Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 84335
• Symbol: AKT1S1
• Description: AKT1 substrate 1

DataSource: http://genomecrispr.dkfz.de/#!/results/AKT1S1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
49873253	49873276	19	-	26472758	Jiyoye	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-1.7597219272388709	[237]	[52]	-8	hSpCas9	negative selection	5056
49872994	49873017	19	+	26472758	Jiyoye	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.006637451922144599	[98]	[74]	0	hSpCas9	negative selection	5057
49873127	49873150	19	-	26472758	Jiyoye	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.4817933061053825	[99]	[26]	-7	hSpCas9	negative selection	5058
49873070	49873093	19	+	26472758	Jiyoye	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-0.3583593648571033	[16]	[9]	-3	hSpCas9	negative selection	5059
49873024	49873047	19	+	26472758	Jiyoye	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-0.9054148488021528	[76]	[30]	-6	hSpCas9	negative selection	5060
49872980	49873003	19	-	26472758	Jiyoye	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.1832793695790379	[159]	[136]	1	hSpCas9	negative selection	5061
49872930	49872953	19	+	26472758	Jiyoye	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.6741247205959747	[291]	[137]	-5	hSpCas9	negative selection	5062
49871604	49871627	19	+	26472758	Jiyoye	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.5544013346890513	[120]	[133]	4	hSpCas9	negative selection	5063
49873196	49873219	19	-	26472758	Jiyoye	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.5928246184941266	[59]	[14]	-8	hSpCas9	negative selection	5064
49873091	49873114	19	+	26472758	Jiyoye	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	0.4467037456925109	[107]	[110]	3	hSpCas9	negative selection	5065
49873253	49873276	19	-	26472758	KBM7	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-1.954563863255971	[866,795]	[177,31]	-8	hSpCas9	negative selection	196174
49872994	49873017	19	+	26472758	KBM7	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.3535380886791226	[164,161]	[105,91]	4	hSpCas9	negative selection	196175
49873127	49873150	19	-	26472758	KBM7	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-0.6687903595338234	[329,231]	[71,90]	-5	hSpCas9	negative selection	196176
49873070	49873093	19	+	26472758	KBM7	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	0.7128570300593511	[129,95]	[82,88]	7	hSpCas9	negative selection	196177
49873024	49873047	19	+	26472758	KBM7	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	0.2626422494976799	[146,169]	[80,98]	2	hSpCas9	negative selection	196178
49872980	49873003	19	-	26472758	KBM7	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.06306312852892078	[637,341]	[301,173]	0	hSpCas9	negative selection	196179
49872930	49872953	19	+	26472758	KBM7	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.5332355238220762	[804,544]	[499,409]	6	hSpCas9	negative selection	196180
49871604	49871627	19	+	26472758	KBM7	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.8312737047035638	[437,274]	[382,211]	8	hSpCas9	negative selection	196181
49873196	49873219	19	-	26472758	KBM7	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-0.30476495137616	[286,303]	[115,110]	-3	hSpCas9	negative selection	196182
49873091	49873114	19	+	26472758	KBM7	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	0.8735772574501321	[616,554]	[682,344]	8	hSpCas9	negative selection	196183
49873253	49873276	19	-	26472758	Raji	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.575611048308083	[410]	[7]	-9	hSpCas9	negative selection	387292
49872994	49873017	19	+	26472758	Raji	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.11869884860143354	[126]	[31]	1	hSpCas9	negative selection	387293
49873127	49873150	19	-	26472758	Raji	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-0.9282403743571219	[163]	[19]	-6	hSpCas9	negative selection	387294
49873070	49873093	19	+	26472758	Raji	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-0.5930561827674925	[38]	[5]	-5	hSpCas9	negative selection	387295
49873024	49873047	19	+	26472758	Raji	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-1.7339187186073424	[85]	[5]	-8	hSpCas9	negative selection	387296
49872980	49873003	19	-	26472758	Raji	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.47935231276055745	[135]	[43]	4	hSpCas9	negative selection	387297
49872930	49872953	19	+	26472758	Raji	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.23095822049213233	[491]	[133]	2	hSpCas9	negative selection	387298
49871604	49871627	19	+	26472758	Raji	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.5303262327377897	[181]	[60]	5	hSpCas9	negative selection	387299
49873196	49873219	19	-	26472758	Raji	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.828801367028957	[198]	[12]	-8	hSpCas9	negative selection	387300
49873091	49873114	19	+	26472758	Raji	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.3951168051555837	[356]	[62]	-3	hSpCas9	negative selection	387301
49873253	49873276	19	-	26472758	K562	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-6.329769301460534	[666]	[6]	-9	hSpCas9	negative selection	578410
49872994	49873017	19	+	26472758	K562	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.024070108259454992	[105]	[87]	0	hSpCas9	negative selection	578411
49873127	49873150	19	-	26472758	K562	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.282017696448254	[313]	[108]	-6	hSpCas9	negative selection	578412
49873070	49873093	19	+	26472758	K562	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-2.8430441135838924	[84]	[9]	-8	hSpCas9	negative selection	578413
49873024	49873047	19	+	26472758	K562	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-2.157679715904899	[147]	[27]	-7	hSpCas9	negative selection	578414
49872980	49873003	19	-	26472758	K562	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.0436009581514709	[430]	[352]	0	hSpCas9	negative selection	578415
49872930	49872953	19	+	26472758	K562	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.31637746192395705	[443]	[300]	-2	hSpCas9	negative selection	578416
49871604	49871627	19	+	26472758	K562	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.27653091282019965	[310]	[317]	2	hSpCas9	negative selection	578417
49873196	49873219	19	-	26472758	K562	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-2.364390515009077	[182]	[29]	-8	hSpCas9	negative selection	578418
49873091	49873114	19	+	26472758	K562	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.5949746794239573	[534]	[298]	-4	hSpCas9	negative selection	578419
49869948	49869971	19	+	26627737	DLD1	viability	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.44502769950711957	[568]	[288,249,194]	4	hSpCas9	negative selection	806236
49870038	49870061	19	+	26627737	DLD1	viability	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.6172738887342701	[1324]	[243,260,299]	-6	hSpCas9	negative selection	806237
49872984	49873007	19	+	26627737	DLD1	viability	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.10483993729273289	[1668]	[349,662,454]	-1	hSpCas9	negative selection	806238
49873133	49873156	19	-	26627737	DLD1	viability	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.23948135530045886	[459]	[266,35,66]	-3	hSpCas9	negative selection	806239
49876599	49876622	19	+	26627737	DLD1	viability	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	-0.31358198796957826	[1611]	[557,255,396]	-3	hSpCas9	negative selection	806240
49876627	49876650	19	-	26627737	DLD1	viability	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.922242415131191	[638]	[141,69,102]	-7	hSpCas9	negative selection	806241
49869948	49869971	19	+	26627737	GBM cells	viability after 5 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.3288920426371268	[355]	[182,120]	-5	hSpCas9	negative selection	888551
49870038	49870061	19	+	26627737	GBM cells	viability after 5 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.3773221293088078	[504]	[228,187]	-5	hSpCas9	negative selection	888552
49872984	49873007	19	+	26627737	GBM cells	viability after 5 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.34510007273519383	[377]	[285,228]	5	hSpCas9	negative selection	888553
49873133	49873156	19	-	26627737	GBM cells	viability after 5 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.09611987222096491	[289]	[161,128]	-1	hSpCas9	negative selection	888554
49876599	49876622	19	+	26627737	GBM cells	viability after 5 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.07833300223980988	[588]	[289,376]	1	hSpCas9	negative selection	888555
49876627	49876650	19	-	26627737	GBM cells	viability after 5 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.32089743977739243	[258]	[144,201]	5	hSpCas9	negative selection	888556
49869948	49869971	19	+	26627737	GBM cells	viability after 13 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.5279369940670605	[355]	[128,137]	-6	hSpCas9	negative selection	970866
49870038	49870061	19	+	26627737	GBM cells	viability after 13 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.6451290515674822	[504]	[247,115]	-6	hSpCas9	negative selection	970867
49872984	49873007	19	+	26627737	GBM cells	viability after 13 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.017288260507356545	[377]	[238,181]	0	hSpCas9	negative selection	970868
49873133	49873156	19	-	26627737	GBM cells	viability after 13 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.21432663910464547	[289]	[144,127]	-3	hSpCas9	negative selection	970869
49876599	49876622	19	+	26627737	GBM cells	viability after 13 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.12915829688360714	[588]	[402,305]	1	hSpCas9	negative selection	970870
49876627	49876650	19	-	26627737	GBM cells	viability after 13 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.38585574509804493	[258]	[176,188]	5	hSpCas9	negative selection	970871
49869948	49869971	19	+	26627737	GBM cells	viability after 21 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.37385930942742995	[355]	[154,143]	-3	hSpCas9	negative selection	1053181
49870038	49870061	19	+	26627737	GBM cells	viability after 21 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-1.4068840314448894	[504]	[115,91]	-8	hSpCas9	negative selection	1053182
49872984	49873007	19	+	26627737	GBM cells	viability after 21 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.7882694073337264	[377]	[120,116]	-6	hSpCas9	negative selection	1053183
49873133	49873156	19	-	26627737	GBM cells	viability after 21 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.47963869287833616	[289]	[124,101]	-4	hSpCas9	negative selection	1053184
49876599	49876622	19	+	26627737	GBM cells	viability after 21 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.3211238478987082	[588]	[416,383]	3	hSpCas9	negative selection	1053185
49876627	49876650	19	-	26627737	GBM cells	viability after 21 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.3960190396400767	[258]	[204,166]	4	hSpCas9	negative selection	1053186
49869948	49869971	19	+	26627737	RPE1	viability after 9 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.47693829438555435	[1744]	[154,698]	-3	hSpCas9	negative selection	1135496
49870038	49870061	19	+	26627737	RPE1	viability after 9 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-1.1274539837452928	[2249]	[190,491]	-7	hSpCas9	negative selection	1135497
49872984	49873007	19	+	26627737	RPE1	viability after 9 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.47401282755843666	[1410]	[613,612]	3	hSpCas9	negative selection	1135498
49873133	49873156	19	-	26627737	RPE1	viability after 9 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.3464915822841401	[1314]	[404,218]	-2	hSpCas9	negative selection	1135499
49876599	49876622	19	+	26627737	RPE1	viability after 9 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	-0.18297145003306392	[2179]	[419,834]	-1	hSpCas9	negative selection	1135500
49876627	49876650	19	-	26627737	RPE1	viability after 9 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.43357875975620214	[595]	[90,198]	-3	hSpCas9	negative selection	1135501
49869948	49869971	19	+	26627737	RPE1	viability after 12 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.388278382325278	[1744]	[228,494]	-3	hSpCas9	negative selection	1217811
49870038	49870061	19	+	26627737	RPE1	viability after 12 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.8165720323358964	[2249]	[248,442]	-5	hSpCas9	negative selection	1217812
49872984	49873007	19	+	26627737	RPE1	viability after 12 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.2473903302929107	[1410]	[398,503]	1	hSpCas9	negative selection	1217813
49873133	49873156	19	-	26627737	RPE1	viability after 12 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.04158607829329397	[1314]	[435,286]	0	hSpCas9	negative selection	1217814
49876599	49876622	19	+	26627737	RPE1	viability after 12 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.1290215741163021	[2179]	[571,712]	0	hSpCas9	negative selection	1217815
49876627	49876650	19	-	26627737	RPE1	viability after 12 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.7847850186928584	[595]	[56,130]	-5	hSpCas9	negative selection	1217816
49869948	49869971	19	+	26627737	RPE1	viability after 15 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.31328919907514063	[1744]	[128,655]	-2	hSpCas9	negative selection	1300126
49870038	49870061	19	+	26627737	RPE1	viability after 15 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.5595187589075996	[2249]	[354,505]	-4	hSpCas9	negative selection	1300127
49872984	49873007	19	+	26627737	RPE1	viability after 15 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.7324463934167681	[1410]	[541,779]	4	hSpCas9	negative selection	1300128
49873133	49873156	19	-	26627737	RPE1	viability after 15 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.3357778922071205	[1314]	[280,307]	-2	hSpCas9	negative selection	1300129
49876599	49876622	19	+	26627737	RPE1	viability after 15 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.09259274847485632	[2179]	[710,605]	0	hSpCas9	negative selection	1300130
49876627	49876650	19	-	26627737	RPE1	viability after 15 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-1.4685027446517496	[595]	[8,110]	-7	hSpCas9	negative selection	1300131
49869948	49869971	19	+	26627737	RPE1	viability after 18 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.35123618652751687	[1744]	[96,659]	-2	hSpCas9	negative selection	1382441
49870038	49870061	19	+	26627737	RPE1	viability after 18 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.9179936186730147	[2249]	[360,278]	-5	hSpCas9	negative selection	1382442
49872984	49873007	19	+	26627737	RPE1	viability after 18 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.0244683824168832	[1410]	[587,973]	6	hSpCas9	negative selection	1382443
49873133	49873156	19	-	26627737	RPE1	viability after 18 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.17101605387375618	[1314]	[364,261]	-1	hSpCas9	negative selection	1382444
49876599	49876622	19	+	26627737	RPE1	viability after 18 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	-0.3617181740553548	[2179]	[467,446]	-2	hSpCas9	negative selection	1382445
49876627	49876650	19	-	26627737	RPE1	viability after 18 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-2.4283187938530224	[595]	[40,17]	-8	hSpCas9	negative selection	1382446
49869948	49869971	19	+	26627737	HeLa	viability after 8 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.8942577705708205	[388]	[446,285,244]	7	hSpCas9	negative selection	1464756
49870038	49870061	19	+	26627737	HeLa	viability after 8 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.24158296208204844	[1430]	[611,566,426]	-2	hSpCas9	negative selection	1464757
49872984	49873007	19	+	26627737	HeLa	viability after 8 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.798999465865742	[605]	[620,582,224]	6	hSpCas9	negative selection	1464758
49873133	49873156	19	-	26627737	HeLa	viability after 8 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.3351346904623948	[287]	[130,70,258]	3	hSpCas9	negative selection	1464759
49876599	49876622	19	+	26627737	HeLa	viability after 8 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.33494738008417624	[1083]	[431,988,345]	3	hSpCas9	negative selection	1464760
49876627	49876650	19	-	26627737	HeLa	viability after 8 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.8516545527646692	[410]	[293,361,306]	7	hSpCas9	negative selection	1464761
49869948	49869971	19	+	26627737	HeLa	viability after 12 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	1.348816491566105	[388]	[304,525,381]	8	hSpCas9	negative selection	1547071
49870038	49870061	19	+	26627737	HeLa	viability after 12 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.24801869866424853	[1430]	[788,444,273]	-2	hSpCas9	negative selection	1547072
49872984	49873007	19	+	26627737	HeLa	viability after 12 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.639682738457072	[605]	[461,263,459]	5	hSpCas9	negative selection	1547073
49873133	49873156	19	-	26627737	HeLa	viability after 12 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.3607057673371666	[287]	[43,287,108]	3	hSpCas9	negative selection	1547074
49876599	49876622	19	+	26627737	HeLa	viability after 12 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.4505505206638478	[1083]	[402,748,663]	4	hSpCas9	negative selection	1547075
49876627	49876650	19	-	26627737	HeLa	viability after 12 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	1.1383696599307802	[410]	[357,394,365]	7	hSpCas9	negative selection	1547076
49869948	49869971	19	+	26627737	HeLa	viability after 15 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	1.7419505217159	[388]	[676,527,369]	9	hSpCas9	negative selection	1629386
49870038	49870061	19	+	26627737	HeLa	viability after 15 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.33833458760995194	[1430]	[409,318,669]	-3	hSpCas9	negative selection	1629387
49872984	49873007	19	+	26627737	HeLa	viability after 15 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.44615232168164987	[605]	[285,446,270]	3	hSpCas9	negative selection	1629388
49873133	49873156	19	-	26627737	HeLa	viability after 15 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.6276453752695721	[287]	[266,206,58]	5	hSpCas9	negative selection	1629389
49876599	49876622	19	+	26627737	HeLa	viability after 15 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.29818514753071046	[1083]	[448,589,593]	2	hSpCas9	negative selection	1629390
49876627	49876650	19	-	26627737	HeLa	viability after 15 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.6235091955961074	[410]	[432,68,269]	5	hSpCas9	negative selection	1629391
49869948	49869971	19	+	26627737	HeLa	viability after 18 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	1.760587803212143	[388]	[470,432,369]	9	hSpCas9	negative selection	1711701
49870038	49870061	19	+	26627737	HeLa	viability after 18 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.34933618321141924	[1430]	[273,256,669]	-3	hSpCas9	negative selection	1711702
49872984	49873007	19	+	26627737	HeLa	viability after 18 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.4274990862430199	[605]	[181,371,270]	3	hSpCas9	negative selection	1711703
49873133	49873156	19	-	26627737	HeLa	viability after 18 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.6404064767272671	[287]	[188,162,58]	5	hSpCas9	negative selection	1711704
49876599	49876622	19	+	26627737	HeLa	viability after 18 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.30133567884949786	[1083]	[295,497,593]	2	hSpCas9	negative selection	1711705
49876627	49876650	19	-	26627737	HeLa	viability after 18 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.6083645288370337	[410]	[286,54,269]	5	hSpCas9	negative selection	1711706
49869948	49869971	19	+	26627737	HCT116	viability after 6 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.24766897005513522	[1408]	[134,214]	-1	hSpCas9	negative selection	1794016
49870038	49870061	19	+	26627737	HCT116	viability after 6 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	0.4892537236947968	[977]	[501,57]	2	hSpCas9	negative selection	1794017
49872984	49873007	19	+	26627737	HCT116	viability after 6 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.123018365464925	[802]	[185,323]	6	hSpCas9	negative selection	1794018
49873133	49873156	19	-	26627737	HCT116	viability after 6 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.6125473157191773	[800]	[207,183]	3	hSpCas9	negative selection	1794019
49876599	49876622	19	+	26627737	HCT116	viability after 6 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.3067148462502052	[1860]	[493,288]	1	hSpCas9	negative selection	1794020
49876627	49876650	19	-	26627737	HCT116	viability after 6 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	1.0506074099447291	[685]	[428,109]	6	hSpCas9	negative selection	1794021
49869948	49869971	19	+	26627737	HCT116	viability after 8 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.10159594120164939	[484]	[301,182,262]	-1	hSpCas9	negative selection	1876331
49870038	49870061	19	+	26627737	HCT116	viability after 8 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	0.05901796752404409	[649]	[405,426,287]	0	hSpCas9	negative selection	1876332
49872984	49873007	19	+	26627737	HCT116	viability after 8 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.1492100135337109	[353]	[467,435,394]	8	hSpCas9	negative selection	1876333
49873133	49873156	19	-	26627737	HCT116	viability after 8 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.1494484955783619	[296]	[206,155,181]	1	hSpCas9	negative selection	1876334
49876599	49876622	19	+	26627737	HCT116	viability after 8 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.2167557035650891	[790]	[550,432,535]	2	hSpCas9	negative selection	1876335
49876627	49876650	19	-	26627737	HCT116	viability after 8 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.12559858388705425	[455]	[197,182,437]	1	hSpCas9	negative selection	1876336
49869948	49869971	19	+	26627737	HCT116	viability after 9 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-1.508612462392181	[1408]	[110,148]	-8	hSpCas9	negative selection	1958646
49870038	49870061	19	+	26627737	HCT116	viability after 9 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	0.07562637050727206	[977]	[444,140]	0	hSpCas9	negative selection	1958647
49872984	49873007	19	+	26627737	HCT116	viability after 9 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.9304189815188175	[802]	[454,371]	6	hSpCas9	negative selection	1958648
49873133	49873156	19	-	26627737	HCT116	viability after 9 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.49599408540674383	[800]	[173,133]	-4	hSpCas9	negative selection	1958649
49876599	49876622	19	+	26627737	HCT116	viability after 9 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.8627456025336382	[1860]	[1092,753]	6	hSpCas9	negative selection	1958650
49876627	49876650	19	-	26627737	HCT116	viability after 9 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.7602648104066747	[685]	[302,315]	5	hSpCas9	negative selection	1958651
49869948	49869971	19	+	26627737	HCT116	viability after 12 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.4263144865175671	[484]	[287,370,373]	4	hSpCas9	negative selection	2040961
49870038	49870061	19	+	26627737	HCT116	viability after 12 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.348661963766533	[649]	[250,338,217]	-4	hSpCas9	negative selection	2040962
49872984	49873007	19	+	26627737	HCT116	viability after 12 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.5194541503918397	[353]	[655,523,408]	9	hSpCas9	negative selection	2040963
49873133	49873156	19	-	26627737	HCT116	viability after 12 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.36105625764269655	[296]	[136,153,72]	-4	hSpCas9	negative selection	2040964
49876599	49876622	19	+	26627737	HCT116	viability after 12 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.30730733111017194	[790]	[668,491,367]	3	hSpCas9	negative selection	2040965
49876627	49876650	19	-	26627737	HCT116	viability after 12 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.6620504331676658	[455]	[189,111,147]	-6	hSpCas9	negative selection	2040966
49869948	49869971	19	+	26627737	HCT116	viability after 15 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.35563398471729546	[484]	[445,352,281]	3	hSpCas9	negative selection	2123276
49870038	49870061	19	+	26627737	HCT116	viability after 15 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.03163088592433039	[649]	[483,339,286]	0	hSpCas9	negative selection	2123277
49872984	49873007	19	+	26627737	HCT116	viability after 15 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.092735796042505	[353]	[434,601,265]	8	hSpCas9	negative selection	2123278
49873133	49873156	19	-	26627737	HCT116	viability after 15 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.016146762430460947	[296]	[268,145,103]	0	hSpCas9	negative selection	2123279
49876599	49876622	19	+	26627737	HCT116	viability after 15 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.28330491554107384	[790]	[675,569,428]	3	hSpCas9	negative selection	2123280
49876627	49876650	19	-	26627737	HCT116	viability after 15 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.8326786602361049	[455]	[227,77,144]	-7	hSpCas9	negative selection	2123281
49869948	49869971	19	+	26627737	HCT116	viability after 18 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.4389755348338794	[484]	[264,258,438]	4	hSpCas9	negative selection	2205591
49870038	49870061	19	+	26627737	HCT116	viability after 18 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.023437408854888764	[649]	[298,317,309]	0	hSpCas9	negative selection	2205592
49872984	49873007	19	+	26627737	HCT116	viability after 18 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.4214972931541658	[353]	[354,528,487]	8	hSpCas9	negative selection	2205593
49873133	49873156	19	-	26627737	HCT116	viability after 18 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.179018261734268	[296]	[172,171,27]	-2	hSpCas9	negative selection	2205594
49876599	49876622	19	+	26627737	HCT116	viability after 18 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.27329168041238505	[790]	[728,296,366]	2	hSpCas9	negative selection	2205595
49876627	49876650	19	-	26627737	HCT116	viability after 18 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.15708577378468563	[455]	[151,131,318]	-1	hSpCas9	negative selection	2205596
49873140	49873163	19	+	24336569	HL60	viability	TCCTCGACCATGGGCAGCATAGG	AKT1S1	ENSG00000204673	1.2092934444523946	[261]	[1281]	8	hSpCas9	negative selection	2247339
49873146	49873169	19	+	24336569	HL60	viability	ACCATGGGCAGCATAGGCACAGG	AKT1S1	ENSG00000204673	0.6588750929654168	[597]	[1997]	5	hSpCas9	negative selection	2247340
49873196	49873219	19	-	24336569	HL60	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-0.6067063897640586	[697]	[969]	-5	hSpCas9	negative selection	2247341
49873208	49873231	19	+	24336569	HL60	viability	GCACCAGCTCCGTGCCAGTCCGG	AKT1S1	ENSG00000204673	-0.4774488573099245	[676]	[1028]	-4	hSpCas9	negative selection	2247342
49873217	49873240	19	-	24336569	HL60	viability	CTTCCGGGCCCGGACTGGCACGG	AKT1S1	ENSG00000204673	0.13443632961380275	[349]	[812]	1	hSpCas9	negative selection	2247343
49873222	49873245	19	-	24336569	HL60	viability	GAGCGCTTCCGGGCCCGGACTGG	AKT1S1	ENSG00000204673	-0.9048355588905073	[667]	[754]	-7	hSpCas9	negative selection	2247344
49873227	49873250	19	-	24336569	HL60	viability	CCGCTGAGCGCTTCCGGGCCCGG	AKT1S1	ENSG00000204673	1.9675733926796584	[93]	[777]	9	hSpCas9	negative selection	2247345
49873253	49873276	19	-	24336569	HL60	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-2.3629357547193663	[755]	[310]	-9	hSpCas9	negative selection	2247346
49873258	49873281	19	+	24336569	HL60	viability	ACGGCCTCCCACAGCTCCTCGGG	AKT1S1	ENSG00000204673	-0.30249097994111485	[527]	[905]	-3	hSpCas9	negative selection	2247347
49873285	49873308	19	-	24336569	HL60	viability	CGCAGGGCGCGGATGGCGTCGGG	AKT1S1	ENSG00000204673	0.27339984422891567	[510]	[1306]	2	hSpCas9	negative selection	2247348
49873140	49873163	19	+	24336569	KBM7	viability	TCCTCGACCATGGGCAGCATAGG	AKT1S1	ENSG00000204673	-0.1899417177535233	[490]	[1173]	-2	hSpCas9	negative selection	2314516
49873146	49873169	19	+	24336569	KBM7	viability	ACCATGGGCAGCATAGGCACAGG	AKT1S1	ENSG00000204673	0.2527567044410197	[1068]	[3473]	2	hSpCas9	negative selection	2314517
49873196	49873219	19	-	24336569	KBM7	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-0.2029189035872602	[348]	[826]	-2	hSpCas9	negative selection	2314518
49873208	49873231	19	+	24336569	KBM7	viability	GCACCAGCTCCGTGCCAGTCCGG	AKT1S1	ENSG00000204673	0.7863027602219506	[401]	[1890]	7	hSpCas9	negative selection	2314519
49873217	49873240	19	-	24336569	KBM7	viability	CTTCCGGGCCCGGACTGGCACGG	AKT1S1	ENSG00000204673	0.9885199182577908	[237]	[1287]	8	hSpCas9	negative selection	2314520
49873222	49873245	19	-	24336569	KBM7	viability	GAGCGCTTCCGGGCCCGGACTGG	AKT1S1	ENSG00000204673	0.7640387531933901	[287]	[1333]	7	hSpCas9	negative selection	2314521
49873227	49873250	19	-	24336569	KBM7	viability	CCGCTGAGCGCTTCCGGGCCCGG	AKT1S1	ENSG00000204673	0.5664568631379787	[178]	[722]	5	hSpCas9	negative selection	2314522
49873253	49873276	19	-	24336569	KBM7	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-4.466637532364567	[761]	[93]	-9	hSpCas9	negative selection	2314523
49873258	49873281	19	+	24336569	KBM7	viability	ACGGCCTCCCACAGCTCCTCGGG	AKT1S1	ENSG00000204673	-0.11367845999544424	[623]	[1572]	-1	hSpCas9	negative selection	2314524
49873285	49873308	19	-	24336569	KBM7	viability	CGCAGGGCGCGGATGGCGTCGGG	AKT1S1	ENSG00000204673	1.348728232994567	[205]	[1430]	9	hSpCas9	negative selection	2314525
49877239	49877262	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCGAACGGATAAGAGAAGAGG	AKT1S1	ENSG00000204673	3.748750193030614	[79,36]	[232,107]	9	dCas9-VP64	positive selection	2405678
49877314	49877337	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCCTAAGCCGGTCAGCTAAGG	AKT1S1	ENSG00000204673	-0.13493625453240488	[22,35]	[3,7]	0	dCas9-VP64	positive selection	2405679
49877270	49877293	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCGCGCCCCGCAGAGAGATGG	AKT1S1	ENSG00000204673	0.7974817597416377	[32,70]	[24,13]	3	dCas9-VP64	positive selection	2405680
49876350	49876373	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGGCCCAGGTAGAGATCCCAGG	AKT1S1	ENSG00000204673	5.662557272074872	[24,271]	[13,3483]	9	dCas9-VP64	positive selection	2419589
49876368	49876391	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTTGCGGTTCCAGAGCGCCTGG	AKT1S1	ENSG00000204673	-0.3634369367453784	[80,172]	[8,34]	-2	dCas9-VP64	positive selection	2419590
49876326	49876349	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACCACGTCCACGGGGTCGGGGG	AKT1S1	ENSG00000204673	-1.7625203439998534	[384,222]	[17,20]	-8	dCas9-VP64	positive selection	2419591
49877239	49877262	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCGAACGGATAAGAGAAGAGG	AKT1S1	ENSG00000204673	4.41120346345393	[164,262]	[71,2809]	9	dCas9-VP64	positive selection	2500933
49877314	49877337	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCCTAAGCCGGTCAGCTAAGG	AKT1S1	ENSG00000204673	-0.1578765103130086	[124,96]	[23,38]	-1	dCas9-VP64	positive selection	2500934
49877270	49877293	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCGCGCCCCGCAGAGAGATGG	AKT1S1	ENSG00000204673	-0.1440883705259522	[136,106]	[29,40]	-1	dCas9-VP64	positive selection	2500935
49876350	49876373	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGGCCCAGGTAGAGATCCCAGG	AKT1S1	ENSG00000204673	1.089834520174336	[173,360]	[39,319]	7	dCas9-VP64	positive selection	2514844
49876368	49876391	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTTGCGGTTCCAGAGCGCCTGG	AKT1S1	ENSG00000204673	-0.0501156564317895	[45,42]	[18,7]	0	dCas9-VP64	positive selection	2514845
49876326	49876349	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACCACGTCCACGGGGTCGGGGG	AKT1S1	ENSG00000204673	0.03371135503561831	[132,136]	[17,69]	0	dCas9-VP64	positive selection	2514846
49873085	49873108	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	0.2616408183380463	[3,4]	[4,3]	5	hSpCas9	positive selection	2969772
49872985	49873008	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.44605595335794207	[4,4]	[3,0]	-6	hSpCas9	positive selection	2969773
49873274	49873297	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	-0.24228216010859072	[3,3]	[1,2]	-3	hSpCas9	positive selection	2969774
49872995	49873018	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.46568625758746207	[1,1]	[1,0]	-6	hSpCas9	positive selection	2969775
49873085	49873108	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	-0.23544222819396934	[3,3]	[2,1]	-3	hSpCas9	positive selection	3037630
49872985	49873008	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.38287196410414137	[4,4]	[3,1]	-5	hSpCas9	positive selection	3037631
49873274	49873297	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	0.15604130828740725	[3,3]	[3,2]	2	hSpCas9	positive selection	3037632
49872995	49873018	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.5841949902986279	[1,1]	[0,0]	-7	hSpCas9	positive selection	3037633
49871804	49871827		+	24336571	A375	resistance to PLX after 7 days	ACACTCACCATCTGTACTCTCGG	AKT1S1	ENSG00000204673	-0.12367104298300369	[25,22]	[20,22]	-4	hSpCas9	positive selection	3112540
49871687	49871710		+	24336571	A375	resistance to PLX after 7 days	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	-0.15597592942981597	[5,5]	[4,4]	-5	hSpCas9	positive selection	3112551
49871811	49871834		-	24336571	A375	resistance to PLX after 7 days	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5600672603815089	[6,5]	[3,3]	-9	hSpCas9	positive selection	3112562
49871804	49871827		+	24336571	A375	resistance to PLX after 14 days	ACACTCACCATCTGTACTCTCGG	AKT1S1	ENSG00000204673	-0.02952710948771864	[28,21]	[10,11]	0	hSpCas9	positive selection	3170333
49871687	49871710		+	24336571	A375	resistance to PLX after 14 days	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	-0.12166083428692565	[3,6]	[1,1]	-1	hSpCas9	positive selection	3170344
49871811	49871834		-	24336571	A375	resistance to PLX after 14 days	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.31193436295005705	[6,5]	[1,1]	-4	hSpCas9	positive selection	3170355
49871804	49871827		+	24336571	A375	viability after 7 days	ACACTCACCATCTGTACTCTCGG	AKT1S1	ENSG00000204673	-0.027367304301580964	[25]	[25,22]	0	hSpCas9	negative selection	3228126
49871687	49871710		+	24336571	A375	viability after 7 days	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.2163605185053099	[4]	[5,5]	3	hSpCas9	negative selection	3228137
49871811	49871834		-	24336571	A375	viability after 7 days	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.6742110084273301	[10]	[6,5]	-7	hSpCas9	negative selection	3228148
49871804	49871827		+	24336571	A375	viability after 14 days	ACACTCACCATCTGTACTCTCGG	AKT1S1	ENSG00000204673	0.07353539224910177	[25]	[28,21]	0	hSpCas9	negative selection	3285919
49871687	49871710		+	24336571	A375	viability after 14 days	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.12801023367202835	[4]	[3,6]	1	hSpCas9	negative selection	3285930
49871811	49871834		-	24336571	A375	viability after 14 days	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.6376278654100043	[10]	[6,5]	-6	hSpCas9	negative selection	3285941
49870018	49870041	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	1.539940986249145	[69,34]	[0,0]	6	hSpCas9	positive selection	3336187
49873115	49873138	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.9105083368137229	[64,97]	[0,0]	4	hSpCas9	positive selection	3336188
49873088	49873111	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	2.1293908779626154	[29,39]	[0,0]	7	hSpCas9	positive selection	3336189
49869942	49869965	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	1.8997742068277512	[40,40]	[0,0]	7	hSpCas9	positive selection	3355440
49871687	49871710	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.23495839841738073	[129,129]	[0,0]	1	hSpCas9	positive selection	3355441
49871811	49871834	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	0.6134700216711103	[99,99]	[0,0]	3	hSpCas9	positive selection	3355442
49873085	49873108	19	-	26780180	HT29	viability (Avana library 4 designs)	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	0.612785930937198	[]	[]	2	hSpCas9	negative selection	3405850
49872984	49873007	19	+	26780180	HT29	viability (Avana library 4 designs)	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.679040380443813	[]	[]	2	hSpCas9	negative selection	3405851
49873274	49873297	19	-	26780180	HT29	viability (Avana library 4 designs)	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	0.335957574588502	[]	[]	1	hSpCas9	negative selection	3405852
49872994	49873017	19	+	26780180	HT29	viability (Avana library 4 designs)	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.33579796318966	[]	[]	1	hSpCas9	negative selection	3405853
49872994	49873017	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-4.18519539716223	[]	[]	-5	hSpCas9	negative selection	3478070
49873274	49873297	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	7.38313514388667	[]	[]	9	hSpCas9	negative selection	3478071
49872984	49873007	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	4.69445944817467	[]	[]	7	hSpCas9	negative selection	3478072
49873085	49873108	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	6.7141141642595	[]	[]	9	hSpCas9	negative selection	3478073
49872930	49872953	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.351728166898684	[]	[]	0	hSpCas9	negative selection	3478074
49872980	49873003	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-1.82944229179615	[]	[]	-2	hSpCas9	negative selection	3478075
49872994	49873017	19	+	26780180	A375	viability (Avana lentiGuide)	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-2.73454735788167	[]	[]	-5	hSpCas9	negative selection	3586729
49873274	49873297	19	-	26780180	A375	viability (Avana lentiGuide)	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	3.70035640914043	[]	[]	3	hSpCas9	negative selection	3586730
49872984	49873007	19	+	26780180	A375	viability (Avana lentiGuide)	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	2.94929020027895	[]	[]	3	hSpCas9	negative selection	3586731
49873085	49873108	19	-	26780180	A375	viability (Avana lentiGuide)	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	-1.05671134561787	[]	[]	-2	hSpCas9	negative selection	3586732
49872930	49872953	19	+	26780180	A375	viability (Avana lentiGuide)	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-2.32865630473279	[]	[]	-4	hSpCas9	negative selection	3586733
49872980	49873003	19	-	26780180	A375	viability (Avana lentiGuide)	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-1.88120942612167	[]	[]	-3	hSpCas9	negative selection	3586734
49872994	49873017	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.4941689577792926	[2]	[1,0]	-6	hSpCas9	positive selection	3695388
49873274	49873297	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	0.25491483983650465	[5]	[6,5]	7	hSpCas9	positive selection	3695389
49872984	49873007	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.14860993277313495	[5]	[5,5]	4	hSpCas9	positive selection	3695390
49873085	49873108	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	0.3569593320166242	[5]	[6,6]	9	hSpCas9	positive selection	3695391
49872930	49872953	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.16815660114738834	[4]	[4,2]	-3	hSpCas9	positive selection	3695392
49872980	49873003	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.059106663006637805	[3]	[3,3]	-1	hSpCas9	positive selection	3695393
49872994	49873017	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.7469998897568475	[2]	[0,1]	-7	hSpCas9	positive selection	3803995
49873274	49873297	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGCGTCGGGGCGCCCCGAGG	AKT1S1	ENSG00000204673	-0.08839686894475199	[6]	[4,4]	-1	hSpCas9	positive selection	3803996
49872984	49873007	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.21355348198708374	[6]	[4,3]	-3	hSpCas9	positive selection	3803997
49873085	49873108	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGACATCGCACTGGCCCACAGGG	AKT1S1	ENSG00000204673	0.155040699156651	[5]	[4,5]	3	hSpCas9	positive selection	3803998
49872930	49872953	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.07282834220464005	[5]	[4,4]	1	hSpCas9	positive selection	3803999
49872980	49873003	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.0013762785306847408	[4]	[5,2]	0	hSpCas9	positive selection	3804000
49873115	49873138	19	+	26780180	A375	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.876890707330185	[]	[]	3	hSpCas9	negative selection	3912403
49869942	49869965	19	+	26780180	A375	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.709452151587797	[]	[]	2	hSpCas9	negative selection	3912404
49870018	49870041	19	+	26780180	A375	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.913367995567505	[]	[]	4	hSpCas9	negative selection	3912405
49871687	49871710	19	+	26780180	A375	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	1.00131256311304	[]	[]	4	hSpCas9	negative selection	3912406
49871811	49871834	19	-	26780180	A375	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	1.1283080508877	[]	[]	5	hSpCas9	negative selection	3912407
49873088	49873111	19	+	26780180	A375	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.440942740503957	[]	[]	1	hSpCas9	negative selection	3912408
49873115	49873138	19	+	26780180	HT29	viability (GeCKOv2 library)	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	1.63708188815626	[]	[]	8	hSpCas9	negative selection	4020369
49869942	49869965	19	+	26780180	HT29	viability (GeCKOv2 library)	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	1.1859218057822	[]	[]	6	hSpCas9	negative selection	4020370
49870018	49870041	19	+	26780180	HT29	viability (GeCKOv2 library)	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.564201749139316	[]	[]	2	hSpCas9	negative selection	4020371
49871687	49871710	19	+	26780180	HT29	viability (GeCKOv2 library)	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	1.58306834795352	[]	[]	8	hSpCas9	negative selection	4020372
49871811	49871834	19	-	26780180	HT29	viability (GeCKOv2 library)	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	1.57328252007202	[]	[]	8	hSpCas9	negative selection	4020373
49873088	49873111	19	+	26780180	HT29	viability (GeCKOv2 library)	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.705414600891568	[]	[]	2	hSpCas9	negative selection	4020374
49871804	49871827	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACTCACCATCTGTACTCTCGG	AKT1S1	ENSG00000204673	0.09727295548837189	[4]	[3,3]	2	hSpCas9	positive selection	4135272
49871687	49871710	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	-0.48939094370271663	[2]	[1,0]	-8	hSpCas9	positive selection	4135283
49871811	49871834	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.45968310496679143	[3]	[1,0]	-8	hSpCas9	positive selection	4135294
49871804	49871827	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACTCACCATCTGTACTCTCGG	AKT1S1	ENSG00000204673	-0.20007295576861422	[5]	[4,3,0,0]	-3	hSpCas9	positive selection	4199294
49871687	49871710	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	-0.002945716359980144	[2]	[0,3,0,0]	0	hSpCas9	positive selection	4199305
49871811	49871834	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	0.14075678128860034	[3]	[1,0,4,0]	1	hSpCas9	positive selection	4199316
49870018	49870041	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	-0.0035881500315382286	[1]	[2,0]	0	hSpCas9	positive selection	4255211
49873115	49873138	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.049521049116871885	[2]	[2,0]	1	hSpCas9	positive selection	4255212
49873088	49873111	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.40365485769653286	[1]	[1,1]	8	hSpCas9	positive selection	4255213
49869942	49869965	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.41863645666865157	[1]	[0,0]	-7	hSpCas9	positive selection	4319493
49871687	49871710	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	-0.4083084891695372	[1]	[0,0]	-7	hSpCas9	positive selection	4319494
49871811	49871834	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.31291157773205847	[2]	[1,0]	-6	hSpCas9	positive selection	4319495
49871699	49871721	19	-	27760321	OCIAML3	viability	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.4044156034599763	[628,480]	[438,740]	5	hSpCas9	negative selection	4377239
49871826	49871848	19	+	27760321	OCIAML3	viability	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.20085634145055437	[357,317]	[213,249]	-2	hSpCas9	negative selection	4377240
49872993	49873015	19	+	27760321	OCIAML3	viability	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	0.38595928378914396	[628,592]	[548,723]	4	hSpCas9	negative selection	4377241
49873094	49873116	19	-	27760321	OCIAML3	viability	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-0.682204899835672	[507,453]	[234,232]	-6	hSpCas9	negative selection	4377242
49873132	49873154	19	+	27760321	OCIAML3	viability	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.6269807421759764	[933,756]	[954,1094]	7	hSpCas9	negative selection	4377243
49871699	49871721	19	-	27760321	OCIAML2	viability	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7388629410025582	[628,480]	[727,763]	8	hSpCas9	negative selection	4460702
49871826	49871848	19	+	27760321	OCIAML2	viability	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.40485865364649226	[357,317]	[197,216]	-5	hSpCas9	negative selection	4460703
49872993	49873015	19	+	27760321	OCIAML2	viability	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	0.2828790365814344	[628,592]	[433,822]	4	hSpCas9	negative selection	4460704
49873094	49873116	19	-	27760321	OCIAML2	viability	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-0.3069348088523241	[507,453]	[295,337]	-4	hSpCas9	negative selection	4460705
49873132	49873154	19	+	27760321	OCIAML2	viability	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	-0.102279889169823	[933,756]	[581,701]	-1	hSpCas9	negative selection	4460706
49871699	49871721	19	-	27760321	MV411	viability	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.5148774188747817	[628,480]	[649,322]	3	hSpCas9	negative selection	4544165
49871826	49871848	19	+	27760321	MV411	viability	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.16116310485130508	[357,317]	[147,275]	-1	hSpCas9	negative selection	4544166
49872993	49873015	19	+	27760321	MV411	viability	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	-0.2761212443733001	[628,592]	[156,597]	-2	hSpCas9	negative selection	4544167
49873094	49873116	19	-	27760321	MV411	viability	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	0.2691316427635551	[507,453]	[383,378]	2	hSpCas9	negative selection	4544168
49873132	49873154	19	+	27760321	MV411	viability	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.3802368978078686	[933,756]	[412,1186]	2	hSpCas9	negative selection	4544169
49871699	49871721	19	-	27760321	HL60	viability	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7814226717166666	[628,480]	[815,727]	8	hSpCas9	negative selection	4627628
49871826	49871848	19	+	27760321	HL60	viability	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	0.012553974716358385	[357,317]	[230,327]	0	hSpCas9	negative selection	4627629
49872993	49873015	19	+	27760321	HL60	viability	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	-0.024508345091804162	[628,592]	[511,468]	0	hSpCas9	negative selection	4627630
49873094	49873116	19	-	27760321	HL60	viability	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-0.1795404647681518	[507,453]	[378,311]	-2	hSpCas9	negative selection	4627631
49873132	49873154	19	+	27760321	HL60	viability	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.38347724646861725	[933,756]	[835,959]	5	hSpCas9	negative selection	4627632
49871699	49871721	19	-	27760321	HT1080	viability	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	1.6021081709086924	[480,375]	[481,557]	8	hSpCas9	negative selection	4711091
49871826	49871848	19	+	27760321	HT1080	viability	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-1.0711316184875548	[317,247]	[77,26]	-4	hSpCas9	negative selection	4711092
49872993	49873015	19	+	27760321	HT1080	viability	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	1.0321878390861459	[592,462]	[433,425]	5	hSpCas9	negative selection	4711093
49873094	49873116	19	-	27760321	HT1080	viability	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-1.1424159381555499	[453,353]	[112,28]	-4	hSpCas9	negative selection	4711094
49873132	49873154	19	+	27760321	HT1080	viability	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.6008959528996785	[756,590]	[506,297]	3	hSpCas9	negative selection	4711095
49871699	49871721	19	-	27760321	HT29	viability after 7 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7026260829730122	[480,375]	[914,484,1278]	9	hSpCas9	negative selection	4794554
49871826	49871848	19	+	27760321	HT29	viability after 7 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	0.09147255606907173	[317,247]	[512,397,272]	1	hSpCas9	negative selection	4794555
49872993	49873015	19	+	27760321	HT29	viability after 7 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	-0.01687716033980724	[592,462]	[718,634,664]	0	hSpCas9	negative selection	4794556
49873094	49873116	19	-	27760321	HT29	viability after 7 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	0.34046682836770903	[453,353]	[745,657,582]	5	hSpCas9	negative selection	4794557
49873132	49873154	19	+	27760321	HT29	viability after 7 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.3064653077602435	[756,590]	[1496,827,952]	5	hSpCas9	negative selection	4794558
49871699	49871721	19	-	27760321	HT29	viability after 25 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.41450356879339006	[480,375]	[644,545,779]	4	hSpCas9	negative selection	4878017
49871826	49871848	19	+	27760321	HT29	viability after 25 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.14389146571343076	[317,247]	[330,158,395]	-1	hSpCas9	negative selection	4878018
49872993	49873015	19	+	27760321	HT29	viability after 25 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	-0.09821468465447353	[592,462]	[481,618,597]	-1	hSpCas9	negative selection	4878019
49873094	49873116	19	-	27760321	HT29	viability after 25 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	0.0794798585745097	[453,353]	[238,530,733]	0	hSpCas9	negative selection	4878020
49873132	49873154	19	+	27760321	HT29	viability after 25 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.41327290241101067	[756,590]	[1124,888,1058]	4	hSpCas9	negative selection	4878021
49871699	49871721	19	-	27760321	HT29	viability after 22 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7577826266261443	[480,375]	[898,919,690]	8	hSpCas9	negative selection	4961480
49871826	49871848	19	+	27760321	HT29	viability after 22 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.38494063237900167	[317,247]	[152,373,226]	-4	hSpCas9	negative selection	4961481
49872993	49873015	19	+	27760321	HT29	viability after 22 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	-0.008423509202931778	[592,462]	[455,512,857]	0	hSpCas9	negative selection	4961482
49873094	49873116	19	-	27760321	HT29	viability after 22 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	0.17668225139276864	[453,353]	[319,550,719]	1	hSpCas9	negative selection	4961483
49873132	49873154	19	+	27760321	HT29	viability after 22 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.331241421938526	[756,590]	[932,833,1176]	3	hSpCas9	negative selection	4961484
49871699	49871721	19	-	27760321	HT29	viability after 19 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.19365295010847078	[480,375]	[708,648,346]	1	hSpCas9	negative selection	5044943
49871826	49871848	19	+	27760321	HT29	viability after 19 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.031101521522616193	[317,247]	[370,302,282]	0	hSpCas9	negative selection	5044944
49872993	49873015	19	+	27760321	HT29	viability after 19 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	0.34488197931735776	[592,462]	[450,559,1237]	3	hSpCas9	negative selection	5044945
49873094	49873116	19	-	27760321	HT29	viability after 19 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-0.13197501875146453	[453,353]	[209,705,329]	-1	hSpCas9	negative selection	5044946
49873132	49873154	19	+	27760321	HT29	viability after 19 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.4419793140142134	[756,590]	[902,887,1323]	4	hSpCas9	negative selection	5044947
49871699	49871721	19	-	27760321	HT29	viability after 16 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7314094369955424	[480,375]	[753,717,913]	8	hSpCas9	negative selection	5128406
49871826	49871848	19	+	27760321	HT29	viability after 16 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	0.21012160822378492	[317,247]	[584,187,350]	2	hSpCas9	negative selection	5128407
49872993	49873015	19	+	27760321	HT29	viability after 16 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	0.23269280594181874	[592,462]	[910,532,662]	2	hSpCas9	negative selection	5128408
49873094	49873116	19	-	27760321	HT29	viability after 16 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-0.18936225370886198	[453,353]	[547,257,400]	-2	hSpCas9	negative selection	5128409
49873132	49873154	19	+	27760321	HT29	viability after 16 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.26239107743038104	[756,590]	[963,903,850]	3	hSpCas9	negative selection	5128410
49871699	49871721	19	-	27760321	HT29	viability after 13 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7712404858179875	[480,375]	[871,1074,612]	8	hSpCas9	negative selection	5211869
49871826	49871848	19	+	27760321	HT29	viability after 13 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-0.1975153869972891	[317,247]	[212,393,253]	-2	hSpCas9	negative selection	5211870
49872993	49873015	19	+	27760321	HT29	viability after 13 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	-0.16125894931487478	[592,462]	[478,473,681]	-2	hSpCas9	negative selection	5211871
49873094	49873116	19	-	27760321	HT29	viability after 13 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	0.2671253925801145	[453,353]	[580,481,624]	3	hSpCas9	negative selection	5211872
49873132	49873154	19	+	27760321	HT29	viability after 13 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.6549234783613769	[756,590]	[1623,1154,931]	8	hSpCas9	negative selection	5211873
49871699	49871721	19	-	27760321	HT29	viability after 10 days	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.7796597288607952	[480,375]	[856,855,1037]	9	hSpCas9	negative selection	5295332
49871826	49871848	19	+	27760321	HT29	viability after 10 days	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	0.3049788206014164	[317,247]	[621,304,379]	4	hSpCas9	negative selection	5295333
49872993	49873015	19	+	27760321	HT29	viability after 10 days	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	0.0029850783719465035	[592,462]	[728,594,655]	0	hSpCas9	negative selection	5295334
49873094	49873116	19	-	27760321	HT29	viability after 10 days	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	0.04087434454309133	[453,353]	[291,528,730]	0	hSpCas9	negative selection	5295335
49873132	49873154	19	+	27760321	HT29	viability after 10 days	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	0.3225117491013658	[756,590]	[993,1220,948]	4	hSpCas9	negative selection	5295336
49871699	49871721	19	-	27760321	MOLM13	viability	TCAGATGGCAGCCTGAGCGAGG	AKT1S1	ENSG00000204673	0.16014616981856694	[628,480]	[451,257]	1	hSpCas9	negative selection	5378795
49871826	49871848	19	+	27760321	MOLM13	viability	GGGTCTGACTCACAGAAGGGGG	AKT1S1	ENSG00000204673	-1.0468251865792053	[357,317]	[163,30]	-6	hSpCas9	negative selection	5378796
49872993	49873015	19	+	27760321	MOLM13	viability	CTCTCTGGCCAGGGTAGGCCGG	AKT1S1	ENSG00000204673	1.6124581736721697	[628,592]	[1525,653]	9	hSpCas9	negative selection	5378797
49873094	49873116	19	-	27760321	MOLM13	viability	TGCCTCCACGACATCGCACTGG	AKT1S1	ENSG00000204673	-1.134864947651469	[507,453]	[137,110]	-6	hSpCas9	negative selection	5378798
49873132	49873154	19	+	27760321	MOLM13	viability	GCCAGGGCTCCTCGACCATGGG	AKT1S1	ENSG00000204673	1.2027487831491337	[933,756]	[1694,578]	8	hSpCas9	negative selection	5378799
49877332	49877355	19	+	27661255	K562	viability	GGCCATGCCCTCGAGCAAAATGG	AKT1S1	ENSG00000204673	-0.04747967306641959	[579,648]	[527,427]	-2	dCas9-KRAB	negative selection	5461701
49876592	49876615	19	-	27661255	K562	viability	GGCTACGGGCACGTGAGTGGAGG	AKT1S1	ENSG00000204673	0.17242573649712506	[485,676]	[636,420]	6	dCas9-KRAB	negative selection	5461702
49876595	49876618	19	-	27661255	K562	viability	GCTGGCTACGGGCACGTGAGTGG	AKT1S1	ENSG00000204673	0.1018840363331418	[376,431]	[407,292]	3	dCas9-KRAB	negative selection	5461703
49870018	49870041	19	+	27260156	BXPC3	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.38097168525708947	[166]	[214,204,166,335]	7	hSpCas9	negative selection	5527671
49873115	49873138	19	+	27260156	BXPC3	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.6548125085891139	[237]	[417,436,287,416]	9	hSpCas9	negative selection	5527672
49873088	49873111	19	+	27260156	BXPC3	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.036816079876852204	[122]	[102,106,136,191]	0	hSpCas9	negative selection	5527673
49869942	49869965	19	+	27260156	BXPC3	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.07540026191816862	[89]	[21,105,146,88]	-2	hSpCas9	negative selection	5591953
49871687	49871710	19	+	27260156	BXPC3	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.8263329523233439	[165]	[236,293,359,352]	9	hSpCas9	negative selection	5591954
49871811	49871834	19	-	27260156	BXPC3	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.29458164125839437	[321]	[330,213,268,279]	-6	hSpCas9	negative selection	5591955
49870018	49870041	19	+	27260156	A673	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5134051131937306	[166]	[245,272,313,307]	9	hSpCas9	negative selection	5648922
49873115	49873138	19	+	27260156	A673	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.43509779455388387	[237]	[450,388,422,282]	8	hSpCas9	negative selection	5648923
49873088	49873111	19	+	27260156	A673	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.29208392235772473	[122]	[185,174,162,200]	7	hSpCas9	negative selection	5648924
49869942	49869965	19	+	27260156	A673	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.013947651127533156	[89]	[107,86,153,85]	0	hSpCas9	negative selection	5713204
49871687	49871710	19	+	27260156	A673	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.48507733921884877	[165]	[285,262,222,348]	9	hSpCas9	negative selection	5713205
49871811	49871834	19	-	27260156	A673	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.2874468631747574	[321]	[325,259,374,306]	-6	hSpCas9	negative selection	5713206
49870018	49870041	19	+	27260156	A375	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.8799006844469981	[166]	[297,385,378,372]	9	hSpCas9	negative selection	5770173
49873115	49873138	19	+	27260156	A375	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.4542995346032712	[237]	[396,376,379,368]	6	hSpCas9	negative selection	5770174
49873088	49873111	19	+	27260156	A375	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.08859544906978489	[122]	[157,151,217,89]	1	hSpCas9	negative selection	5770175
49869942	49869965	19	+	27260156	A375	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.5126516207716156	[89]	[96,84,295,115]	7	hSpCas9	negative selection	5834455
49871687	49871710	19	+	27260156	A375	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	1.0120462438827804	[165]	[436,410,421,305]	9	hSpCas9	negative selection	5834456
49871811	49871834	19	-	27260156	A375	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.4229366331805442	[321]	[205,401,226,299]	-5	hSpCas9	negative selection	5834457
49870018	49870041	19	+	27260156	COLO741	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5811789172925697	[166]	[389,283,290]	9	hSpCas9	negative selection	5891424
49873115	49873138	19	+	27260156	COLO741	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.4445380579518672	[237]	[393,431,412]	8	hSpCas9	negative selection	5891425
49873088	49873111	19	+	27260156	COLO741	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.13081760863998992	[122]	[121,193,193]	2	hSpCas9	negative selection	5891426
49869942	49869965	19	+	27260156	COLO741	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.18966980271400313	[89]	[165,167,66]	4	hSpCas9	negative selection	5955706
49871687	49871710	19	+	27260156	COLO741	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.06132670580080268	[165]	[274,242,154]	1	hSpCas9	negative selection	5955707
49871811	49871834	19	-	27260156	COLO741	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.8215559718052494	[321]	[241,242,214]	-9	hSpCas9	negative selection	5955708
49870018	49870041	19	+	27260156	CAL120	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.8219151394289463	[166]	[440,359,312]	9	hSpCas9	negative selection	6012675
49873115	49873138	19	+	27260156	CAL120	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.05348943160455977	[237]	[294,313,310]	0	hSpCas9	negative selection	6012676
49873088	49873111	19	+	27260156	CAL120	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.32059323576919696	[122]	[437,64,108]	5	hSpCas9	negative selection	6012677
49869942	49869965	19	+	27260156	CAL120	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.19124300874485467	[89]	[154,124,107]	3	hSpCas9	negative selection	6076957
49871687	49871710	19	+	27260156	CAL120	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	1.0588465374810831	[165]	[598,442,276]	9	hSpCas9	negative selection	6076958
49871811	49871834	19	-	27260156	CAL120	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	0.2038326936465556	[321]	[705,471,246]	3	hSpCas9	negative selection	6076959
49870018	49870041	19	+	27260156	CADOES1	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	1.0485824731074085	[166]	[275,376,217,417]	9	hSpCas9	negative selection	6133926
49873115	49873138	19	+	27260156	CADOES1	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.6091349085490465	[237]	[315,218,358,460]	8	hSpCas9	negative selection	6133927
49873088	49873111	19	+	27260156	CADOES1	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.30892785460839356	[122]	[67,181,101,217]	5	hSpCas9	negative selection	6133928
49869942	49869965	19	+	27260156	CADOES1	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.8313116689020328	[89]	[124,135,230,101]	9	hSpCas9	negative selection	6198208
49871687	49871710	19	+	27260156	CADOES1	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.7349229891867698	[165]	[253,269,191,313]	9	hSpCas9	negative selection	6198209
49871811	49871834	19	-	27260156	CADOES1	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	0.5712894507917112	[321]	[472,406,397,503]	8	hSpCas9	negative selection	6198210
49870018	49870041	19	+	27260156	EWS502	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.9885500072192368	[166]	[283,528,298,285]	9	hSpCas9	negative selection	6255177
49873115	49873138	19	+	27260156	EWS502	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5056550135131287	[237]	[214,374,369,496]	8	hSpCas9	negative selection	6255178
49873088	49873111	19	+	27260156	EWS502	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.11375066122702582	[122]	[70,88,158,263]	2	hSpCas9	negative selection	6255179
49869942	49869965	19	+	27260156	EWS502	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.10648062614943665	[89]	[62,61,125,108]	-2	hSpCas9	negative selection	6319459
49871687	49871710	19	+	27260156	EWS502	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.6949655322109748	[165]	[235,449,226,217]	9	hSpCas9	negative selection	6319460
49871811	49871834	19	-	27260156	EWS502	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5235633935746087	[321]	[163,264,315,209]	-7	hSpCas9	negative selection	6319461
49870018	49870041	19	+	27260156	EW8	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.648493902791372	[166]	[264,194,144,259]	9	hSpCas9	negative selection	6376428
49873115	49873138	19	+	27260156	EW8	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.2663169802616925	[237]	[191,201,312,201]	5	hSpCas9	negative selection	6376429
49873088	49873111	19	+	27260156	EW8	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.46678938225586153	[122]	[27,71,67,115]	-7	hSpCas9	negative selection	6376430
49869942	49869965	19	+	27260156	EW8	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.4704105522155073	[89]	[108,66,27,16]	-7	hSpCas9	negative selection	6440710
49871687	49871710	19	+	27260156	EW8	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.5852188934185378	[165]	[206,229,234,129]	9	hSpCas9	negative selection	6440711
49871811	49871834	19	-	27260156	EW8	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.6241975557694	[321]	[212,143,231,81]	-8	hSpCas9	negative selection	6440712
49870018	49870041	19	+	27260156	CORL105	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.20196721593608524	[166]	[298,208,233,161]	4	hSpCas9	negative selection	6497679
49873115	49873138	19	+	27260156	CORL105	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.73933505964558	[237]	[537,497,560,280]	9	hSpCas9	negative selection	6497680
49873088	49873111	19	+	27260156	CORL105	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.1598155978409559	[122]	[168,64,190,102]	-3	hSpCas9	negative selection	6497681
49869942	49869965	19	+	27260156	CORL105	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.3340836771757991	[89]	[64,153,67,42]	-6	hSpCas9	negative selection	6561961
49871687	49871710	19	+	27260156	CORL105	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.6086705628960061	[165]	[300,250,251,374]	9	hSpCas9	negative selection	6561962
49871811	49871834	19	-	27260156	CORL105	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5315419539288031	[321]	[307,287,282,168]	-7	hSpCas9	negative selection	6561963
49870018	49870041	19	+	27260156	HS294T	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	1.1132609509583893	[166]	[131,117,108,212]	9	hSpCas9	negative selection	6618930
49873115	49873138	19	+	27260156	HS294T	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.899201632719019	[237]	[118,121,133,346]	9	hSpCas9	negative selection	6618931
49873088	49873111	19	+	27260156	HS294T	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.7341413115090709	[122]	[59,35,86,147]	8	hSpCas9	negative selection	6618932
49869942	49869965	19	+	27260156	HS294T	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-1.0380577712569252	[89]	[15,11,17,22]	-9	hSpCas9	negative selection	6683212
49871687	49871710	19	+	27260156	HS294T	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	1.14947764756316	[165]	[59,84,76,399]	9	hSpCas9	negative selection	6683213
49871811	49871834	19	-	27260156	HS294T	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.09127720130931394	[321]	[163,87,76,137]	-1	hSpCas9	negative selection	6683214
49870018	49870041	19	+	27260156	HCC44	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.708771093809489	[166]	[344,235,406,275]	9	hSpCas9	negative selection	6740181
49873115	49873138	19	+	27260156	HCC44	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.48834967873740825	[237]	[514,371,208,394]	7	hSpCas9	negative selection	6740182
49873088	49873111	19	+	27260156	HCC44	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.6580406540865709	[122]	[225,115,389,189]	9	hSpCas9	negative selection	6740183
49869942	49869965	19	+	27260156	HCC44	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.16218425809199877	[89]	[85,160,46,138]	2	hSpCas9	negative selection	6804463
49871687	49871710	19	+	27260156	HCC44	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.9757645958086112	[165]	[403,337,426,323]	9	hSpCas9	negative selection	6804464
49871811	49871834	19	-	27260156	HCC44	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	0.3264730774898349	[321]	[385,343,810,355]	5	hSpCas9	negative selection	6804465
49870018	49870041	19	+	27260156	G402	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.8146468905668215	[166]	[467,274,336,362]	8	hSpCas9	negative selection	6861432
49873115	49873138	19	+	27260156	G402	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.6668330045723696	[237]	[712,388,298,472]	8	hSpCas9	negative selection	6861433
49873088	49873111	19	+	27260156	G402	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.2681802617087623	[122]	[16,512,71,118]	3	hSpCas9	negative selection	6861434
49869942	49869965	19	+	27260156	G402	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.4202709640610822	[89]	[229,122,100,143]	5	hSpCas9	negative selection	6925714
49871687	49871710	19	+	27260156	G402	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.9254446679563464	[165]	[464,544,306,247]	9	hSpCas9	negative selection	6925715
49871811	49871834	19	-	27260156	G402	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.7460223620832314	[321]	[280,353,146,170]	-7	hSpCas9	negative selection	6925716
49870018	49870041	19	+	27260156	L33	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.7434589379622476	[166]	[281,116,150,309]	9	hSpCas9	negative selection	6982683
49873115	49873138	19	+	27260156	L33	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.2969615401702903	[237]	[269,135,221,215]	6	hSpCas9	negative selection	6982684
49873088	49873111	19	+	27260156	L33	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.2882709437425881	[122]	[195,58,71,144]	6	hSpCas9	negative selection	6982685
49869942	49869965	19	+	27260156	L33	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.09953925458368129	[89]	[60,45,45,89]	-2	hSpCas9	negative selection	7046965
49871687	49871710	19	+	27260156	L33	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.2236262854233555	[165]	[171,105,113,163]	5	hSpCas9	negative selection	7046966
49871811	49871834	19	-	27260156	L33	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	0.05708560783531097	[321]	[341,130,258,266]	1	hSpCas9	negative selection	7046967
49870018	49870041	19	+	27260156	K562	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.48189965515495725	[166]	[211,209,211,194]	6	hSpCas9	negative selection	7103934
49873115	49873138	19	+	27260156	K562	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	1.9548193586453961	[237]	[631,1010,1224,442]	9	hSpCas9	negative selection	7103935
49873088	49873111	19	+	27260156	K562	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.08143975571399209	[122]	[243,99,75,57]	1	hSpCas9	negative selection	7103936
49869942	49869965	19	+	27260156	K562	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.9328504499145118	[89]	[34,66,395,102]	9	hSpCas9	negative selection	7168216
49871687	49871710	19	+	27260156	K562	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.587789775997428	[165]	[191,450,158,105]	7	hSpCas9	negative selection	7168217
49871811	49871834	19	-	27260156	K562	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.9172565921794953	[321]	[117,62,92,304]	-8	hSpCas9	negative selection	7168218
49870018	49870041	19	+	27260156	HT29	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.361381714344053	[166]	[233,301,310,202]	7	hSpCas9	negative selection	7225185
49873115	49873138	19	+	27260156	HT29	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.31872077186236136	[237]	[487,331,266,360]	6	hSpCas9	negative selection	7225186
49873088	49873111	19	+	27260156	HT29	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.2940483893248311	[122]	[127,67,184,103]	-5	hSpCas9	negative selection	7225187
49869942	49869965	19	+	27260156	HT29	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.5400863712791657	[89]	[53,36,52,142]	-7	hSpCas9	negative selection	7289467
49871687	49871710	19	+	27260156	HT29	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.4059138411704173	[165]	[284,236,211,324]	7	hSpCas9	negative selection	7289468
49871811	49871834	19	-	27260156	HT29	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.6820445989098309	[321]	[326,201,222,226]	-8	hSpCas9	negative selection	7289469
49870018	49870041	19	+	27260156	MHHES1	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5492645065945663	[166]	[253,369,327,173]	8	hSpCas9	negative selection	7346436
49873115	49873138	19	+	27260156	MHHES1	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5551972885629682	[237]	[451,581,350,242]	8	hSpCas9	negative selection	7346437
49873088	49873111	19	+	27260156	MHHES1	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.41454277034958054	[122]	[132,153,78,64]	-7	hSpCas9	negative selection	7346438
49869942	49869965	19	+	27260156	MHHES1	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.4779928722958404	[89]	[78,51,108,52]	-7	hSpCas9	negative selection	7410718
49871687	49871710	19	+	27260156	MHHES1	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.7887089644416513	[165]	[380,249,243,391]	9	hSpCas9	negative selection	7410719
49871811	49871834	19	-	27260156	MHHES1	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.4130989109566293	[321]	[199,446,240,216]	-6	hSpCas9	negative selection	7410720
49870018	49870041	19	+	27260156	MEWO	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.6283021597620446	[166]	[209,314,192]	9	hSpCas9	negative selection	7467687
49873115	49873138	19	+	27260156	MEWO	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.40662706346334987	[237]	[214,270,383]	8	hSpCas9	negative selection	7467688
49873088	49873111	19	+	27260156	MEWO	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.04251859794293411	[122]	[120,104,110]	-1	hSpCas9	negative selection	7467689
49869942	49869965	19	+	27260156	MEWO	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.013587947707595305	[89]	[146,81,37]	0	hSpCas9	negative selection	7531969
49871687	49871710	19	+	27260156	MEWO	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.7820069984727358	[165]	[312,263,232]	9	hSpCas9	negative selection	7531970
49871811	49871834	19	-	27260156	MEWO	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.41837613881855895	[321]	[310,179,201]	-7	hSpCas9	negative selection	7531971
49870018	49870041	19	+	27260156	LNCAPCLONEFGC	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5062904408416614	[166]	[180,178,245,260]	7	hSpCas9	negative selection	7588938
49873115	49873138	19	+	27260156	LNCAPCLONEFGC	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5506055443063325	[237]	[390,228,354,297]	8	hSpCas9	negative selection	7588939
49873088	49873111	19	+	27260156	LNCAPCLONEFGC	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.14354748535540018	[122]	[123,57,135,92]	-2	hSpCas9	negative selection	7588940
49869942	49869965	19	+	27260156	LNCAPCLONEFGC	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.193385843098139	[89]	[71,51,81,81]	-3	hSpCas9	negative selection	7653220
49871687	49871710	19	+	27260156	LNCAPCLONEFGC	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.9576356757942986	[165]	[199,328,417,238]	9	hSpCas9	negative selection	7653221
49871811	49871834	19	-	27260156	LNCAPCLONEFGC	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.9836626563412616	[321]	[190,87,133,177]	-8	hSpCas9	negative selection	7653222
49870018	49870041	19	+	27260156	PANC0327	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.47832623698825594	[166]	[166,216,205,231]	7	hSpCas9	negative selection	7710189
49873115	49873138	19	+	27260156	PANC0327	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.31720249729398264	[237]	[213,203,223,414]	5	hSpCas9	negative selection	7710190
49873088	49873111	19	+	27260156	PANC0327	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.346344137106541	[122]	[90,63,94,96]	-5	hSpCas9	negative selection	7710191
49869942	49869965	19	+	27260156	PANC0327	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.3131912863079669	[89]	[135,139,54,63]	4	hSpCas9	negative selection	7774471
49871687	49871710	19	+	27260156	PANC0327	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.6664917261445052	[165]	[321,205,238,179]	8	hSpCas9	negative selection	7774472
49871811	49871834	19	-	27260156	PANC0327	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.7594803148725482	[321]	[207,237,97,125]	-8	hSpCas9	negative selection	7774473
49870018	49870041	19	+	27260156	NCIH2009	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.6803112675187102	[166]	[541,389,221]	8	hSpCas9	negative selection	7831440
49873115	49873138	19	+	27260156	NCIH2009	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.7082576998676965	[237]	[664,542,444]	8	hSpCas9	negative selection	7831441
49873088	49873111	19	+	27260156	NCIH2009	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.5785981083995295	[122]	[251,287,227]	7	hSpCas9	negative selection	7831442
49869942	49869965	19	+	27260156	NCIH2009	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.018579221638733046	[89]	[227,60,113]	0	hSpCas9	negative selection	7895722
49871687	49871710	19	+	27260156	NCIH2009	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.07331679900675603	[165]	[282,152,304]	1	hSpCas9	negative selection	7895723
49871811	49871834	19	-	27260156	NCIH2009	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.1841919367162923	[321]	[413,493,280]	-3	hSpCas9	negative selection	7895724
49870018	49870041	19	+	27260156	NCIH1373	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.9449610580991753	[166]	[454,145,245,170]	8	hSpCas9	negative selection	7952691
49873115	49873138	19	+	27260156	NCIH1373	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5762467040556056	[237]	[500,337,348,111]	5	hSpCas9	negative selection	7952692
49873088	49873111	19	+	27260156	NCIH1373	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.45443165584693235	[122]	[344,218,52,41]	4	hSpCas9	negative selection	7952693
49869942	49869965	19	+	27260156	NCIH1373	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.515458290915304	[89]	[117,110,37,3]	-5	hSpCas9	negative selection	8016973
49871687	49871710	19	+	27260156	NCIH1373	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.39793041919275285	[165]	[280,150,317,63]	4	hSpCas9	negative selection	8016974
49871811	49871834	19	-	27260156	NCIH1373	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.6089660072444867	[321]	[187,89,445,58]	-6	hSpCas9	negative selection	8016975
49870018	49870041	19	+	27260156	PATU8902	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	1.524490367095209	[166]	[943,593,359,873]	9	hSpCas9	negative selection	8073942
49873115	49873138	19	+	27260156	PATU8902	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	1.082269787477382	[237]	[329,910,850,672]	9	hSpCas9	negative selection	8073943
49873088	49873111	19	+	27260156	PATU8902	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.6399082081780929	[122]	[185,205,353,301]	6	hSpCas9	negative selection	8073944
49869942	49869965	19	+	27260156	PATU8902	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.26437198598757483	[89]	[76,352,20,189]	2	hSpCas9	negative selection	8138224
49871687	49871710	19	+	27260156	PATU8902	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	1.1086494154132749	[165]	[867,429,277,461]	9	hSpCas9	negative selection	8138225
49871811	49871834	19	-	27260156	PATU8902	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.14955144474111193	[321]	[530,457,318,315]	-1	hSpCas9	negative selection	8138226
49870018	49870041	19	+	27260156	PANC1	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.4788724979284982	[166]	[207,265,160,177]	7	hSpCas9	negative selection	8195193
49873115	49873138	19	+	27260156	PANC1	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.02777895079806303	[237]	[177,268,213,185]	0	hSpCas9	negative selection	8195194
49873088	49873111	19	+	27260156	PANC1	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.2906903210198797	[122]	[120,98,126,156]	5	hSpCas9	negative selection	8195195
49869942	49869965	19	+	27260156	PANC1	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.18628228603038366	[89]	[133,86,34,91]	3	hSpCas9	negative selection	8259475
49871687	49871710	19	+	27260156	PANC1	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.5355699273885636	[165]	[209,292,214,134]	8	hSpCas9	negative selection	8259476
49871811	49871834	19	-	27260156	PANC1	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5941394550155115	[321]	[234,130,156,192]	-7	hSpCas9	negative selection	8259477
49870018	49870041	19	+	27260156	PANC0813	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.9402829860555222	[166]	[349,464,237,444]	9	hSpCas9	negative selection	8316444
49873115	49873138	19	+	27260156	PANC0813	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5382205758194107	[237]	[405,333,483,399]	8	hSpCas9	negative selection	8316445
49873088	49873111	19	+	27260156	PANC0813	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.014528674046899726	[122]	[174,153,178,81]	0	hSpCas9	negative selection	8316446
49869942	49869965	19	+	27260156	PANC0813	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.29619821177858974	[89]	[158,24,80,85]	-5	hSpCas9	negative selection	8380726
49871687	49871710	19	+	27260156	PANC0813	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.5931085941087694	[165]	[341,263,323,252]	8	hSpCas9	negative selection	8380727
49871811	49871834	19	-	27260156	PANC0813	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.2436218399860478	[321]	[284,206,464,317]	-4	hSpCas9	negative selection	8380728
49870018	49870041	19	+	27260156	RDES	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.7180201142784235	[166]	[220,341,356,360]	9	hSpCas9	negative selection	8437695
49873115	49873138	19	+	27260156	RDES	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.4585671520273711	[237]	[244,394,411,486]	7	hSpCas9	negative selection	8437696
49873088	49873111	19	+	27260156	RDES	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.36866664926787074	[122]	[113,44,176,105]	-6	hSpCas9	negative selection	8437697
49869942	49869965	19	+	27260156	RDES	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.325977567514955	[89]	[86,181,96,155]	5	hSpCas9	negative selection	8501977
49871687	49871710	19	+	27260156	RDES	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.8531531551191899	[165]	[218,202,450,578]	9	hSpCas9	negative selection	8501978
49871811	49871834	19	-	27260156	RDES	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.7358952360867466	[321]	[216,223,164,283]	-8	hSpCas9	negative selection	8501979
49870018	49870041	19	+	27260156	PC3	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.08885300154044717	[166]	[108,154,399,143]	2	hSpCas9	negative selection	8558946
49873115	49873138	19	+	27260156	PC3	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.06784857720129112	[237]	[221,211,328,242]	1	hSpCas9	negative selection	8558947
49873088	49873111	19	+	27260156	PC3	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.19531893806641265	[122]	[79,199,162,136]	4	hSpCas9	negative selection	8558948
49869942	49869965	19	+	27260156	PC3	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.5027290406503504	[89]	[88,60,182,207]	8	hSpCas9	negative selection	8623228
49871687	49871710	19	+	27260156	PC3	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.5010391613582525	[165]	[109,161,542,285]	8	hSpCas9	negative selection	8623229
49871811	49871834	19	-	27260156	PC3	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.7263203642783171	[321]	[123,226,344,145]	-9	hSpCas9	negative selection	8623230
49870018	49870041	19	+	27260156	PATU8988T	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.465873505152522	[166]	[328,205,251,91]	7	hSpCas9	negative selection	8680197
49873115	49873138	19	+	27260156	PATU8988T	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.3903296545610446	[237]	[333,386,223,266]	6	hSpCas9	negative selection	8680198
49873088	49873111	19	+	27260156	PATU8988T	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.19432685170594577	[122]	[179,111,74,178]	3	hSpCas9	negative selection	8680199
49869942	49869965	19	+	27260156	PATU8988T	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.038172981309455345	[89]	[60,66,60,153]	0	hSpCas9	negative selection	8744479
49871687	49871710	19	+	27260156	PATU8988T	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.7403786057493169	[165]	[220,306,272,274]	9	hSpCas9	negative selection	8744480
49871811	49871834	19	-	27260156	PATU8988T	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.1770511535017839	[321]	[259,303,260,278]	-3	hSpCas9	negative selection	8744481
49870018	49870041	19	+	27260156	T47D	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.6123623832191333	[166]	[374,338,261,207]	9	hSpCas9	negative selection	8801448
49873115	49873138	19	+	27260156	T47D	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.3488789110212449	[237]	[358,323,327,405]	7	hSpCas9	negative selection	8801449
49873088	49873111	19	+	27260156	T47D	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.13639525661808838	[122]	[140,157,83,136]	-3	hSpCas9	negative selection	8801450
49869942	49869965	19	+	27260156	T47D	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.18220208442994323	[89]	[155,72,34,108]	-4	hSpCas9	negative selection	8865730
49871687	49871710	19	+	27260156	T47D	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.486656535444528	[165]	[283,263,296,237]	8	hSpCas9	negative selection	8865731
49871811	49871834	19	-	27260156	T47D	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5570996050583519	[321]	[275,269,260,209]	-8	hSpCas9	negative selection	8865732
49870018	49870041	19	+	27260156	SU8686	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5224447761461766	[166]	[257,267,174,240]	8	hSpCas9	negative selection	8922699
49873115	49873138	19	+	27260156	SU8686	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5367791923262133	[237]	[350,272,463,279]	8	hSpCas9	negative selection	8922700
49873088	49873111	19	+	27260156	SU8686	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.1819258472922669	[122]	[108,97,112,259]	3	hSpCas9	negative selection	8922701
49869942	49869965	19	+	27260156	SU8686	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.6006524406879112	[89]	[38,83,74,31]	-7	hSpCas9	negative selection	8986981
49871687	49871710	19	+	27260156	SU8686	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.2650749445327587	[165]	[148,181,265,202]	4	hSpCas9	negative selection	8986982
49871811	49871834	19	-	27260156	SU8686	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5878558816448178	[321]	[175,234,173,272]	-7	hSpCas9	negative selection	8986983
49870018	49870041	19	+	27260156	SKES1	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5940661645209543	[166]	[336,216,283,180]	9	hSpCas9	negative selection	9043950
49873115	49873138	19	+	27260156	SKES1	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.38642881047267486	[237]	[341,322,263,314]	7	hSpCas9	negative selection	9043951
49873088	49873111	19	+	27260156	SKES1	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.3443264414040126	[122]	[137,95,159,210]	7	hSpCas9	negative selection	9043952
49869942	49869965	19	+	27260156	SKES1	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	-0.4184181139365766	[89]	[70,68,73,55]	-7	hSpCas9	negative selection	9108232
49871687	49871710	19	+	27260156	SKES1	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.42916626582827777	[165]	[292,239,153,215]	8	hSpCas9	negative selection	9108233
49871811	49871834	19	-	27260156	SKES1	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.49380113623678	[321]	[149,226,301,219]	-8	hSpCas9	negative selection	9108234
49870018	49870041	19	+	27260156	TOV112D	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.7615740395973115	[166]	[351,316,239,239]	9	hSpCas9	negative selection	9165201
49873115	49873138	19	+	27260156	TOV112D	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	-0.057283239264964925	[237]	[243,299,172,217]	-1	hSpCas9	negative selection	9165202
49873088	49873111	19	+	27260156	TOV112D	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.0300792285367828	[122]	[149,245,64,74]	0	hSpCas9	negative selection	9165203
49869942	49869965	19	+	27260156	TOV112D	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.5236463324623188	[89]	[87,91,109,212]	8	hSpCas9	negative selection	9229483
49871687	49871710	19	+	27260156	TOV112D	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.7018969693275248	[165]	[329,473,118,214]	9	hSpCas9	negative selection	9229484
49871811	49871834	19	-	27260156	TOV112D	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.5071097190610838	[321]	[193,271,199,248]	-7	hSpCas9	negative selection	9229485
49870018	49870041	19	+	27260156	TC71	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.5213181862498163	[166]	[238,227,258,304]	9	hSpCas9	negative selection	9286452
49873115	49873138	19	+	27260156	TC71	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.04517687547794269	[237]	[231,239,205,384]	1	hSpCas9	negative selection	9286453
49873088	49873111	19	+	27260156	TC71	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	-0.2553135396563748	[122]	[78,120,129,111]	-6	hSpCas9	negative selection	9286454
49869942	49869965	19	+	27260156	TC71	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.13821339712806147	[89]	[124,110,112,72]	3	hSpCas9	negative selection	9350734
49871687	49871710	19	+	27260156	TC71	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.7911571811546758	[165]	[305,309,284,332]	9	hSpCas9	negative selection	9350735
49871811	49871834	19	-	27260156	TC71	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.21300249140595906	[321]	[326,251,282,330]	-5	hSpCas9	negative selection	9350736
49870018	49870041	19	+	27260156	TC32	viability	CGCGCATGCTCGCCGCGATGCGG	AKT1S1	ENSG00000204673	0.442562037444707	[166]	[184,144,275,278]	7	hSpCas9	negative selection	9407703
49873115	49873138	19	+	27260156	TC32	viability	AACGGCGCGCTGCCTCCGCCAGG	AKT1S1	ENSG00000204673	0.5791297564746631	[237]	[270,282,374,426]	8	hSpCas9	negative selection	9407704
49873088	49873111	19	+	27260156	TC32	viability	TGTGGGCCAGTGCGATGTCGTGG	AKT1S1	ENSG00000204673	0.04370788273708737	[122]	[116,90,156,121]	0	hSpCas9	negative selection	9407705
49869942	49869965	19	+	27260156	TC32	viability	AAGTCGCTGGTGTTAAGCCGCGG	AKT1S1	ENSG00000204673	0.4031621744780187	[89]	[134,100,64,132]	7	hSpCas9	negative selection	9471985
49871687	49871710	19	+	27260156	TC32	viability	CGGCGGGGGTCTCCTCGCTCAGG	AKT1S1	ENSG00000204673	0.9718096024239473	[165]	[308,326,248,298]	9	hSpCas9	negative selection	9471986
49871811	49871834	19	-	27260156	TC32	viability	TCAGACCCCGAGAGTACAGATGG	AKT1S1	ENSG00000204673	-0.8388936723385216	[321]	[184,125,173,197]	-9	hSpCas9	negative selection	9471987
49869948	49869971	19	+	27869803	HPAFII	viability after 27 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.3761772035201612	[337]	[162,286,NaN]	3	hSpCas9	negative selection	9569271
49870038	49870061	19	+	27869803	HPAFII	viability after 27 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.4250616361185737	[614]	[254,228,NaN]	-3	hSpCas9	negative selection	9569272
49872984	49873007	19	+	27869803	HPAFII	viability after 27 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.3431735843338163	[353]	[186,276,NaN]	2	hSpCas9	negative selection	9569273
49873133	49873156	19	-	27869803	HPAFII	viability after 27 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.42542485208345615	[316]	[267,186,NaN]	3	hSpCas9	negative selection	9569274
49876599	49876622	19	+	27869803	HPAFII	viability after 27 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.7774374689471506	[641]	[685,488,NaN]	6	hSpCas9	negative selection	9569275
49876627	49876650	19	-	27869803	HPAFII	viability after 27 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.440330891598644	[359]	[222,284,NaN]	3	hSpCas9	negative selection	9569276
49869948	49869971	19	+	27869803	HPAFII	viability after 15 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	-0.006719871240289332	[337]	[228,443,NaN]	0	hSpCas9	negative selection	9651720
49870038	49870061	19	+	27869803	HPAFII	viability after 15 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.5034597022790094	[614]	[456,471,NaN]	-5	hSpCas9	negative selection	9651721
49872984	49873007	19	+	27869803	HPAFII	viability after 15 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.10857544957324639	[353]	[416,312,NaN]	-1	hSpCas9	negative selection	9651722
49873133	49873156	19	-	27869803	HPAFII	viability after 15 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-0.3443991782190065	[316]	[329,229,NaN]	-4	hSpCas9	negative selection	9651723
49876599	49876622	19	+	27869803	HPAFII	viability after 15 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.49763063171347555	[641]	[1041,931,NaN]	6	hSpCas9	negative selection	9651724
49876627	49876650	19	-	27869803	HPAFII	viability after 15 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	-0.270613315911944	[359]	[456,235,NaN]	-3	hSpCas9	negative selection	9651725
49869948	49869971	19	+	27869803	ASPC1	viability after 36 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.9905159984378278	[684]	[675,240,514]	8	hSpCas9	negative selection	9734169
49870038	49870061	19	+	27869803	ASPC1	viability after 36 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	0.16981898814421914	[1571]	[354,674,748]	1	hSpCas9	negative selection	9734170
49872984	49873007	19	+	27869803	ASPC1	viability after 36 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	1.084277071907004	[1113]	[2315,217,250]	8	hSpCas9	negative selection	9734171
49873133	49873156	19	-	27869803	ASPC1	viability after 36 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.0156252110066456	[781]	[252,551,69]	0	hSpCas9	negative selection	9734172
49876599	49876622	19	+	27869803	ASPC1	viability after 36 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	-0.11149817024882736	[1519]	[389,422,610]	-1	hSpCas9	negative selection	9734173
49876627	49876650	19	-	27869803	ASPC1	viability after 36 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.2124955947006891	[695]	[271,471,133]	2	hSpCas9	negative selection	9734174
49869948	49869971	19	+	27869803	PATU8988S	viability after 35 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.8231815356280071	[711]	[665,347,NaN]	8	hSpCas9	negative selection	9816618
49870038	49870061	19	+	27869803	PATU8988S	viability after 35 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.5212054294359371	[1189]	[312,354,NaN]	-5	hSpCas9	negative selection	9816619
49872984	49873007	19	+	27869803	PATU8988S	viability after 35 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	-0.05789764119870788	[967]	[385,362,NaN]	0	hSpCas9	negative selection	9816620
49873133	49873156	19	-	27869803	PATU8988S	viability after 35 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-1.0384706712765892	[567]	[54,167,NaN]	-7	hSpCas9	negative selection	9816621
49876599	49876622	19	+	27869803	PATU8988S	viability after 35 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	-0.7524388448358786	[1331]	[293,342,NaN]	-6	hSpCas9	negative selection	9816622
49876627	49876650	19	-	27869803	PATU8988S	viability after 35 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.07863314033869645	[682]	[284,295,NaN]	0	hSpCas9	negative selection	9816623
49869948	49869971	19	+	27869803	PATU8988S	viability after 31 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.2821910932928826	[711]	[346,342,NaN]	3	hSpCas9	negative selection	9899067
49870038	49870061	19	+	27869803	PATU8988S	viability after 31 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.3181864548381924	[1189]	[329,444,NaN]	-4	hSpCas9	negative selection	9899068
49872984	49873007	19	+	27869803	PATU8988S	viability after 31 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.05743445054231244	[967]	[303,525,NaN]	0	hSpCas9	negative selection	9899069
49873133	49873156	19	-	27869803	PATU8988S	viability after 31 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	-1.3548059579568348	[567]	[55,129,NaN]	-8	hSpCas9	negative selection	9899070
49876599	49876622	19	+	27869803	PATU8988S	viability after 31 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	-0.7036111384711019	[1331]	[370,268,NaN]	-6	hSpCas9	negative selection	9899071
49876627	49876650	19	-	27869803	PATU8988S	viability after 31 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.42310533565060426	[682]	[358,372,NaN]	5	hSpCas9	negative selection	9899072
49869948	49869971	19	+	27869803	HPAFII	viability after 35 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.26369025862445067	[337]	[116,304,NaN]	1	hSpCas9	negative selection	9981516
49870038	49870061	19	+	27869803	HPAFII	viability after 35 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.5225119044931082	[614]	[172,265,NaN]	-3	hSpCas9	negative selection	9981517
49872984	49873007	19	+	27869803	HPAFII	viability after 35 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.3068939477233492	[353]	[73,387,NaN]	2	hSpCas9	negative selection	9981518
49873133	49873156	19	-	27869803	HPAFII	viability after 35 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.2099007361603722	[316]	[234,129,NaN]	1	hSpCas9	negative selection	9981519
49876599	49876622	19	+	27869803	HPAFII	viability after 35 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.702642837769641	[641]	[424,645,NaN]	4	hSpCas9	negative selection	9981520
49876627	49876650	19	-	27869803	HPAFII	viability after 35 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	1.0757472981567835	[359]	[322,452,NaN]	7	hSpCas9	negative selection	9981521
49869948	49869971	19	+	27869803	HPAFII	viability after 31 days	CTGGTGTTAAGCCGCGGCCGTGG	AKT1S1	ENSG00000204673	0.258767847050195	[337]	[158,300,NaN]	1	hSpCas9	negative selection	10063965
49870038	49870061	19	+	27869803	HPAFII	viability after 31 days	CGGTCCAGGTCGGGCGAAGAGGG	AKT1S1	ENSG00000204673	-0.6652051906508061	[614]	[153,286,NaN]	-4	hSpCas9	negative selection	10063966
49872984	49873007	19	+	27869803	HPAFII	viability after 31 days	CTCGTTGTCCTCTCTGGCCAGGG	AKT1S1	ENSG00000204673	0.856129482635557	[353]	[127,611,NaN]	6	hSpCas9	negative selection	10063967
49873133	49873156	19	-	27869803	HPAFII	viability after 31 days	TGCCCATGGTCGAGGAGCCCTGG	AKT1S1	ENSG00000204673	0.21512994345548353	[316]	[217,193,NaN]	1	hSpCas9	negative selection	10063968
49876599	49876622	19	+	27869803	HPAFII	viability after 31 days	TCACGTGCCCGTAGCCAGCATGG	AKT1S1	ENSG00000204673	0.5685250648303937	[641]	[429,647,NaN]	4	hSpCas9	negative selection	10063969
49876627	49876650	19	-	27869803	HPAFII	viability after 31 days	TTTGAGGGCGGTGACGGCGCCGG	AKT1S1	ENSG00000204673	0.7933179501548187	[359]	[330,370,NaN]	6	hSpCas9	negative selection	10063970
49873253	49873276	19	-	28162770	P31FUJ	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-2.6330859370031954	[226]	[42]	-9	hSpCas9	negative selection	10109107
49872994	49873017	19	+	28162770	P31FUJ	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.2868688360550584	[112]	[161]	3	hSpCas9	negative selection	10109108
49873127	49873150	19	-	28162770	P31FUJ	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.3443105196313694	[120]	[55]	-7	hSpCas9	negative selection	10109109
49873070	49873093	19	+	28162770	P31FUJ	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-1.232802204414379	[59]	[29]	-7	hSpCas9	negative selection	10109110
49873024	49873047	19	+	28162770	P31FUJ	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-1.9800361340344121	[46]	[13]	-8	hSpCas9	negative selection	10109111
49872980	49873003	19	-	28162770	P31FUJ	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.4677072370643753	[192]	[163]	-4	hSpCas9	negative selection	10109112
49872930	49872953	19	+	28162770	P31FUJ	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.09553672951258552	[550]	[605]	-1	hSpCas9	negative selection	10109113
49871604	49871627	19	+	28162770	P31FUJ	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.14396527793674793	[190]	[247]	1	hSpCas9	negative selection	10109114
49873196	49873219	19	-	28162770	P31FUJ	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.9287960175242789	[161]	[49]	-8	hSpCas9	negative selection	10109115
49873091	49873114	19	+	28162770	P31FUJ	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.3703057281643135	[318]	[289]	-3	hSpCas9	negative selection	10109116
49873253	49873276	19	-	28162770	TF1	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10278473
49872994	49873017	19	+	28162770	TF1	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10278474
49873127	49873150	19	-	28162770	TF1	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[16]	1	hSpCas9	negative selection	10278475
49873070	49873093	19	+	28162770	TF1	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10278476
49873024	49873047	19	+	28162770	TF1	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10278477
49872980	49873003	19	-	28162770	TF1	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10278478
49872930	49872953	19	+	28162770	TF1	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[200]	1	hSpCas9	negative selection	10278479
49871604	49871627	19	+	28162770	TF1	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10278480
49873196	49873219	19	-	28162770	TF1	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10278481
49873091	49873114	19	+	28162770	TF1	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10278482
49873253	49873276	19	-	28162770	SKM1	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.3245020385511888	[84]	[14]	-9	hSpCas9	negative selection	10447839
49872994	49873017	19	+	28162770	SKM1	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	1.1537507557313171	[14]	[58]	9	hSpCas9	negative selection	10447840
49873127	49873150	19	-	28162770	SKM1	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-0.15215029971433625	[43]	[69]	-1	hSpCas9	negative selection	10447841
49873070	49873093	19	+	28162770	SKM1	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-0.2370391973008492	[15]	[23]	-2	hSpCas9	negative selection	10447842
49873024	49873047	19	+	28162770	SKM1	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-0.04439411935845339	[20]	[35]	0	hSpCas9	negative selection	10447843
49872980	49873003	19	-	28162770	SKM1	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.29998882635660473	[50]	[110]	3	hSpCas9	negative selection	10447844
49872930	49872953	19	+	28162770	SKM1	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.4662432706090681	[103]	[253]	4	hSpCas9	negative selection	10447845
49871604	49871627	19	+	28162770	SKM1	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.11443317320052807	[57]	[110]	1	hSpCas9	negative selection	10447846
49873196	49873219	19	-	28162770	SKM1	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10447847
49873091	49873114	19	+	28162770	SKM1	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	1.0006523604184812	[66]	[236]	8	hSpCas9	negative selection	10447848
49873253	49873276	19	-	28162770	SKM1	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.3245020385511888	[84]	[14]	-9	hSpCas9	negative selection	10617205
49872994	49873017	19	+	28162770	SKM1	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	1.1537507557313171	[14]	[58]	9	hSpCas9	negative selection	10617206
49873127	49873150	19	-	28162770	SKM1	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-0.15215029971433625	[43]	[69]	-1	hSpCas9	negative selection	10617207
49873070	49873093	19	+	28162770	SKM1	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-0.2370391973008492	[15]	[23]	-2	hSpCas9	negative selection	10617208
49873024	49873047	19	+	28162770	SKM1	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-0.04439411935845339	[20]	[35]	0	hSpCas9	negative selection	10617209
49872980	49873003	19	-	28162770	SKM1	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.29998882635660473	[50]	[110]	3	hSpCas9	negative selection	10617210
49872930	49872953	19	+	28162770	SKM1	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.4662432706090681	[103]	[253]	4	hSpCas9	negative selection	10617211
49871604	49871627	19	+	28162770	SKM1	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.11443317320052807	[57]	[110]	1	hSpCas9	negative selection	10617212
49873196	49873219	19	-	28162770	SKM1	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-0.37454272105078423	[32]	[44]	-3	hSpCas9	negative selection	10617213
49873091	49873114	19	+	28162770	SKM1	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	1.0006523604184812	[66]	[236]	8	hSpCas9	negative selection	10617214
49873253	49873276	19	-	28162770	PL21	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.169094195176399	[309]	[14]	-9	hSpCas9	negative selection	10786571
49872994	49873017	19	+	28162770	PL21	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	2.1741444059563757	[55]	[109]	9	hSpCas9	negative selection	10786572
49873127	49873150	19	-	28162770	PL21	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-0.48212008758675107	[137]	[42]	-3	hSpCas9	negative selection	10786573
49873070	49873093	19	+	28162770	PL21	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-2.424351250418473	[73]	[5]	-9	hSpCas9	negative selection	10786574
49873024	49873047	19	+	28162770	PL21	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-0.25237259020818636	[51]	[18]	-2	hSpCas9	negative selection	10786575
49872980	49873003	19	-	28162770	PL21	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-1.277907682315324	[194]	[34]	-7	hSpCas9	negative selection	10786576
49872930	49872953	19	+	28162770	PL21	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.1061068581657727	[365]	[147]	-1	hSpCas9	negative selection	10786577
49871604	49871627	19	+	28162770	PL21	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	-1.0336575701193769	[126]	[26]	-6	hSpCas9	negative selection	10786578
49873196	49873219	19	-	28162770	PL21	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-2.1547031028707773	[132]	[12]	-8	hSpCas9	negative selection	10786579
49873091	49873114	19	+	28162770	PL21	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.22255145733295892	[251]	[93]	-2	hSpCas9	negative selection	10786580
49873253	49873276	19	-	28162770	P31FUJ	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-2.6330859370031954	[226]	[42]	-9	hSpCas9	negative selection	10955937
49872994	49873017	19	+	28162770	P31FUJ	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.2868688360550584	[112]	[161]	3	hSpCas9	negative selection	10955938
49873127	49873150	19	-	28162770	P31FUJ	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.3443105196313694	[120]	[55]	-7	hSpCas9	negative selection	10955939
49873070	49873093	19	+	28162770	P31FUJ	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-1.232802204414379	[59]	[29]	-7	hSpCas9	negative selection	10955940
49873024	49873047	19	+	28162770	P31FUJ	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-1.9800361340344121	[46]	[13]	-8	hSpCas9	negative selection	10955941
49872980	49873003	19	-	28162770	P31FUJ	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.4677072370643753	[192]	[163]	-4	hSpCas9	negative selection	10955942
49872930	49872953	19	+	28162770	P31FUJ	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.09553672951258552	[550]	[605]	-1	hSpCas9	negative selection	10955943
49871604	49871627	19	+	28162770	P31FUJ	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	0.14396527793674793	[190]	[247]	1	hSpCas9	negative selection	10955944
49873196	49873219	19	-	28162770	P31FUJ	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.9287960175242789	[161]	[49]	-8	hSpCas9	negative selection	10955945
49873091	49873114	19	+	28162770	P31FUJ	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.3703057281643135	[318]	[289]	-3	hSpCas9	negative selection	10955946
49873253	49873276	19	-	28162770	OCIAML5	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.448433834857403	[126]	[20]	-9	hSpCas9	negative selection	11125303
49872994	49873017	19	+	28162770	OCIAML5	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.06220355511011899	[51]	[97]	0	hSpCas9	negative selection	11125304
49873127	49873150	19	-	28162770	OCIAML5	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-3.3315359427378395	[144]	[25]	-9	hSpCas9	negative selection	11125305
49873070	49873093	19	+	28162770	OCIAML5	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	0.5629709284148467	[8]	[23]	5	hSpCas9	negative selection	11125306
49873024	49873047	19	+	28162770	OCIAML5	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-1.7451513669474852	[38]	[20]	-7	hSpCas9	negative selection	11125307
49872980	49873003	19	-	28162770	OCIAML5	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.5306532081421185	[78]	[205]	4	hSpCas9	negative selection	11125308
49872930	49872953	19	+	28162770	OCIAML5	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.1871547389337216	[253]	[521]	1	hSpCas9	negative selection	11125309
49871604	49871627	19	+	28162770	OCIAML5	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	1.4894017104190105	[43]	[222]	9	hSpCas9	negative selection	11125310
49873196	49873219	19	-	28162770	OCIAML5	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	0.18355733886672443	[59]	[122]	1	hSpCas9	negative selection	11125311
49873091	49873114	19	+	28162770	OCIAML5	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.8028230518441479	[143]	[148]	-5	hSpCas9	negative selection	11125312
49873253	49873276	19	-	28162770	EOL1	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-2.5224574563669453	[577]	[52]	-8	hSpCas9	negative selection	11294669
49872994	49873017	19	+	28162770	EOL1	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.9245477715705345	[101]	[101]	7	hSpCas9	negative selection	11294670
49873127	49873150	19	-	28162770	EOL1	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	2.6716732319569623	[282]	[949]	9	hSpCas9	negative selection	11294671
49873070	49873093	19	+	28162770	EOL1	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-1.9580952777913068	[117]	[15]	-8	hSpCas9	negative selection	11294672
49873024	49873047	19	+	28162770	EOL1	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-2.1395825658491807	[91]	[10]	-8	hSpCas9	negative selection	11294673
49872980	49873003	19	-	28162770	EOL1	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.0019900664884443253	[267]	[140]	0	hSpCas9	negative selection	11294674
49872930	49872953	19	+	28162770	EOL1	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.2509276510289815	[452]	[283]	2	hSpCas9	negative selection	11294675
49871604	49871627	19	+	28162770	EOL1	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	-0.24030624032435594	[212]	[94]	-2	hSpCas9	negative selection	11294676
49873196	49873219	19	-	28162770	EOL1	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.0641369152016313	[126]	[31]	-6	hSpCas9	negative selection	11294677
49873091	49873114	19	+	28162770	EOL1	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	0.814670153798161	[299]	[277]	7	hSpCas9	negative selection	11294678
49873253	49873276	19	-	28162770	MOLM13	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-4.586558402477798	[431]	[12]	-9	hSpCas9	negative selection	11464035
49872994	49873017	19	+	28162770	MOLM13	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-1.7591795270013422	[102]	[21]	-7	hSpCas9	negative selection	11464036
49873127	49873150	19	-	28162770	MOLM13	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.2085714736620734	[178]	[55]	-6	hSpCas9	negative selection	11464037
49873070	49873093	19	+	28162770	MOLM13	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-2.068163518695631	[57]	[9]	-7	hSpCas9	negative selection	11464038
49873024	49873047	19	+	28162770	MOLM13	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	0.3329598014584705	[55]	[50]	2	hSpCas9	negative selection	11464039
49872980	49873003	19	-	28162770	MOLM13	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.03390277946474491	[280]	[207]	0	hSpCas9	negative selection	11464040
49872930	49872953	19	+	28162770	MOLM13	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.32548131107732414	[538]	[310]	-2	hSpCas9	negative selection	11464041
49871604	49871627	19	+	28162770	MOLM13	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	-0.4467191272247767	[163]	[86]	-3	hSpCas9	negative selection	11464042
49873196	49873219	19	-	28162770	MOLM13	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-3.3394655405130256	[153]	[10]	-8	hSpCas9	negative selection	11464043
49873091	49873114	19	+	28162770	MOLM13	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-1.0887443961180832	[352]	[119]	-5	hSpCas9	negative selection	11464044
49873253	49873276	19	-	28162770	HEL	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.9074582505601225	[327]	[13]	-9	hSpCas9	negative selection	11633401
49872994	49873017	19	+	28162770	HEL	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.72499295250013	[79]	[30]	-5	hSpCas9	negative selection	11633402
49873127	49873150	19	-	28162770	HEL	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.0471932283223415	[170]	[52]	-6	hSpCas9	negative selection	11633403
49873070	49873093	19	+	28162770	HEL	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-1.0635299649429328	[61]	[18]	-6	hSpCas9	negative selection	11633404
49873024	49873047	19	+	28162770	HEL	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-0.6001176918958069	[70]	[29]	-4	hSpCas9	negative selection	11633405
49872980	49873003	19	-	28162770	HEL	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.5099644289133685	[228]	[102]	-3	hSpCas9	negative selection	11633406
49872930	49872953	19	+	28162770	HEL	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	0.050222936847565736	[382]	[253]	0	hSpCas9	negative selection	11633407
49871604	49871627	19	+	28162770	HEL	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	-0.380847988317259	[184]	[90]	-3	hSpCas9	negative selection	11633408
49873196	49873219	19	-	28162770	HEL	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.1812308039081436	[130]	[36]	-6	hSpCas9	negative selection	11633409
49873091	49873114	19	+	28162770	HEL	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.648492465664089	[278]	[113]	-4	hSpCas9	negative selection	11633410
49873253	49873276	19	-	28162770	MV411	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-3.3552269516718396	[327]	[26]	-9	hSpCas9	negative selection	11802767
49872994	49873017	19	+	28162770	MV411	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.183196803547087	[61]	[45]	-1	hSpCas9	negative selection	11802768
49873127	49873150	19	-	28162770	MV411	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.444440153854893	[125]	[38]	-7	hSpCas9	negative selection	11802769
49873070	49873093	19	+	28162770	MV411	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-5.074490544104587	[79]	[1]	-9	hSpCas9	negative selection	11802770
49873024	49873047	19	+	28162770	MV411	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	0.43647137517279244	[49]	[56]	4	hSpCas9	negative selection	11802771
49872980	49873003	19	-	28162770	MV411	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	-0.9206003411152718	[190]	[84]	-6	hSpCas9	negative selection	11802772
49872930	49872953	19	+	28162770	MV411	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.318541846570808	[301]	[203]	-2	hSpCas9	negative selection	11802773
49871604	49871627	19	+	28162770	MV411	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	-0.26713562204698293	[109]	[76]	-2	hSpCas9	negative selection	11802774
49873196	49873219	19	-	28162770	MV411	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.6204589132098797	[72]	[19]	-7	hSpCas9	negative selection	11802775
49873091	49873114	19	+	28162770	MV411	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.8531663901556304	[192]	[89]	-5	hSpCas9	negative selection	11802776
49873253	49873276	19	-	28162770	MONOMAC1	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-2.012004953227033	[189]	[53]	-8	hSpCas9	negative selection	11972133
49872994	49873017	19	+	28162770	MONOMAC1	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.4121731999082797	[58]	[89]	4	hSpCas9	negative selection	11972134
49873127	49873150	19	-	28162770	MONOMAC1	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.0219501405014624	[123]	[69]	-7	hSpCas9	negative selection	11972135
49873070	49873093	19	+	28162770	MONOMAC1	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-2.071505964975695	[43]	[11]	-9	hSpCas9	negative selection	11972136
49873024	49873047	19	+	28162770	MONOMAC1	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-1.499599617079985	[36]	[14]	-8	hSpCas9	negative selection	11972137
49872980	49873003	19	-	28162770	MONOMAC1	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.433440312913971	[103]	[160]	4	hSpCas9	negative selection	11972138
49872930	49872953	19	+	28162770	MONOMAC1	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.09320103607501362	[200]	[215]	-1	hSpCas9	negative selection	11972139
49871604	49871627	19	+	28162770	MONOMAC1	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	1.5759392828723526	[90]	[310]	9	hSpCas9	negative selection	11972140
49873196	49873219	19	-	28162770	MONOMAC1	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	0.42187298558494024	[55]	[85]	4	hSpCas9	negative selection	11972141
49873091	49873114	19	+	28162770	MONOMAC1	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.14224437421917438	[154]	[160]	-1	hSpCas9	negative selection	11972142
49873253	49873276	19	-	28162770	OCIAML2	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-0.39867998336314625	[43]	[184]	-3	hSpCas9	negative selection	12141499
49872994	49873017	19	+	28162770	OCIAML2	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	-0.14870173035479883	[16]	[84]	-1	hSpCas9	negative selection	12141500
49873127	49873150	19	-	28162770	OCIAML2	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-2.0111982066048637	[23]	[32]	-8	hSpCas9	negative selection	12141501
49873070	49873093	19	+	28162770	OCIAML2	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-0.523097245136297	[6]	[26]	-4	hSpCas9	negative selection	12141502
49873024	49873047	19	+	28162770	OCIAML2	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-0.7336642310759549	[8]	[29]	-5	hSpCas9	negative selection	12141503
49872980	49873003	19	-	28162770	OCIAML2	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	0.2582984498586267	[26]	[178]	2	hSpCas9	negative selection	12141504
49872930	49872953	19	+	28162770	OCIAML2	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.11465424952712144	[66]	[342]	-1	hSpCas9	negative selection	12141505
49871604	49871627	19	+	28162770	OCIAML2	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	-0.5637392296336426	[31]	[119]	-4	hSpCas9	negative selection	12141506
49873196	49873219	19	-	28162770	OCIAML2	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.1976113308357452	[11]	[28]	-7	hSpCas9	negative selection	12141507
49873091	49873114	19	+	28162770	OCIAML2	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	-0.5446304066859382	[44]	[170]	-4	hSpCas9	negative selection	12141508
49873253	49873276	19	-	28162770	OCIAML3	viability	GGAGCTGTGGGAGGCCGTGGTGG	AKT1S1	ENSG00000204673	-2.2389126815016014	[85]	[54]	-8	hSpCas9	negative selection	12310865
49872994	49873017	19	+	28162770	OCIAML3	viability	TCTCTGGCCAGGGTAGGCCGGGG	AKT1S1	ENSG00000204673	0.9394245597569111	[37]	[219]	7	hSpCas9	negative selection	12310866
49873127	49873150	19	-	28162770	OCIAML3	viability	TGGTCGAGGAGCCCTGGCGGAGG	AKT1S1	ENSG00000204673	-1.2970259025670317	[34]	[42]	-7	hSpCas9	negative selection	12310867
49873070	49873093	19	+	28162770	OCIAML3	viability	GAGCAGCAGTGGCAGCCCTGTGG	AKT1S1	ENSG00000204673	-1.594007640324163	[11]	[11]	-8	hSpCas9	negative selection	12310868
49873024	49873047	19	+	28162770	OCIAML3	viability	GGTGTGGGACTGGGTGGCTGTGG	AKT1S1	ENSG00000204673	-2.2314375609394546	[13]	[8]	-8	hSpCas9	negative selection	12310869
49872980	49873003	19	-	28162770	OCIAML3	viability	GGCCAGAGAGGACAACGAGGAGG	AKT1S1	ENSG00000204673	1.5809180421765157	[31]	[288]	9	hSpCas9	negative selection	12310870
49872930	49872953	19	+	28162770	OCIAML3	viability	AATGCCCAGCTGCTCCCCGGAGG	AKT1S1	ENSG00000204673	-0.20573705060810488	[101]	[266]	-2	hSpCas9	negative selection	12310871
49871604	49871627	19	+	28162770	OCIAML3	viability	GACGGGCACAGACACAGGCAGGG	AKT1S1	ENSG00000204673	1.442650830254685	[33]	[278]	9	hSpCas9	negative selection	12310872
49873196	49873219	19	-	28162770	OCIAML3	viability	GGAGCTGGTGCTGCTGACCGCGG	AKT1S1	ENSG00000204673	-1.0534392589614605	[32]	[47]	-6	hSpCas9	negative selection	12310873
49873091	49873114	19	+	28162770	OCIAML3	viability	GGGCCAGTGCGATGTCGTGGAGG	AKT1S1	ENSG00000204673	0.15141953259023916	[67]	[227]	1	hSpCas9	negative selection	12310874