Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 2015
  • Symbol: ADGRE1
  • Description: adhesion G protein-coupled receptor E1
DataSource: http://genomecrispr.dkfz.de/#!/results/ADGRE1

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
6905390 6905413 19 + 25494202 A375 resistance to PLX-4720 (puromycin) TCGCCCAGACTGGAGTGCAGGGG ADGRE1 ENSG00000174837 0.35999765204224765 [28,7] [7,0] 1 dCas9-VP64 positive selection 2386745
6921345 6921368 19 - 25494202 A375 resistance to PLX-4720 (puromycin) TCGCTGCAACCTCTGCCTCCGGG ADGRE1 ENSG00000174837 -0.9365880081613079 [154,441] [7,61] -5 dCas9-VP64 positive selection 2389218
6928894 6928917 19 + 25494202 A375 resistance to PLX-4720 (puromycin) GCGCCATTGCACTCCAGCCTAGG ADGRE1 ENSG00000174837 -0.7836007518198642 [44,14] [5,0] -4 dCas9-VP64 positive selection 2394697
6913291 6913314 19 + 25494202 A375 resistance to PLX-4720 (puromycin) GCCTCAGCCTCCCAAGTAGCTAG ADGRE1 ENSG00000174837 0.6911400425855385 [25,30] [5,13] 3 dCas9-VP64 positive selection 2396482
6919462 6919485 19 + 25494202 A375 resistance to PLX-4720 (puromycin) GTGTGTGTGTGTGTGTGTGTTGG ADGRE1 ENSG00000174837 4.847110262494055 [32,12] [264,23] 9 dCas9-VP64 positive selection 2428820
6921327 6921350 19 + 25494202 A375 resistance to PLX-4720 (puromycin) CAGAAGAATCGCTTGAACCCCGG ADGRE1 ENSG00000174837 0.6947743245442068 [118,16] [8,38] 3 dCas9-VP64 positive selection 2469063
6905390 6905413 19 + 25494202 A375 resistance to PLX-4720 (zeocin) TCGCCCAGACTGGAGTGCAGGGG ADGRE1 ENSG00000174837 0.05401708914906567 [74,30] [24,10] 0 dCas9-VP64 positive selection 2482000
6921345 6921368 19 - 25494202 A375 resistance to PLX-4720 (zeocin) TCGCTGCAACCTCTGCCTCCGGG ADGRE1 ENSG00000174837 -0.39148980799888866 [423,502] [155,76] -4 dCas9-VP64 positive selection 2484473
6928894 6928917 19 + 25494202 A375 resistance to PLX-4720 (zeocin) GCGCCATTGCACTCCAGCCTAGG ADGRE1 ENSG00000174837 -1.3426926137865989 [87,148] [18,10] -9 dCas9-VP64 positive selection 2489952
6913291 6913314 19 + 25494202 A375 resistance to PLX-4720 (zeocin) GCCTCAGCCTCCCAAGTAGCTAG ADGRE1 ENSG00000174837 0.4030393266100577 [90,274] [19,131] 3 dCas9-VP64 positive selection 2491737
6919462 6919485 19 + 25494202 A375 resistance to PLX-4720 (zeocin) GTGTGTGTGTGTGTGTGTGTTGG ADGRE1 ENSG00000174837 0.8889753160498469 [90,141] [86,53] 6 dCas9-VP64 positive selection 2524075
6921327 6921350 19 + 25494202 A375 resistance to PLX-4720 (zeocin) CAGAAGAATCGCTTGAACCCCGG ADGRE1 ENSG00000174837 -1.217410828372933 [137,230] [25,24] -9 dCas9-VP64 positive selection 2564318
6919685 6919708 19 + 26780180 HT29 viability (Avana library 4 designs) ATGACTGGAGAGAAGAAAGACGG ADGRE1 ENSG00000174837 2.64455826974562 [] [] 8 hSpCas9 negative selection 3405089
6913788 6913811 19 - 26780180 HT29 viability (Avana library 4 designs) GCCGGAGTGATATTTGCTGAGGG ADGRE1 ENSG00000174837 0.868538359489914 [] [] 3 hSpCas9 negative selection 3405090
6897253 6897276 19 - 26780180 HT29 viability (Avana library 4 designs) GGGACCCAGTCATTTCCAGTGGG ADGRE1 ENSG00000174837 0.485761776517771 [] [] 1 hSpCas9 negative selection 3405091
6906502 6906525 19 - 26780180 HT29 viability (Avana library 4 designs) TGCATATGCAGGTTTCACTGCGG ADGRE1 ENSG00000174837 -0.303969052657278 [] [] -5 hSpCas9 negative selection 3405092
6906502 6906525 19 - 26780180 A375 viability (Avana lentiCRISPRv2) TGCATATGCAGGTTTCACTGCGG ADGRE1 ENSG00000174837 2.3422721261675 [] [] 3 hSpCas9 negative selection 3476935
6897253 6897276 19 - 26780180 A375 viability (Avana lentiCRISPRv2) GGGACCCAGTCATTTCCAGTGGG ADGRE1 ENSG00000174837 3.11309454663115 [] [] 5 hSpCas9 negative selection 3476936
6913788 6913811 19 - 26780180 A375 viability (Avana lentiCRISPRv2) GCCGGAGTGATATTTGCTGAGGG ADGRE1 ENSG00000174837 4.23254732625379 [] [] 7 hSpCas9 negative selection 3476937
6919685 6919708 19 + 26780180 A375 viability (Avana lentiCRISPRv2) ATGACTGGAGAGAAGAAAGACGG ADGRE1 ENSG00000174837 -7.91211522198861 [] [] -7 hSpCas9 negative selection 3476938
6906476 6906499 19 + 26780180 A375 viability (Avana lentiCRISPRv2) GCAGATCCAGCAATGCCAAGAGG ADGRE1 ENSG00000174837 1.67076221879739 [] [] 2 hSpCas9 negative selection 3476939
6890522 6890545 19 + 26780180 A375 viability (Avana lentiCRISPRv2) ACACGGAAACCAAACACAAAGGG ADGRE1 ENSG00000174837 -1.57102938470643 [] [] -2 hSpCas9 negative selection 3476940
6906502 6906525 19 - 26780180 A375 viability (Avana lentiGuide) TGCATATGCAGGTTTCACTGCGG ADGRE1 ENSG00000174837 -3.18305814583085 [] [] -5 hSpCas9 negative selection 3585594
6897253 6897276 19 - 26780180 A375 viability (Avana lentiGuide) GGGACCCAGTCATTTCCAGTGGG ADGRE1 ENSG00000174837 1.35810213971034 [] [] 1 hSpCas9 negative selection 3585595
6913788 6913811 19 - 26780180 A375 viability (Avana lentiGuide) GCCGGAGTGATATTTGCTGAGGG ADGRE1 ENSG00000174837 -5.95506957502238 [] [] -8 hSpCas9 negative selection 3585596
6919685 6919708 19 + 26780180 A375 viability (Avana lentiGuide) ATGACTGGAGAGAAGAAAGACGG ADGRE1 ENSG00000174837 9.75979707972604 [] [] 6 hSpCas9 negative selection 3585597
6906476 6906499 19 + 26780180 A375 viability (Avana lentiGuide) GCAGATCCAGCAATGCCAAGAGG ADGRE1 ENSG00000174837 -5.28971485012176 [] [] -8 hSpCas9 negative selection 3585598
6890522 6890545 19 + 26780180 A375 viability (Avana lentiGuide) ACACGGAAACCAAACACAAAGGG ADGRE1 ENSG00000174837 2.37692596648104 [] [] 2 hSpCas9 negative selection 3585599
6906502 6906525 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TGCATATGCAGGTTTCACTGCGG ADGRE1 ENSG00000174837 0.09784490470583433 [5] [5,5] 2 hSpCas9 positive selection 3694253
6897253 6897276 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GGGACCCAGTCATTTCCAGTGGG ADGRE1 ENSG00000174837 -0.36317753501894934 [4] [4,1] -5 hSpCas9 positive selection 3694254
6913788 6913811 19 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCCGGAGTGATATTTGCTGAGGG ADGRE1 ENSG00000174837 0.2937420967108386 [4] [5,5] 8 hSpCas9 positive selection 3694255
6919685 6919708 19 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ATGACTGGAGAGAAGAAAGACGG ADGRE1 ENSG00000174837 -0.8241167164508287 [5] [4,1] -8 hSpCas9 positive selection 3694256
6906476 6906499 19 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCAGATCCAGCAATGCCAAGAGG ADGRE1 ENSG00000174837 0.18356213021728884 [5] [6,5] 5 hSpCas9 positive selection 3694257
6890522 6890545 19 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ACACGGAAACCAAACACAAAGGG ADGRE1 ENSG00000174837 -0.45895600098737743 [4] [2,3] -6 hSpCas9 positive selection 3694258
6906502 6906525 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TGCATATGCAGGTTTCACTGCGG ADGRE1 ENSG00000174837 0.21084005525139718 [5] [5,5] 5 hSpCas9 positive selection 3802860
6897253 6897276 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GGGACCCAGTCATTTCCAGTGGG ADGRE1 ENSG00000174837 -0.4479490346323002 [5] [2,4] -5 hSpCas9 positive selection 3802861
6913788 6913811 19 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCCGGAGTGATATTTGCTGAGGG ADGRE1 ENSG00000174837 0.1049004850034582 [5] [4,5] 2 hSpCas9 positive selection 3802862
6919685 6919708 19 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ATGACTGGAGAGAAGAAAGACGG ADGRE1 ENSG00000174837 -0.16893414486160307 [5] [4,2] -2 hSpCas9 positive selection 3802863
6906476 6906499 19 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCAGATCCAGCAATGCCAAGAGG ADGRE1 ENSG00000174837 0.2234341023174698 [5] [6,3] 6 hSpCas9 positive selection 3802864
6890522 6890545 19 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ACACGGAAACCAAACACAAAGGG ADGRE1 ENSG00000174837 -0.24788584699352845 [4] [3,2] -3 hSpCas9 positive selection 3802865
6887629 6887652 19 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CCTCACACTCACCCCAGAAGAGG ADGRE1 ENSG00000174837 0.006089123314565681 [4] [2,3] 0 hSpCas9 positive selection 4134666
6890481 6890504 19 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.2208645460964293 [5] [4,4] 5 hSpCas9 positive selection 4134667
6887616 6887639 19 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.2989909700442588 [7] [5,6] 7 hSpCas9 positive selection 4134668
6887629 6887652 19 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CCTCACACTCACCCCAGAAGAGG ADGRE1 ENSG00000174837 0.7269762263800609 [5] [5,4,2,3] 5 hSpCas9 positive selection 4198688
6890481 6890504 19 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.6921532876273992 [5] [5,4,2,3] 4 hSpCas9 positive selection 4198689
6887616 6887639 19 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 1.123089661161473 [6] [6,6,4,7] 8 hSpCas9 positive selection 4198690
6890531 6890554 19 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.4836984471680467 [3] [4,3] 8 hSpCas9 positive selection 4268773
6890481 6890504 19 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.22539191195765082 [2] [2,0] -4 hSpCas9 positive selection 4268774
6887616 6887639 19 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.4240748865549106 [3] [4,3] 8 hSpCas9 positive selection 4333038
6887623 6887646 19 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.13242135383935927 [0] [0,0] -3 hSpCas9 positive selection 4333039
6890531 6890554 19 - 27260156 BXPC3 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.4827459272612479 [792] [960,1117,1417,1157] 8 hSpCas9 negative selection 5541233
6890481 6890504 19 + 27260156 BXPC3 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.5294231720012195 [285] [362,479,390,501] 9 hSpCas9 negative selection 5541234
6887616 6887639 19 + 27260156 BXPC3 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.3119753330420326 [891] [1078,1019,1097,1481] 6 hSpCas9 negative selection 5605498
6887623 6887646 19 - 27260156 BXPC3 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.012946047262980542 [29] [58,18,15,26] 0 hSpCas9 negative selection 5605499
6890531 6890554 19 - 27260156 A673 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.3815184305922098 [792] [1448,1148,1227,1154] 8 hSpCas9 negative selection 5662484
6890481 6890504 19 + 27260156 A673 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.28893292316460567 [285] [343,415,431,479] 6 hSpCas9 negative selection 5662485
6887616 6887639 19 + 27260156 A673 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.3159366610133415 [891] [1472,1210,1342,1321] 7 hSpCas9 negative selection 5726749
6887623 6887646 19 - 27260156 A673 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.06398010459111658 [29] [21,28,40,44] -1 hSpCas9 negative selection 5726750
6890531 6890554 19 - 27260156 A375 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.6027541847784398 [792] [1357,1632,1587,1108] 8 hSpCas9 negative selection 5783735
6890481 6890504 19 + 27260156 A375 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.13766578654248707 [285] [177,321,400,538] 2 hSpCas9 negative selection 5783736
6887616 6887639 19 + 27260156 A375 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.7827150812996165 [891] [2122,2175,1540,1422] 9 hSpCas9 negative selection 5848000
6887623 6887646 19 - 27260156 A375 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.055153895952051 [29] [79,45,1,20] 0 hSpCas9 negative selection 5848001
6890531 6890554 19 - 27260156 COLO741 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.3152158180291652 [792] [1243,1234,1295] 6 hSpCas9 negative selection 5904986
6890481 6890504 19 + 27260156 COLO741 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.11780746143848408 [285] [504,216,303] -3 hSpCas9 negative selection 5904987
6887616 6887639 19 + 27260156 COLO741 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.370817974874902 [891] [1564,1588,1285] 7 hSpCas9 negative selection 5969251
6887623 6887646 19 - 27260156 COLO741 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.36271647114668815 [29] [58,19,13] -7 hSpCas9 negative selection 5969252
6890531 6890554 19 - 27260156 CAL120 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.6541427949850503 [792] [1723,1528,1432] 8 hSpCas9 negative selection 6026237
6890481 6890504 19 + 27260156 CAL120 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.2860233683999793 [285] [436,202,257] -4 hSpCas9 negative selection 6026238
6887616 6887639 19 + 27260156 CAL120 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.5314083585911932 [891] [1761,1580,1494] 7 hSpCas9 negative selection 6090502
6887623 6887646 19 - 27260156 CAL120 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.1691881655513212 [29] [0,34,82] 2 hSpCas9 negative selection 6090503
6890531 6890554 19 - 27260156 CADOES1 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.7851053897070625 [792] [1302,1282,1218,1278] 9 hSpCas9 negative selection 6147488
6890481 6890504 19 + 27260156 CADOES1 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.5693803509690594 [285] [438,376,461,296] 8 hSpCas9 negative selection 6147489
6887616 6887639 19 + 27260156 CADOES1 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.6390648225113463 [891] [1417,993,1434,1320] 9 hSpCas9 negative selection 6211753
6887623 6887646 19 - 27260156 CADOES1 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.1174299366454679 [29] [20,23,4,0] -9 hSpCas9 negative selection 6211754
6890531 6890554 19 - 27260156 EWS502 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.481865830604432 [792] [1140,888,1062,1641] 8 hSpCas9 negative selection 6268739
6890481 6890504 19 + 27260156 EWS502 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.32531749613290467 [285] [318,300,422,492] 6 hSpCas9 negative selection 6268740
6887616 6887639 19 + 27260156 EWS502 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.579986464890979 [891] [1074,1388,1560,1681] 8 hSpCas9 negative selection 6333004
6887623 6887646 19 - 27260156 EWS502 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.22238053013042736 [29] [54,17,13,17] -4 hSpCas9 negative selection 6333005
6890531 6890554 19 - 27260156 EW8 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.5813700518766843 [792] [1135,873,844,1026] 8 hSpCas9 negative selection 6389990
6890481 6890504 19 + 27260156 EW8 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.0970170341552089 [285] [216,220,284,257] 1 hSpCas9 negative selection 6389991
6887616 6887639 19 + 27260156 EW8 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.33689649693295987 [891] [1163,957,769,809] 6 hSpCas9 negative selection 6454255
6887623 6887646 19 - 27260156 EW8 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.08204786739601966 [29] [17,53,14,16] 1 hSpCas9 negative selection 6454256
6890531 6890554 19 - 27260156 CORL105 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.6073172843501716 [792] [1448,1366,1603,1268] 9 hSpCas9 negative selection 6511241
6890481 6890504 19 + 27260156 CORL105 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.22386238458960334 [285] [437,362,339,416] 4 hSpCas9 negative selection 6511242
6887616 6887639 19 + 27260156 CORL105 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.19891700700678083 [891] [1130,1051,1443,1205] 4 hSpCas9 negative selection 6575506
6887623 6887646 19 - 27260156 CORL105 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.6933409050809156 [29] [18,42,18,4] -8 hSpCas9 negative selection 6575507
6890531 6890554 19 - 27260156 HS294T viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.5091767831425157 [792] [356,375,563,460] 6 hSpCas9 negative selection 6632492
6890481 6890504 19 + 27260156 HS294T viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.2709167897812894 [285] [153,123,147,99] 3 hSpCas9 negative selection 6632493
6887616 6887639 19 + 27260156 HS294T viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.3889437331420246 [891] [399,326,606,485] 5 hSpCas9 negative selection 6696757
6887623 6887646 19 - 27260156 HS294T viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -2.0979103387251326 [29] [0,3,2,2] -9 hSpCas9 negative selection 6696758
6890531 6890554 19 - 27260156 HCC44 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.4961166604585078 [792] [1362,1405,1381,918] 7 hSpCas9 negative selection 6753743
6890481 6890504 19 + 27260156 HCC44 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.13540580292042537 [285] [220,205,549,249] -2 hSpCas9 negative selection 6753744
6887616 6887639 19 + 27260156 HCC44 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.605383714968292 [891] [1492,1310,1706,1668] 8 hSpCas9 negative selection 6818008
6887623 6887646 19 - 27260156 HCC44 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.38680956920674925 [29] [51,37,75,18] 6 hSpCas9 negative selection 6818009
6890531 6890554 19 - 27260156 G402 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.7008119497714361 [792] [1467,1289,1382,2086] 8 hSpCas9 negative selection 6874994
6890481 6890504 19 + 27260156 G402 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.22753819477234366 [285] [498,239,550,348] 3 hSpCas9 negative selection 6874995
6887616 6887639 19 + 27260156 G402 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.8165293591145272 [891] [2585,1986,1783,1427] 8 hSpCas9 negative selection 6939259
6887623 6887646 19 - 27260156 G402 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.8848963634054399 [29] [60,0,21,0] -8 hSpCas9 negative selection 6939260
6890531 6890554 19 - 27260156 L33 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.5478265290476577 [792] [1054,443,697,1387] 9 hSpCas9 negative selection 6996245
6890481 6890504 19 + 27260156 L33 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.3418478378348385 [285] [335,118,291,359] 7 hSpCas9 negative selection 6996246
6887616 6887639 19 + 27260156 L33 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.25767721499618645 [891] [997,453,655,1116] 5 hSpCas9 negative selection 7060510
6887623 6887646 19 - 27260156 L33 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.0908822742876123 [29] [4,10,7,11] -9 hSpCas9 negative selection 7060511
6890531 6890554 19 - 27260156 K562 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.40400025873455825 [792] [1010,802,1055,858] 5 hSpCas9 negative selection 7117496
6890481 6890504 19 + 27260156 K562 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.151718129967357 [285] [261,143,290,405] 1 hSpCas9 negative selection 7117497
6887616 6887639 19 + 27260156 K562 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.9478451018156636 [891] [1935,1426,1375,1404] 9 hSpCas9 negative selection 7181761
6887623 6887646 19 - 27260156 K562 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -2.73228250003755 [29] [0,3,8,1] -9 hSpCas9 negative selection 7181762
6890531 6890554 19 - 27260156 HT29 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.5820668014163085 [792] [1450,1444,1382,1478] 9 hSpCas9 negative selection 7238747
6890481 6890504 19 + 27260156 HT29 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.23586688532130107 [285] [376,352,448,443] 4 hSpCas9 negative selection 7238748
6887616 6887639 19 + 27260156 HT29 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.5311438901899356 [891] [1681,1621,1516,1461] 8 hSpCas9 negative selection 7303012
6887623 6887646 19 - 27260156 HT29 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.3991785326244908 [29] [25,7,19,2] -9 hSpCas9 negative selection 7303013
6890531 6890554 19 - 27260156 MHHES1 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.6337761447258693 [792] [1872,1204,1351,1171] 9 hSpCas9 negative selection 7359998
6890481 6890504 19 + 27260156 MHHES1 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.011007857971476187 [285] [408,274,201,376] 0 hSpCas9 negative selection 7359999
6887616 6887639 19 + 27260156 MHHES1 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.20844627026101692 [891] [1144,1310,1282,942] 4 hSpCas9 negative selection 7424263
6887623 6887646 19 - 27260156 MHHES1 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.716847785280248 [29] [35,0,0,5] -9 hSpCas9 negative selection 7424264
6890531 6890554 19 - 27260156 MEWO viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.2828183667137373 [792] [1018,712,998] 6 hSpCas9 negative selection 7481249
6890481 6890504 19 + 27260156 MEWO viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.1487338176805335 [285] [236,350,289] 3 hSpCas9 negative selection 7481250
6887616 6887639 19 + 27260156 MEWO viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.562705340791909 [891] [1340,1145,1231] 9 hSpCas9 negative selection 7545514
6887623 6887646 19 - 27260156 MEWO viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.7088493086392873 [29] [31,30,71] 9 hSpCas9 negative selection 7545515
6890531 6890554 19 - 27260156 LNCAPCLONEFGC viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.542034626264886 [792] [958,882,1271,1114] 8 hSpCas9 negative selection 7602500
6890481 6890504 19 + 27260156 LNCAPCLONEFGC viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.4427881094749506 [285] [392,273,461,299] 7 hSpCas9 negative selection 7602501
6887616 6887639 19 + 27260156 LNCAPCLONEFGC viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.8062710804712049 [891] [1430,1495,1600,1144] 9 hSpCas9 negative selection 7666765
6887623 6887646 19 - 27260156 LNCAPCLONEFGC viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.1909050729083055 [29] [48,6,28,39] 3 hSpCas9 negative selection 7666766
6890531 6890554 19 - 27260156 PANC0327 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.7284689418473252 [792] [1291,1185,1101,1095] 9 hSpCas9 negative selection 7723751
6890481 6890504 19 + 27260156 PANC0327 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.543061620866585 [285] [298,281,358,545] 7 hSpCas9 negative selection 7723752
6887616 6887639 19 + 27260156 PANC0327 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.2856899689939755 [891] [915,830,1186,942] 4 hSpCas9 negative selection 7788016
6887623 6887646 19 - 27260156 PANC0327 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.5894460553114249 [29] [9,3,33,23] -7 hSpCas9 negative selection 7788017
6890531 6890554 19 - 27260156 NCIH2009 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.7728431033457764 [792] [2177,2020,1530] 9 hSpCas9 negative selection 7845002
6890481 6890504 19 + 27260156 NCIH2009 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.5917910997933742 [285] [707,687,428] 7 hSpCas9 negative selection 7845003
6887616 6887639 19 + 27260156 NCIH2009 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.5905367511215508 [891] [2110,1492,2075] 7 hSpCas9 negative selection 7909267
6887623 6887646 19 - 27260156 NCIH2009 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.8772233590775689 [29] [29,4,2] -9 hSpCas9 negative selection 7909268
6890531 6890554 19 - 27260156 NCIH1373 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 1.2152120817935006 [792] [1498,2491,1949,571] 9 hSpCas9 negative selection 7966253
6890481 6890504 19 + 27260156 NCIH1373 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.23354952093028825 [285] [456,518,206,83] 2 hSpCas9 negative selection 7966254
6887616 6887639 19 + 27260156 NCIH1373 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.42230546674114533 [891] [1597,1280,1319,312] 4 hSpCas9 negative selection 8030518
6887623 6887646 19 - 27260156 NCIH1373 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -2.86596719452158 [29] [2,1,5,1] -9 hSpCas9 negative selection 8030519
6890531 6890554 19 - 27260156 PATU8902 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.8406135206716158 [792] [1797,2389,1373,2563] 8 hSpCas9 negative selection 8087504
6890481 6890504 19 + 27260156 PATU8902 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.38057637590319326 [285] [562,438,379,750] 4 hSpCas9 negative selection 8087505
6887616 6887639 19 + 27260156 PATU8902 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.9349271834916214 [891] [2628,1835,1920,3320] 8 hSpCas9 negative selection 8151769
6887623 6887646 19 - 27260156 PATU8902 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.4324120891034 [29] [1,57,1,1] -8 hSpCas9 negative selection 8151770
6890531 6890554 19 - 27260156 PANC1 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.7904858071413171 [792] [1025,1402,1367,979] 9 hSpCas9 negative selection 8208755
6890481 6890504 19 + 27260156 PANC1 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.5468136238930844 [285] [402,457,381,227] 8 hSpCas9 negative selection 8208756
6887616 6887639 19 + 27260156 PANC1 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.4117566417074846 [891] [1135,907,1024,972] 6 hSpCas9 negative selection 8273020
6887623 6887646 19 - 27260156 PANC1 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.3246111273186516 [29] [35,4,62,20] 5 hSpCas9 negative selection 8273021
6890531 6890554 19 - 27260156 PANC0813 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.7306890854437084 [792] [1548,1538,1671,1427] 9 hSpCas9 negative selection 8330006
6890481 6890504 19 + 27260156 PANC0813 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.42824848464964993 [285] [511,588,430,289] 7 hSpCas9 negative selection 8330007
6887616 6887639 19 + 27260156 PANC0813 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.3477258227563268 [891] [1484,1288,1223,1345] 5 hSpCas9 negative selection 8394271
6887623 6887646 19 - 27260156 PANC0813 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.6046177953241236 [29] [13,66,29,96] 8 hSpCas9 negative selection 8394272
6890531 6890554 19 - 27260156 RDES viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.6318793063806015 [792] [1205,1239,1439,1852] 8 hSpCas9 negative selection 8451257
6890481 6890504 19 + 27260156 RDES viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.33881219725711725 [285] [324,438,377,544] 5 hSpCas9 negative selection 8451258
6887616 6887639 19 + 27260156 RDES viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.49078576884184744 [891] [1167,1514,1628,1472] 7 hSpCas9 negative selection 8515522
6887623 6887646 19 - 27260156 RDES viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.3053293795816834 [29] [21,27,36,24] -5 hSpCas9 negative selection 8515523
6890531 6890554 19 - 27260156 PC3 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.3382179972978653 [792] [587,959,1493,1248] 7 hSpCas9 negative selection 8572508
6890481 6890504 19 + 27260156 PC3 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.13263194880845652 [285] [207,190,323,340] -3 hSpCas9 negative selection 8572509
6887616 6887639 19 + 27260156 PC3 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.16808399076266223 [891] [582,930,1701,1155] 4 hSpCas9 negative selection 8636773
6887623 6887646 19 - 27260156 PC3 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.2161468239692321 [29] [3,19,19,12] -9 hSpCas9 negative selection 8636774
6890531 6890554 19 - 27260156 PATU8988T viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.3215614688755116 [792] [990,924,1082,814] 5 hSpCas9 negative selection 8693759
6890481 6890504 19 + 27260156 PATU8988T viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.3123129824001483 [285] [287,346,317,426] 5 hSpCas9 negative selection 8693760
6887616 6887639 19 + 27260156 PATU8988T viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.5403391725186623 [891] [1374,1334,1394,884] 8 hSpCas9 negative selection 8758024
6887623 6887646 19 - 27260156 PATU8988T viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.08465324335817481 [29] [73,35,3,7] 1 hSpCas9 negative selection 8758025
6890531 6890554 19 - 27260156 T47D viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.5921875690112236 [792] [1376,1466,1425,1289] 9 hSpCas9 negative selection 8815010
6890481 6890504 19 + 27260156 T47D viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.23743313672932564 [285] [401,275,435,468] 5 hSpCas9 negative selection 8815011
6887616 6887639 19 + 27260156 T47D viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.39556314758202327 [891] [1340,1289,1379,1465] 8 hSpCas9 negative selection 8879275
6887623 6887646 19 - 27260156 T47D viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.46579646543696285 [29] [48,31,48,64] 8 hSpCas9 negative selection 8879276
6890531 6890554 19 - 27260156 SU8686 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.6934893109224279 [792] [1252,1135,1257,1482] 9 hSpCas9 negative selection 8936261
6890481 6890504 19 + 27260156 SU8686 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.4096937452775939 [285] [338,289,370,546] 7 hSpCas9 negative selection 8936262
6887616 6887639 19 + 27260156 SU8686 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.3628619424676024 [891] [969,873,1188,1644] 6 hSpCas9 negative selection 9000526
6887623 6887646 19 - 27260156 SU8686 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -2.2942731335826365 [29] [13,0,1,6] -9 hSpCas9 negative selection 9000527
6890531 6890554 19 - 27260156 SKES1 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.45847558739305294 [792] [1224,1046,1035,1047] 8 hSpCas9 negative selection 9057512
6890481 6890504 19 + 27260156 SKES1 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.1805835230357452 [285] [299,249,268,197] -4 hSpCas9 negative selection 9057513
6887616 6887639 19 + 27260156 SKES1 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.4438709155538566 [891] [1438,1399,1035,1031] 8 hSpCas9 negative selection 9121777
6887623 6887646 19 - 27260156 SKES1 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -0.20825983426295958 [29] [32,48,25,1] -4 hSpCas9 negative selection 9121778
6890531 6890554 19 - 27260156 TOV112D viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.8830429715329812 [792] [1401,1508,1622,1331] 9 hSpCas9 negative selection 9178763
6890481 6890504 19 + 27260156 TOV112D viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.17183220878819327 [285] [319,210,168,309] -3 hSpCas9 negative selection 9178764
6887616 6887639 19 + 27260156 TOV112D viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.3390057152100422 [891] [1336,1032,1055,1086] 6 hSpCas9 negative selection 9243028
6887623 6887646 19 - 27260156 TOV112D viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 -1.1259690488708345 [29] [0,33,11,11] -9 hSpCas9 negative selection 9243029
6890531 6890554 19 - 27260156 TC71 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.4520399336201052 [792] [1123,1127,1172,1230] 9 hSpCas9 negative selection 9300014
6890481 6890504 19 + 27260156 TC71 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 -0.059536498990213405 [285] [265,367,277,263] -1 hSpCas9 negative selection 9300015
6887616 6887639 19 + 27260156 TC71 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.25758592303394245 [891] [1107,1049,1077,1351] 6 hSpCas9 negative selection 9364279
6887623 6887646 19 - 27260156 TC71 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.7418888427968575 [29] [42,92,28,50] 9 hSpCas9 negative selection 9364280
6890531 6890554 19 - 27260156 TC32 viability GCCAACTTACCCTTTGTGTTTGG ADGRE1 ENSG00000174837 0.5035601256469738 [792] [1031,741,1453,1130] 8 hSpCas9 negative selection 9421265
6890481 6890504 19 + 27260156 TC32 viability GATGTTGTGTTATGCACAGCTGG ADGRE1 ENSG00000174837 0.24555487063804393 [285] [299,132,411,512] 4 hSpCas9 negative selection 9421266
6887616 6887639 19 + 27260156 TC32 viability GCTTCAACCTGCTCCTCTTCTGG ADGRE1 ENSG00000174837 0.35703279105731334 [891] [1000,736,1541,1175] 6 hSpCas9 negative selection 9485530
6887623 6887646 19 - 27260156 TC32 viability ACTCACCCCAGAAGAGGAGCAGG ADGRE1 ENSG00000174837 0.5435822793551943 [29] [58,0,86,35] 8 hSpCas9 negative selection 9485531