Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 91703
• Symbol: ACY3
• Description: aminoacylase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/ACY3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
67646839	67646862	11	+	26472758	Jiyoye	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.1374550251800647	[193]	[132]	-1	hSpCas9	negative selection	2361
67644808	67644831	11	+	26472758	Jiyoye	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.26376034232513557	[120]	[75]	-2	hSpCas9	negative selection	2362
67645749	67645772	11	+	26472758	Jiyoye	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.8600810663751605	[140]	[192]	6	hSpCas9	negative selection	2363
67645110	67645133	11	+	26472758	Jiyoye	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	-0.3847164231639264	[347]	[200]	-3	hSpCas9	negative selection	2364
67646994	67647017	11	+	26472758	Jiyoye	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.1715471330127314	[72]	[61]	1	hSpCas9	negative selection	2365
67645821	67645844	11	-	26472758	Jiyoye	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.30820893070485234	[180]	[168]	2	hSpCas9	negative selection	2366
67645336	67645359	11	-	26472758	Jiyoye	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	-0.0749099385749803	[344]	[246]	0	hSpCas9	negative selection	2367
67644825	67644848	11	-	26472758	Jiyoye	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.3962870653631371	[132]	[131]	3	hSpCas9	negative selection	2368
67646882	67646905	11	+	26472758	Jiyoye	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.8057247579961482	[21]	[28]	5	hSpCas9	negative selection	2369
67646852	67646875	11	+	26472758	Jiyoye	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	2370
67646839	67646862	11	+	26472758	KBM7	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.4580949768447592	[429,334]	[289,204]	5	hSpCas9	negative selection	193479
67644808	67644831	11	+	26472758	KBM7	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.1543931933514886	[184,212]	[97,111]	1	hSpCas9	negative selection	193480
67645749	67645772	11	+	26472758	KBM7	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.8682108046358806	[410,315]	[472,162]	8	hSpCas9	negative selection	193481
67645110	67645133	11	+	26472758	KBM7	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.15354707593868722	[1389,877]	[633,535]	1	hSpCas9	negative selection	193482
67646994	67647017	11	+	26472758	KBM7	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	1.556838417745467	[371,726]	[1563,95]	9	hSpCas9	negative selection	193483
67645821	67645844	11	-	26472758	KBM7	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.13228807658150732	[801,727]	[296,355]	-1	hSpCas9	negative selection	193484
67645336	67645359	11	-	26472758	KBM7	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.42154765257758764	[1232,959]	[673,694]	4	hSpCas9	negative selection	193485
67644825	67644848	11	-	26472758	KBM7	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.24189533059689886	[482,371]	[195,143]	-2	hSpCas9	negative selection	193486
67646882	67646905	11	+	26472758	KBM7	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	1.1855617719009715	[313,290]	[430,227]	9	hSpCas9	negative selection	193487
67646852	67646875	11	+	26472758	KBM7	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-2.516931469770074	[22,23]	[2,0]	-9	hSpCas9	negative selection	193488
67646839	67646862	11	+	26472758	Raji	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.25893867887221644	[164]	[31]	-2	hSpCas9	negative selection	384597
67644808	67644831	11	+	26472758	Raji	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-1.7102397221378316	[140]	[9]	-8	hSpCas9	negative selection	384598
67645749	67645772	11	+	26472758	Raji	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.6789788123569266	[252]	[93]	6	hSpCas9	negative selection	384599
67645110	67645133	11	+	26472758	Raji	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.8734263624042291	[500]	[212]	7	hSpCas9	negative selection	384600
67646994	67647017	11	+	26472758	Raji	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.6133946946999337	[168]	[59]	6	hSpCas9	negative selection	384601
67645821	67645844	11	-	26472758	Raji	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.047178901167684084	[366]	[87]	0	hSpCas9	negative selection	384602
67645336	67645359	11	-	26472758	Raji	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.021376246667331955	[742]	[174]	0	hSpCas9	negative selection	384603
67644825	67644848	11	-	26472758	Raji	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.21890975207516483	[330]	[65]	-2	hSpCas9	negative selection	384604
67646882	67646905	11	+	26472758	Raji	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.8495857779059526	[109]	[45]	7	hSpCas9	negative selection	384605
67646852	67646875	11	+	26472758	Raji	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	384606
67646839	67646862	11	+	26472758	K562	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.07847405802308471	[373]	[298]	0	hSpCas9	negative selection	575715
67644808	67644831	11	+	26472758	K562	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	1.0571401594738665	[114]	[201]	8	hSpCas9	negative selection	575716
67645749	67645772	11	+	26472758	K562	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.34554065210931273	[302]	[324]	2	hSpCas9	negative selection	575717
67645110	67645133	11	+	26472758	K562	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	-0.0908563070628362	[732]	[580]	0	hSpCas9	negative selection	575718
67646994	67647017	11	+	26472758	K562	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.47678143775782306	[205]	[241]	4	hSpCas9	negative selection	575719
67645821	67645844	11	-	26472758	K562	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.7382439559005418	[578]	[292]	-4	hSpCas9	negative selection	575720
67645336	67645359	11	-	26472758	K562	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	-0.37187697985950097	[1023]	[667]	-2	hSpCas9	negative selection	575721
67644825	67644848	11	-	26472758	K562	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.3943664725608558	[354]	[227]	-3	hSpCas9	negative selection	575722
67646882	67646905	11	+	26472758	K562	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.1919513077723115	[195]	[188]	1	hSpCas9	negative selection	575723
67646852	67646875	11	+	26472758	K562	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-4.755581272333552	[31]	[0]	-9	hSpCas9	negative selection	575724
67642824	67642847	11	+	26627737	DLD1	viability	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.4401746315095489	[374]	[86,78,91]	-4	hSpCas9	negative selection	780620
67644843	67644866	11	-	26627737	DLD1	viability	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.785995316741311	[91]	[40,45,59]	7	hSpCas9	negative selection	780621
67645084	67645107	11	-	26627737	DLD1	viability	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	1.14333928930015	[155]	[147,63,108]	9	hSpCas9	negative selection	780622
67645731	67645754	11	+	26627737	DLD1	viability	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.5086937930579474	[151]	[52,50,93]	5	hSpCas9	negative selection	780623
67646839	67646862	11	+	26627737	DLD1	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.9017980325612617	[587]	[75,114,103]	-7	hSpCas9	negative selection	780624
67646993	67647016	11	+	26627737	DLD1	viability	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	-0.2679142147930512	[711]	[166,276,123]	-3	hSpCas9	negative selection	780625
67642824	67642847	11	+	26627737	GBM cells	viability after 5 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.8158165008058001	[278]	[78,90]	-8	hSpCas9	negative selection	862935
67644843	67644866	11	-	26627737	GBM cells	viability after 5 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.27172313877523213	[77]	[46,53]	4	hSpCas9	negative selection	862936
67645084	67645107	11	-	26627737	GBM cells	viability after 5 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.33267057151111856	[133]	[88,91]	5	hSpCas9	negative selection	862937
67645731	67645754	11	+	26627737	GBM cells	viability after 5 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.035663050116265915	[193]	[80,121]	0	hSpCas9	negative selection	862938
67646839	67646862	11	+	26627737	GBM cells	viability after 5 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.2436905205571147	[169]	[97,55]	-4	hSpCas9	negative selection	862939
67646993	67647016	11	+	26627737	GBM cells	viability after 5 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.26745291206463784	[267]	[172,172]	4	hSpCas9	negative selection	862940
67642824	67642847	11	+	26627737	GBM cells	viability after 13 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.9645256510191695	[278]	[124,38]	-8	hSpCas9	negative selection	945250
67644843	67644866	11	-	26627737	GBM cells	viability after 13 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.5152134199662417	[77]	[65,55]	6	hSpCas9	negative selection	945251
67645084	67645107	11	-	26627737	GBM cells	viability after 13 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.27833575981819536	[133]	[96,80]	3	hSpCas9	negative selection	945252
67645731	67645754	11	+	26627737	GBM cells	viability after 13 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.3437600200846234	[193]	[121,142]	4	hSpCas9	negative selection	945253
67646839	67646862	11	+	26627737	GBM cells	viability after 13 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.16250941337877534	[169]	[77,85]	-2	hSpCas9	negative selection	945254
67646993	67647016	11	+	26627737	GBM cells	viability after 13 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.480304343309672	[267]	[182,218]	6	hSpCas9	negative selection	945255
67642824	67642847	11	+	26627737	GBM cells	viability after 21 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.102745911400246	[278]	[160,122]	-1	hSpCas9	negative selection	1027565
67644843	67644866	11	-	26627737	GBM cells	viability after 21 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.8963780829075544	[77]	[69,86]	8	hSpCas9	negative selection	1027566
67645084	67645107	11	-	26627737	GBM cells	viability after 21 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.7792870534933906	[133]	[137,112]	7	hSpCas9	negative selection	1027567
67645731	67645754	11	+	26627737	GBM cells	viability after 21 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.3318617434605186	[193]	[128,135]	3	hSpCas9	negative selection	1027568
67646839	67646862	11	+	26627737	GBM cells	viability after 21 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.0049074253961572	[169]	[188,181]	8	hSpCas9	negative selection	1027569
67646993	67647016	11	+	26627737	GBM cells	viability after 21 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.280481196521949	[267]	[203,151]	3	hSpCas9	negative selection	1027570
67642824	67642847	11	+	26627737	RPE1	viability after 9 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	1.0388735115535939	[402]	[308,194]	6	hSpCas9	negative selection	1109880
67644843	67644866	11	-	26627737	RPE1	viability after 9 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.9043256746965229	[241]	[136,147]	6	hSpCas9	negative selection	1109881
67645084	67645107	11	-	26627737	RPE1	viability after 9 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.9807015986019416	[214]	[48,240]	6	hSpCas9	negative selection	1109882
67645731	67645754	11	+	26627737	RPE1	viability after 9 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.27678842060365294	[681]	[139,222]	-2	hSpCas9	negative selection	1109883
67646839	67646862	11	+	26627737	RPE1	viability after 9 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.068523269027783	[185]	[184,40]	6	hSpCas9	negative selection	1109884
67646993	67647016	11	+	26627737	RPE1	viability after 9 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.7289800222495345	[689]	[285,450]	5	hSpCas9	negative selection	1109885
67642824	67642847	11	+	26627737	RPE1	viability after 12 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	1.1739010708608266	[402]	[304,179]	7	hSpCas9	negative selection	1192195
67644843	67644866	11	-	26627737	RPE1	viability after 12 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.031600538926795485	[241]	[64,67]	0	hSpCas9	negative selection	1192196
67645084	67645107	11	-	26627737	RPE1	viability after 12 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.3160285376761125	[214]	[8,85]	-2	hSpCas9	negative selection	1192197
67645731	67645754	11	+	26627737	RPE1	viability after 12 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.18707883028136876	[681]	[177,240]	1	hSpCas9	negative selection	1192198
67646839	67646862	11	+	26627737	RPE1	viability after 12 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.1672487979348327	[185]	[204,13]	7	hSpCas9	negative selection	1192199
67646993	67647016	11	+	26627737	RPE1	viability after 12 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.938842744893211	[689]	[231,485]	6	hSpCas9	negative selection	1192200
67642824	67642847	11	+	26627737	RPE1	viability after 15 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	1.4494570413714403	[402]	[460,166]	7	hSpCas9	negative selection	1274510
67644843	67644866	11	-	26627737	RPE1	viability after 15 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.022390170369163354	[241]	[67,70]	0	hSpCas9	negative selection	1274511
67645084	67645107	11	-	26627737	RPE1	viability after 15 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.11388914087867175	[214]	[19,109]	0	hSpCas9	negative selection	1274512
67645731	67645754	11	+	26627737	RPE1	viability after 15 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.18125983603428883	[681]	[161,177]	-1	hSpCas9	negative selection	1274513
67646839	67646862	11	+	26627737	RPE1	viability after 15 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.2448710723145313	[185]	[98,26]	1	hSpCas9	negative selection	1274514
67646993	67647016	11	+	26627737	RPE1	viability after 15 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.7982948641427066	[689]	[342,335]	5	hSpCas9	negative selection	1274515
67642824	67642847	11	+	26627737	RPE1	viability after 18 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	0.9254109290147784	[402]	[280,126]	5	hSpCas9	negative selection	1356825
67644843	67644866	11	-	26627737	RPE1	viability after 18 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.45351263660677077	[241]	[101,75]	3	hSpCas9	negative selection	1356826
67645084	67645107	11	-	26627737	RPE1	viability after 18 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.3118751544768459	[214]	[28,117]	2	hSpCas9	negative selection	1356827
67645731	67645754	11	+	26627737	RPE1	viability after 18 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.4190069780486031	[681]	[185,85]	-3	hSpCas9	negative selection	1356828
67646839	67646862	11	+	26627737	RPE1	viability after 18 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.45267797323428516	[185]	[88,46]	3	hSpCas9	negative selection	1356829
67646993	67647016	11	+	26627737	RPE1	viability after 18 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.9933479911618979	[689]	[230,519]	6	hSpCas9	negative selection	1356830
67642824	67642847	11	+	26627737	HeLa	viability after 8 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-1.1021784375594557	[450]	[50,102,109]	-8	hSpCas9	negative selection	1439140
67644843	67644866	11	-	26627737	HeLa	viability after 8 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.2485120957664093	[160]	[144,30,86]	2	hSpCas9	negative selection	1439141
67645084	67645107	11	-	26627737	HeLa	viability after 8 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.32283327005806495	[182]	[32,83,66]	-3	hSpCas9	negative selection	1439142
67645731	67645754	11	+	26627737	HeLa	viability after 8 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.4457841378327824	[401]	[77,90,199]	-4	hSpCas9	negative selection	1439143
67646839	67646862	11	+	26627737	HeLa	viability after 8 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.8132987111731447	[101]	[32,111,78]	6	hSpCas9	negative selection	1439144
67646993	67647016	11	+	26627737	HeLa	viability after 8 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.880663156520191	[215]	[312,19,213]	7	hSpCas9	negative selection	1439145
67642824	67642847	11	+	26627737	HeLa	viability after 12 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-2.142495698352938	[450]	[56,23,47]	-9	hSpCas9	negative selection	1521455
67644843	67644866	11	-	26627737	HeLa	viability after 12 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	-0.11154933911976839	[160]	[45,54,83]	-1	hSpCas9	negative selection	1521456
67645084	67645107	11	-	26627737	HeLa	viability after 12 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.7708083503316718	[182]	[41,33,57]	-6	hSpCas9	negative selection	1521457
67645731	67645754	11	+	26627737	HeLa	viability after 12 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.992697386171745	[401]	[16,163,58]	-7	hSpCas9	negative selection	1521458
67646839	67646862	11	+	26627737	HeLa	viability after 12 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.1167566596500342	[101]	[88,92,91]	7	hSpCas9	negative selection	1521459
67646993	67647016	11	+	26627737	HeLa	viability after 12 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	1.0995580920505603	[215]	[121,236,207]	7	hSpCas9	negative selection	1521460
67642824	67642847	11	+	26627737	HeLa	viability after 15 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-1.360351664935753	[450]	[66,46,102]	-8	hSpCas9	negative selection	1603770
67644843	67644866	11	-	26627737	HeLa	viability after 15 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.05045947457060729	[160]	[33,102,66]	0	hSpCas9	negative selection	1603771
67645084	67645107	11	-	26627737	HeLa	viability after 15 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.3724020486618951	[182]	[61,23,88]	-3	hSpCas9	negative selection	1603772
67645731	67645754	11	+	26627737	HeLa	viability after 15 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.6885715312526367	[401]	[90,48,169]	-6	hSpCas9	negative selection	1603773
67646839	67646862	11	+	26627737	HeLa	viability after 15 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.2335463521628136	[101]	[38,116,140]	8	hSpCas9	negative selection	1603774
67646993	67647016	11	+	26627737	HeLa	viability after 15 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	1.5949650787569953	[215]	[164,188,458]	9	hSpCas9	negative selection	1603775
67642824	67642847	11	+	26627737	HeLa	viability after 18 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-1.396995491089338	[450]	[42,36,102]	-8	hSpCas9	negative selection	1686085
67644843	67644866	11	-	26627737	HeLa	viability after 18 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.11204162462585154	[160]	[27,85,66]	1	hSpCas9	negative selection	1686086
67645084	67645107	11	-	26627737	HeLa	viability after 18 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.3031834629076824	[182]	[46,19,88]	-3	hSpCas9	negative selection	1686087
67645731	67645754	11	+	26627737	HeLa	viability after 18 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.6923502711284246	[401]	[60,39,169]	-6	hSpCas9	negative selection	1686088
67646839	67646862	11	+	26627737	HeLa	viability after 18 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.245114597845252	[101]	[29,93,140]	8	hSpCas9	negative selection	1686089
67646993	67647016	11	+	26627737	HeLa	viability after 18 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	1.5710146635966518	[215]	[108,147,458]	8	hSpCas9	negative selection	1686090
67642824	67642847	11	+	26627737	HCT116	viability after 6 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-2.83005821044287	[1010]	[51,5]	-9	hSpCas9	negative selection	1768400
67644843	67644866	11	-	26627737	HCT116	viability after 6 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.8089862882154875	[165]	[124,1]	4	hSpCas9	negative selection	1768401
67645084	67645107	11	-	26627737	HCT116	viability after 6 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	1.5962835408405731	[259]	[62,156]	7	hSpCas9	negative selection	1768402
67645731	67645754	11	+	26627737	HCT116	viability after 6 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	1.857699852923774	[126]	[43,87]	8	hSpCas9	negative selection	1768403
67646839	67646862	11	+	26627737	HCT116	viability after 6 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.06275020028231515	[374]	[87,46]	0	hSpCas9	negative selection	1768404
67646993	67647016	11	+	26627737	HCT116	viability after 6 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	1.4189338976420622	[454]	[227,170]	7	hSpCas9	negative selection	1768405
67642824	67642847	11	+	26627737	HCT116	viability after 8 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.18916958525406666	[273]	[159,123,113]	-2	hSpCas9	negative selection	1850715
67644843	67644866	11	-	26627737	HCT116	viability after 8 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.6552326665714892	[64]	[38,80,48]	6	hSpCas9	negative selection	1850716
67645084	67645107	11	-	26627737	HCT116	viability after 8 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.42435311595352987	[76]	[67,44,57]	4	hSpCas9	negative selection	1850717
67645731	67645754	11	+	26627737	HCT116	viability after 8 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.6459304265705453	[259]	[66,95,110]	-7	hSpCas9	negative selection	1850718
67646839	67646862	11	+	26627737	HCT116	viability after 8 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.0007151946666666964	[154]	[84,77,92]	0	hSpCas9	negative selection	1850719
67646993	67647016	11	+	26627737	HCT116	viability after 8 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.275099549080051	[389]	[163,236,375]	3	hSpCas9	negative selection	1850720
67642824	67642847	11	+	26627737	HCT116	viability after 9 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-1.4168225856276697	[1010]	[18,165]	-7	hSpCas9	negative selection	1933030
67644843	67644866	11	-	26627737	HCT116	viability after 9 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	-0.35494737204694715	[165]	[56,16]	-3	hSpCas9	negative selection	1933031
67645084	67645107	11	-	26627737	HCT116	viability after 9 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.3740901201174476	[259]	[71,38]	-3	hSpCas9	negative selection	1933032
67645731	67645754	11	+	26627737	HCT116	viability after 9 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	1.3605925376589214	[126]	[71,98]	8	hSpCas9	negative selection	1933033
67646839	67646862	11	+	26627737	HCT116	viability after 9 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-3.593115494288545	[374]	[14,2]	-9	hSpCas9	negative selection	1933034
67646993	67647016	11	+	26627737	HCT116	viability after 9 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	1.0103657440956202	[454]	[251,238]	7	hSpCas9	negative selection	1933035
67642824	67642847	11	+	26627737	HCT116	viability after 12 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.4748564659885477	[273]	[98,93,117]	-5	hSpCas9	negative selection	2015345
67644843	67644866	11	-	26627737	HCT116	viability after 12 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	1.2804993202003998	[64]	[54,148,48]	8	hSpCas9	negative selection	2015346
67645084	67645107	11	-	26627737	HCT116	viability after 12 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.5181557917447059	[76]	[50,79,43]	5	hSpCas9	negative selection	2015347
67645731	67645754	11	+	26627737	HCT116	viability after 12 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.5787561227896615	[259]	[71,125,78]	-6	hSpCas9	negative selection	2015348
67646839	67646862	11	+	26627737	HCT116	viability after 12 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.4147590663892591	[154]	[87,84,153]	4	hSpCas9	negative selection	2015349
67646993	67647016	11	+	26627737	HCT116	viability after 12 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.08239445641186804	[389]	[195,181,273]	0	hSpCas9	negative selection	2015350
67642824	67642847	11	+	26627737	HCT116	viability after 15 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.6852526217069865	[273]	[132,78,85]	-6	hSpCas9	negative selection	2097660
67644843	67644866	11	-	26627737	HCT116	viability after 15 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	1.2020525419922954	[64]	[39,120,90]	8	hSpCas9	negative selection	2097661
67645084	67645107	11	-	26627737	HCT116	viability after 15 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	0.0510670828692954	[76]	[41,50,43]	0	hSpCas9	negative selection	2097662
67645731	67645754	11	+	26627737	HCT116	viability after 15 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.15805759019473373	[259]	[126,169,103]	-2	hSpCas9	negative selection	2097663
67646839	67646862	11	+	26627737	HCT116	viability after 15 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.9207564355251556	[154]	[137,208,154]	7	hSpCas9	negative selection	2097664
67646993	67647016	11	+	26627737	HCT116	viability after 15 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.1407923195369915	[389]	[318,218,211]	1	hSpCas9	negative selection	2097665
67642824	67642847	11	+	26627737	HCT116	viability after 18 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.5663785230420267	[273]	[89,40,142]	-5	hSpCas9	negative selection	2179975
67644843	67644866	11	-	26627737	HCT116	viability after 18 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.3286650593001228	[64]	[14,69,30]	3	hSpCas9	negative selection	2179976
67645084	67645107	11	-	26627737	HCT116	viability after 18 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.17714576699191498	[76]	[43,34,18]	-2	hSpCas9	negative selection	2179977
67645731	67645754	11	+	26627737	HCT116	viability after 18 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.4135724116732513	[259]	[79,143,53]	-4	hSpCas9	negative selection	2179978
67646839	67646862	11	+	26627737	HCT116	viability after 18 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.053295690738884	[154]	[144,112,213]	7	hSpCas9	negative selection	2179979
67646993	67647016	11	+	26627737	HCT116	viability after 18 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.30726560428315014	[389]	[183,226,291]	2	hSpCas9	negative selection	2179980
67645766	67645789	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	0.01580643820223375	[3,3]	[3,2]	0	hSpCas9	positive selection	2968811
67645750	67645773	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.24802002835958734	[3,3]	[2,4]	5	hSpCas9	positive selection	2968812
67646840	67646863	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.5474975549494285	[3,4]	[4,6]	9	hSpCas9	positive selection	2968813
67646883	67646906	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.08474742578652833	[2,2]	[3,1]	1	hSpCas9	positive selection	2968814
67645766	67645789	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	0.3735346792942489	[3,3]	[4,2]	6	hSpCas9	positive selection	3036669
67645750	67645773	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.24920945047666448	[3,3]	[3,2]	4	hSpCas9	positive selection	3036670
67646840	67646863	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.7210727268511357	[3,3]	[5,4]	9	hSpCas9	positive selection	3036671
67646883	67646906	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.08820199404912232	[2,2]	[2,1]	1	hSpCas9	positive selection	3036672
67644816	67644839		-	24336571	A375	resistance to PLX after 7 days	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.1369944962998213	[6,5]	[4,6]	-4	hSpCas9	positive selection	3160692
67642802	67642825		+	24336571	A375	resistance to PLX after 7 days	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.3096532152789133	[4,4]	[3,3]	-8	hSpCas9	positive selection	3160703
67644808	67644831		+	24336571	A375	resistance to PLX after 7 days	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.0460974902946778	[6,7]	[6,7]	1	hSpCas9	positive selection	3160714
67642828	67642851		-	24336571	A375	resistance to PLX after 7 days	GTACCCCGTGTTCATTAACGAGG	ACY3	ENSG00000132744	-0.1343122135823882	[6,5]	[5,4]	-4	hSpCas9	positive selection	3160723
67644816	67644839		-	24336571	A375	resistance to PLX after 14 days	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.24931604248007788	[8,6]	[2,2]	-3	hSpCas9	positive selection	3218485
67642802	67642825		+	24336571	A375	resistance to PLX after 14 days	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.16545704573505082	[5,3]	[1,1]	-2	hSpCas9	positive selection	3218496
67644808	67644831		+	24336571	A375	resistance to PLX after 14 days	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.6365961674441507	[4,7]	[4,4]	6	hSpCas9	positive selection	3218507
67642828	67642851		-	24336571	A375	resistance to PLX after 14 days	GTACCCCGTGTTCATTAACGAGG	ACY3	ENSG00000132744	-0.22876614296491626	[6,5]	[1,2]	-2	hSpCas9	positive selection	3218516
67644816	67644839		-	24336571	A375	viability after 7 days	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.013746344822030965	[6]	[6,5]	0	hSpCas9	negative selection	3276278
67642802	67642825		+	24336571	A375	viability after 7 days	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.16415268989500498	[4]	[4,4]	2	hSpCas9	negative selection	3276289
67644808	67644831		+	24336571	A375	viability after 7 days	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.23907010540163715	[8]	[6,7]	-3	hSpCas9	negative selection	3276300
67642828	67642851		-	24336571	A375	viability after 7 days	GTACCCCGTGTTCATTAACGAGG	ACY3	ENSG00000132744	-0.6601206891216005	[10]	[6,5]	-7	hSpCas9	negative selection	3276309
67644816	67644839		-	24336571	A375	viability after 14 days	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.27517761748211067	[6]	[8,6]	3	hSpCas9	negative selection	3334071
67642802	67642825		+	24336571	A375	viability after 14 days	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.17031608205569815	[4]	[5,3]	2	hSpCas9	negative selection	3334082
67644808	67644831		+	24336571	A375	viability after 14 days	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.381192033095431	[8]	[4,7]	-4	hSpCas9	negative selection	3334093
67642828	67642851		-	24336571	A375	viability after 14 days	GTACCCCGTGTTCATTAACGAGG	ACY3	ENSG00000132744	-0.5635767673049326	[10]	[6,5]	-6	hSpCas9	negative selection	3334102
67644808	67644831	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	1.2333635391574511	[75,53]	[0,0]	5	hSpCas9	positive selection	3335487
67644816	67644839	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	1.8136242293213294	[46,39]	[0,0]	7	hSpCas9	positive selection	3335488
67642802	67642825	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.2966049478635829	[133,114]	[0,0]	1	hSpCas9	positive selection	3335489
67645330	67645353	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	2.1645690705259826	[272,272]	[7,7]	7	hSpCas9	positive selection	3354733
67645852	67645875	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3354734
67645709	67645732	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.2662357446111776	[183,183]	[0,0]	-2	hSpCas9	positive selection	3354735
67645766	67645789	11	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	-0.0221600848187234	[]	[]	0	hSpCas9	negative selection	3404761
67645749	67645772	11	+	26780180	HT29	viability (Avana library 4 designs)	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.0663180972462469	[]	[]	0	hSpCas9	negative selection	3404762
67646839	67646862	11	+	26780180	HT29	viability (Avana library 4 designs)	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.359466673126215	[]	[]	1	hSpCas9	negative selection	3404763
67646882	67646905	11	+	26780180	HT29	viability (Avana library 4 designs)	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	1.16767996199675	[]	[]	4	hSpCas9	negative selection	3404764
67646839	67646862	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	3.34886859974067	[]	[]	5	hSpCas9	negative selection	3476457
67645766	67645789	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	0.413364577549471	[]	[]	0	hSpCas9	negative selection	3476458
67646882	67646905	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-3.55426206272118	[]	[]	-4	hSpCas9	negative selection	3476459
67645749	67645772	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	2.77078417533981	[]	[]	4	hSpCas9	negative selection	3476460
67645844	67645867	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCTCTTGTCACCTCATATGGG	ACY3	ENSG00000132744	1.45676516859755	[]	[]	2	hSpCas9	negative selection	3476461
67645871	67645894	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACAGTTCCAGGCCCACCCCGG	ACY3	ENSG00000132744	3.07057586502618	[]	[]	5	hSpCas9	negative selection	3476462
67646839	67646862	11	+	26780180	A375	viability (Avana lentiGuide)	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	3.04164214076575	[]	[]	3	hSpCas9	negative selection	3585116
67645766	67645789	11	-	26780180	A375	viability (Avana lentiGuide)	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	-6.54267616066257	[]	[]	-9	hSpCas9	negative selection	3585117
67646882	67646905	11	+	26780180	A375	viability (Avana lentiGuide)	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-3.69669132754174	[]	[]	-6	hSpCas9	negative selection	3585118
67645749	67645772	11	+	26780180	A375	viability (Avana lentiGuide)	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	1.66866252414496	[]	[]	2	hSpCas9	negative selection	3585119
67645844	67645867	11	+	26780180	A375	viability (Avana lentiGuide)	GGGCTCTTGTCACCTCATATGGG	ACY3	ENSG00000132744	0.38038452544651	[]	[]	0	hSpCas9	negative selection	3585120
67645871	67645894	11	-	26780180	A375	viability (Avana lentiGuide)	CCACAGTTCCAGGCCCACCCCGG	ACY3	ENSG00000132744	3.28475525423296	[]	[]	3	hSpCas9	negative selection	3585121
67646839	67646862	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.03913590991814996	[5]	[5,4]	0	hSpCas9	positive selection	3693775
67645766	67645789	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	-0.41354710524251087	[4]	[4,1]	-6	hSpCas9	positive selection	3693776
67646882	67646905	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.19294068690132368	[4]	[5,3]	5	hSpCas9	positive selection	3693777
67645749	67645772	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.15494489814709095	[5]	[5,5]	4	hSpCas9	positive selection	3693778
67645844	67645867	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCTCTTGTCACCTCATATGGG	ACY3	ENSG00000132744	0.1899866455375253	[4]	[5,5]	5	hSpCas9	positive selection	3693779
67645871	67645894	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACAGTTCCAGGCCCACCCCGG	ACY3	ENSG00000132744	0.05382877040660137	[5]	[5,4]	1	hSpCas9	positive selection	3693780
67646839	67646862	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.03435829098803997	[6]	[4,5]	0	hSpCas9	positive selection	3802382
67645766	67645789	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGACCTGCACAACACCACGG	ACY3	ENSG00000132744	-0.1492400291663128	[5]	[3,4]	-2	hSpCas9	positive selection	3802383
67646882	67646905	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.18648503449049023	[4]	[3,4]	4	hSpCas9	positive selection	3802384
67645749	67645772	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.2096908964499727	[5]	[4,6]	5	hSpCas9	positive selection	3802385
67645844	67645867	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCTCTTGTCACCTCATATGGG	ACY3	ENSG00000132744	0.26614106828807105	[5]	[5,6]	7	hSpCas9	positive selection	3802386
67645871	67645894	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACAGTTCCAGGCCCACCCCGG	ACY3	ENSG00000132744	0.1000004682188177	[7]	[6,7]	2	hSpCas9	positive selection	3802387
67644816	67644839	11	-	26780180	A375	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	1.07937094379483	[]	[]	5	hSpCas9	negative selection	3910982
67642802	67642825	11	+	26780180	A375	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.198425164135884	[]	[]	-6	hSpCas9	negative selection	3910983
67644808	67644831	11	+	26780180	A375	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.622717255228841	[]	[]	2	hSpCas9	negative selection	3910984
67645709	67645732	11	+	26780180	A375	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	1.62775070087901	[]	[]	8	hSpCas9	negative selection	3910985
67645852	67645875	11	+	26780180	A375	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	1.23486823405449	[]	[]	6	hSpCas9	negative selection	3910986
67645330	67645353	11	-	26780180	A375	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	1.42519580245948	[]	[]	7	hSpCas9	negative selection	3910987
67644816	67644839	11	-	26780180	HT29	viability (GeCKOv2 library)	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	1.12646941793736	[]	[]	5	hSpCas9	negative selection	4018948
67642802	67642825	11	+	26780180	HT29	viability (GeCKOv2 library)	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.202349295933004	[]	[]	0	hSpCas9	negative selection	4018949
67644808	67644831	11	+	26780180	HT29	viability (GeCKOv2 library)	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.574787590046035	[]	[]	2	hSpCas9	negative selection	4018950
67645709	67645732	11	+	26780180	HT29	viability (GeCKOv2 library)	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	1.66114595919089	[]	[]	8	hSpCas9	negative selection	4018951
67645852	67645875	11	+	26780180	HT29	viability (GeCKOv2 library)	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	1.69878704977522	[]	[]	8	hSpCas9	negative selection	4018952
67645330	67645353	11	-	26780180	HT29	viability (GeCKOv2 library)	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	1.02228641890726	[]	[]	4	hSpCas9	negative selection	4018953
67644816	67644839	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.13132078880355108	[2]	[1,1]	-3	hSpCas9	positive selection	4188784
67642802	67642825	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.7813300433645114	[1]	[0,0]	-9	hSpCas9	positive selection	4188795
67644808	67644831	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.13018216960216245	[3]	[2,2]	3	hSpCas9	positive selection	4188807
67642828	67642851	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACCCCGTGTTCATTAACGAGG	ACY3	ENSG00000132744	-0.055394827551948134	[2]	[2,0]	-1	hSpCas9	positive selection	4188816
67644816	67644839	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	1.6628230021435464	[2]	[5,4,3,4]	9	hSpCas9	positive selection	4252806
67642802	67642825	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.5351303303814681	[3]	[0,0,0,3]	3	hSpCas9	positive selection	4252817
67644808	67644831	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.08816972660814973	[3]	[3,1,0,0]	0	hSpCas9	positive selection	4252829
67642828	67642851	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACCCCGTGTTCATTAACGAGG	ACY3	ENSG00000132744	0.9005419035878034	[1]	[1,1,1,0]	6	hSpCas9	positive selection	4252838
67644808	67644831	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.2857460867881474	[2]	[2,1]	6	hSpCas9	positive selection	4254410
67644816	67644839	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.06483317777528438	[2]	[2,1]	1	hSpCas9	positive selection	4254411
67642802	67642825	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.3553196960942869	[2]	[3,2]	7	hSpCas9	positive selection	4254412
67645330	67645353	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.014117038861411621	[3]	[3,1]	0	hSpCas9	positive selection	4318693
67645852	67645875	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.5238643341312721	[3]	[1,0]	-8	hSpCas9	positive selection	4318694
67645709	67645732	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	0.1649451198168369	[3]	[3,2]	3	hSpCas9	positive selection	4318695
67644833	67644855	11	+	27760321	OCIAML3	viability	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	0.41094889420213976	[174,127]	[129,189]	5	hSpCas9	negative selection	4376015
67645283	67645305	11	-	27760321	OCIAML3	viability	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.5725647434842676	[436,336]	[415,486]	6	hSpCas9	negative selection	4376016
67645732	67645754	11	+	27760321	OCIAML3	viability	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.29073771696203254	[319,339]	[241,415]	3	hSpCas9	negative selection	4376017
67645859	67645881	11	+	27760321	OCIAML3	viability	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.06078571161572821	[1021,879]	[717,845]	0	hSpCas9	negative selection	4376018
67646837	67646859	11	+	27760321	OCIAML3	viability	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.1771601149520354	[506,476]	[271,429]	-2	hSpCas9	negative selection	4376019
67644833	67644855	11	+	27760321	OCIAML2	viability	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	-0.028804843476472497	[174,127]	[118,118]	0	hSpCas9	negative selection	4459478
67645283	67645305	11	-	27760321	OCIAML2	viability	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.8595736746844915	[436,336]	[452,709]	9	hSpCas9	negative selection	4459479
67645732	67645754	11	+	27760321	OCIAML2	viability	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.36176915656992803	[319,339]	[341,348]	5	hSpCas9	negative selection	4459480
67645859	67645881	11	+	27760321	OCIAML2	viability	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.08816331638966779	[1021,879]	[745,906]	1	hSpCas9	negative selection	4459481
67646837	67646859	11	+	27760321	OCIAML2	viability	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	0.33982575457806397	[506,476]	[403,635]	4	hSpCas9	negative selection	4459482
67644833	67644855	11	+	27760321	MV411	viability	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	2.2233117071697728	[174,127]	[505,396]	9	hSpCas9	negative selection	4542941
67645283	67645305	11	-	27760321	MV411	viability	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.4269673974258648	[436,336]	[367,299]	3	hSpCas9	negative selection	4542942
67645732	67645754	11	+	27760321	MV411	viability	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.3518146230184713	[319,339]	[203,122]	-2	hSpCas9	negative selection	4542943
67645859	67645881	11	+	27760321	MV411	viability	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.27133266466057115	[1021,879]	[355,1354]	2	hSpCas9	negative selection	4542944
67646837	67646859	11	+	27760321	MV411	viability	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	0.4682491344078681	[506,476]	[341,610]	3	hSpCas9	negative selection	4542945
67644833	67644855	11	+	27760321	HL60	viability	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	1.465048919033027	[174,127]	[302,375]	9	hSpCas9	negative selection	4626404
67645283	67645305	11	-	27760321	HL60	viability	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	-0.08053824389913844	[436,336]	[305,286]	-1	hSpCas9	negative selection	4626405
67645732	67645754	11	+	27760321	HL60	viability	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.4876408405771186	[319,339]	[221,162]	-5	hSpCas9	negative selection	4626406
67645859	67645881	11	+	27760321	HL60	viability	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.1329834954511293	[1021,879]	[863,833]	1	hSpCas9	negative selection	4626407
67646837	67646859	11	+	27760321	HL60	viability	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	0.3179659936532525	[506,476]	[530,469]	4	hSpCas9	negative selection	4626408
67644833	67644855	11	+	27760321	HT1080	viability	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	1.049532901524576	[127,99]	[51,139]	6	hSpCas9	negative selection	4709867
67645283	67645305	11	-	27760321	HT1080	viability	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	2.0483679770206695	[336,262]	[764,197]	9	hSpCas9	negative selection	4709868
67645732	67645754	11	+	27760321	HT1080	viability	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.20362714367945303	[339,265]	[153,50]	-1	hSpCas9	negative selection	4709869
67645859	67645881	11	+	27760321	HT1080	viability	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.781685253611452	[879,686]	[527,545]	4	hSpCas9	negative selection	4709870
67646837	67646859	11	+	27760321	HT1080	viability	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.4943011743106839	[476,371]	[120,118]	-2	hSpCas9	negative selection	4709871
67644833	67644855	11	+	27760321	HT29	viability after 7 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	-0.016057252742004424	[127,99]	[217,174,54]	0	hSpCas9	negative selection	4793330
67645283	67645305	11	-	27760321	HT29	viability after 7 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.46320933396957975	[336,262]	[470,493,617]	7	hSpCas9	negative selection	4793331
67645732	67645754	11	+	27760321	HT29	viability after 7 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.6033357619119505	[339,265]	[247,141,373]	-7	hSpCas9	negative selection	4793332
67645859	67645881	11	+	27760321	HT29	viability after 7 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.12451876797448591	[879,686]	[1032,1067,1179]	2	hSpCas9	negative selection	4793333
67646837	67646859	11	+	27760321	HT29	viability after 7 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.05929790516097122	[476,371]	[642,433,510]	-1	hSpCas9	negative selection	4793334
67644833	67644855	11	+	27760321	HT29	viability after 25 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	0.4500982991946296	[127,99]	[225,123,180]	5	hSpCas9	negative selection	4876793
67645283	67645305	11	-	27760321	HT29	viability after 25 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.6429652920796747	[336,262]	[450,413,769]	7	hSpCas9	negative selection	4876794
67645732	67645754	11	+	27760321	HT29	viability after 25 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.7618954670032095	[339,265]	[103,195,331]	-6	hSpCas9	negative selection	4876795
67645859	67645881	11	+	27760321	HT29	viability after 25 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.011863440621189936	[879,686]	[922,860,923]	0	hSpCas9	negative selection	4876796
67646837	67646859	11	+	27760321	HT29	viability after 25 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.39063657790986117	[476,371]	[391,381,329]	-4	hSpCas9	negative selection	4876797
67644833	67644855	11	+	27760321	HT29	viability after 22 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	0.5681970740990601	[127,99]	[298,133,149]	6	hSpCas9	negative selection	4960256
67645283	67645305	11	-	27760321	HT29	viability after 22 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.42991115382262024	[336,262]	[413,526,461]	4	hSpCas9	negative selection	4960257
67645732	67645754	11	+	27760321	HT29	viability after 22 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.24417219933221815	[339,265]	[313,366,204]	-3	hSpCas9	negative selection	4960258
67645859	67645881	11	+	27760321	HT29	viability after 22 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	-0.07250250211970632	[879,686]	[1139,636,798]	0	hSpCas9	negative selection	4960259
67646837	67646859	11	+	27760321	HT29	viability after 22 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.09745255014414991	[476,371]	[454,470,449]	-1	hSpCas9	negative selection	4960260
67644833	67644855	11	+	27760321	HT29	viability after 19 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	0.4299708951932262	[127,99]	[232,127,171]	4	hSpCas9	negative selection	5043719
67645283	67645305	11	-	27760321	HT29	viability after 19 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.5798253457722395	[336,262]	[673,555,331]	6	hSpCas9	negative selection	5043720
67645732	67645754	11	+	27760321	HT29	viability after 19 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.4987166005583227	[339,265]	[187,196,340]	-4	hSpCas9	negative selection	5043721
67645859	67645881	11	+	27760321	HT29	viability after 19 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	-0.21419970957454249	[879,686]	[895,935,507]	-2	hSpCas9	negative selection	5043722
67646837	67646859	11	+	27760321	HT29	viability after 19 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.05965669944757376	[476,371]	[641,346,427]	0	hSpCas9	negative selection	5043723
67644833	67644855	11	+	27760321	HT29	viability after 16 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	-0.024251144687333248	[127,99]	[206,123,52]	0	hSpCas9	negative selection	5127182
67645283	67645305	11	-	27760321	HT29	viability after 16 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.9155107142463931	[336,262]	[584,427,886]	9	hSpCas9	negative selection	5127183
67645732	67645754	11	+	27760321	HT29	viability after 16 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.3294735900492022	[339,265]	[155,333,306]	-4	hSpCas9	negative selection	5127184
67645859	67645881	11	+	27760321	HT29	viability after 16 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.26016918855014093	[879,686]	[1125,1222,802]	3	hSpCas9	negative selection	5127185
67646837	67646859	11	+	27760321	HT29	viability after 16 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	-0.33985421165386526	[476,371]	[529,308,302]	-4	hSpCas9	negative selection	5127186
67644833	67644855	11	+	27760321	HT29	viability after 13 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	0.5525474090155971	[127,99]	[231,209,142]	7	hSpCas9	negative selection	5210645
67645283	67645305	11	-	27760321	HT29	viability after 13 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.8271221107826943	[336,262]	[708,524,617]	9	hSpCas9	negative selection	5210646
67645732	67645754	11	+	27760321	HT29	viability after 13 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.6587073677387362	[339,265]	[262,165,237]	-6	hSpCas9	negative selection	5210647
67645859	67645881	11	+	27760321	HT29	viability after 13 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	0.09834985024341569	[879,686]	[936,1227,766]	1	hSpCas9	negative selection	5210648
67646837	67646859	11	+	27760321	HT29	viability after 13 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	0.036643628923156174	[476,371]	[550,507,458]	0	hSpCas9	negative selection	5210649
67644833	67644855	11	+	27760321	HT29	viability after 10 days	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	0.5567102642441784	[127,99]	[232,216,178]	7	hSpCas9	negative selection	5294108
67645283	67645305	11	-	27760321	HT29	viability after 10 days	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	0.0930364837202717	[336,262]	[550,281,362]	1	hSpCas9	negative selection	5294109
67645732	67645754	11	+	27760321	HT29	viability after 10 days	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.15088523187927463	[339,265]	[183,263,566]	-2	hSpCas9	negative selection	5294110
67645859	67645881	11	+	27760321	HT29	viability after 10 days	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	-0.07740079552160295	[879,686]	[998,1108,683]	-1	hSpCas9	negative selection	5294111
67646837	67646859	11	+	27760321	HT29	viability after 10 days	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	0.20392076284881247	[476,371]	[677,514,634]	2	hSpCas9	negative selection	5294112
67644833	67644855	11	+	27760321	MOLM13	viability	CTATAGGCTTCCATCTCAAAGG	ACY3	ENSG00000132744	-0.6896067073987266	[174,127]	[65,40]	-4	hSpCas9	negative selection	5377571
67645283	67645305	11	-	27760321	MOLM13	viability	TGGCCAAAAATGGACTGGGTGG	ACY3	ENSG00000132744	-0.07242440169488845	[436,336]	[163,241]	0	hSpCas9	negative selection	5377572
67645732	67645754	11	+	27760321	MOLM13	viability	GAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.7082694478494316	[319,339]	[139,92]	-4	hSpCas9	negative selection	5377573
67645859	67645881	11	+	27760321	MOLM13	viability	CATATGGGTCGTCCGGGGTGGG	ACY3	ENSG00000132744	1.1773658271165104	[1021,879]	[1054,1341]	8	hSpCas9	negative selection	5377574
67646837	67646859	11	+	27760321	MOLM13	viability	GAGGTCATGGTCCACGTAGCGG	ACY3	ENSG00000132744	0.37653600294567935	[506,476]	[472,264]	2	hSpCas9	negative selection	5377575
67647515	67647538	11	-	27661255	K562	viability	GAAGCCCAGATCCGCATCAGCGG	ACY3	ENSG00000132744	0.04579427431695726	[722,824]	[748,540]	1	dCas9-KRAB	negative selection	5460830
67647537	67647560	11	-	27661255	K562	viability	GACGCCAGTCCTGGTGGCCCGGG	ACY3	ENSG00000132744	0.27876582575389874	[184,182]	[193,164]	8	dCas9-KRAB	negative selection	5460831
67647543	67647566	11	-	27661255	K562	viability	GAGTTAGACGCCAGTCCTGGTGG	ACY3	ENSG00000132744	0.22633635176796751	[1153,1325]	[1292,1038]	7	dCas9-KRAB	negative selection	5460832
67650252	67650275	11	-	27661255	K562	viability	GCTGGGAGGCATGATCTAATTGG	ACY3	ENSG00000132744	0.1330928718289593	[577,497]	[498,449]	4	dCas9-KRAB	negative selection	5460833
67650640	67650663	11	-	27661255	K562	viability	GGGCGGAGTGACAGCCCCACGGG	ACY3	ENSG00000132744	0.23993090583007493	[635,573]	[574,568]	7	dCas9-KRAB	negative selection	5460834
67644808	67644831	11	+	27260156	BXPC3	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3600704102222049	[205]	[208,303,323,272]	7	hSpCas9	negative selection	5526870
67644816	67644839	11	-	27260156	BXPC3	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.168437443098301	[262]	[303,331,268,329]	3	hSpCas9	negative selection	5526871
67642802	67642825	11	+	27260156	BXPC3	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.16023273930960857	[434]	[582,413,521,507]	3	hSpCas9	negative selection	5526872
67645330	67645353	11	-	27260156	BXPC3	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.028436504104504712	[623]	[639,531,657,861]	0	hSpCas9	negative selection	5591153
67645852	67645875	11	+	27260156	BXPC3	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.01197476535423049	[464]	[441,422,530,545]	0	hSpCas9	negative selection	5591154
67645709	67645732	11	+	27260156	BXPC3	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.3381957889073395	[541]	[422,539,364,458]	-6	hSpCas9	negative selection	5591155
67644808	67644831	11	+	27260156	A673	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3739932123169061	[205]	[371,232,354,329]	8	hSpCas9	negative selection	5648121
67644816	67644839	11	-	27260156	A673	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.059081729818282636	[262]	[252,290,225,444]	-1	hSpCas9	negative selection	5648122
67642802	67642825	11	+	27260156	A673	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.40921213123635936	[434]	[765,646,687,680]	8	hSpCas9	negative selection	5648123
67645330	67645353	11	-	27260156	A673	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.08566481123375169	[623]	[799,736,882,757]	2	hSpCas9	negative selection	5712404
67645852	67645875	11	+	27260156	A673	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.14286310213601267	[464]	[672,535,398,428]	-4	hSpCas9	negative selection	5712405
67645709	67645732	11	+	27260156	A673	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.08435840149681174	[541]	[659,571,665,558]	-2	hSpCas9	negative selection	5712406
67644808	67644831	11	+	27260156	A375	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3967786758590728	[205]	[267,415,321,277]	6	hSpCas9	negative selection	5769372
67644816	67644839	11	-	27260156	A375	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.12276372965370597	[262]	[396,284,130,311]	-2	hSpCas9	negative selection	5769373
67642802	67642825	11	+	27260156	A375	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.41638341170972965	[434]	[580,788,663,688]	6	hSpCas9	negative selection	5769374
67645330	67645353	11	-	27260156	A375	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.2583448799749454	[623]	[616,1017,396,475]	-4	hSpCas9	negative selection	5833655
67645852	67645875	11	+	27260156	A375	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.15857712213080047	[464]	[763,848,409,452]	2	hSpCas9	negative selection	5833656
67645709	67645732	11	+	27260156	A375	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.14552021957779013	[541]	[697,712,485,427]	-2	hSpCas9	negative selection	5833657
67644808	67644831	11	+	27260156	COLO741	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.24232259910260334	[205]	[351,374,216]	5	hSpCas9	negative selection	5890623
67644816	67644839	11	-	27260156	COLO741	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.28054848569318147	[262]	[300,220,306]	-6	hSpCas9	negative selection	5890624
67642802	67642825	11	+	27260156	COLO741	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.29154728618447656	[434]	[820,661,575]	6	hSpCas9	negative selection	5890625
67645330	67645353	11	-	27260156	COLO741	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.005197734946565669	[623]	[868,756,763]	0	hSpCas9	negative selection	5954906
67645852	67645875	11	+	27260156	COLO741	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.2843104615225366	[464]	[435,628,399]	-6	hSpCas9	negative selection	5954907
67645709	67645732	11	+	27260156	COLO741	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	0.018777063349909584	[541]	[820,700,598]	0	hSpCas9	negative selection	5954908
67644808	67644831	11	+	27260156	CAL120	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3213469162385614	[205]	[282,398,273]	5	hSpCas9	negative selection	6011874
67644816	67644839	11	-	27260156	CAL120	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.6275886403766466	[262]	[170,175,280]	-7	hSpCas9	negative selection	6011875
67642802	67642825	11	+	27260156	CAL120	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.49264517734261	[434]	[932,762,616]	7	hSpCas9	negative selection	6011876
67645330	67645353	11	-	27260156	CAL120	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.2173026797364202	[623]	[961,867,886]	3	hSpCas9	negative selection	6076157
67645852	67645875	11	+	27260156	CAL120	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.5105286518408542	[464]	[482,287,457]	-6	hSpCas9	negative selection	6076158
67645709	67645732	11	+	27260156	CAL120	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.2183510245972524	[541]	[862,474,445]	-3	hSpCas9	negative selection	6076159
67644808	67644831	11	+	27260156	CADOES1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3502084128818792	[205]	[233,189,354,195]	6	hSpCas9	negative selection	6133125
67644816	67644839	11	-	27260156	CADOES1	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.1343324509289744	[262]	[247,296,162,181]	-2	hSpCas9	negative selection	6133126
67642802	67642825	11	+	27260156	CADOES1	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.021378623884538622	[434]	[455,388,368,428]	0	hSpCas9	negative selection	6133127
67645330	67645353	11	-	27260156	CADOES1	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.14998735174184125	[623]	[506,684,820,559]	2	hSpCas9	negative selection	6197408
67645852	67645875	11	+	27260156	CADOES1	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.30876219691065143	[464]	[779,275,640,440]	5	hSpCas9	negative selection	6197409
67645709	67645732	11	+	27260156	CADOES1	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.4598249365140272	[541]	[429,385,332,314]	-7	hSpCas9	negative selection	6197410
67644808	67644831	11	+	27260156	EWS502	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.24050858799875463	[205]	[180,273,273,313]	4	hSpCas9	negative selection	6254376
67644816	67644839	11	-	27260156	EWS502	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.1061163537856914	[262]	[223,275,311,223]	-2	hSpCas9	negative selection	6254377
67642802	67642825	11	+	27260156	EWS502	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.3455984156272181	[434]	[436,546,615,772]	6	hSpCas9	negative selection	6254378
67645330	67645353	11	-	27260156	EWS502	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.19893434000930893	[623]	[766,792,573,902]	3	hSpCas9	negative selection	6318659
67645852	67645875	11	+	27260156	EWS502	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.13677539488276041	[464]	[794,287,584,470]	2	hSpCas9	negative selection	6318660
67645709	67645732	11	+	27260156	EWS502	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.15176958533257423	[541]	[489,579,367,633]	-3	hSpCas9	negative selection	6318661
67644808	67644831	11	+	27260156	EW8	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.583393950789168	[205]	[318,208,227,254]	8	hSpCas9	negative selection	6375627
67644816	67644839	11	-	27260156	EW8	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.01947951668817738	[262]	[201,288,146,235]	0	hSpCas9	negative selection	6375628
67642802	67642825	11	+	27260156	EW8	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.07991347507111043	[434]	[344,566,298,288]	1	hSpCas9	negative selection	6375629
67645330	67645353	11	-	27260156	EW8	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.24187983540788843	[623]	[676,331,317,427]	-4	hSpCas9	negative selection	6439910
67645852	67645875	11	+	27260156	EW8	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.16534761908161266	[464]	[721,410,241,377]	3	hSpCas9	negative selection	6439911
67645709	67645732	11	+	27260156	EW8	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	0.18621114824669244	[541]	[803,362,450,420]	3	hSpCas9	negative selection	6439912
67644808	67644831	11	+	27260156	CORL105	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.11832911687914893	[205]	[339,300,302,111]	2	hSpCas9	negative selection	6496878
67644816	67644839	11	-	27260156	CORL105	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.15774285929182885	[262]	[271,295,488,337]	3	hSpCas9	negative selection	6496879
67642802	67642825	11	+	27260156	CORL105	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.0824037511296065	[434]	[410,485,524,505]	-1	hSpCas9	negative selection	6496880
67645330	67645353	11	-	27260156	CORL105	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.23474055285387235	[623]	[679,535,716,568]	-4	hSpCas9	negative selection	6561161
67645852	67645875	11	+	27260156	CORL105	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.18605039839963222	[464]	[415,529,511,457]	-3	hSpCas9	negative selection	6561162
67645709	67645732	11	+	27260156	CORL105	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.2538345777881584	[541]	[699,428,541,466]	-5	hSpCas9	negative selection	6561163
67644808	67644831	11	+	27260156	HS294T	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.5300161021088615	[205]	[41,64,278,75]	7	hSpCas9	negative selection	6618129
67644816	67644839	11	-	27260156	HS294T	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.11278343261897117	[262]	[46,154,73,103]	-1	hSpCas9	negative selection	6618130
67642802	67642825	11	+	27260156	HS294T	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.16009440200388997	[434]	[96,312,125,225]	2	hSpCas9	negative selection	6618131
67645330	67645353	11	-	27260156	HS294T	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.18154983772973537	[623]	[278,247,232,345]	2	hSpCas9	negative selection	6682412
67645852	67645875	11	+	27260156	HS294T	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.221418647598659	[464]	[195,116,133,168]	-3	hSpCas9	negative selection	6682413
67645709	67645732	11	+	27260156	HS294T	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.7204135294108793	[541]	[108,109,127,170]	-8	hSpCas9	negative selection	6682414
67644808	67644831	11	+	27260156	HCC44	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3353174761203065	[205]	[339,327,301,206]	5	hSpCas9	negative selection	6739380
67644816	67644839	11	-	27260156	HCC44	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.03994249389822446	[262]	[227,270,420,317]	0	hSpCas9	negative selection	6739381
67642802	67642825	11	+	27260156	HCC44	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.4117926266974636	[434]	[694,370,861,760]	6	hSpCas9	negative selection	6739382
67645330	67645353	11	-	27260156	HCC44	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.13886633528263898	[623]	[1012,370,1085,764]	2	hSpCas9	negative selection	6803663
67645852	67645875	11	+	27260156	HCC44	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.3715342918436405	[464]	[1020,661,558,492]	6	hSpCas9	negative selection	6803664
67645709	67645732	11	+	27260156	HCC44	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.5278983121424681	[541]	[487,388,416,412]	-7	hSpCas9	negative selection	6803665
67644808	67644831	11	+	27260156	G402	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.07310079815554937	[205]	[413,353,167,152]	0	hSpCas9	negative selection	6860631
67644816	67644839	11	-	27260156	G402	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.036220462037664714	[262]	[334,406,325,196]	0	hSpCas9	negative selection	6860632
67642802	67642825	11	+	27260156	G402	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.021837753381448333	[434]	[564,634,618,352]	0	hSpCas9	negative selection	6860633
67645330	67645353	11	-	27260156	G402	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.4701377552503703	[623]	[469,1016,341,390]	-5	hSpCas9	negative selection	6924914
67645852	67645875	11	+	27260156	G402	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.14771199945979763	[464]	[999,557,663,352]	1	hSpCas9	negative selection	6924915
67645709	67645732	11	+	27260156	G402	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.8395891822103123	[541]	[444,310,436,294]	-7	hSpCas9	negative selection	6924916
67644808	67644831	11	+	27260156	L33	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.09090548005338239	[205]	[204,81,165,208]	2	hSpCas9	negative selection	6981882
67644816	67644839	11	-	27260156	L33	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.03275569932791367	[262]	[270,99,145,327]	0	hSpCas9	negative selection	6981883
67642802	67642825	11	+	27260156	L33	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.28215050906387185	[434]	[499,192,381,537]	6	hSpCas9	negative selection	6981884
67645330	67645353	11	-	27260156	L33	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.06768191739684026	[623]	[605,290,424,624]	1	hSpCas9	negative selection	7046165
67645852	67645875	11	+	27260156	L33	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.13971280571466768	[464]	[419,178,278,387]	-3	hSpCas9	negative selection	7046166
67645709	67645732	11	+	27260156	L33	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.08105323832210863	[541]	[451,226,299,566]	-2	hSpCas9	negative selection	7046167
67644808	67644831	11	+	27260156	K562	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.008604755005496179	[205]	[265,173,97,200]	0	hSpCas9	negative selection	7103133
67644816	67644839	11	-	27260156	K562	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.1841445960221988	[262]	[427,341,202,120]	2	hSpCas9	negative selection	7103134
67642802	67642825	11	+	27260156	K562	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.5692220809668413	[434]	[485,547,680,565]	7	hSpCas9	negative selection	7103135
67645330	67645353	11	-	27260156	K562	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.2104323355264897	[623]	[449,1046,523,554]	2	hSpCas9	negative selection	7167416
67645852	67645875	11	+	27260156	K562	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.6270910153281964	[464]	[375,314,214,182]	-6	hSpCas9	negative selection	7167417
67645709	67645732	11	+	27260156	K562	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	0.5156387003033387	[541]	[1127,642,319,689]	6	hSpCas9	negative selection	7167418
67644808	67644831	11	+	27260156	HT29	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.09777330825424957	[205]	[255,272,226,188]	-2	hSpCas9	negative selection	7224384
67644816	67644839	11	-	27260156	HT29	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.7515258203735793	[262]	[145,255,199,161]	-8	hSpCas9	negative selection	7224385
67642802	67642825	11	+	27260156	HT29	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.2724317646469469	[434]	[822,515,667,556]	5	hSpCas9	negative selection	7224386
67645330	67645353	11	-	27260156	HT29	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.15979235222388838	[623]	[1076,1014,678,666]	3	hSpCas9	negative selection	7288667
67645852	67645875	11	+	27260156	HT29	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.21246532863971673	[464]	[437,628,444,448]	-4	hSpCas9	negative selection	7288668
67645709	67645732	11	+	27260156	HT29	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.29717477836788664	[541]	[467,759,606,343]	-5	hSpCas9	negative selection	7288669
67644808	67644831	11	+	27260156	MHHES1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.6077647918448611	[205]	[318,331,400,348]	9	hSpCas9	negative selection	7345635
67644816	67644839	11	-	27260156	MHHES1	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.2631979545635279	[262]	[150,216,359,240]	-5	hSpCas9	negative selection	7345636
67642802	67642825	11	+	27260156	MHHES1	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.12277439874092068	[434]	[569,656,572,375]	2	hSpCas9	negative selection	7345637
67645330	67645353	11	-	27260156	MHHES1	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.13779601176587786	[623]	[928,585,523,550]	-3	hSpCas9	negative selection	7409918
67645852	67645875	11	+	27260156	MHHES1	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.002348270652137439	[464]	[946,511,476,261]	0	hSpCas9	negative selection	7409919
67645709	67645732	11	+	27260156	MHHES1	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.38830842977506735	[541]	[414,526,544,386]	-6	hSpCas9	negative selection	7409920
67644808	67644831	11	+	27260156	MEWO	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.718991049560983	[205]	[441,275,257]	9	hSpCas9	negative selection	7466886
67644816	67644839	11	-	27260156	MEWO	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.0016888935129414362	[262]	[408,139,221]	0	hSpCas9	negative selection	7466887
67642802	67642825	11	+	27260156	MEWO	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.39998801443157533	[434]	[700,462,478]	8	hSpCas9	negative selection	7466888
67645330	67645353	11	-	27260156	MEWO	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.17720515518272545	[623]	[814,685,508]	4	hSpCas9	negative selection	7531169
67645852	67645875	11	+	27260156	MEWO	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.009626720918427915	[464]	[437,527,330]	0	hSpCas9	negative selection	7531170
67645709	67645732	11	+	27260156	MEWO	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	0.1512680174647691	[541]	[783,368,579]	3	hSpCas9	negative selection	7531171
67644808	67644831	11	+	27260156	LNCAPCLONEFGC	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3377840914693654	[205]	[281,183,257,224]	5	hSpCas9	negative selection	7588137
67644816	67644839	11	-	27260156	LNCAPCLONEFGC	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.09506370155760313	[262]	[356,227,210,214]	1	hSpCas9	negative selection	7588138
67642802	67642825	11	+	27260156	LNCAPCLONEFGC	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.3914994449716957	[434]	[494,537,649,402]	6	hSpCas9	negative selection	7588139
67645330	67645353	11	-	27260156	LNCAPCLONEFGC	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.11460007825103985	[623]	[621,813,591,402]	1	hSpCas9	negative selection	7652420
67645852	67645875	11	+	27260156	LNCAPCLONEFGC	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.023479752121767093	[464]	[346,426,475,470]	0	hSpCas9	negative selection	7652421
67645709	67645732	11	+	27260156	LNCAPCLONEFGC	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.044981990862092175	[541]	[422,349,693,477]	0	hSpCas9	negative selection	7652422
67644808	67644831	11	+	27260156	PANC0327	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.7364551466096015	[205]	[657,142,149,317]	9	hSpCas9	negative selection	7709388
67644816	67644839	11	-	27260156	PANC0327	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.13931575003824104	[262]	[168,357,156,141]	-2	hSpCas9	negative selection	7709389
67642802	67642825	11	+	27260156	PANC0327	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.3402599775991908	[434]	[514,416,477,557]	5	hSpCas9	negative selection	7709390
67645330	67645353	11	-	27260156	PANC0327	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.08681469496402572	[623]	[345,815,446,695]	1	hSpCas9	negative selection	7773671
67645852	67645875	11	+	27260156	PANC0327	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.200701072542899	[464]	[344,479,336,724]	3	hSpCas9	negative selection	7773672
67645709	67645732	11	+	27260156	PANC0327	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.5958703299772692	[541]	[455,221,368,250]	-7	hSpCas9	negative selection	7773673
67644808	67644831	11	+	27260156	NCIH2009	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.44419793738748825	[205]	[472,346,370]	6	hSpCas9	negative selection	7830639
67644816	67644839	11	-	27260156	NCIH2009	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.029362060337053797	[262]	[514,313,281]	0	hSpCas9	negative selection	7830640
67642802	67642825	11	+	27260156	NCIH2009	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.15746650411077243	[434]	[718,762,556]	2	hSpCas9	negative selection	7830641
67645330	67645353	11	-	27260156	NCIH2009	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.0577749494385737	[623]	[1052,938,756]	0	hSpCas9	negative selection	7894922
67645852	67645875	11	+	27260156	NCIH2009	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.08658402052601152	[464]	[922,554,418]	-1	hSpCas9	negative selection	7894923
67645709	67645732	11	+	27260156	NCIH2009	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	0.24715725841684943	[541]	[1180,708,863]	3	hSpCas9	negative selection	7894924
67644808	67644831	11	+	27260156	NCIH1373	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.5668633011767803	[205]	[94,92,150,75]	-5	hSpCas9	negative selection	7951890
67644816	67644839	11	-	27260156	NCIH1373	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.21278965052416066	[262]	[160,247,199,105]	-2	hSpCas9	negative selection	7951891
67642802	67642825	11	+	27260156	NCIH1373	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.6890921713726736	[434]	[575,595,1037,241]	7	hSpCas9	negative selection	7951892
67645330	67645353	11	-	27260156	NCIH1373	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.1860985716846189	[623]	[640,1147,550,204]	1	hSpCas9	negative selection	8016173
67645852	67645875	11	+	27260156	NCIH1373	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.08523954239692162	[464]	[1142,257,336,90]	-1	hSpCas9	negative selection	8016174
67645709	67645732	11	+	27260156	NCIH1373	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.32698953934483727	[541]	[450,309,674,133]	-3	hSpCas9	negative selection	8016175
67644808	67644831	11	+	27260156	PATU8902	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.08041053519458763	[205]	[103,433,237,324]	-1	hSpCas9	negative selection	8073141
67644816	67644839	11	-	27260156	PATU8902	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.5348977881183361	[262]	[489,111,126,316]	-5	hSpCas9	negative selection	8073142
67642802	67642825	11	+	27260156	PATU8902	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.6591606716282975	[434]	[502,584,82,444]	-6	hSpCas9	negative selection	8073143
67645330	67645353	11	-	27260156	PATU8902	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.4026884664484095	[623]	[645,426,672,902]	-4	hSpCas9	negative selection	8137424
67645852	67645875	11	+	27260156	PATU8902	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.013043635645255278	[464]	[791,902,525,387]	0	hSpCas9	negative selection	8137425
67645709	67645732	11	+	27260156	PATU8902	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.06555990422144117	[541]	[620,766,235,1472]	0	hSpCas9	negative selection	8137426
67644808	67644831	11	+	27260156	PANC1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.1574563212249116	[205]	[223,153,138,118]	-3	hSpCas9	negative selection	8194392
67644816	67644839	11	-	27260156	PANC1	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.5653286614048223	[262]	[375,505,324,183]	8	hSpCas9	negative selection	8194393
67642802	67642825	11	+	27260156	PANC1	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.29890864938435385	[434]	[508,525,397,416]	5	hSpCas9	negative selection	8194394
67645330	67645353	11	-	27260156	PANC1	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.16052680054621166	[623]	[734,709,426,541]	2	hSpCas9	negative selection	8258675
67645852	67645875	11	+	27260156	PANC1	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.08342820225663515	[464]	[559,591,338,253]	1	hSpCas9	negative selection	8258676
67645709	67645732	11	+	27260156	PANC1	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.16906476249064414	[541]	[346,512,509,317]	-3	hSpCas9	negative selection	8258677
67644808	67644831	11	+	27260156	PANC0813	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.4571305372035632	[205]	[285,181,456,395]	7	hSpCas9	negative selection	8315643
67644816	67644839	11	-	27260156	PANC0813	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.223601373705264	[262]	[388,307,351,393]	3	hSpCas9	negative selection	8315644
67642802	67642825	11	+	27260156	PANC0813	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.0021939882916111875	[434]	[650,391,671,347]	0	hSpCas9	negative selection	8315645
67645330	67645353	11	-	27260156	PANC0813	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.023984207080526843	[623]	[853,671,692,677]	0	hSpCas9	negative selection	8379926
67645852	67645875	11	+	27260156	PANC0813	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.2551356495880104	[464]	[552,466,458,364]	-4	hSpCas9	negative selection	8379927
67645709	67645732	11	+	27260156	PANC0813	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.336907808948834	[541]	[406,568,654,382]	-5	hSpCas9	negative selection	8379928
67644808	67644831	11	+	27260156	RDES	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.23174821855982297	[205]	[267,263,279,297]	4	hSpCas9	negative selection	8436894
67644816	67644839	11	-	27260156	RDES	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.5179626844177678	[262]	[152,214,188,307]	-7	hSpCas9	negative selection	8436895
67642802	67642825	11	+	27260156	RDES	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.14489631726896074	[434]	[458,350,465,540]	-2	hSpCas9	negative selection	8436896
67645330	67645353	11	-	27260156	RDES	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.050365482987979215	[623]	[646,479,840,840]	-1	hSpCas9	negative selection	8501177
67645852	67645875	11	+	27260156	RDES	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.027029913319046348	[464]	[394,538,549,645]	0	hSpCas9	negative selection	8501178
67645709	67645732	11	+	27260156	RDES	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.49918709116570137	[541]	[378,442,468,478]	-7	hSpCas9	negative selection	8501179
67644808	67644831	11	+	27260156	PC3	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.11535284227971498	[205]	[167,200,230,155]	-3	hSpCas9	negative selection	8558145
67644816	67644839	11	-	27260156	PC3	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.13850273266699342	[262]	[197,210,399,193]	-3	hSpCas9	negative selection	8558146
67642802	67642825	11	+	27260156	PC3	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.39434181726116796	[434]	[476,577,803,474]	8	hSpCas9	negative selection	8558147
67645330	67645353	11	-	27260156	PC3	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.4720500059924175	[623]	[601,1009,1136,817]	8	hSpCas9	negative selection	8622428
67645852	67645875	11	+	27260156	PC3	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.2780545793912098	[464]	[254,314,648,436]	-6	hSpCas9	negative selection	8622429
67645709	67645732	11	+	27260156	PC3	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.246472767444744	[541]	[338,342,784,490]	-5	hSpCas9	negative selection	8622430
67644808	67644831	11	+	27260156	PATU8988T	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	1.0377036740023529	[205]	[226,514,319,598]	9	hSpCas9	negative selection	8679396
67644816	67644839	11	-	27260156	PATU8988T	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.14639766321277037	[262]	[296,257,401,153]	2	hSpCas9	negative selection	8679397
67642802	67642825	11	+	27260156	PATU8988T	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.2971750388782072	[434]	[375,530,538,629]	5	hSpCas9	negative selection	8679398
67645330	67645353	11	-	27260156	PATU8988T	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.2954916571633495	[623]	[992,799,522,644]	5	hSpCas9	negative selection	8743679
67645852	67645875	11	+	27260156	PATU8988T	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.18891890081066107	[464]	[599,325,234,412]	-3	hSpCas9	negative selection	8743680
67645709	67645732	11	+	27260156	PATU8988T	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.008991835550134691	[541]	[388,504,735,440]	0	hSpCas9	negative selection	8743681
67644808	67644831	11	+	27260156	T47D	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.29327228676381156	[205]	[280,253,304,340]	6	hSpCas9	negative selection	8800647
67644816	67644839	11	-	27260156	T47D	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.03423995788953205	[262]	[340,311,299,301]	0	hSpCas9	negative selection	8800648
67642802	67642825	11	+	27260156	T47D	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.12928554016300153	[434]	[544,498,553,625]	2	hSpCas9	negative selection	8800649
67645330	67645353	11	-	27260156	T47D	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.00408970788297075	[623]	[719,662,705,818]	0	hSpCas9	negative selection	8864930
67645852	67645875	11	+	27260156	T47D	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.19635425791165156	[464]	[474,391,550,478]	-4	hSpCas9	negative selection	8864931
67645709	67645732	11	+	27260156	T47D	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.37488247126172236	[541]	[607,383,481,482]	-7	hSpCas9	negative selection	8864932
67644808	67644831	11	+	27260156	SU8686	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.14057114255802672	[205]	[200,271,175,248]	2	hSpCas9	negative selection	8921898
67644816	67644839	11	-	27260156	SU8686	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	0.2633378606611929	[262]	[334,264,309,348]	4	hSpCas9	negative selection	8921899
67642802	67642825	11	+	27260156	SU8686	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.21212867575053657	[434]	[477,421,543,576]	3	hSpCas9	negative selection	8921900
67645330	67645353	11	-	27260156	SU8686	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.06333771961359891	[623]	[602,554,709,747]	1	hSpCas9	negative selection	8986181
67645852	67645875	11	+	27260156	SU8686	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.08707026643695813	[464]	[466,391,414,464]	-1	hSpCas9	negative selection	8986182
67645709	67645732	11	+	27260156	SU8686	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.29929935957412646	[541]	[347,513,405,481]	-5	hSpCas9	negative selection	8986183
67644808	67644831	11	+	27260156	SKES1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.4791775274507619	[205]	[257,394,287,218]	8	hSpCas9	negative selection	9043149
67644816	67644839	11	-	27260156	SKES1	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.12714310098715442	[262]	[250,195,223,278]	-3	hSpCas9	negative selection	9043150
67642802	67642825	11	+	27260156	SKES1	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.2876095223920532	[434]	[558,621,536,422]	6	hSpCas9	negative selection	9043151
67645330	67645353	11	-	27260156	SKES1	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.04492765463277548	[623]	[797,670,518,604]	1	hSpCas9	negative selection	9107432
67645852	67645875	11	+	27260156	SKES1	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.010040122048606152	[464]	[465,445,600,358]	0	hSpCas9	negative selection	9107433
67645709	67645732	11	+	27260156	SKES1	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.06435900515789039	[541]	[490,510,412,630]	-1	hSpCas9	negative selection	9107434
67644808	67644831	11	+	27260156	TOV112D	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.24378366072228053	[205]	[180,172,206,136]	-5	hSpCas9	negative selection	9164400
67644816	67644839	11	-	27260156	TOV112D	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.44843272641570775	[262]	[164,408,105,143]	-7	hSpCas9	negative selection	9164401
67642802	67642825	11	+	27260156	TOV112D	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.3392465380971209	[434]	[452,793,483,524]	6	hSpCas9	negative selection	9164402
67645330	67645353	11	-	27260156	TOV112D	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	-0.09869062667813805	[623]	[605,704,638,419]	-2	hSpCas9	negative selection	9228683
67645852	67645875	11	+	27260156	TOV112D	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.2522990268448735	[464]	[367,587,302,351]	-5	hSpCas9	negative selection	9228684
67645709	67645732	11	+	27260156	TOV112D	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.2639811009302092	[541]	[548,626,239,442]	-5	hSpCas9	negative selection	9228685
67644808	67644831	11	+	27260156	TC71	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.24413714031286682	[205]	[233,258,258,296]	6	hSpCas9	negative selection	9285651
67644816	67644839	11	-	27260156	TC71	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.056821569332355826	[262]	[259,238,262,325]	-1	hSpCas9	negative selection	9285652
67642802	67642825	11	+	27260156	TC71	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	0.27717409788496833	[434]	[446,625,512,685]	6	hSpCas9	negative selection	9285653
67645330	67645353	11	-	27260156	TC71	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.11505708083219685	[623]	[651,837,690,718]	3	hSpCas9	negative selection	9349934
67645852	67645875	11	+	27260156	TC71	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	-0.2436648754310097	[464]	[419,408,418,436]	-6	hSpCas9	negative selection	9349935
67645709	67645732	11	+	27260156	TC71	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.11000649772707444	[541]	[449,524,548,636]	-3	hSpCas9	negative selection	9349936
67644808	67644831	11	+	27260156	TC32	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.2717541083531536	[205]	[167,121,437,283]	5	hSpCas9	negative selection	9406902
67644816	67644839	11	-	27260156	TC32	viability	CTATAGACCCGTGGGCGTCGTGG	ACY3	ENSG00000132744	-0.18455235296356887	[262]	[116,187,282,309]	-3	hSpCas9	negative selection	9406903
67642802	67642825	11	+	27260156	TC32	viability	GGCAACGCCCTTCTCATAGTAGG	ACY3	ENSG00000132744	-0.0621585042081325	[434]	[286,286,541,513]	-1	hSpCas9	negative selection	9406904
67645330	67645353	11	-	27260156	TC32	viability	TCTTCCTGTACCAGCGGTCTGGG	ACY3	ENSG00000132744	0.18424644958265574	[623]	[544,728,750,597]	3	hSpCas9	negative selection	9471185
67645852	67645875	11	+	27260156	TC32	viability	GTCACCTCATATGGGTCGTCCGG	ACY3	ENSG00000132744	0.2646191549604814	[464]	[396,490,798,452]	5	hSpCas9	negative selection	9471186
67645709	67645732	11	+	27260156	TC32	viability	GGTGCATGGCAAAGACTTCGTGG	ACY3	ENSG00000132744	-0.2796259673762744	[541]	[273,310,707,474]	-5	hSpCas9	negative selection	9471187
67642824	67642847	11	+	27869803	HPAFII	viability after 27 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	0.3692502542892071	[282]	[105,263,NaN]	3	hSpCas9	negative selection	9543620
67644843	67644866	11	-	27869803	HPAFII	viability after 27 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.7880435334732403	[70]	[76,53,NaN]	6	hSpCas9	negative selection	9543621
67645084	67645107	11	-	27869803	HPAFII	viability after 27 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.9404480499826083	[148]	[66,18,NaN]	-6	hSpCas9	negative selection	9543622
67645731	67645754	11	+	27869803	HPAFII	viability after 27 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.2241263984304156	[195]	[109,128,NaN]	1	hSpCas9	negative selection	9543623
67646839	67646862	11	+	27869803	HPAFII	viability after 27 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.3120899583925798	[195]	[148,27,NaN]	-2	hSpCas9	negative selection	9543624
67646993	67647016	11	+	27869803	HPAFII	viability after 27 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.35476703632066353	[214]	[71,204,NaN]	3	hSpCas9	negative selection	9543625
67642824	67642847	11	+	27869803	HPAFII	viability after 15 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	0.022541758539279116	[282]	[184,385,NaN]	0	hSpCas9	negative selection	9626069
67644843	67644866	11	-	27869803	HPAFII	viability after 15 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.7734617267789341	[70]	[143,121,NaN]	8	hSpCas9	negative selection	9626070
67645084	67645107	11	-	27869803	HPAFII	viability after 15 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.3843009437277053	[148]	[163,96,NaN]	-4	hSpCas9	negative selection	9626071
67645731	67645754	11	+	27869803	HPAFII	viability after 15 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.2791872677742846	[195]	[188,163,NaN]	-3	hSpCas9	negative selection	9626072
67646839	67646862	11	+	27869803	HPAFII	viability after 15 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.4931487955258499	[195]	[243,90,NaN]	-5	hSpCas9	negative selection	9626073
67646993	67647016	11	+	27869803	HPAFII	viability after 15 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.3514705409575062	[214]	[390,234,NaN]	4	hSpCas9	negative selection	9626074
67642824	67642847	11	+	27869803	ASPC1	viability after 36 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-1.1495791553037136	[647]	[199,23,93]	-8	hSpCas9	negative selection	9708518
67644843	67644866	11	-	27869803	ASPC1	viability after 36 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	-0.3492420811368684	[274]	[98,97,39]	-4	hSpCas9	negative selection	9708519
67645084	67645107	11	-	27869803	ASPC1	viability after 36 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.29648427894345053	[243]	[94,83,38]	-3	hSpCas9	negative selection	9708520
67645731	67645754	11	+	27869803	ASPC1	viability after 36 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.8260310807426579	[369]	[245,99,316]	7	hSpCas9	negative selection	9708521
67646839	67646862	11	+	27869803	ASPC1	viability after 36 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-1.4771403536684053	[333]	[63,37,28]	-8	hSpCas9	negative selection	9708522
67646993	67647016	11	+	27869803	ASPC1	viability after 36 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.5536131251618917	[682]	[471,157,412]	5	hSpCas9	negative selection	9708523
67642824	67642847	11	+	27869803	PATU8988S	viability after 35 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-1.2058719206452775	[566]	[96,100,NaN]	-8	hSpCas9	negative selection	9790967
67644843	67644866	11	-	27869803	PATU8988S	viability after 35 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.3213515065755508	[138]	[47,91,NaN]	3	hSpCas9	negative selection	9790968
67645084	67645107	11	-	27869803	PATU8988S	viability after 35 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.568887032016421	[207]	[44,67,NaN]	-5	hSpCas9	negative selection	9790969
67645731	67645754	11	+	27869803	PATU8988S	viability after 35 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.40394518647412414	[344]	[111,97,NaN]	-4	hSpCas9	negative selection	9790970
67646839	67646862	11	+	27869803	PATU8988S	viability after 35 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.5989606946176615	[314]	[300,467,NaN]	9	hSpCas9	negative selection	9790971
67646993	67647016	11	+	27869803	PATU8988S	viability after 35 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	-0.33599351632250407	[502]	[157,162,NaN]	-4	hSpCas9	negative selection	9790972
67642824	67642847	11	+	27869803	PATU8988S	viability after 31 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	-0.9429545386245175	[566]	[132,97,NaN]	-7	hSpCas9	negative selection	9873416
67644843	67644866	11	-	27869803	PATU8988S	viability after 31 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.33348716213010277	[138]	[64,75,NaN]	4	hSpCas9	negative selection	9873417
67645084	67645107	11	-	27869803	PATU8988S	viability after 31 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.057206136919504935	[207]	[51,114,NaN]	0	hSpCas9	negative selection	9873418
67645731	67645754	11	+	27869803	PATU8988S	viability after 31 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.3182415370640759	[344]	[167,175,NaN]	4	hSpCas9	negative selection	9873419
67646839	67646862	11	+	27869803	PATU8988S	viability after 31 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.4807957893826111	[314]	[178,568,NaN]	9	hSpCas9	negative selection	9873420
67646993	67647016	11	+	27869803	PATU8988S	viability after 31 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.010247889170092228	[502]	[190,215,NaN]	0	hSpCas9	negative selection	9873421
67642824	67642847	11	+	27869803	HPAFII	viability after 35 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	0.21857139047853463	[282]	[42,305,NaN]	1	hSpCas9	negative selection	9955865
67644843	67644866	11	-	27869803	HPAFII	viability after 35 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	-0.2105221047208734	[70]	[39,20,NaN]	-1	hSpCas9	negative selection	9955866
67645084	67645107	11	-	27869803	HPAFII	viability after 35 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-2.2911851027621606	[148]	[13,16,NaN]	-8	hSpCas9	negative selection	9955867
67645731	67645754	11	+	27869803	HPAFII	viability after 35 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	-0.3191287791973777	[195]	[87,69,NaN]	-2	hSpCas9	negative selection	9955868
67646839	67646862	11	+	27869803	HPAFII	viability after 35 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.025138449474217783	[195]	[155,38,NaN]	0	hSpCas9	negative selection	9955869
67646993	67647016	11	+	27869803	HPAFII	viability after 35 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.2543321974847433	[214]	[15,257,NaN]	1	hSpCas9	negative selection	9955870
67642824	67642847	11	+	27869803	HPAFII	viability after 31 days	GCAGCCTCGTTAATGAACACGGG	ACY3	ENSG00000132744	0.04689317616369512	[282]	[53,283,NaN]	0	hSpCas9	negative selection	10038314
67644843	67644866	11	-	27869803	HPAFII	viability after 31 days	GGCCTTTCCTGCCTTTGAGATGG	ACY3	ENSG00000132744	0.05169395670265864	[70]	[47,33,NaN]	0	hSpCas9	negative selection	10038315
67645084	67645107	11	-	27869803	HPAFII	viability after 31 days	TTTCTCAAGGATGAGGACCCTGG	ACY3	ENSG00000132744	-0.6196943978333648	[148]	[74,31,NaN]	-4	hSpCas9	negative selection	10038316
67645731	67645754	11	+	27869803	HPAFII	viability after 31 days	GGAGGACTTCGCGATTAAGCAGG	ACY3	ENSG00000132744	0.33871404645147707	[195]	[107,172,NaN]	2	hSpCas9	negative selection	10038317
67646839	67646862	11	+	27869803	HPAFII	viability after 31 days	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.8946839880756914	[195]	[73,42,NaN]	-5	hSpCas9	negative selection	10038318
67646993	67647016	11	+	27869803	HPAFII	viability after 31 days	AGTCACAGCCACGCGACGCAGGG	ACY3	ENSG00000132744	0.21703531069459048	[214]	[22,267,NaN]	1	hSpCas9	negative selection	10038319
67646839	67646862	11	+	28162770	P31FUJ	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.2743214738526454	[140]	[136]	-3	hSpCas9	negative selection	10106672
67644808	67644831	11	+	28162770	P31FUJ	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.13306923806058069	[96]	[124]	1	hSpCas9	negative selection	10106673
67645749	67645772	11	+	28162770	P31FUJ	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.7812729807973442	[152]	[308]	8	hSpCas9	negative selection	10106674
67645110	67645133	11	+	28162770	P31FUJ	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.12538943445975526	[439]	[563]	1	hSpCas9	negative selection	10106675
67646994	67647017	11	+	28162770	P31FUJ	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.4850545668041229	[151]	[249]	5	hSpCas9	negative selection	10106676
67645821	67645844	11	-	28162770	P31FUJ	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.309990842062838	[161]	[235]	3	hSpCas9	negative selection	10106677
67645336	67645359	11	-	28162770	P31FUJ	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.13621712594656898	[867]	[1120]	1	hSpCas9	negative selection	10106678
67644825	67644848	11	-	28162770	P31FUJ	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.021072202133939344	[394]	[470]	0	hSpCas9	negative selection	10106679
67646882	67646905	11	+	28162770	P31FUJ	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.4676375137267136	[183]	[298]	5	hSpCas9	negative selection	10106680
67646852	67646875	11	+	28162770	P31FUJ	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-2.2328022044143783	[3]	[0]	-8	hSpCas9	negative selection	10106681
67646839	67646862	11	+	28162770	TF1	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10276038
67644808	67644831	11	+	28162770	TF1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10276039
67645749	67645772	11	+	28162770	TF1	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10276040
67645110	67645133	11	+	28162770	TF1	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10276041
67646994	67647017	11	+	28162770	TF1	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10276042
67645821	67645844	11	-	28162770	TF1	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10276043
67645336	67645359	11	-	28162770	TF1	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	NaN	[NaN]	[335]	1	hSpCas9	negative selection	10276044
67644825	67644848	11	-	28162770	TF1	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10276045
67646882	67646905	11	+	28162770	TF1	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10276046
67646852	67646875	11	+	28162770	TF1	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10276047
67646839	67646862	11	+	28162770	SKM1	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.30352918406185353	[54]	[119]	3	hSpCas9	negative selection	10445404
67644808	67644831	11	+	28162770	SKM1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.32483969030726567	[27]	[61]	3	hSpCas9	negative selection	10445405
67645749	67645772	11	+	28162770	SKM1	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.7915299548959215	[49]	[152]	7	hSpCas9	negative selection	10445406
67645110	67645133	11	+	28162770	SKM1	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	-0.18937276367053468	[128]	[199]	-2	hSpCas9	negative selection	10445407
67646994	67647017	11	+	28162770	SKM1	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	-0.11305048002539601	[51]	[84]	-1	hSpCas9	negative selection	10445408
67645821	67645844	11	-	28162770	SKM1	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.043980954006306944	[61]	[112]	0	hSpCas9	negative selection	10445409
67645336	67645359	11	-	28162770	SKM1	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	1.167429060267807	[136]	[543]	9	hSpCas9	negative selection	10445410
67644825	67644848	11	-	28162770	SKM1	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.6817647198511698	[66]	[189]	6	hSpCas9	negative selection	10445411
67646882	67646905	11	+	28162770	SKM1	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.08946162737633717	[41]	[78]	0	hSpCas9	negative selection	10445412
67646852	67646875	11	+	28162770	SKM1	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10445413
67646839	67646862	11	+	28162770	SKM1	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.30352918406185353	[54]	[119]	3	hSpCas9	negative selection	10614770
67644808	67644831	11	+	28162770	SKM1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.32483969030726567	[27]	[61]	3	hSpCas9	negative selection	10614771
67645749	67645772	11	+	28162770	SKM1	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.7915299548959215	[49]	[152]	7	hSpCas9	negative selection	10614772
67645110	67645133	11	+	28162770	SKM1	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	-0.18937276367053468	[128]	[199]	-2	hSpCas9	negative selection	10614773
67646994	67647017	11	+	28162770	SKM1	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	-0.11305048002539601	[51]	[84]	-1	hSpCas9	negative selection	10614774
67645821	67645844	11	-	28162770	SKM1	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.043980954006306944	[61]	[112]	0	hSpCas9	negative selection	10614775
67645336	67645359	11	-	28162770	SKM1	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	1.167429060267807	[136]	[543]	9	hSpCas9	negative selection	10614776
67644825	67644848	11	-	28162770	SKM1	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.6817647198511698	[66]	[189]	6	hSpCas9	negative selection	10614777
67646882	67646905	11	+	28162770	SKM1	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.08946162737633717	[41]	[78]	0	hSpCas9	negative selection	10614778
67646852	67646875	11	+	28162770	SKM1	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10614779
67646839	67646862	11	+	28162770	PL21	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.24320833638120615	[131]	[67]	2	hSpCas9	negative selection	10784136
67644808	67644831	11	+	28162770	PL21	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.7731294735444003	[120]	[89]	6	hSpCas9	negative selection	10784137
67645749	67645772	11	+	28162770	PL21	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	1.9814993280139799	[159]	[274]	9	hSpCas9	negative selection	10784138
67645110	67645133	11	+	28162770	PL21	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.8685613495682384	[374]	[297]	7	hSpCas9	negative selection	10784139
67646994	67647017	11	+	28162770	PL21	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.035080368218823876	[147]	[65]	0	hSpCas9	negative selection	10784140
67645821	67645844	11	-	28162770	PL21	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.35768089147580023	[259]	[144]	3	hSpCas9	negative selection	10784141
67645336	67645359	11	-	28162770	PL21	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.14443018190303247	[527]	[253]	1	hSpCas9	negative selection	10784142
67644825	67644848	11	-	28162770	PL21	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.2803717222668051	[292]	[104]	-2	hSpCas9	negative selection	10784143
67646882	67646905	11	+	28162770	PL21	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-0.025741792927007734	[137]	[58]	0	hSpCas9	negative selection	10784144
67646852	67646875	11	+	28162770	PL21	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-1.3848228862318361	[5]	[0]	-7	hSpCas9	negative selection	10784145
67646839	67646862	11	+	28162770	P31FUJ	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.2743214738526454	[140]	[136]	-3	hSpCas9	negative selection	10953502
67644808	67644831	11	+	28162770	P31FUJ	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.13306923806058069	[96]	[124]	1	hSpCas9	negative selection	10953503
67645749	67645772	11	+	28162770	P31FUJ	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.7812729807973442	[152]	[308]	8	hSpCas9	negative selection	10953504
67645110	67645133	11	+	28162770	P31FUJ	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.12538943445975526	[439]	[563]	1	hSpCas9	negative selection	10953505
67646994	67647017	11	+	28162770	P31FUJ	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.4850545668041229	[151]	[249]	5	hSpCas9	negative selection	10953506
67645821	67645844	11	-	28162770	P31FUJ	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.309990842062838	[161]	[235]	3	hSpCas9	negative selection	10953507
67645336	67645359	11	-	28162770	P31FUJ	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.13621712594656898	[867]	[1120]	1	hSpCas9	negative selection	10953508
67644825	67644848	11	-	28162770	P31FUJ	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.021072202133939344	[394]	[470]	0	hSpCas9	negative selection	10953509
67646882	67646905	11	+	28162770	P31FUJ	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.4676375137267136	[183]	[298]	5	hSpCas9	negative selection	10953510
67646852	67646875	11	+	28162770	P31FUJ	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-2.2328022044143783	[3]	[0]	-8	hSpCas9	negative selection	10953511
67646839	67646862	11	+	28162770	OCIAML5	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.5319832359311628	[99]	[260]	4	hSpCas9	negative selection	11122868
67644808	67644831	11	+	28162770	OCIAML5	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.8169601946456337	[49]	[158]	7	hSpCas9	negative selection	11122869
67645749	67645772	11	+	28162770	OCIAML5	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	1.2702238589394308	[64]	[282]	9	hSpCas9	negative selection	11122870
67645110	67645133	11	+	28162770	OCIAML5	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.49638781853355307	[193]	[493]	4	hSpCas9	negative selection	11122871
67646994	67647017	11	+	28162770	OCIAML5	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.3178584305783154	[91]	[206]	2	hSpCas9	negative selection	11122872
67645821	67645844	11	-	28162770	OCIAML5	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	1.311679855649191	[103]	[465]	9	hSpCas9	negative selection	11122873
67645336	67645359	11	-	28162770	OCIAML5	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.471463628619867	[359]	[900]	4	hSpCas9	negative selection	11122874
67644825	67644848	11	-	28162770	OCIAML5	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.5506225359872019	[131]	[348]	5	hSpCas9	negative selection	11122875
67646882	67646905	11	+	28162770	OCIAML5	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.30078491721937406	[84]	[188]	2	hSpCas9	negative selection	11122876
67646852	67646875	11	+	28162770	OCIAML5	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	1.732895929857159	[2]	[17]	9	hSpCas9	negative selection	11122877
67646839	67646862	11	+	28162770	EOL1	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.045499006327837516	[285]	[145]	0	hSpCas9	negative selection	11292234
67644808	67644831	11	+	28162770	EOL1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.3196857134116734	[145]	[95]	3	hSpCas9	negative selection	11292235
67645749	67645772	11	+	28162770	EOL1	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.985774570820981	[345]	[360]	8	hSpCas9	negative selection	11292236
67645110	67645133	11	+	28162770	EOL1	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.5567571507885241	[790]	[612]	5	hSpCas9	negative selection	11292237
67646994	67647017	11	+	28162770	EOL1	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	-0.29148915472608977	[301]	[129]	-2	hSpCas9	negative selection	11292238
67645821	67645844	11	-	28162770	EOL1	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.7172605895553315	[439]	[140]	-5	hSpCas9	negative selection	11292239
67645336	67645359	11	-	28162770	EOL1	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.6430118654841293	[721]	[593]	6	hSpCas9	negative selection	11292240
67644825	67644848	11	-	28162770	EOL1	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	1.0250079533497471	[415]	[445]	8	hSpCas9	negative selection	11292241
67646882	67646905	11	+	28162770	EOL1	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-0.7484112101484506	[168]	[52]	-5	hSpCas9	negative selection	11292242
67646852	67646875	11	+	28162770	EOL1	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-0.07545222842946586	[5]	[2]	0	hSpCas9	negative selection	11292243
67646839	67646862	11	+	28162770	MOLM13	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.1754384877340502	[217]	[355]	8	hSpCas9	negative selection	11461600
67644808	67644831	11	+	28162770	MOLM13	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.8584709596580442	[162]	[64]	-5	hSpCas9	negative selection	11461601
67645749	67645772	11	+	28162770	MOLM13	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.7448967299309769	[273]	[331]	5	hSpCas9	negative selection	11461602
67645110	67645133	11	+	28162770	MOLM13	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.5989209080247346	[588]	[644]	4	hSpCas9	negative selection	11461603
67646994	67647017	11	+	28162770	MOLM13	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.5702510991742566	[203]	[218]	4	hSpCas9	negative selection	11461604
67645821	67645844	11	-	28162770	MOLM13	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.1757008491472856	[338]	[216]	-1	hSpCas9	negative selection	11461605
67645336	67645359	11	-	28162770	MOLM13	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.03880410778010224	[687]	[510]	0	hSpCas9	negative selection	11461606
67644825	67644848	11	-	28162770	MOLM13	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.13894085897944414	[308]	[245]	1	hSpCas9	negative selection	11461607
67646882	67646905	11	+	28162770	MOLM13	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.5049787002797989	[191]	[196]	4	hSpCas9	negative selection	11461608
67646852	67646875	11	+	28162770	MOLM13	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	2.7158168949881647	[3]	[18]	9	hSpCas9	negative selection	11461609
67646839	67646862	11	+	28162770	HEL	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	0.5122689001049483	[265]	[242]	4	hSpCas9	negative selection	11630966
67644808	67644831	11	+	28162770	HEL	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.9037846847406968	[120]	[144]	7	hSpCas9	negative selection	11630967
67645749	67645772	11	+	28162770	HEL	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	1.2865950217750817	[191]	[299]	9	hSpCas9	negative selection	11630968
67645110	67645133	11	+	28162770	HEL	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.13016523681694725	[514]	[360]	1	hSpCas9	negative selection	11630969
67646994	67647017	11	+	28162770	HEL	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.5782501055486433	[182]	[174]	5	hSpCas9	negative selection	11630970
67645821	67645844	11	-	28162770	HEL	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.5596989829604463	[358]	[155]	-4	hSpCas9	negative selection	11630971
67645336	67645359	11	-	28162770	HEL	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.22851206330811324	[592]	[444]	1	hSpCas9	negative selection	11630972
67644825	67644848	11	-	28162770	HEL	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.27192911419988086	[278]	[147]	-2	hSpCas9	negative selection	11630973
67646882	67646905	11	+	28162770	HEL	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-0.4765600963719873	[188]	[86]	-3	hSpCas9	negative selection	11630974
67646852	67646875	11	+	28162770	HEL	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-3.0577008861407355	[12]	[0]	-8	hSpCas9	negative selection	11630975
67646839	67646862	11	+	28162770	MV411	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	1.0978611947322654	[131]	[237]	8	hSpCas9	negative selection	11800332
67644808	67644831	11	+	28162770	MV411	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.8870353080807774	[94]	[147]	7	hSpCas9	negative selection	11800333
67645749	67645772	11	+	28162770	MV411	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.820142585748647	[196]	[292]	7	hSpCas9	negative selection	11800334
67645110	67645133	11	+	28162770	MV411	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	-0.1989641194054037	[371]	[272]	-1	hSpCas9	negative selection	11800335
67646994	67647017	11	+	28162770	MV411	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	-0.14540420238187235	[171]	[130]	-1	hSpCas9	negative selection	11800336
67645821	67645844	11	-	28162770	MV411	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.5818920615320905	[214]	[120]	-4	hSpCas9	negative selection	11800337
67645336	67645359	11	-	28162770	MV411	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	-0.46305583202223977	[629]	[384]	-3	hSpCas9	negative selection	11800338
67644825	67644848	11	-	28162770	MV411	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.4351357465648032	[320]	[199]	-3	hSpCas9	negative selection	11800339
67646882	67646905	11	+	28162770	MV411	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.15683500200186873	[114]	[107]	1	hSpCas9	negative selection	11800340
67646852	67646875	11	+	28162770	MV411	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-2.7525624492172245	[7]	[0]	-9	hSpCas9	negative selection	11800341
67646839	67646862	11	+	28162770	MONOMAC1	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.7486792745806834	[106]	[72]	-6	hSpCas9	negative selection	11969698
67644808	67644831	11	+	28162770	MONOMAC1	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	0.26636367378068915	[65]	[90]	2	hSpCas9	negative selection	11969699
67645749	67645772	11	+	28162770	MONOMAC1	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	-0.3993450223526692	[106]	[92]	-3	hSpCas9	negative selection	11969700
67645110	67645133	11	+	28162770	MONOMAC1	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	-0.23133002461343155	[297]	[290]	-2	hSpCas9	negative selection	11969701
67646994	67647017	11	+	28162770	MONOMAC1	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.6239930118951269	[89]	[158]	6	hSpCas9	negative selection	11969702
67645821	67645844	11	-	28162770	MONOMAC1	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.24547720211730684	[211]	[204]	-2	hSpCas9	negative selection	11969703
67645336	67645359	11	-	28162770	MONOMAC1	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.20495358205878667	[360]	[476]	2	hSpCas9	negative selection	11969704
67644825	67644848	11	-	28162770	MONOMAC1	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	-0.17996333370061235	[167]	[169]	-1	hSpCas9	negative selection	11969705
67646882	67646905	11	+	28162770	MONOMAC1	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	0.7444109705853335	[87]	[168]	7	hSpCas9	negative selection	11969706
67646852	67646875	11	+	28162770	MONOMAC1	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	4.446819342715171	[2]	[74]	9	hSpCas9	negative selection	11969707
67646839	67646862	11	+	28162770	OCIAML2	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.1065762546821224	[26]	[138]	-1	hSpCas9	negative selection	12139064
67644808	67644831	11	+	28162770	OCIAML2	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.16806705522172982	[14]	[73]	-1	hSpCas9	negative selection	12139065
67645749	67645772	11	+	28162770	OCIAML2	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.49284429873272484	[39]	[311]	5	hSpCas9	negative selection	12139066
67645110	67645133	11	+	28162770	OCIAML2	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.055580088194905786	[70]	[408]	0	hSpCas9	negative selection	12139067
67646994	67647017	11	+	28162770	OCIAML2	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	0.397865391629347	[32]	[240]	4	hSpCas9	negative selection	12139068
67645821	67645844	11	-	28162770	OCIAML2	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	0.08159588906699522	[51]	[304]	0	hSpCas9	negative selection	12139069
67645336	67645359	11	-	28162770	OCIAML2	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	-0.14605700909923502	[108]	[545]	-1	hSpCas9	negative selection	12139070
67644825	67644848	11	-	28162770	OCIAML2	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.42320461754091093	[36]	[274]	4	hSpCas9	negative selection	12139071
67646882	67646905	11	+	28162770	OCIAML2	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-0.20936451226142302	[33]	[162]	-2	hSpCas9	negative selection	12139072
67646852	67646875	11	+	28162770	OCIAML2	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-0.8856673245210054	[0]	[2]	-6	hSpCas9	negative selection	12139073
67646839	67646862	11	+	28162770	OCIAML3	viability	GGTCATGGTCCACGTAGCGGCGG	ACY3	ENSG00000132744	-0.8631942731395523	[46]	[77]	-6	hSpCas9	negative selection	12308430
67644808	67644831	11	+	28162770	OCIAML3	viability	GGGGAAGTCCACGACGCCCACGG	ACY3	ENSG00000132744	-0.07317547702272287	[22]	[65]	0	hSpCas9	negative selection	12308431
67645749	67645772	11	+	28162770	OCIAML3	viability	GCAGGTGCCCATGTTGGCCGTGG	ACY3	ENSG00000132744	0.4687281150237995	[44]	[187]	4	hSpCas9	negative selection	12308432
67645110	67645133	11	+	28162770	OCIAML3	viability	TCAGCCCGCAGCACACCCTGTGG	ACY3	ENSG00000132744	0.19448825448212492	[109]	[379]	1	hSpCas9	negative selection	12308433
67646994	67647017	11	+	28162770	OCIAML3	viability	GTCACAGCCACGCGACGCAGGGG	ACY3	ENSG00000132744	-0.2973906339659883	[45]	[112]	-2	hSpCas9	negative selection	12308434
67645821	67645844	11	-	28162770	OCIAML3	viability	GAGAGCTGAACCAGCTGCTGGGG	ACY3	ENSG00000132744	-0.026323131034842386	[55]	[165]	0	hSpCas9	negative selection	12308435
67645336	67645359	11	-	28162770	OCIAML3	viability	GCCAGGTCTTCCTGTACCAGCGG	ACY3	ENSG00000132744	0.6495042072448123	[154]	[733]	6	hSpCas9	negative selection	12308436
67644825	67644848	11	-	28162770	OCIAML3	viability	GATGGAAGCCTATAGACCCGTGG	ACY3	ENSG00000132744	0.5955461678670817	[72]	[332]	5	hSpCas9	negative selection	12308437
67646882	67646905	11	+	28162770	OCIAML3	viability	GTTGGCCAGCACAGGCACAGCGG	ACY3	ENSG00000132744	-1.0400720352236315	[46]	[68]	-6	hSpCas9	negative selection	12308438
67646852	67646875	11	+	28162770	OCIAML3	viability	GTAGCGGCGGCAGCCGGATGTGG	ACY3	ENSG00000132744	-1.5940076403241639	[2]	[2]	-8	hSpCas9	negative selection	12308439