38477316	3	+	28162770	MOLM13	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-5.509390541955338	[62]	[0]	-9	hSpCas9	negative selection	11461574
38477372	38477395	3	+	28162770	MOLM13	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.9785045408056537	[72]	[103]	7	hSpCas9	negative selection	11461575
38478168	38478191	3	-	28162770	MOLM13	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	2.4220856919314544	[111]	[433]	9	hSpCas9	negative selection	11461576
38478220	38478243	3	-	28162770	MOLM13	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	0.46788938154457904	[40]	[40]	3	hSpCas9	negative selection	11461577
38478267	38478290	3	-	28162770	MOLM13	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.7630650532952933	[675]	[287]	-4	hSpCas9	negative selection	11461578
38478377	38478400	3	-	28162770	MOLM13	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-3.117073119176577	[263]	[21]	-8	hSpCas9	negative selection	11461579
38477890	38477913	3	-	28162770	HEL	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.49171883572512987	[814]	[733]	4	hSpCas9	negative selection	11630936
38478390	38478413	3	-	28162770	HEL	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.8897562488266638	[161]	[55]	-5	hSpCas9	negative selection	11630937
38479120	38479143	3	+	28162770	HEL	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	-0.33627614287030705	[545]	[276]	-2	hSpCas9	negative selection	11630938
38454343	38454366	3	-	28162770	HEL	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.4131144027331608	[78]	[37]	-3	hSpCas9	negative selection	11630939
38477293	38477316	3	+	28162770	HEL	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.5470857268796605	[72]	[1]	-9	hSpCas9	negative selection	11630940
38477372	38477395	3	+	28162770	HEL	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.024301626728112646	[108]	[70]	0	hSpCas9	negative selection	11630941
38478168	38478191	3	-	28162770	HEL	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	-0.20970397958578513	[129]	[71]	-1	hSpCas9	negative selection	11630942
38478220	38478243	3	-	28162770	HEL	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-0.8426879951698849	[41]	[14]	-5	hSpCas9	negative selection	11630943
38478267	38478290	3	-	28162770	HEL	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.11772849069638158	[435]	[302]	0	hSpCas9	negative selection	11630944
38478377	38478400	3	-	28162770	HEL	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.549906245942039	[223]	[48]	-7	hSpCas9	negative selection	11630945
38477890	38477913	3	-	28162770	MV411	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.6803969580588818	[619]	[836]	6	hSpCas9	negative selection	11800302
38478390	38478413	3	-	28162770	MV411	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	0.558037639868625	[178]	[221]	5	hSpCas9	negative selection	11800303
38479120	38479143	3	+	28162770	MV411	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	-0.04861191227898143	[441]	[359]	0	hSpCas9	negative selection	11800304
38454343	38454366	3	-	28162770	MV411	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	0.193998291821315	[54]	[52]	1	hSpCas9	negative selection	11800305
38477293	38477316	3	+	28162770	MV411	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-2.659453044825743	[59]	[7]	-9	hSpCas9	negative selection	11800306
38477372	38477395	3	+	28162770	MV411	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	0.037219843392429786	[58]	[50]	0	hSpCas9	negative selection	11800307
38478168	38478191	3	-	28162770	MV411	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	-1.3375249499383808	[95]	[31]	-7	hSpCas9	negative selection	11800308
38478220	38478243	3	-	28162770	MV411	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-0.8728566829349367	[49]	[22]	-5	hSpCas9	negative selection	11800309
38478267	38478290	3	-	28162770	MV411	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.3493990502266726	[365]	[241]	-3	hSpCas9	negative selection	11800310
38478377	38478400	3	-	28162770	MV411	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-0.9282011018539308	[252]	[111]	-6	hSpCas9	negative selection	11800311
38477890	38477913	3	-	28162770	MONOMAC1	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.785141875853202	[447]	[884]	7	hSpCas9	negative selection	11969668
38478390	38478413	3	-	28162770	MONOMAC1	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.31871540364780615	[135]	[124]	-3	hSpCas9	negative selection	11969669
38479120	38479143	3	+	28162770	MONOMAC1	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.40030937811743494	[231]	[350]	4	hSpCas9	negative selection	11969670
38454343	38454366	3	-	28162770	MONOMAC1	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	1.0721497857558353	[38]	[93]	8	hSpCas9	negative selection	11969671
38477293	38477316	3	+	28162770	MONOMAC1	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-4.5893542698383145	[41]	[1]	-9	hSpCas9	negative selection	11969672
38477372	38477395	3	+	28162770	MONOMAC1	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	2.8659729504662463	[27]	[233]	9	hSpCas9	negative selection	11969673
38478168	38478191	3	-	28162770	MONOMAC1	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	0.6561217646111753	[61]	[111]	6	hSpCas9	negative selection	11969674
38478220	38478243	3	-	28162770	MONOMAC1	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	2.610318074998051	[9]	[69]	9	hSpCas9	negative selection	11969675
38478267	38478290	3	-	28162770	MONOMAC1	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.5311917330252431	[264]	[438]	5	hSpCas9	negative selection	11969676
38478377	38478400	3	-	28162770	MONOMAC1	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-2.0778895817665486	[150]	[40]	-9	hSpCas9	negative selection	11969677
38477890	38477913	3	-	28162770	OCIAML2	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	-0.11164813559885212	[122]	[630]	-1	hSpCas9	negative selection	12139034
38478390	38478413	3	-	28162770	OCIAML2	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	0.27045187739627674	[34]	[233]	2	hSpCas9	negative selection	12139035
38479120	38479143	3	+	28162770	OCIAML2	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	0.3157018462450243	[78]	[544]	3	hSpCas9	negative selection	12139036
38454343	38454366	3	-	28162770	OCIAML2	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.40024049735076295	[9]	[41]	-3	hSpCas9	negative selection	12139037
38477293	38477316	3	+	28162770	OCIAML2	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-6.4706298252421615	[15]	[0]	-9	hSpCas9	negative selection	12139038
38477372	38477395	3	+	28162770	OCIAML2	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	1.4008554342351587	[10]	[160]	9	hSpCas9	negative selection	12139039
38478168	38478191	3	-	28162770	OCIAML2	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	1.261174063808266	[6]	[92]	9	hSpCas9	negative selection	12139040
38478220	38478243	3	-	28162770	OCIAML2	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	0.8717623722049164	[6]	[70]	8	hSpCas9	negative selection	12139041
38478267	38478290	3	-	28162770	OCIAML2	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	-0.18814004148183394	[88]	[432]	-1	hSpCas9	negative selection	12139042
38478377	38478400	3	-	28162770	OCIAML2	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-2.137206091516969	[49]	[62]	-8	hSpCas9	negative selection	12139043
38477890	38477913	3	-	28162770	OCIAML3	viability	ACAGCAGCAGAAGTACACCTGGG	ACVR2B	ENSG00000114739	0.05571106873923504	[166]	[523]	0	hSpCas9	negative selection	12308400
38478390	38478413	3	-	28162770	OCIAML3	viability	AGGCCCACCAGAGGGGATGGTGG	ACVR2B	ENSG00000114739	-0.036012187203276314	[53]	[158]	0	hSpCas9	negative selection	12308401
38479120	38479143	3	+	28162770	OCIAML3	viability	GGCCTCAGGACAAGCAGTCGTGG	ACVR2B	ENSG00000114739	-0.6114246934015728	[124]	[246]	-5	hSpCas9	negative selection	12308402
38454343	38454366	3	-	28162770	OCIAML3	viability	GCGATCCCCAGAGGAGGGCGAGG	ACVR2B	ENSG00000114739	-0.18961738524482774	[16]	[44]	-1	hSpCas9	negative selection	12308403
38477293	38477316	3	+	28162770	OCIAML3	viability	GGCGTGGGGAGGCTGAGACACGG	ACVR2B	ENSG00000114739	-5.681470481574503	[16]	[0]	-9	hSpCas9	negative selection	12308404
38477372	38477395	3	+	28162770	OCIAML3	viability	GGAGCGCTGCGAAGGCGAGCAGG	ACVR2B	ENSG00000114739	1.0249021923203305	[13]	[85]	8	hSpCas9	negative selection	12308405
38478168	38478191	3	-	28162770	OCIAML3	viability	GGCCAGCACCGTGAGCAGGGTGG	ACVR2B	ENSG00000114739	-0.8004585177915895	[29]	[51]	-5	hSpCas9	negative selection	12308406
38478220	38478243	3	-	28162770	OCIAML3	viability	AAAAGGCCAGCAGGACGATGAGG	ACVR2B	ENSG00000114739	-2.9159357352115256	[24]	[9]	-9	hSpCas9	negative selection	12308407
38478267	38478290	3	-	28162770	OCIAML3	viability	ATGGATGTCCACATGACCGTAGG	ACVR2B	ENSG00000114739	0.07320327215670752	[124]	[396]	0	hSpCas9	negative selection	12308408
38478377	38478400	3	-	28162770	OCIAML3	viability	GGGATGGTGGTGGAGGCCCAGGG	ACVR2B	ENSG00000114739	-1.837278791336527	[57]	[48]	-8	hSpCas9	negative selection	12308409