Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 369
• Symbol: ARAF
• Description: A-Raf proto-oncogene, serine/threonine kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/ARAF

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
47563007	47563030	X	-	26472758	Jiyoye	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.3028387216911379	[257]	[239]	2	hSpCas9	negative selection	8826
47565091	47565114	X	-	26472758	Jiyoye	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	-0.34933039905597796	[222]	[131]	-3	hSpCas9	negative selection	8827
47563042	47563065	X	+	26472758	Jiyoye	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.9002153927859902	[26]	[37]	6	hSpCas9	negative selection	8828
47565041	47565064	X	-	26472758	Jiyoye	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.32917286950460034	[94]	[89]	2	hSpCas9	negative selection	8829
47565262	47565285	X	+	26472758	Jiyoye	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.9407479219144337	[55]	[21]	-6	hSpCas9	negative selection	8830
47562960	47562983	X	+	26472758	Jiyoye	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	2.0403930508342505	[48]	[151]	8	hSpCas9	negative selection	8831
47562988	47563011	X	-	26472758	Jiyoye	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.5278568639283368	[148]	[161]	4	hSpCas9	negative selection	8832
47565316	47565339	X	-	26472758	Jiyoye	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	4.7994928042846325	[0]	[20]	9	hSpCas9	negative selection	8833
47563263	47563286	X	+	26472758	Jiyoye	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.3787935801360509	[153]	[150]	3	hSpCas9	negative selection	8834
47563307	47563330	X	+	26472758	Jiyoye	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	-0.8698711147006448	[268]	[110]	-6	hSpCas9	negative selection	8835
47563007	47563030	X	-	26472758	KBM7	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.4857484439201538	[941,746]	[482,613]	5	hSpCas9	negative selection	199944
47565091	47565114	X	-	26472758	KBM7	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	-0.13578314483941867	[1193,978]	[546,386]	-1	hSpCas9	negative selection	199945
47563042	47563065	X	+	26472758	KBM7	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.6544712306889611	[242,126]	[138,127]	7	hSpCas9	negative selection	199946
47565041	47565064	X	-	26472758	KBM7	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.43046617002951615	[457,318]	[301,189]	4	hSpCas9	negative selection	199947
47565262	47565285	X	+	26472758	KBM7	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.779549656000234	[121,62]	[40,9]	-6	hSpCas9	negative selection	199948
47562960	47562983	X	+	26472758	KBM7	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.8990617567760547	[586,303]	[448,317]	8	hSpCas9	negative selection	199949
47562988	47563011	X	-	26472758	KBM7	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.4888672166694804	[594,584]	[402,379]	5	hSpCas9	negative selection	199950
47565316	47565339	X	-	26472758	KBM7	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	0.5043351581540119	[52,39]	[35,25]	5	hSpCas9	negative selection	199951
47563263	47563286	X	+	26472758	KBM7	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	-0.5950465296286758	[605,537]	[180,174]	-5	hSpCas9	negative selection	199952
47563307	47563330	X	+	26472758	KBM7	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	-0.10830678635394075	[959,785]	[439,323]	-1	hSpCas9	negative selection	199953
47563007	47563030	X	-	26472758	Raji	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.2517734447087744	[379]	[104]	2	hSpCas9	negative selection	391062
47565091	47565114	X	-	26472758	Raji	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	-0.7430401085758905	[475]	[65]	-5	hSpCas9	negative selection	391063
47563042	47563065	X	+	26472758	Raji	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.3231122264290365	[61]	[17]	3	hSpCas9	negative selection	391064
47565041	47565064	X	-	26472758	Raji	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	-0.6840298428149832	[179]	[25]	-5	hSpCas9	negative selection	391065
47565262	47565285	X	+	26472758	Raji	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.47935231276055745	[67]	[21]	4	hSpCas9	negative selection	391066
47562960	47562983	X	+	26472758	Raji	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	1.6360778164480103	[121]	[87]	9	hSpCas9	negative selection	391067
47562988	47563011	X	-	26472758	Raji	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.653351904478892	[399]	[145]	6	hSpCas9	negative selection	391068
47565316	47565339	X	-	26472758	Raji	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	1.8594560219300138	[18]	[15]	9	hSpCas9	negative selection	391069
47563263	47563286	X	+	26472758	Raji	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.26492481236007953	[311]	[86]	2	hSpCas9	negative selection	391070
47563307	47563330	X	+	26472758	Raji	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.2702812699219431	[342]	[95]	2	hSpCas9	negative selection	391071
47563007	47563030	X	-	26472758	K562	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.9152590635480086	[749]	[1193]	7	hSpCas9	negative selection	582180
47565091	47565114	X	-	26472758	K562	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.06620873998761989	[894]	[790]	0	hSpCas9	negative selection	582181
47563042	47563065	X	+	26472758	K562	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.5726058130254916	[183]	[230]	4	hSpCas9	negative selection	582182
47565041	47565064	X	-	26472758	K562	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	1.1468634182437731	[259]	[485]	8	hSpCas9	negative selection	582183
47565262	47565285	X	+	26472758	K562	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.1673425046478059	[172]	[327]	8	hSpCas9	negative selection	582184
47562960	47562983	X	+	26472758	K562	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.5909764890625242	[301]	[383]	5	hSpCas9	negative selection	582185
47562988	47563011	X	-	26472758	K562	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.9682089330849198	[659]	[1089]	7	hSpCas9	negative selection	582186
47565316	47565339	X	-	26472758	K562	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	1.4143437291087593	[35]	[80]	9	hSpCas9	negative selection	582187
47563263	47563286	X	+	26472758	K562	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.7945394791753022	[460]	[674]	6	hSpCas9	negative selection	582188
47563307	47563330	X	+	26472758	K562	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.13599626778046126	[662]	[614]	1	hSpCas9	negative selection	582189
47563039	47563062	X	-	26627737	DLD1	viability	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.8396767138081994	[443]	[275,353,136]	7	hSpCas9	negative selection	845739
47563308	47563331	X	+	26627737	DLD1	viability	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.04558577643884398	[726]	[215,250,236]	0	hSpCas9	negative selection	845740
47565061	47565084	X	-	26627737	DLD1	viability	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.6570323579394834	[360]	[127,240,168]	6	hSpCas9	negative selection	845741
47565262	47565285	X	+	26627737	DLD1	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.052150257901312	[186]	[54,226,90]	8	hSpCas9	negative selection	845742
47566722	47566745	X	-	26627737	DLD1	viability	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.4857612152233599	[263]	[262,37,51]	5	hSpCas9	negative selection	845743
47567321	47567344	X	+	26627737	DLD1	viability	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.151810924301142	[444]	[144,175,65]	-2	hSpCas9	negative selection	845744
47563039	47563062	X	-	26627737	GBM cells	viability after 5 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.2945623890563388	[205]	[148,121]	4	hSpCas9	negative selection	928054
47563308	47563331	X	+	26627737	GBM cells	viability after 5 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.17000406578904415	[342]	[159,166]	-3	hSpCas9	negative selection	928055
47565061	47565084	X	-	26627737	GBM cells	viability after 5 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.39981211081836704	[211]	[135,163]	6	hSpCas9	negative selection	928056
47565262	47565285	X	+	26627737	GBM cells	viability after 5 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.36457744723449725	[125]	[71,101]	5	hSpCas9	negative selection	928057
47566722	47566745	X	-	26627737	GBM cells	viability after 5 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.11345843439944858	[236]	[154,119]	1	hSpCas9	negative selection	928058
47567321	47567344	X	+	26627737	GBM cells	viability after 5 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.048057314191494616	[100]	[63,47]	0	hSpCas9	negative selection	928059
47563039	47563062	X	-	26627737	GBM cells	viability after 13 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.09450268958383284	[205]	[91,114]	-1	hSpCas9	negative selection	1010369
47563308	47563331	X	+	26627737	GBM cells	viability after 13 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.3977794859950128	[342]	[175,112]	-5	hSpCas9	negative selection	1010370
47565061	47565084	X	-	26627737	GBM cells	viability after 13 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.06407575278529021	[211]	[138,104]	0	hSpCas9	negative selection	1010371
47565262	47565285	X	+	26627737	GBM cells	viability after 13 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.846820146653157	[125]	[101,139]	8	hSpCas9	negative selection	1010372
47566722	47566745	X	-	26627737	GBM cells	viability after 13 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	-0.07903643333986038	[236]	[145,101]	-1	hSpCas9	negative selection	1010373
47567321	47567344	X	+	26627737	GBM cells	viability after 13 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.18013966292346906	[100]	[28,88]	2	hSpCas9	negative selection	1010374
47563039	47563062	X	-	26627737	GBM cells	viability after 21 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.10569060788879439	[205]	[133,107]	1	hSpCas9	negative selection	1092684
47563308	47563331	X	+	26627737	GBM cells	viability after 21 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.26788049659901103	[342]	[171,138]	-2	hSpCas9	negative selection	1092685
47565061	47565084	X	-	26627737	GBM cells	viability after 21 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.5512297475762966	[211]	[87,69]	-5	hSpCas9	negative selection	1092686
47565262	47565285	X	+	26627737	GBM cells	viability after 21 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.6331404376508862	[125]	[113,98]	6	hSpCas9	negative selection	1092687
47566722	47566745	X	-	26627737	GBM cells	viability after 21 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.3216101898688485	[236]	[162,158]	3	hSpCas9	negative selection	1092688
47567321	47567344	X	+	26627737	GBM cells	viability after 21 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.032522046965391294	[100]	[64,47]	0	hSpCas9	negative selection	1092689
47563039	47563062	X	-	26627737	RPE1	viability after 9 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.19778452229213256	[1080]	[247,568]	1	hSpCas9	negative selection	1174999
47563308	47563331	X	+	26627737	RPE1	viability after 9 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.13939069838531779	[873]	[209,297]	-1	hSpCas9	negative selection	1175000
47565061	47565084	X	-	26627737	RPE1	viability after 9 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.061958055696242575	[786]	[249,217]	0	hSpCas9	negative selection	1175001
47565262	47565285	X	+	26627737	RPE1	viability after 9 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.9501878847647118	[188]	[119,106]	6	hSpCas9	negative selection	1175002
47566722	47566745	X	-	26627737	RPE1	viability after 9 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	2.769541857278126	[234]	[309,748]	9	hSpCas9	negative selection	1175003
47567321	47567344	X	+	26627737	RPE1	viability after 9 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	5.975879657974891	[3]	[49,115]	9	hSpCas9	negative selection	1175004
47563039	47563062	X	-	26627737	RPE1	viability after 12 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.04897601361156695	[1080]	[349,247]	0	hSpCas9	negative selection	1257314
47563308	47563331	X	+	26627737	RPE1	viability after 12 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.10172075164415201	[873]	[161,278]	0	hSpCas9	negative selection	1257315
47565061	47565084	X	-	26627737	RPE1	viability after 12 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.05249153085901029	[786]	[165,243]	0	hSpCas9	negative selection	1257316
47565262	47565285	X	+	26627737	RPE1	viability after 12 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.6027952319739502	[188]	[212,91]	8	hSpCas9	negative selection	1257317
47566722	47566745	X	-	26627737	RPE1	viability after 12 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	2.7554647411012345	[234]	[335,521]	9	hSpCas9	negative selection	1257318
47567321	47567344	X	+	26627737	RPE1	viability after 12 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	6.502384418639706	[3]	[94,99]	9	hSpCas9	negative selection	1257319
47563039	47563062	X	-	26627737	RPE1	viability after 15 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.7105634409727459	[1080]	[617,386]	4	hSpCas9	negative selection	1339629
47563308	47563331	X	+	26627737	RPE1	viability after 15 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.01788342050182412	[873]	[147,348]	0	hSpCas9	negative selection	1339630
47565061	47565084	X	-	26627737	RPE1	viability after 15 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.02427649664298706	[786]	[259,193]	0	hSpCas9	negative selection	1339631
47565262	47565285	X	+	26627737	RPE1	viability after 15 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.3265939860420253	[188]	[156,111]	7	hSpCas9	negative selection	1339632
47566722	47566745	X	-	26627737	RPE1	viability after 15 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	2.5669191913141316	[234]	[286,496]	9	hSpCas9	negative selection	1339633
47567321	47567344	X	+	26627737	RPE1	viability after 15 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	6.061622752876771	[3]	[14,133]	9	hSpCas9	negative selection	1339634
47563039	47563062	X	-	26627737	RPE1	viability after 18 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.2058074232742632	[1080]	[174,508]	1	hSpCas9	negative selection	1421944
47563308	47563331	X	+	26627737	RPE1	viability after 18 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.2597411720412838	[873]	[220,347]	1	hSpCas9	negative selection	1421945
47565061	47565084	X	-	26627737	RPE1	viability after 18 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-1.1536598072672128	[786]	[108,80]	-6	hSpCas9	negative selection	1421946
47565262	47565285	X	+	26627737	RPE1	viability after 18 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.8293478965684071	[188]	[217,141]	8	hSpCas9	negative selection	1421947
47566722	47566745	X	-	26627737	RPE1	viability after 18 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	2.8014869474741984	[234]	[241,655]	9	hSpCas9	negative selection	1421948
47567321	47567344	X	+	26627737	RPE1	viability after 18 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	6.885442107747776	[3]	[72,185]	9	hSpCas9	negative selection	1421949
47563039	47563062	X	-	26627737	HeLa	viability after 8 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	1.4705322572995587	[104]	[84,59,218]	8	hSpCas9	negative selection	1504259
47563308	47563331	X	+	26627737	HeLa	viability after 8 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.23312522141583714	[701]	[360,211,230]	-2	hSpCas9	negative selection	1504260
47565061	47565084	X	-	26627737	HeLa	viability after 8 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.019511219021678683	[533]	[389,131,202]	0	hSpCas9	negative selection	1504261
47565262	47565285	X	+	26627737	HeLa	viability after 8 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.34723969516821906	[264]	[203,165,86]	3	hSpCas9	negative selection	1504262
47566722	47566745	X	-	26627737	HeLa	viability after 8 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.9580788595561359	[184]	[139,234,94]	7	hSpCas9	negative selection	1504263
47567321	47567344	X	+	26627737	HeLa	viability after 8 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.6180434785403595	[326]	[161,121,14]	-6	hSpCas9	negative selection	1504264
47563039	47563062	X	-	26627737	HeLa	viability after 12 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	1.8731272981985159	[104]	[191,147,138]	9	hSpCas9	negative selection	1586574
47563308	47563331	X	+	26627737	HeLa	viability after 12 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.9516416166845671	[701]	[94,49,313]	-7	hSpCas9	negative selection	1586575
47565061	47565084	X	-	26627737	HeLa	viability after 12 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.1430943991327931	[533]	[252,143,209]	-1	hSpCas9	negative selection	1586576
47565262	47565285	X	+	26627737	HeLa	viability after 12 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.04597324677318604	[264]	[13,181,132]	0	hSpCas9	negative selection	1586577
47566722	47566745	X	-	26627737	HeLa	viability after 12 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	1.0541920501062263	[184]	[186,121,171]	7	hSpCas9	negative selection	1586578
47567321	47567344	X	+	26627737	HeLa	viability after 12 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.24267710170031304	[326]	[95,86,161]	-2	hSpCas9	negative selection	1586579
47563039	47563062	X	-	26627737	HeLa	viability after 15 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	2.1819769619349283	[104]	[69,373,134]	9	hSpCas9	negative selection	1668889
47563308	47563331	X	+	26627737	HeLa	viability after 15 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.5063168802519211	[701]	[263,134,203]	-4	hSpCas9	negative selection	1668890
47565061	47565084	X	-	26627737	HeLa	viability after 15 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.6776036015007089	[533]	[452,310,271]	5	hSpCas9	negative selection	1668891
47565262	47565285	X	+	26627737	HeLa	viability after 15 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.001604003706755619	[264]	[46,118,162]	0	hSpCas9	negative selection	1668892
47566722	47566745	X	-	26627737	HeLa	viability after 15 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.8257334015021862	[184]	[113,173,110]	6	hSpCas9	negative selection	1668893
47567321	47567344	X	+	26627737	HeLa	viability after 15 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.2285548204695376	[326]	[343,43,70]	2	hSpCas9	negative selection	1668894
47563039	47563062	X	-	26627737	HeLa	viability after 18 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	2.196006721484614	[104]	[51,307,134]	9	hSpCas9	negative selection	1751204
47563308	47563331	X	+	26627737	HeLa	viability after 18 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.4813282088772926	[701]	[182,112,203]	-4	hSpCas9	negative selection	1751205
47565061	47565084	X	-	26627737	HeLa	viability after 18 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.6836463175722501	[533]	[303,260,271]	5	hSpCas9	negative selection	1751206
47565262	47565285	X	+	26627737	HeLa	viability after 18 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.018239885778865594	[264]	[31,100,162]	0	hSpCas9	negative selection	1751207
47566722	47566745	X	-	26627737	HeLa	viability after 18 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.8193214395798334	[184]	[68,151,110]	6	hSpCas9	negative selection	1751208
47567321	47567344	X	+	26627737	HeLa	viability after 18 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.2230311087465227	[326]	[225,40,70]	2	hSpCas9	negative selection	1751209
47563039	47563062	X	-	26627737	HCT116	viability after 6 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.26328768729569646	[690]	[257,59]	1	hSpCas9	negative selection	1833519
47563308	47563331	X	+	26627737	HCT116	viability after 6 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.06494549785775172	[890]	[219,105]	0	hSpCas9	negative selection	1833520
47565061	47565084	X	-	26627737	HCT116	viability after 6 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.6455404414700445	[488]	[130,3]	-4	hSpCas9	negative selection	1833521
47565262	47565285	X	+	26627737	HCT116	viability after 6 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-1.5337601089540416	[297]	[1,23]	-7	hSpCas9	negative selection	1833522
47566722	47566745	X	-	26627737	HCT116	viability after 6 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.094214666303852	[324]	[11,77]	0	hSpCas9	negative selection	1833523
47567321	47567344	X	+	26627737	HCT116	viability after 6 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-1.1183379287510684	[948]	[11,99]	-6	hSpCas9	negative selection	1833524
47563039	47563062	X	-	26627737	HCT116	viability after 8 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.46881897857011584	[411]	[61,157,268]	-5	hSpCas9	negative selection	1915834
47563308	47563331	X	+	26627737	HCT116	viability after 8 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.42437984672071705	[600]	[231,256,250]	-5	hSpCas9	negative selection	1915835
47565061	47565084	X	-	26627737	HCT116	viability after 8 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.41254442213891823	[475]	[259,110,220]	-5	hSpCas9	negative selection	1915836
47565262	47565285	X	+	26627737	HCT116	viability after 8 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.4141762720023193	[228]	[205,203,95]	4	hSpCas9	negative selection	1915837
47566722	47566745	X	-	26627737	HCT116	viability after 8 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.8291625024915386	[217]	[236,216,186]	7	hSpCas9	negative selection	1915838
47567321	47567344	X	+	26627737	HCT116	viability after 8 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.8173007129958489	[122]	[77,114,163]	7	hSpCas9	negative selection	1915839
47563039	47563062	X	-	26627737	HCT116	viability after 9 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-1.0725581701157683	[690]	[137,47]	-6	hSpCas9	negative selection	1998149
47563308	47563331	X	+	26627737	HCT116	viability after 9 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.4064155727533628	[890]	[250,122]	-3	hSpCas9	negative selection	1998150
47565061	47565084	X	-	26627737	HCT116	viability after 9 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	1.2572011830082668	[488]	[291,327]	8	hSpCas9	negative selection	1998151
47565262	47565285	X	+	26627737	HCT116	viability after 9 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.17145118584158536	[297]	[78,97]	1	hSpCas9	negative selection	1998152
47566722	47566745	X	-	26627737	HCT116	viability after 9 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	1.175536366483954	[324]	[357,67]	7	hSpCas9	negative selection	1998153
47567321	47567344	X	+	26627737	HCT116	viability after 9 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.7645366611048946	[948]	[180,123]	-5	hSpCas9	negative selection	1998154
47563039	47563062	X	-	26627737	HCT116	viability after 12 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.3126317548969013	[411]	[182,81,254]	-3	hSpCas9	negative selection	2080464
47563308	47563331	X	+	26627737	HCT116	viability after 12 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.7669654487105262	[600]	[147,221,190]	-7	hSpCas9	negative selection	2080465
47565061	47565084	X	-	26627737	HCT116	viability after 12 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.23593347172311563	[475]	[197,232,207]	-2	hSpCas9	negative selection	2080466
47565262	47565285	X	+	26627737	HCT116	viability after 12 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.5485436840322309	[228]	[131,302,99]	5	hSpCas9	negative selection	2080467
47566722	47566745	X	-	26627737	HCT116	viability after 12 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.5281511960478098	[217]	[176,222,95]	5	hSpCas9	negative selection	2080468
47567321	47567344	X	+	26627737	HCT116	viability after 12 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.8271458394911703	[122]	[76,99,169]	7	hSpCas9	negative selection	2080469
47563039	47563062	X	-	26627737	HCT116	viability after 15 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.1380252584661245	[411]	[268,114,266]	-1	hSpCas9	negative selection	2162779
47563308	47563331	X	+	26627737	HCT116	viability after 15 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.4420244092495591	[600]	[237,164,355]	-4	hSpCas9	negative selection	2162780
47565061	47565084	X	-	26627737	HCT116	viability after 15 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.15911825977896932	[475]	[326,217,199]	-2	hSpCas9	negative selection	2162781
47565262	47565285	X	+	26627737	HCT116	viability after 15 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.7747757786104494	[228]	[237,328,110]	6	hSpCas9	negative selection	2162782
47566722	47566745	X	-	26627737	HCT116	viability after 15 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.8576651175906012	[217]	[171,280,220]	7	hSpCas9	negative selection	2162783
47567321	47567344	X	+	26627737	HCT116	viability after 15 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.48903470579388375	[122]	[167,54,82]	4	hSpCas9	negative selection	2162784
47563039	47563062	X	-	26627737	HCT116	viability after 18 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.24285808533104342	[411]	[203,103,415]	2	hSpCas9	negative selection	2245094
47563308	47563331	X	+	26627737	HCT116	viability after 18 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.5217287038869274	[600]	[220,195,189]	-5	hSpCas9	negative selection	2245095
47565061	47565084	X	-	26627737	HCT116	viability after 18 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	-0.22799952876842589	[475]	[242,146,202]	-2	hSpCas9	negative selection	2245096
47565262	47565285	X	+	26627737	HCT116	viability after 18 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.48673219899346	[228]	[526,193,212]	9	hSpCas9	negative selection	2245097
47566722	47566745	X	-	26627737	HCT116	viability after 18 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.9984483221208151	[217]	[192,214,223]	7	hSpCas9	negative selection	2245098
47567321	47567344	X	+	26627737	HCT116	viability after 18 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.2752058133997699	[122]	[14,40,93]	-3	hSpCas9	negative selection	2245099
47562960	47562983	X	+	24336569	HL60	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	-0.009925813474911505	[776]	[1632]	0	hSpCas9	negative selection	2248348
47563000	47563023	X	+	24336569	HL60	viability	GGCCGAGCCATCCCGGGCAGTGG	ARAF	ENSG00000078061	0.7173393081566646	[700]	[2438]	6	hSpCas9	negative selection	2248349
47563007	47563030	X	-	24336569	HL60	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.7809256634615809	[675]	[2457]	6	hSpCas9	negative selection	2248350
47563012	47563035	X	-	24336569	HL60	viability	CTTTGACGGTGCCCACTGCCCGG	ARAF	ENSG00000078061	-0.4558062898992575	[500]	[772]	-4	hSpCas9	negative selection	2248351
47563026	47563049	X	-	24336569	HL60	viability	GTTGGGCAGGTATACTTTGACGG	ARAF	ENSG00000078061	0.29407595609354276	[485]	[1260]	2	hSpCas9	negative selection	2248352
47563039	47563062	X	+	24336569	HL60	viability	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	0.6309313194204933	[1136]	[3725]	5	hSpCas9	negative selection	2248353
47563044	47563067	X	-	24336569	HL60	viability	CACCACCGTGCGTTGCTTGTTGG	ARAF	ENSG00000078061	1.2725932074286221	[372]	[1906]	8	hSpCas9	negative selection	2248354
47563215	47563238	X	+	24336569	HL60	viability	CATACACACAGGTGACTGTCCGG	ARAF	ENSG00000078061	0.48630863879474484	[984]	[2919]	4	hSpCas9	negative selection	2248355
47563220	47563243	X	+	24336569	HL60	viability	ACACAGGTGACTGTCCGGGATGG	ARAF	ENSG00000078061	1.6045419860259584	[84]	[546]	9	hSpCas9	negative selection	2248356
47563234	47563257	X	-	24336569	HL60	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	-0.4488764338882609	[873]	[1354]	-4	hSpCas9	negative selection	2248357
47562960	47562983	X	+	24336569	KBM7	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.7027169981444974	[591]	[2627]	6	hSpCas9	negative selection	2315525
47563000	47563023	X	+	24336569	KBM7	viability	GGCCGAGCCATCCCGGGCAGTGG	ARAF	ENSG00000078061	0.012428386581082473	[682]	[1878]	0	hSpCas9	negative selection	2315526
47563007	47563030	X	-	24336569	KBM7	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.7214928961834635	[375]	[1690]	6	hSpCas9	negative selection	2315527
47563012	47563035	X	-	24336569	KBM7	viability	CTTTGACGGTGCCCACTGCCCGG	ARAF	ENSG00000078061	0.8854513519068896	[232]	[1173]	7	hSpCas9	negative selection	2315528
47563026	47563049	X	-	24336569	KBM7	viability	GTTGGGCAGGTATACTTTGACGG	ARAF	ENSG00000078061	0.7137837913900059	[337]	[1511]	6	hSpCas9	negative selection	2315529
47563039	47563062	X	+	24336569	KBM7	viability	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	0.25521979446613186	[1268]	[4130]	2	hSpCas9	negative selection	2315530
47563044	47563067	X	-	24336569	KBM7	viability	CACCACCGTGCGTTGCTTGTTGG	ARAF	ENSG00000078061	2.0337331085036396	[231]	[2590]	9	hSpCas9	negative selection	2315531
47563215	47563238	X	+	24336569	KBM7	viability	CATACACACAGGTGACTGTCCGG	ARAF	ENSG00000078061	0.8784604950119097	[910]	[4567]	7	hSpCas9	negative selection	2315532
47563220	47563243	X	+	24336569	KBM7	viability	ACACAGGTGACTGTCCGGGATGG	ARAF	ENSG00000078061	-0.15394014609294393	[205]	[504]	-1	hSpCas9	negative selection	2315533
47563234	47563257	X	-	24336569	KBM7	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.8673716829587133	[455]	[2268]	7	hSpCas9	negative selection	2315534
47564834	47564857	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	-0.3350360935072469	[3,3]	[3,0]	-5	hSpCas9	positive selection	2971136
47563040	47563063	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	-0.0016637578179420354	[1,2]	[3,0]	0	hSpCas9	positive selection	2971137
47562963	47562986	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	-0.1272849325105262	[3,2]	[2,1]	-2	hSpCas9	positive selection	2971138
47563309	47563332	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.38971913811462644	[4,4]	[6,3]	7	hSpCas9	positive selection	2971139
47564834	47564857	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.6725838378893367	[3,3]	[4,3]	9	hSpCas9	positive selection	3038994
47563040	47563063	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	1.2676360140877638	[1,1]	[4,3]	9	hSpCas9	positive selection	3038995
47562963	47562986	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	0.2615065818828544	[3,3]	[5,1]	4	hSpCas9	positive selection	3038996
47563309	47563332	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.40531525430651194	[4,4]	[3,4]	7	hSpCas9	positive selection	3038997
47564987	47565010		+	24336571	A375	resistance to PLX after 7 days	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.4386494373377071	[18,17]	[26,23]	9	hSpCas9	positive selection	3125235
47563234	47563257		-	24336571	A375	resistance to PLX after 7 days	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.0385610759984103	[61,54]	[57,60]	1	hSpCas9	positive selection	3125246
47563306	47563329		+	24336571	A375	resistance to PLX after 7 days	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.11760766424100288	[40,40]	[34,39]	-4	hSpCas9	positive selection	3125257
47564987	47565010		+	24336571	A375	resistance to PLX after 14 days	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.0819664270606042	[20,17]	[9,8]	0	hSpCas9	positive selection	3183028
47563234	47563257		-	24336571	A375	resistance to PLX after 14 days	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	-0.04025598860199775	[62,60]	[27,26]	0	hSpCas9	positive selection	3183039
47563306	47563329		+	24336571	A375	resistance to PLX after 14 days	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.5110597861261252	[42,42]	[13,13]	-6	hSpCas9	positive selection	3183050
47564987	47565010		+	24336571	A375	viability after 7 days	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	-0.03069316929692545	[19]	[18,17]	0	hSpCas9	negative selection	3240821
47563234	47563257		-	24336571	A375	viability after 7 days	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.4077412185081126	[45]	[61,54]	6	hSpCas9	negative selection	3240832
47563306	47563329		+	24336571	A375	viability after 7 days	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.23950489384554774	[36]	[40,40]	3	hSpCas9	negative selection	3240843
47564987	47565010		+	24336571	A375	viability after 14 days	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.046345205219003094	[19]	[20,17]	0	hSpCas9	negative selection	3298614
47563234	47563257		-	24336571	A375	viability after 14 days	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.5093583991081543	[45]	[62,60]	6	hSpCas9	negative selection	3298625
47563306	47563329		+	24336571	A375	viability after 14 days	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.3239789048352901	[36]	[42,42]	4	hSpCas9	negative selection	3298636
47563306	47563329	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.3411277419114538	[163,223]	[0,0]	-2	hSpCas9	positive selection	3337165
47563234	47563257	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	-1.3806482162024047	[378,417]	[0,0]	-8	hSpCas9	positive selection	3337166
47564987	47565010	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	-0.728534323818992	[253,252]	[0,0]	-5	hSpCas9	positive selection	3337167
47565127	47565150	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	1.6874706031148872	[94,94]	[1,1]	6	hSpCas9	positive selection	3356411
47566890	47566913	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	-0.7760967900916153	[261,261]	[0,0]	-5	hSpCas9	positive selection	3356412
47566892	47566915	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.37468316208399377	[235,235]	[1,1]	2	hSpCas9	positive selection	3356413
47564834	47564857	X	-	26780180	HT29	viability (Avana library 4 designs)	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	2.0028457106384	[]	[]	7	hSpCas9	negative selection	3407248
47563039	47563062	X	+	26780180	HT29	viability (Avana library 4 designs)	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	1.29923819789189	[]	[]	5	hSpCas9	negative selection	3407249
47562962	47562985	X	+	26780180	HT29	viability (Avana library 4 designs)	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	-0.0717606920140453	[]	[]	-1	hSpCas9	negative selection	3407250
47563308	47563331	X	+	26780180	HT29	viability (Avana library 4 designs)	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	1.62946011119301	[]	[]	6	hSpCas9	negative selection	3407251
47562962	47562985	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	5.74531052936767	[]	[]	9	hSpCas9	negative selection	3480200
47563039	47563062	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	-3.26239583322196	[]	[]	-4	hSpCas9	negative selection	3480201
47563308	47563331	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	1.43904977355861	[]	[]	2	hSpCas9	negative selection	3480202
47564834	47564857	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	3.05387587981419	[]	[]	5	hSpCas9	negative selection	3480203
47564785	47564808	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCCCCCTGCAGACGAAAGACGG	ARAF	ENSG00000078061	0.602398623321962	[]	[]	0	hSpCas9	negative selection	3480204
47563042	47563065	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	1.29257788723545	[]	[]	1	hSpCas9	negative selection	3480205
47562962	47562985	X	+	26780180	A375	viability (Avana lentiGuide)	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	-1.91177474534304	[]	[]	-3	hSpCas9	negative selection	3588859
47563039	47563062	X	+	26780180	A375	viability (Avana lentiGuide)	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	2.0794703182608	[]	[]	2	hSpCas9	negative selection	3588860
47563308	47563331	X	+	26780180	A375	viability (Avana lentiGuide)	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-1.3038640108988	[]	[]	-2	hSpCas9	negative selection	3588861
47564834	47564857	X	-	26780180	A375	viability (Avana lentiGuide)	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	2.30377171611392	[]	[]	2	hSpCas9	negative selection	3588862
47564785	47564808	X	+	26780180	A375	viability (Avana lentiGuide)	TGCCCCCTGCAGACGAAAGACGG	ARAF	ENSG00000078061	-2.3435242661686	[]	[]	-4	hSpCas9	negative selection	3588863
47563042	47563065	X	+	26780180	A375	viability (Avana lentiGuide)	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	-2.69599980310293	[]	[]	-5	hSpCas9	negative selection	3588864
47562962	47562985	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	0.3512171668125937	[4]	[5,5]	9	hSpCas9	positive selection	3697518
47563039	47563062	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	-0.6763290604719326	[3]	[3,0]	-7	hSpCas9	positive selection	3697519
47563308	47563331	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.055045554040570516	[5]	[6,5]	1	hSpCas9	positive selection	3697520
47564834	47564857	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.21433638129172033	[5]	[6,6]	6	hSpCas9	positive selection	3697521
47564785	47564808	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCCCCCTGCAGACGAAAGACGG	ARAF	ENSG00000078061	0.15358176648718444	[5]	[6,5]	4	hSpCas9	positive selection	3697522
47563042	47563065	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	-0.16820676375671995	[4]	[5,2]	-3	hSpCas9	positive selection	3697523
47562962	47562985	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCCATGGAGCCACCACGGGG	ARAF	ENSG00000078061	0.025646708478198513	[4]	[3,4]	0	hSpCas9	positive selection	3806125
47563039	47563062	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCCCAACAAGCAACGCACGG	ARAF	ENSG00000078061	-0.7521380666442591	[4]	[2,1]	-7	hSpCas9	positive selection	3806126
47563308	47563331	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.1963361982838875	[6]	[7,4]	5	hSpCas9	positive selection	3806127
47564834	47564857	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	-0.14453919166550608	[5]	[4,3]	-2	hSpCas9	positive selection	3806128
47564785	47564808	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCCCCCTGCAGACGAAAGACGG	ARAF	ENSG00000078061	0.20136331691369008	[6]	[6,6]	5	hSpCas9	positive selection	3806129
47563042	47563065	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.39234155408572036	[5]	[6,6]	9	hSpCas9	positive selection	3806130
47564987	47565010	X	+	26780180	A375	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	1.07817074939217	[]	[]	5	hSpCas9	negative selection	3914386
47566892	47566915	X	-	26780180	A375	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.45934817419762	[]	[]	1	hSpCas9	negative selection	3914387
47563234	47563257	X	-	26780180	A375	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	1.38622598557771	[]	[]	7	hSpCas9	negative selection	3914388
47565127	47565150	X	-	26780180	A375	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	1.00976273454191	[]	[]	5	hSpCas9	negative selection	3914389
47566890	47566913	X	+	26780180	A375	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.425600088587828	[]	[]	1	hSpCas9	negative selection	3914390
47563306	47563329	X	+	26780180	A375	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.331785306030688	[]	[]	0	hSpCas9	negative selection	3914391
47564987	47565010	X	+	26780180	HT29	viability (GeCKOv2 library)	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.953253771306347	[]	[]	4	hSpCas9	negative selection	4022352
47566892	47566915	X	-	26780180	HT29	viability (GeCKOv2 library)	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.645088691123042	[]	[]	2	hSpCas9	negative selection	4022353
47563234	47563257	X	-	26780180	HT29	viability (GeCKOv2 library)	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	1.83719381364069	[]	[]	8	hSpCas9	negative selection	4022354
47565127	47565150	X	-	26780180	HT29	viability (GeCKOv2 library)	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.675808597104156	[]	[]	2	hSpCas9	negative selection	4022355
47566890	47566913	X	+	26780180	HT29	viability (GeCKOv2 library)	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.294228115704148	[]	[]	0	hSpCas9	negative selection	4022356
47563306	47563329	X	+	26780180	HT29	viability (GeCKOv2 library)	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	1.13684573987436	[]	[]	5	hSpCas9	negative selection	4022357
47564987	47565010	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.09567975285720542	[4]	[2,3]	2	hSpCas9	positive selection	4149359
47563234	47563257	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.15042925144122204	[5]	[3,4]	4	hSpCas9	positive selection	4149370
47563306	47563329	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.2101647982528414	[4]	[3,3]	5	hSpCas9	positive selection	4149381
47564987	47565010	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.9454928141325454	[4]	[3,4,3,3]	6	hSpCas9	positive selection	4213381
47563234	47563257	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.6766417906456378	[3]	[4,4,4,0]	4	hSpCas9	positive selection	4213392
47563306	47563329	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	1.1411105124960472	[5]	[4,4,4,4]	8	hSpCas9	positive selection	4213403
47563306	47563329	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.017125333238208057	[3]	[3,2]	0	hSpCas9	positive selection	4256323
47563234	47563257	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.005245037284548226	[4]	[3,2]	0	hSpCas9	positive selection	4256324
47564987	47565010	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	-0.11279252600752551	[3]	[2,1]	-2	hSpCas9	positive selection	4256325
47565127	47565150	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.31257114496390126	[2]	[2,1]	6	hSpCas9	positive selection	4320607
47566890	47566913	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.10878288111928273	[3]	[3,1]	2	hSpCas9	positive selection	4320608
47566892	47566915	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.3739405605278485	[3]	[3,0]	-7	hSpCas9	positive selection	4320609
47563234	47563256	X	-	27760321	OCIAML3	viability	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.9235293798990778	[611,468]	[615,1029]	9	hSpCas9	negative selection	4378931
47563307	47563329	X	+	27760321	OCIAML3	viability	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.2875621414682654	[403,418]	[247,286]	-3	hSpCas9	negative selection	4378932
47564797	47564819	X	+	27760321	OCIAML3	viability	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.4076670292264083	[453,299]	[374,399]	5	hSpCas9	negative selection	4378933
47564834	47564856	X	-	27760321	OCIAML3	viability	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.31608888899864274	[590,530]	[496,608]	3	hSpCas9	negative selection	4378934
47564878	47564900	X	-	27760321	OCIAML3	viability	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.1657230465795385	[900,827]	[713,815]	2	hSpCas9	negative selection	4378935
47563234	47563256	X	-	27760321	OCIAML2	viability	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	1.1118241257901764	[611,468]	[819,1092]	9	hSpCas9	negative selection	4462394
47563307	47563329	X	+	27760321	OCIAML2	viability	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.746755236449668	[403,418]	[543,583]	8	hSpCas9	negative selection	4462395
47564797	47564819	X	+	27760321	OCIAML2	viability	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.2117991957897336	[453,299]	[262,460]	2	hSpCas9	negative selection	4462396
47564834	47564856	X	-	27760321	OCIAML2	viability	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.6261974883987369	[590,530]	[700,697]	8	hSpCas9	negative selection	4462397
47564878	47564900	X	-	27760321	OCIAML2	viability	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.21494161314572668	[900,827]	[584,1109]	3	hSpCas9	negative selection	4462398
47563234	47563256	X	-	27760321	MV411	viability	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.4513657283877762	[611,468]	[485,480]	3	hSpCas9	negative selection	4545857
47563307	47563329	X	+	27760321	MV411	viability	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.3090901884484315	[403,418]	[13,529]	-2	hSpCas9	negative selection	4545858
47564797	47564819	X	+	27760321	MV411	viability	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.27823329939925096	[453,299]	[96,598]	2	hSpCas9	negative selection	4545859
47564834	47564856	X	-	27760321	MV411	viability	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	1.0308179817722252	[590,530]	[705,829]	7	hSpCas9	negative selection	4545860
47564878	47564900	X	-	27760321	MV411	viability	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	1.786165333420857	[900,827]	[2720,834]	9	hSpCas9	negative selection	4545861
47563234	47563256	X	-	27760321	HL60	viability	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	-0.03883623254524421	[611,468]	[460,389]	0	hSpCas9	negative selection	4629320
47563307	47563329	X	+	27760321	HL60	viability	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.4130084179754947	[403,418]	[472,424]	5	hSpCas9	negative selection	4629321
47564797	47564819	X	+	27760321	HL60	viability	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.5690432287522202	[453,299]	[374,530]	6	hSpCas9	negative selection	4629322
47564834	47564856	X	-	27760321	HL60	viability	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.009030760816156835	[590,530]	[431,490]	0	hSpCas9	negative selection	4629323
47564878	47564900	X	-	27760321	HL60	viability	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.4904231214245993	[900,827]	[955,1029]	6	hSpCas9	negative selection	4629324
47563234	47563256	X	-	27760321	HT1080	viability	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	1.1994383785711438	[468,365]	[401,359]	6	hSpCas9	negative selection	4712783
47563307	47563329	X	+	27760321	HT1080	viability	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	1.0353103819966674	[418,326]	[294,314]	5	hSpCas9	negative selection	4712784
47564797	47564819	X	+	27760321	HT1080	viability	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	1.6745085646134237	[299,233]	[244,442]	8	hSpCas9	negative selection	4712785
47564834	47564856	X	-	27760321	HT1080	viability	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	1.7252871688396312	[530,414]	[645,597]	8	hSpCas9	negative selection	4712786
47564878	47564900	X	-	27760321	HT1080	viability	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	-0.0729930851580417	[827,645]	[175,391]	0	hSpCas9	negative selection	4712787
47563234	47563256	X	-	27760321	HT29	viability after 7 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.3422771367796741	[468,365]	[924,647,507]	5	hSpCas9	negative selection	4796246
47563307	47563329	X	+	27760321	HT29	viability after 7 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.1950037413083445	[418,326]	[554,345,375]	-3	hSpCas9	negative selection	4796247
47564797	47564819	X	+	27760321	HT29	viability after 7 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.3493045524298624	[299,233]	[280,474,529]	5	hSpCas9	negative selection	4796248
47564834	47564856	X	-	27760321	HT29	viability after 7 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.4840287337664842	[530,414]	[958,687,916]	7	hSpCas9	negative selection	4796249
47564878	47564900	X	-	27760321	HT29	viability after 7 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	-0.4514022848415431	[827,645]	[798,758,539]	-6	hSpCas9	negative selection	4796250
47563234	47563256	X	-	27760321	HT29	viability after 25 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.6036085570196283	[468,365]	[537,962,679]	6	hSpCas9	negative selection	4879709
47563307	47563329	X	+	27760321	HT29	viability after 25 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.031411947112164065	[418,326]	[371,390,498]	0	hSpCas9	negative selection	4879710
47564797	47564819	X	+	27760321	HT29	viability after 25 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.9563326941280119	[299,233]	[523,469,807]	9	hSpCas9	negative selection	4879711
47564834	47564856	X	-	27760321	HT29	viability after 25 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.7107204137114134	[530,414]	[854,766,1049]	7	hSpCas9	negative selection	4879712
47564878	47564900	X	-	27760321	HT29	viability after 25 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.24121202746293613	[827,645]	[639,987,1423]	2	hSpCas9	negative selection	4879713
47563234	47563256	X	-	27760321	HT29	viability after 22 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.6816110564796953	[468,365]	[598,859,868]	7	hSpCas9	negative selection	4963172
47563307	47563329	X	+	27760321	HT29	viability after 22 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.26046602699631005	[418,326]	[265,399,416]	-3	hSpCas9	negative selection	4963173
47564797	47564819	X	+	27760321	HT29	viability after 22 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.7412609540191237	[299,233]	[410,381,759]	8	hSpCas9	negative selection	4963174
47564834	47564856	X	-	27760321	HT29	viability after 22 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.8611145059825338	[530,414]	[695,880,1414]	8	hSpCas9	negative selection	4963175
47564878	47564900	X	-	27760321	HT29	viability after 22 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.10369198455649231	[827,645]	[803,968,976]	1	hSpCas9	negative selection	4963176
47563234	47563256	X	-	27760321	HT29	viability after 19 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.5369841816164892	[468,365]	[601,976,496]	5	hSpCas9	negative selection	5046635
47563307	47563329	X	+	27760321	HT29	viability after 19 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.6458996980877316	[418,326]	[514,801,668]	6	hSpCas9	negative selection	5046636
47564797	47564819	X	+	27760321	HT29	viability after 19 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.2910752073166739	[299,233]	[283,206,610]	2	hSpCas9	negative selection	5046637
47564834	47564856	X	-	27760321	HT29	viability after 19 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.7041482629636453	[530,414]	[720,1136,772]	7	hSpCas9	negative selection	5046638
47564878	47564900	X	-	27760321	HT29	viability after 19 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.4135852023652764	[827,645]	[1140,1098,1128]	4	hSpCas9	negative selection	5046639
47563234	47563256	X	-	27760321	HT29	viability after 16 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.4799433653873123	[468,365]	[543,808,586]	5	hSpCas9	negative selection	5130098
47563307	47563329	X	+	27760321	HT29	viability after 16 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.021886592589300424	[418,326]	[767,290,247]	0	hSpCas9	negative selection	5130099
47564797	47564819	X	+	27760321	HT29	viability after 16 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.5415249879223667	[299,233]	[511,340,460]	6	hSpCas9	negative selection	5130100
47564834	47564856	X	-	27760321	HT29	viability after 16 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.7921244238633058	[530,414]	[750,975,1004]	8	hSpCas9	negative selection	5130101
47564878	47564900	X	-	27760321	HT29	viability after 16 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.05686583452424898	[827,645]	[1037,664,891]	0	hSpCas9	negative selection	5130102
47563234	47563256	X	-	27760321	HT29	viability after 13 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.26061923101733286	[468,365]	[541,742,462]	3	hSpCas9	negative selection	5213561
47563307	47563329	X	+	27760321	HT29	viability after 13 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.059760029054343605	[418,326]	[328,636,390]	0	hSpCas9	negative selection	5213562
47564797	47564819	X	+	27760321	HT29	viability after 13 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.6390151493123354	[299,233]	[566,452,429]	8	hSpCas9	negative selection	5213563
47564834	47564856	X	-	27760321	HT29	viability after 13 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.32962875771177574	[530,414]	[687,455,910]	4	hSpCas9	negative selection	5213564
47564878	47564900	X	-	27760321	HT29	viability after 13 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	-0.09912781704510665	[827,645]	[638,823,923]	-1	hSpCas9	negative selection	5213565
47563234	47563256	X	-	27760321	HT29	viability after 10 days	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.0769905084683789	[468,365]	[715,566,370]	1	hSpCas9	negative selection	5297024
47563307	47563329	X	+	27760321	HT29	viability after 10 days	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.0259018756053857	[418,326]	[524,282,556]	0	hSpCas9	negative selection	5297025
47564797	47564819	X	+	27760321	HT29	viability after 10 days	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	0.6748308944401527	[299,233]	[528,364,693]	8	hSpCas9	negative selection	5297026
47564834	47564856	X	-	27760321	HT29	viability after 10 days	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	0.3620180531694775	[530,414]	[756,737,780]	5	hSpCas9	negative selection	5297027
47564878	47564900	X	-	27760321	HT29	viability after 10 days	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	-0.06478176145573189	[827,645]	[675,887,1070]	-1	hSpCas9	negative selection	5297028
47563234	47563256	X	-	27760321	MOLM13	viability	GTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	1.215362323845922	[611,468]	[766,647]	8	hSpCas9	negative selection	5380487
47563307	47563329	X	+	27760321	MOLM13	viability	GTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.33232097317750353	[403,418]	[315,73]	-2	hSpCas9	negative selection	5380488
47564797	47564819	X	+	27760321	MOLM13	viability	ACGAAAGACGGTCACTGCCTGG	ARAF	ENSG00000078061	2.036837092684259	[453,299]	[651,1038]	9	hSpCas9	negative selection	5380489
47564834	47564856	X	-	27760321	MOLM13	viability	TGAGCTCCTCGCCATCCAGGGG	ARAF	ENSG00000078061	-0.33042201943399474	[590,530]	[231,267]	-2	hSpCas9	negative selection	5380490
47564878	47564900	X	-	27760321	MOLM13	viability	AAAATTGTGCATGGTCAGCGGG	ARAF	ENSG00000078061	0.7541544049500182	[900,827]	[808,833]	5	hSpCas9	negative selection	5380491
47561161	47561184	X	+	27661255	K562	viability	GAGAGTCCGAGAGGCGACGGAGG	ARAF	ENSG00000078061	0.01771561630042129	[356,441]	[330,313]	0	dCas9-KRAB	negative selection	5463000
47561209	47561232	X	+	27661255	K562	viability	GAGGCCCAAGATGGAGACGGCGG	ARAF	ENSG00000078061	0.09296011412360772	[815,869]	[833,617]	3	dCas9-KRAB	negative selection	5463001
47561230	47561253	X	+	27661255	K562	viability	GGCGGCTGTAGCGGCGTGACAGG	ARAF	ENSG00000078061	-0.019989088229386387	[587,526]	[472,411]	-1	dCas9-KRAB	negative selection	5463002
47561516	47561539	X	+	27661255	K562	viability	GTAGGCGGGACCCGACCGAGTGG	ARAF	ENSG00000078061	0.002399997848750113	[1355,1300]	[1208,939]	0	dCas9-KRAB	negative selection	5463003
47561213	47561236	X	-	27661255	K562	viability	GCCGCCGCCGTCTCCATCTTGGG	ARAF	ENSG00000078061	-0.02027528774374372	[687,830]	[667,534]	-1	dCas9-KRAB	negative selection	5463004
47563306	47563329	X	+	27260156	BXPC3	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.24279728550935098	[817]	[909,965,1092,1097]	5	hSpCas9	negative selection	5528783
47563234	47563257	X	-	27260156	BXPC3	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.3128250179774137	[1160]	[1585,1494,1464,1459]	6	hSpCas9	negative selection	5528784
47564987	47565010	X	+	27260156	BXPC3	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.5147277163041627	[666]	[893,841,1022,1274]	9	hSpCas9	negative selection	5528785
47565127	47565150	X	-	27260156	BXPC3	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.24334660494404853	[307]	[391,331,398,403]	5	hSpCas9	negative selection	5593067
47566890	47566913	X	+	27260156	BXPC3	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.36335745943891024	[531]	[765,655,718,713]	7	hSpCas9	negative selection	5593068
47566892	47566915	X	-	27260156	BXPC3	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.0330646055722601	[723]	[796,771,694,831]	0	hSpCas9	negative selection	5593069
47563306	47563329	X	+	27260156	A673	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.1818147236692791	[817]	[1021,1167,1151,1098]	4	hSpCas9	negative selection	5650034
47563234	47563257	X	-	27260156	A673	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.19912558292111715	[1160]	[1810,1425,1461,1736]	5	hSpCas9	negative selection	5650035
47564987	47565010	X	+	27260156	A673	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.4782647317188802	[666]	[1255,1073,967,1184]	9	hSpCas9	negative selection	5650036
47565127	47565150	X	-	27260156	A673	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.27613788126776656	[307]	[442,473,386,487]	6	hSpCas9	negative selection	5714318
47566890	47566913	X	+	27260156	A673	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.3002760169928735	[531]	[678,742,766,953]	7	hSpCas9	negative selection	5714319
47566892	47566915	X	-	27260156	A673	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.028819080012460807	[723]	[894,851,814,849]	0	hSpCas9	negative selection	5714320
47563306	47563329	X	+	27260156	A375	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.26065851254499095	[817]	[1154,1311,1185,965]	4	hSpCas9	negative selection	5771285
47563234	47563257	X	-	27260156	A375	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.29923715408653684	[1160]	[1738,2077,1698,1258]	4	hSpCas9	negative selection	5771286
47564987	47565010	X	+	27260156	A375	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6916308482783445	[666]	[1139,1496,1299,1137]	8	hSpCas9	negative selection	5771287
47565127	47565150	X	-	27260156	A375	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.3120213913047446	[307]	[509,480,380,420]	4	hSpCas9	negative selection	5835569
47566890	47566913	X	+	27260156	A375	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.25812641058322067	[531]	[677,932,673,713]	4	hSpCas9	negative selection	5835570
47566892	47566915	X	-	27260156	A375	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.026454424602982862	[723]	[799,1047,707,795]	0	hSpCas9	negative selection	5835571
47563306	47563329	X	+	27260156	COLO741	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.31763052189204743	[817]	[1269,1188,1432]	6	hSpCas9	negative selection	5892536
47563234	47563257	X	-	27260156	COLO741	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.13933427264821896	[1160]	[1575,1612,1698]	3	hSpCas9	negative selection	5892537
47564987	47565010	X	+	27260156	COLO741	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6285190276851239	[666]	[1422,1407,1140]	9	hSpCas9	negative selection	5892538
47565127	47565150	X	-	27260156	COLO741	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.29388520948582664	[307]	[459,565,422]	6	hSpCas9	negative selection	5956820
47566890	47566913	X	+	27260156	COLO741	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.3969339787087725	[531]	[942,1015,739]	7	hSpCas9	negative selection	5956821
47566892	47566915	X	-	27260156	COLO741	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.024536927657162533	[723]	[963,1034,831]	0	hSpCas9	negative selection	5956822
47563306	47563329	X	+	27260156	CAL120	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.20055268349345667	[817]	[1407,825,1307]	3	hSpCas9	negative selection	6013787
47563234	47563257	X	-	27260156	CAL120	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.4005294922286218	[1160]	[3077,1274,1549]	6	hSpCas9	negative selection	6013788
47564987	47565010	X	+	27260156	CAL120	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.5172544147638426	[666]	[1482,1065,1060]	7	hSpCas9	negative selection	6013789
47565127	47565150	X	-	27260156	CAL120	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.17467692536715074	[307]	[254,252,494]	-3	hSpCas9	negative selection	6078071
47566890	47566913	X	+	27260156	CAL120	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.44567854399940493	[531]	[654,1366,649]	6	hSpCas9	negative selection	6078072
47566892	47566915	X	-	27260156	CAL120	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.18324841119202873	[723]	[1294,993,823]	2	hSpCas9	negative selection	6078073
47563306	47563329	X	+	27260156	CADOES1	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.242731560035363	[817]	[886,1082,837,788]	4	hSpCas9	negative selection	6135038
47563234	47563257	X	-	27260156	CADOES1	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.22403409701404975	[1160]	[1175,1277,1355,1233]	4	hSpCas9	negative selection	6135039
47564987	47565010	X	+	27260156	CADOES1	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6498221486877441	[666]	[975,1022,980,910]	9	hSpCas9	negative selection	6135040
47565127	47565150	X	-	27260156	CADOES1	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.15129053105084034	[307]	[301,309,406,250]	2	hSpCas9	negative selection	6199322
47566890	47566913	X	+	27260156	CADOES1	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.23939884186718113	[531]	[439,747,516,633]	4	hSpCas9	negative selection	6199323
47566892	47566915	X	-	27260156	CADOES1	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.1733897428009421	[723]	[759,796,631,851]	3	hSpCas9	negative selection	6199324
47563306	47563329	X	+	27260156	EWS502	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.14549904839453542	[817]	[746,1032,1026,1052]	2	hSpCas9	negative selection	6256289
47563234	47563257	X	-	27260156	EWS502	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.31443455217571703	[1160]	[1630,1433,1233,1819]	5	hSpCas9	negative selection	6256290
47564987	47565010	X	+	27260156	EWS502	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6005961617091945	[666]	[889,1196,1311,888]	9	hSpCas9	negative selection	6256291
47565127	47565150	X	-	27260156	EWS502	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.21736097863708076	[307]	[323,359,480,357]	4	hSpCas9	negative selection	6320573
47566890	47566913	X	+	27260156	EWS502	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.10901162463383768	[531]	[582,554,652,645]	1	hSpCas9	negative selection	6320574
47566892	47566915	X	-	27260156	EWS502	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.048602935006320624	[723]	[589,712,734,959]	-1	hSpCas9	negative selection	6320575
47563306	47563329	X	+	27260156	EW8	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	-0.16132800519091928	[817]	[699,574,648,447]	-3	hSpCas9	negative selection	6377540
47563234	47563257	X	-	27260156	EW8	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.06657822311645734	[1160]	[1244,987,767,1002]	1	hSpCas9	negative selection	6377541
47564987	47565010	X	+	27260156	EW8	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.47689141433946725	[666]	[891,838,592,725]	8	hSpCas9	negative selection	6377542
47565127	47565150	X	-	27260156	EW8	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.0550006768965684	[307]	[273,252,193,250]	-1	hSpCas9	negative selection	6441824
47566890	47566913	X	+	27260156	EW8	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.14319020854897052	[531]	[543,328,545,478]	2	hSpCas9	negative selection	6441825
47566892	47566915	X	-	27260156	EW8	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.07221124583256144	[723]	[780,415,466,605]	-1	hSpCas9	negative selection	6441826
47563306	47563329	X	+	27260156	CORL105	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.43357059318769986	[817]	[1145,1242,1905,970]	7	hSpCas9	negative selection	6498791
47563234	47563257	X	-	27260156	CORL105	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.16916434898074661	[1160]	[1378,1550,1475,1691]	3	hSpCas9	negative selection	6498792
47564987	47565010	X	+	27260156	CORL105	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.5564611043289268	[666]	[1201,1112,1231,1061]	8	hSpCas9	negative selection	6498793
47565127	47565150	X	-	27260156	CORL105	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.2589916945457498	[307]	[339,228,283,351]	-5	hSpCas9	negative selection	6563075
47566890	47566913	X	+	27260156	CORL105	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.04797218351155999	[531]	[733,476,760,627]	0	hSpCas9	negative selection	6563076
47566892	47566915	X	-	27260156	CORL105	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.22588034790151357	[723]	[874,599,840,608]	-4	hSpCas9	negative selection	6563077
47563306	47563329	X	+	27260156	HS294T	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.21589784156624492	[817]	[326,366,325,468]	3	hSpCas9	negative selection	6620042
47563234	47563257	X	-	27260156	HS294T	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.6706592012973023	[1160]	[753,846,593,639]	8	hSpCas9	negative selection	6620043
47564987	47565010	X	+	27260156	HS294T	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.41278214120889023	[666]	[272,365,311,443]	5	hSpCas9	negative selection	6620044
47565127	47565150	X	-	27260156	HS294T	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.16332796180773013	[307]	[89,126,126,76]	-2	hSpCas9	negative selection	6684326
47566890	47566913	X	+	27260156	HS294T	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.5232581706265302	[531]	[219,221,275,508]	7	hSpCas9	negative selection	6684327
47566892	47566915	X	-	27260156	HS294T	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.13894383682550637	[723]	[327,378,254,256]	2	hSpCas9	negative selection	6684328
47563306	47563329	X	+	27260156	HCC44	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.330576583635134	[817]	[1324,975,1345,1072]	5	hSpCas9	negative selection	6741293
47563234	47563257	X	-	27260156	HCC44	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.20614880653133905	[1160]	[1385,1418,1807,1486]	3	hSpCas9	negative selection	6741294
47564987	47565010	X	+	27260156	HCC44	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.623044391976857	[666]	[1473,901,1195,1137]	8	hSpCas9	negative selection	6741295
47565127	47565150	X	-	27260156	HCC44	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.15225056226121325	[307]	[259,297,315,372]	-2	hSpCas9	negative selection	6805577
47566890	47566913	X	+	27260156	HCC44	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	-0.04300870218627273	[531]	[691,383,861,482]	0	hSpCas9	negative selection	6805578
47566892	47566915	X	-	27260156	HCC44	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.24800254639130076	[723]	[903,462,832,630]	-4	hSpCas9	negative selection	6805579
47563306	47563329	X	+	27260156	G402	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.1725480932722755	[817]	[1044,1475,895,1088]	2	hSpCas9	negative selection	6862544
47563234	47563257	X	-	27260156	G402	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.3117512787863419	[1160]	[1666,1706,1719,1908]	4	hSpCas9	negative selection	6862545
47564987	47565010	X	+	27260156	G402	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.678162806245359	[666]	[1843,1061,1031,1328]	8	hSpCas9	negative selection	6862546
47565127	47565150	X	-	27260156	G402	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.02408875662085752	[307]	[430,326,433,340]	0	hSpCas9	negative selection	6926828
47566890	47566913	X	+	27260156	G402	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.2825291048454005	[531]	[1034,929,680,563]	3	hSpCas9	negative selection	6926829
47566892	47566915	X	-	27260156	G402	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.3572484139703796	[723]	[897,631,739,520]	-4	hSpCas9	negative selection	6926830
47563306	47563329	X	+	27260156	L33	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.13575889752767922	[817]	[883,384,576,853]	3	hSpCas9	negative selection	6983795
47563234	47563257	X	-	27260156	L33	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.16358425663688703	[1160]	[1269,460,966,1269]	3	hSpCas9	negative selection	6983796
47564987	47565010	X	+	27260156	L33	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.39335013111952954	[666]	[944,371,490,867]	7	hSpCas9	negative selection	6983797
47565127	47565150	X	-	27260156	L33	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.328120446453093	[307]	[297,125,140,150]	-6	hSpCas9	negative selection	7048079
47566890	47566913	X	+	27260156	L33	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.38696792877443015	[531]	[513,316,438,799]	7	hSpCas9	negative selection	7048080
47566892	47566915	X	-	27260156	L33	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.24785367234683298	[723]	[669,213,388,625]	-5	hSpCas9	negative selection	7048081
47563306	47563329	X	+	27260156	K562	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.4859127520253157	[817]	[1174,1258,534,1107]	6	hSpCas9	negative selection	7105046
47563234	47563257	X	-	27260156	K562	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.3970017439968718	[1160]	[1688,1114,1553,1106]	5	hSpCas9	negative selection	7105047
47564987	47565010	X	+	27260156	K562	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.35199456522643535	[666]	[536,1083,678,721]	4	hSpCas9	negative selection	7105048
47565127	47565150	X	-	27260156	K562	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.06838591172517872	[307]	[353,297,249,160]	-1	hSpCas9	negative selection	7169330
47566890	47566913	X	+	27260156	K562	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.5417122097943765	[531]	[633,805,790,534]	7	hSpCas9	negative selection	7169331
47566892	47566915	X	-	27260156	K562	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.3127453385528467	[723]	[737,1189,606,682]	4	hSpCas9	negative selection	7169332
47563306	47563329	X	+	27260156	HT29	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.15280839717145422	[817]	[1245,1411,1082,753]	3	hSpCas9	negative selection	7226297
47563234	47563257	X	-	27260156	HT29	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.20140082517543445	[1160]	[1524,1769,1509,1672]	4	hSpCas9	negative selection	7226298
47564987	47565010	X	+	27260156	HT29	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6296505854238464	[666]	[1221,1584,1155,1091]	9	hSpCas9	negative selection	7226299
47565127	47565150	X	-	27260156	HT29	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.10864336747147962	[307]	[535,432,354,311]	2	hSpCas9	negative selection	7290581
47566890	47566913	X	+	27260156	HT29	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.1701254680200346	[531]	[791,776,864,507]	3	hSpCas9	negative selection	7290582
47566892	47566915	X	-	27260156	HT29	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.01931506335467026	[723]	[891,1305,694,641]	0	hSpCas9	negative selection	7290583
47563306	47563329	X	+	27260156	MHHES1	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.13061854058478972	[817]	[1010,1035,1000,973]	2	hSpCas9	negative selection	7347548
47563234	47563257	X	-	27260156	MHHES1	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.12656342599750703	[1160]	[1493,1538,1397,1295]	2	hSpCas9	negative selection	7347549
47564987	47565010	X	+	27260156	MHHES1	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.4171762384020894	[666]	[1140,929,1086,871]	7	hSpCas9	negative selection	7347550
47565127	47565150	X	-	27260156	MHHES1	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.19643558028492425	[307]	[369,223,478,469]	3	hSpCas9	negative selection	7411832
47566890	47566913	X	+	27260156	MHHES1	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.32435738611010495	[531]	[926,1006,560,575]	6	hSpCas9	negative selection	7411833
47566892	47566915	X	-	27260156	MHHES1	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.5702869246274707	[723]	[773,486,551,421]	-8	hSpCas9	negative selection	7411834
47563306	47563329	X	+	27260156	MEWO	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.20776612062445876	[817]	[1090,767,832]	4	hSpCas9	negative selection	7468799
47563234	47563257	X	-	27260156	MEWO	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.3286789040899978	[1160]	[1538,1135,1451]	7	hSpCas9	negative selection	7468800
47564987	47565010	X	+	27260156	MEWO	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6351982415954199	[666]	[1191,874,883]	9	hSpCas9	negative selection	7468801
47565127	47565150	X	-	27260156	MEWO	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.08768537496366346	[307]	[185,361,346]	2	hSpCas9	negative selection	7533083
47566890	47566913	X	+	27260156	MEWO	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.23743278595189743	[531]	[545,636,568]	5	hSpCas9	negative selection	7533084
47566892	47566915	X	-	27260156	MEWO	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.2972558806831089	[723]	[585,609,463]	-6	hSpCas9	negative selection	7533085
47563306	47563329	X	+	27260156	LNCAPCLONEFGC	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.5243196174483702	[817]	[1164,847,1195,1084]	7	hSpCas9	negative selection	7590050
47563234	47563257	X	-	27260156	LNCAPCLONEFGC	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.5711636105027533	[1160]	[1526,1403,1870,1503]	8	hSpCas9	negative selection	7590051
47564987	47565010	X	+	27260156	LNCAPCLONEFGC	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6496320678417556	[666]	[923,1040,798,998]	8	hSpCas9	negative selection	7590052
47565127	47565150	X	-	27260156	LNCAPCLONEFGC	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.4052772899053978	[307]	[310,389,547,254]	6	hSpCas9	negative selection	7654334
47566890	47566913	X	+	27260156	LNCAPCLONEFGC	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.15061419410548155	[531]	[441,477,689,557]	2	hSpCas9	negative selection	7654335
47566892	47566915	X	-	27260156	LNCAPCLONEFGC	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.02631553577342438	[723]	[649,521,578,916]	0	hSpCas9	negative selection	7654336
47563306	47563329	X	+	27260156	PANC0327	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.4355158825261001	[817]	[1192,846,861,1062]	6	hSpCas9	negative selection	7711301
47563234	47563257	X	-	27260156	PANC0327	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.2841246055559796	[1160]	[1624,1079,1278,1091]	4	hSpCas9	negative selection	7711302
47564987	47565010	X	+	27260156	PANC0327	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6041606387649573	[666]	[1533,731,762,646]	8	hSpCas9	negative selection	7711303
47565127	47565150	X	-	27260156	PANC0327	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.19121878320467167	[307]	[360,375,202,304]	3	hSpCas9	negative selection	7775585
47566890	47566913	X	+	27260156	PANC0327	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	-0.1958184808058922	[531]	[303,420,318,595]	-3	hSpCas9	negative selection	7775586
47566892	47566915	X	-	27260156	PANC0327	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.09828724952274093	[723]	[501,513,637,751]	-1	hSpCas9	negative selection	7775587
47563306	47563329	X	+	27260156	NCIH2009	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.5949689087793262	[817]	[1762,1894,1521]	7	hSpCas9	negative selection	7832552
47563234	47563257	X	-	27260156	NCIH2009	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.31739278868717946	[1160]	[2702,1585,1913]	4	hSpCas9	negative selection	7832553
47564987	47565010	X	+	27260156	NCIH2009	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.7447655322517358	[666]	[1496,1360,1814]	8	hSpCas9	negative selection	7832554
47565127	47565150	X	-	27260156	NCIH2009	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.06775321615300378	[307]	[453,498,398]	0	hSpCas9	negative selection	7896836
47566890	47566913	X	+	27260156	NCIH2009	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.20394298381427084	[531]	[832,713,1017]	2	hSpCas9	negative selection	7896837
47566892	47566915	X	-	27260156	NCIH2009	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.010829068634214845	[723]	[1181,1136,723]	0	hSpCas9	negative selection	7896838
47563306	47563329	X	+	27260156	NCIH1373	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.7844849348337342	[817]	[1793,1326,1957,331]	7	hSpCas9	negative selection	7953803
47563234	47563257	X	-	27260156	NCIH1373	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.5915073488355103	[1160]	[3373,848,2162,465]	6	hSpCas9	negative selection	7953804
47564987	47565010	X	+	27260156	NCIH1373	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	1.0271780552915204	[666]	[1870,938,1948,375]	9	hSpCas9	negative selection	7953805
47565127	47565150	X	-	27260156	NCIH1373	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.38161444769085706	[307]	[332,178,239,86]	-4	hSpCas9	negative selection	8018087
47566890	47566913	X	+	27260156	NCIH1373	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.5653250105182297	[531]	[1018,767,1143,158]	5	hSpCas9	negative selection	8018088
47566892	47566915	X	-	27260156	NCIH1373	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.15614103084335873	[723]	[1042,796,815,261]	1	hSpCas9	negative selection	8018089
47563306	47563329	X	+	27260156	PATU8902	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.9811975621164659	[817]	[2222,2640,1685,2619]	9	hSpCas9	negative selection	8075054
47563234	47563257	X	-	27260156	PATU8902	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.7147933707476692	[1160]	[2225,2612,2309,3659]	7	hSpCas9	negative selection	8075055
47564987	47565010	X	+	27260156	PATU8902	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	1.0169098542381496	[666]	[1683,1691,1986,2146]	9	hSpCas9	negative selection	8075056
47565127	47565150	X	-	27260156	PATU8902	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.5969515637989617	[307]	[724,834,488,572]	6	hSpCas9	negative selection	8139338
47566890	47566913	X	+	27260156	PATU8902	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.5202650698316551	[531]	[1107,1157,914,1103]	5	hSpCas9	negative selection	8139339
47566892	47566915	X	-	27260156	PATU8902	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.6237487580858945	[723]	[1285,1578,1016,2586]	6	hSpCas9	negative selection	8139340
47563306	47563329	X	+	27260156	PANC1	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.4190843029542539	[817]	[880,1329,940,709]	6	hSpCas9	negative selection	8196305
47563234	47563257	X	-	27260156	PANC1	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.5253343777362827	[1160]	[1550,1806,1245,1220]	8	hSpCas9	negative selection	8196306
47564987	47565010	X	+	27260156	PANC1	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.5040418951228999	[666]	[673,1097,685,834]	7	hSpCas9	negative selection	8196307
47565127	47565150	X	-	27260156	PANC1	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.6447163214474428	[307]	[568,432,379,286]	9	hSpCas9	negative selection	8260589
47566890	47566913	X	+	27260156	PANC1	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.23139263430278995	[531]	[497,754,614,346]	3	hSpCas9	negative selection	8260590
47566892	47566915	X	-	27260156	PANC1	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	0.18391018312207774	[723]	[681,902,836,472]	3	hSpCas9	negative selection	8260591
47563306	47563329	X	+	27260156	PANC0813	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.44380266587880324	[817]	[1340,1219,1342,1323]	7	hSpCas9	negative selection	8317556
47563234	47563257	X	-	27260156	PANC0813	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.05996608693444494	[1160]	[1834,1238,1301,1349]	1	hSpCas9	negative selection	8317557
47564987	47565010	X	+	27260156	PANC0813	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6298540936847011	[666]	[1290,1257,1141,1165]	8	hSpCas9	negative selection	8317558
47565127	47565150	X	-	27260156	PANC0813	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.12481340723528245	[307]	[360,416,586,219]	2	hSpCas9	negative selection	8381840
47566890	47566913	X	+	27260156	PANC0813	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.41799806049906113	[531]	[789,1006,728,808]	6	hSpCas9	negative selection	8381841
47566892	47566915	X	-	27260156	PANC0813	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.24022562952627002	[723]	[913,691,792,509]	-4	hSpCas9	negative selection	8381842
47563306	47563329	X	+	27260156	RDES	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.174126390948789	[817]	[817,938,1269,1295]	3	hSpCas9	negative selection	8438807
47563234	47563257	X	-	27260156	RDES	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.3084074834205164	[1160]	[1313,1389,1896,2147]	5	hSpCas9	negative selection	8438808
47564987	47565010	X	+	27260156	RDES	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.735542500498991	[666]	[863,1334,1442,1564]	9	hSpCas9	negative selection	8438809
47565127	47565150	X	-	27260156	RDES	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.3346576546433115	[307]	[328,429,554,498]	5	hSpCas9	negative selection	8503091
47566890	47566913	X	+	27260156	RDES	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.2858790120452741	[531]	[557,724,855,891]	4	hSpCas9	negative selection	8503092
47566892	47566915	X	-	27260156	RDES	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.00892950387177105	[723]	[716,704,863,1072]	0	hSpCas9	negative selection	8503093
47563306	47563329	X	+	27260156	PC3	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.0008090270814986589	[817]	[511,684,1390,967]	0	hSpCas9	negative selection	8560058
47563234	47563257	X	-	27260156	PC3	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.2134630878142072	[1160]	[821,992,2570,1593]	5	hSpCas9	negative selection	8560059
47564987	47565010	X	+	27260156	PC3	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6934769706370022	[666]	[650,877,2391,986]	9	hSpCas9	negative selection	8560060
47565127	47565150	X	-	27260156	PC3	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.36288715110964	[307]	[246,355,709,418]	7	hSpCas9	negative selection	8624342
47566890	47566913	X	+	27260156	PC3	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.42518539001958705	[531]	[634,504,1002,771]	8	hSpCas9	negative selection	8624343
47566892	47566915	X	-	27260156	PC3	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.1791667590182956	[723]	[440,527,895,817]	-4	hSpCas9	negative selection	8624344
47563306	47563329	X	+	27260156	PATU8988T	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.46718822952342687	[817]	[1321,970,1100,953]	7	hSpCas9	negative selection	8681309
47563234	47563257	X	-	27260156	PATU8988T	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.05543753973280485	[1160]	[1076,1210,1140,1244]	1	hSpCas9	negative selection	8681310
47564987	47565010	X	+	27260156	PATU8988T	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.5628136048039708	[666]	[1225,837,907,814]	8	hSpCas9	negative selection	8681311
47565127	47565150	X	-	27260156	PATU8988T	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.1858876412347077	[307]	[286,288,532,228]	3	hSpCas9	negative selection	8745593
47566890	47566913	X	+	27260156	PATU8988T	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.6002049456469818	[531]	[495,623,1379,577]	8	hSpCas9	negative selection	8745594
47566892	47566915	X	-	27260156	PATU8988T	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.2104540186239635	[723]	[535,697,582,610]	-4	hSpCas9	negative selection	8745595
47563306	47563329	X	+	27260156	T47D	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.1546844621478347	[817]	[1083,997,957,1214]	3	hSpCas9	negative selection	8802560
47563234	47563257	X	-	27260156	T47D	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.19964974598382867	[1160]	[1570,1543,1598,1496]	4	hSpCas9	negative selection	8802561
47564987	47565010	X	+	27260156	T47D	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6806928902244057	[666]	[1227,1191,1240,1327]	9	hSpCas9	negative selection	8802562
47565127	47565150	X	-	27260156	T47D	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.14647214243541962	[307]	[408,416,370,389]	3	hSpCas9	negative selection	8866844
47566890	47566913	X	+	27260156	T47D	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.25752114557144307	[531]	[844,685,721,714]	5	hSpCas9	negative selection	8866845
47566892	47566915	X	-	27260156	T47D	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.15185901176091915	[723]	[750,709,834,742]	-3	hSpCas9	negative selection	8866846
47563306	47563329	X	+	27260156	SU8686	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.27688048744726146	[817]	[914,1040,934,1039]	5	hSpCas9	negative selection	8923811
47563234	47563257	X	-	27260156	SU8686	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.32541878735808627	[1160]	[1410,1371,1517,1477]	5	hSpCas9	negative selection	8923812
47564987	47565010	X	+	27260156	SU8686	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6627209125440753	[666]	[886,847,1217,1319]	9	hSpCas9	negative selection	8923813
47565127	47565150	X	-	27260156	SU8686	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.08857908773816459	[307]	[250,296,284,321]	-1	hSpCas9	negative selection	8988095
47566890	47566913	X	+	27260156	SU8686	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.22597664680996193	[531]	[598,586,562,737]	4	hSpCas9	negative selection	8988096
47566892	47566915	X	-	27260156	SU8686	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.017098603653883715	[723]	[612,651,683,937]	0	hSpCas9	negative selection	8988097
47563306	47563329	X	+	27260156	SKES1	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.18302677354988883	[817]	[842,1037,974,849]	4	hSpCas9	negative selection	9045062
47563234	47563257	X	-	27260156	SKES1	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.1477532103863275	[1160]	[1261,1317,1245,1292]	3	hSpCas9	negative selection	9045063
47564987	47565010	X	+	27260156	SKES1	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.4561122583045242	[666]	[918,1036,1041,684]	8	hSpCas9	negative selection	9045064
47565127	47565150	X	-	27260156	SKES1	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.19477989977174115	[307]	[562,381,259,244]	4	hSpCas9	negative selection	9109346
47566890	47566913	X	+	27260156	SKES1	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.40051920026153903	[531]	[602,816,743,637]	7	hSpCas9	negative selection	9109347
47566892	47566915	X	-	27260156	SKES1	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.0923167885271764	[723]	[760,784,532,652]	-2	hSpCas9	negative selection	9109348
47563306	47563329	X	+	27260156	TOV112D	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.15827937860581098	[817]	[979,1122,859,753]	3	hSpCas9	negative selection	9166313
47563234	47563257	X	-	27260156	TOV112D	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.21317139136970575	[1160]	[1373,1569,1283,1221]	4	hSpCas9	negative selection	9166314
47564987	47565010	X	+	27260156	TOV112D	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.878997248604548	[666]	[988,1799,1024,1218]	9	hSpCas9	negative selection	9166315
47565127	47565150	X	-	27260156	TOV112D	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.1568533118115631	[307]	[366,430,276,323]	3	hSpCas9	negative selection	9230597
47566890	47566913	X	+	27260156	TOV112D	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.21564624029983398	[531]	[585,1058,551,388]	4	hSpCas9	negative selection	9230598
47566892	47566915	X	-	27260156	TOV112D	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.172650474404001	[723]	[937,691,586,398]	-3	hSpCas9	negative selection	9230599
47563306	47563329	X	+	27260156	TC71	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.1327253842582834	[817]	[922,764,996,1172]	3	hSpCas9	negative selection	9287564
47563234	47563257	X	-	27260156	TC71	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.054316954750298185	[1160]	[1251,1267,1263,1392]	1	hSpCas9	negative selection	9287565
47564987	47565010	X	+	27260156	TC71	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.43764858954635366	[666]	[819,1008,1017,1031]	8	hSpCas9	negative selection	9287566
47565127	47565150	X	-	27260156	TC71	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	-0.12624057207474626	[307]	[336,310,235,328]	-3	hSpCas9	negative selection	9351848
47566890	47566913	X	+	27260156	TC71	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.27956041184812797	[531]	[711,694,600,767]	6	hSpCas9	negative selection	9351849
47566892	47566915	X	-	27260156	TC71	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.1852110883954382	[723]	[506,813,685,729]	-5	hSpCas9	negative selection	9351850
47563306	47563329	X	+	27260156	TC32	viability	TGTGGTCTACCGACTCATCAAGG	ARAF	ENSG00000078061	0.1396727315453452	[817]	[832,572,1057,1025]	2	hSpCas9	negative selection	9408815
47563234	47563257	X	-	27260156	TC32	viability	CGTAGACACTCATGCCATCCCGG	ARAF	ENSG00000078061	0.29610745376994063	[1160]	[1331,1053,1659,1397]	5	hSpCas9	negative selection	9408816
47564987	47565010	X	+	27260156	TC32	viability	ACGGAAGACCTTCTTCAGCCTGG	ARAF	ENSG00000078061	0.6477071858295583	[666]	[902,839,1126,1091]	9	hSpCas9	negative selection	9408817
47565127	47565150	X	-	27260156	TC32	viability	CTGGGCTCACTGTTGGCGGTTGG	ARAF	ENSG00000078061	0.3444496390915262	[307]	[345,338,397,382]	6	hSpCas9	negative selection	9473099
47566890	47566913	X	+	27260156	TC32	viability	GGCCAGAGTTTCAGCACTGATGG	ARAF	ENSG00000078061	0.23392548624662146	[531]	[534,476,738,642]	4	hSpCas9	negative selection	9473100
47566892	47566915	X	-	27260156	TC32	viability	CACCATCAGTGCTGAAACTCTGG	ARAF	ENSG00000078061	-0.09972911324919442	[723]	[615,485,801,687]	-2	hSpCas9	negative selection	9473101
47563039	47563062	X	-	27869803	HPAFII	viability after 27 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.2526033556859314	[253]	[127,184,NaN]	2	hSpCas9	negative selection	9608850
47563308	47563331	X	+	27869803	HPAFII	viability after 27 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.8387643167380355	[302]	[285,283,NaN]	6	hSpCas9	negative selection	9608851
47565061	47565084	X	-	27869803	HPAFII	viability after 27 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.7409326501864536	[211]	[152,213,NaN]	6	hSpCas9	negative selection	9608852
47565262	47565285	X	+	27869803	HPAFII	viability after 27 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.14588170756531793	[140]	[126,16,NaN]	-1	hSpCas9	negative selection	9608853
47566722	47566745	X	-	27869803	HPAFII	viability after 27 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.4485481010825015	[175]	[152,103,NaN]	3	hSpCas9	negative selection	9608854
47567321	47567344	X	+	27869803	HPAFII	viability after 27 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	1.4162210436945453	[98]	[157,122,NaN]	9	hSpCas9	negative selection	9608855
47563039	47563062	X	-	27869803	HPAFII	viability after 15 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.5918698648366505	[253]	[198,169,NaN]	-6	hSpCas9	negative selection	9691299
47563308	47563331	X	+	27869803	HPAFII	viability after 15 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.5870479153480429	[302]	[712,349,NaN]	6	hSpCas9	negative selection	9691300
47565061	47565084	X	-	27869803	HPAFII	viability after 15 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.931106424264716	[211]	[640,305,NaN]	8	hSpCas9	negative selection	9691301
47565262	47565285	X	+	27869803	HPAFII	viability after 15 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.16742380400297707	[140]	[348,58,NaN]	2	hSpCas9	negative selection	9691302
47566722	47566745	X	-	27869803	HPAFII	viability after 15 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.9224447361206911	[175]	[413,323,NaN]	8	hSpCas9	negative selection	9691303
47567321	47567344	X	+	27869803	HPAFII	viability after 15 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	0.8151166136893797	[98]	[201,177,NaN]	8	hSpCas9	negative selection	9691304
47563039	47563062	X	-	27869803	ASPC1	viability after 36 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.32818825631913473	[540]	[166,287,27]	-3	hSpCas9	negative selection	9773748
47563308	47563331	X	+	27869803	ASPC1	viability after 36 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.19843803758672718	[951]	[419,310,405]	2	hSpCas9	negative selection	9773749
47565061	47565084	X	-	27869803	ASPC1	viability after 36 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.9045577408573133	[473]	[406,270,268]	8	hSpCas9	negative selection	9773750
47565262	47565285	X	+	27869803	ASPC1	viability after 36 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.36567108657353686	[516]	[442,91,193]	3	hSpCas9	negative selection	9773751
47566722	47566745	X	-	27869803	ASPC1	viability after 36 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	-0.6978086811282826	[560]	[173,140,65]	-6	hSpCas9	negative selection	9773752
47567321	47567344	X	+	27869803	ASPC1	viability after 36 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	1.6162897672376215	[378]	[157,251,696]	9	hSpCas9	negative selection	9773753
47563039	47563062	X	-	27869803	PATU8988S	viability after 35 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.09532891470496754	[468]	[110,292,NaN]	1	hSpCas9	negative selection	9856197
47563308	47563331	X	+	27869803	PATU8988S	viability after 35 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	0.010723487414582067	[695]	[240,323,NaN]	0	hSpCas9	negative selection	9856198
47565061	47565084	X	-	27869803	PATU8988S	viability after 35 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	1.0958456847233888	[473]	[422,392,NaN]	9	hSpCas9	negative selection	9856199
47565262	47565285	X	+	27869803	PATU8988S	viability after 35 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.8675980066039197	[513]	[93,132,NaN]	-7	hSpCas9	negative selection	9856200
47566722	47566745	X	-	27869803	PATU8988S	viability after 35 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	-0.25980947976067864	[531]	[157,199,NaN]	-3	hSpCas9	negative selection	9856201
47567321	47567344	X	+	27869803	PATU8988S	viability after 35 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.1339257530875615	[232]	[94,75,NaN]	-1	hSpCas9	negative selection	9856202
47563039	47563062	X	-	27869803	PATU8988S	viability after 31 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.41148701950590477	[468]	[125,404,NaN]	5	hSpCas9	negative selection	9938646
47563308	47563331	X	+	27869803	PATU8988S	viability after 31 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	-0.14776380350186655	[695]	[191,324,NaN]	-2	hSpCas9	negative selection	9938647
47565061	47565084	X	-	27869803	PATU8988S	viability after 31 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	0.8715198933917891	[473]	[347,342,NaN]	8	hSpCas9	negative selection	9938648
47565262	47565285	X	+	27869803	PATU8988S	viability after 31 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.3404184489811842	[513]	[138,190,NaN]	-4	hSpCas9	negative selection	9938649
47566722	47566745	X	-	27869803	PATU8988S	viability after 31 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	-0.36636444002026286	[531]	[153,177,NaN]	-4	hSpCas9	negative selection	9938650
47567321	47567344	X	+	27869803	PATU8988S	viability after 31 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	-0.15791821269718076	[232]	[55,117,NaN]	-2	hSpCas9	negative selection	9938651
47563039	47563062	X	-	27869803	HPAFII	viability after 35 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	0.3480321935227066	[253]	[86,249,NaN]	2	hSpCas9	negative selection	10021095
47563308	47563331	X	+	27869803	HPAFII	viability after 35 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	1.1146752024486535	[302]	[191,489,NaN]	7	hSpCas9	negative selection	10021096
47565061	47565084	X	-	27869803	HPAFII	viability after 35 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	1.4992040245708376	[211]	[261,349,NaN]	8	hSpCas9	negative selection	10021097
47565262	47565285	X	+	27869803	HPAFII	viability after 35 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.21787197138276493	[140]	[106,9,NaN]	-1	hSpCas9	negative selection	10021098
47566722	47566745	X	-	27869803	HPAFII	viability after 35 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.6571035475049863	[175]	[84,202,NaN]	4	hSpCas9	negative selection	10021099
47567321	47567344	X	+	27869803	HPAFII	viability after 35 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	1.4364162150223037	[98]	[129,141,NaN]	8	hSpCas9	negative selection	10021100
47563039	47563062	X	-	27869803	HPAFII	viability after 31 days	CCGTGCGTTGCTTGTTGGGCAGG	ARAF	ENSG00000078061	-0.16687224522352104	[253]	[92,163,NaN]	-1	hSpCas9	negative selection	10103544
47563308	47563331	X	+	27869803	HPAFII	viability after 31 days	TGGTCTACCGACTCATCAAGGGG	ARAF	ENSG00000078061	1.3212737570947066	[302]	[266,596,NaN]	8	hSpCas9	negative selection	10103545
47565061	47565084	X	-	27869803	HPAFII	viability after 31 days	CTGGTGGAACTTGTAGCCACAGG	ARAF	ENSG00000078061	1.4814210475790655	[211]	[336,326,NaN]	9	hSpCas9	negative selection	10103546
47565262	47565285	X	+	27869803	HPAFII	viability after 31 days	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.0030517649649141054	[140]	[133,18,NaN]	0	hSpCas9	negative selection	10103547
47566722	47566745	X	-	27869803	HPAFII	viability after 31 days	GACCATATGGACGTTGGGAGTGG	ARAF	ENSG00000078061	0.9539019597807512	[175]	[142,243,NaN]	7	hSpCas9	negative selection	10103548
47567321	47567344	X	+	27869803	HPAFII	viability after 31 days	GCACCGTGTTTCGAGGGCGGTGG	ARAF	ENSG00000078061	1.156714231976359	[98]	[120,126,NaN]	8	hSpCas9	negative selection	10103549
47563007	47563030	X	-	28162770	P31FUJ	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.0791418019003618	[405]	[503]	0	hSpCas9	negative selection	10112575
47565091	47565114	X	-	28162770	P31FUJ	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.09184027517001958	[530]	[664]	0	hSpCas9	negative selection	10112576
47563042	47563065	X	+	28162770	P31FUJ	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	1.2313621523356406	[82]	[228]	9	hSpCas9	negative selection	10112577
47565041	47565064	X	-	28162770	P31FUJ	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.5041633897518274	[95]	[159]	6	hSpCas9	negative selection	10112578
47565262	47565285	X	+	28162770	P31FUJ	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.2311448953454116	[28]	[39]	2	hSpCas9	negative selection	10112579
47562960	47562983	X	+	28162770	P31FUJ	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.654344455895725	[205]	[380]	7	hSpCas9	negative selection	10112580
47562988	47563011	X	-	28162770	P31FUJ	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	1.0819838212289639	[323]	[805]	9	hSpCas9	negative selection	10112581
47565316	47565339	X	-	28162770	P31FUJ	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	-0.5640081128897521	[38]	[30]	-5	hSpCas9	negative selection	10112582
47563263	47563286	X	+	28162770	P31FUJ	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	1.0561939952833703	[256]	[627]	9	hSpCas9	negative selection	10112583
47563307	47563330	X	+	28162770	P31FUJ	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.7482562319321611	[459]	[907]	8	hSpCas9	negative selection	10112584
47563007	47563030	X	-	28162770	TF1	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	NaN	[NaN]	[484]	1	hSpCas9	negative selection	10281941
47565091	47565114	X	-	28162770	TF1	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	NaN	[NaN]	[441]	1	hSpCas9	negative selection	10281942
47563042	47563065	X	+	28162770	TF1	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10281943
47565041	47565064	X	-	28162770	TF1	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10281944
47565262	47565285	X	+	28162770	TF1	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10281945
47562960	47562983	X	+	28162770	TF1	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10281946
47562988	47563011	X	-	28162770	TF1	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	NaN	[NaN]	[313]	1	hSpCas9	negative selection	10281947
47565316	47565339	X	-	28162770	TF1	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10281948
47563263	47563286	X	+	28162770	TF1	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	NaN	[NaN]	[506]	1	hSpCas9	negative selection	10281949
47563307	47563330	X	+	28162770	TF1	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	NaN	[NaN]	[516]	1	hSpCas9	negative selection	10281950
47563007	47563030	X	-	28162770	SKM1	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	1.4027045891526893	[88]	[415]	9	hSpCas9	negative selection	10451307
47565091	47565114	X	-	28162770	SKM1	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	1.0818801477141746	[127]	[478]	8	hSpCas9	negative selection	10451308
47563042	47563065	X	+	28162770	SKM1	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	1.7085130186767743	[17]	[103]	9	hSpCas9	negative selection	10451309
47565041	47565064	X	-	28162770	SKM1	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	1.9237341057719326	[40]	[274]	9	hSpCas9	negative selection	10451310
47565262	47565285	X	+	28162770	SKM1	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.12553088208385876	[13]	[26]	1	hSpCas9	negative selection	10451311
47562960	47562983	X	+	28162770	SKM1	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	1.7531130167428033	[48]	[291]	9	hSpCas9	negative selection	10451312
47562988	47563011	X	-	28162770	SKM1	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.7753979059373732	[76]	[232]	7	hSpCas9	negative selection	10451313
47565316	47565339	X	-	28162770	SKM1	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	-0.05646695165902882	[9]	[16]	0	hSpCas9	negative selection	10451314
47563263	47563286	X	+	28162770	SKM1	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	1.5690189201383027	[52]	[277]	9	hSpCas9	negative selection	10451315
47563307	47563330	X	+	28162770	SKM1	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.6804986425071777	[113]	[322]	6	hSpCas9	negative selection	10451316
47563007	47563030	X	-	28162770	SKM1	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	1.4027045891526893	[88]	[415]	9	hSpCas9	negative selection	10620673
47565091	47565114	X	-	28162770	SKM1	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	1.0818801477141746	[127]	[478]	8	hSpCas9	negative selection	10620674
47563042	47563065	X	+	28162770	SKM1	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	1.7085130186767743	[17]	[103]	9	hSpCas9	negative selection	10620675
47565041	47565064	X	-	28162770	SKM1	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	1.9237341057719326	[40]	[274]	9	hSpCas9	negative selection	10620676
47565262	47565285	X	+	28162770	SKM1	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.12553088208385876	[13]	[26]	1	hSpCas9	negative selection	10620677
47562960	47562983	X	+	28162770	SKM1	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	1.7531130167428033	[48]	[291]	9	hSpCas9	negative selection	10620678
47562988	47563011	X	-	28162770	SKM1	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.7753979059373732	[76]	[232]	7	hSpCas9	negative selection	10620679
47565316	47565339	X	-	28162770	SKM1	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	-0.05646695165902882	[9]	[16]	0	hSpCas9	negative selection	10620680
47563263	47563286	X	+	28162770	SKM1	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	1.5690189201383027	[52]	[277]	9	hSpCas9	negative selection	10620681
47563307	47563330	X	+	28162770	SKM1	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.6804986425071777	[113]	[322]	6	hSpCas9	negative selection	10620682
47563007	47563030	X	-	28162770	PL21	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.36332978190290466	[333]	[186]	3	hSpCas9	negative selection	10790039
47565091	47565114	X	-	28162770	PL21	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	1.32670357577299	[348]	[380]	9	hSpCas9	negative selection	10790040
47563042	47563065	X	+	28162770	PL21	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	-1.697100811085479	[148]	[19]	-8	hSpCas9	negative selection	10790041
47565041	47565064	X	-	28162770	PL21	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.5461354693385128	[106]	[67]	5	hSpCas9	negative selection	10790042
47565262	47565285	X	+	28162770	PL21	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-1.1217884803980422	[39]	[7]	-6	hSpCas9	negative selection	10790043
47562960	47562983	X	+	28162770	PL21	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	-0.16360865609266925	[174]	[67]	-1	hSpCas9	negative selection	10790044
47562988	47563011	X	-	28162770	PL21	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	-0.3206925488121203	[263]	[91]	-2	hSpCas9	negative selection	10790045
47565316	47565339	X	-	28162770	PL21	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	0.20013961448932038	[29]	[14]	1	hSpCas9	negative selection	10790046
47563263	47563286	X	+	28162770	PL21	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.4125479472531459	[144]	[83]	3	hSpCas9	negative selection	10790047
47563307	47563330	X	+	28162770	PL21	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.618909832644494	[385]	[257]	5	hSpCas9	negative selection	10790048
47563007	47563030	X	-	28162770	P31FUJ	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.0791418019003618	[405]	[503]	0	hSpCas9	negative selection	10959405
47565091	47565114	X	-	28162770	P31FUJ	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.09184027517001958	[530]	[664]	0	hSpCas9	negative selection	10959406
47563042	47563065	X	+	28162770	P31FUJ	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	1.2313621523356406	[82]	[228]	9	hSpCas9	negative selection	10959407
47565041	47565064	X	-	28162770	P31FUJ	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.5041633897518274	[95]	[159]	6	hSpCas9	negative selection	10959408
47565262	47565285	X	+	28162770	P31FUJ	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.2311448953454116	[28]	[39]	2	hSpCas9	negative selection	10959409
47562960	47562983	X	+	28162770	P31FUJ	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.654344455895725	[205]	[380]	7	hSpCas9	negative selection	10959410
47562988	47563011	X	-	28162770	P31FUJ	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	1.0819838212289639	[323]	[805]	9	hSpCas9	negative selection	10959411
47565316	47565339	X	-	28162770	P31FUJ	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	-0.5640081128897521	[38]	[30]	-5	hSpCas9	negative selection	10959412
47563263	47563286	X	+	28162770	P31FUJ	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	1.0561939952833703	[256]	[627]	9	hSpCas9	negative selection	10959413
47563307	47563330	X	+	28162770	P31FUJ	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.7482562319321611	[459]	[907]	8	hSpCas9	negative selection	10959414
47563007	47563030	X	-	28162770	OCIAML5	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.38894152863979786	[153]	[363]	3	hSpCas9	negative selection	11128771
47565091	47565114	X	-	28162770	OCIAML5	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	-0.29667718552618805	[344]	[506]	-2	hSpCas9	negative selection	11128772
47563042	47563065	X	+	28162770	OCIAML5	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.5219082717929605	[48]	[126]	4	hSpCas9	negative selection	11128773
47565041	47565064	X	-	28162770	OCIAML5	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	2.712718047919529	[23]	[283]	9	hSpCas9	negative selection	11128774
47565262	47565285	X	+	28162770	OCIAML5	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-1.5219179691716662	[34]	[21]	-7	hSpCas9	negative selection	11128775
47562960	47562983	X	+	28162770	OCIAML5	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	1.348752438524099	[76]	[353]	9	hSpCas9	negative selection	11128776
47562988	47563011	X	-	28162770	OCIAML5	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	1.2005480552994248	[174]	[725]	8	hSpCas9	negative selection	11128777
47565316	47565339	X	-	28162770	OCIAML5	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	1.1874617933226406	[26]	[110]	8	hSpCas9	negative selection	11128778
47563263	47563286	X	+	28162770	OCIAML5	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.11798020703437523	[145]	[285]	1	hSpCas9	negative selection	11128779
47563307	47563330	X	+	28162770	OCIAML5	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.9848636873531293	[268]	[960]	8	hSpCas9	negative selection	11128780
47563007	47563030	X	-	28162770	EOL1	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.2543000829044091	[661]	[415]	2	hSpCas9	negative selection	11298137
47565091	47565114	X	-	28162770	EOL1	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.04788710676344099	[548]	[298]	0	hSpCas9	negative selection	11298138
47563042	47563065	X	+	28162770	EOL1	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.021055752423881025	[158]	[84]	0	hSpCas9	negative selection	11298139
47565041	47565064	X	-	28162770	EOL1	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	-0.15972114532706927	[281]	[132]	-1	hSpCas9	negative selection	11298140
47565262	47565285	X	+	28162770	EOL1	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.0726464105596687	[73]	[40]	0	hSpCas9	negative selection	11298141
47562960	47562983	X	+	28162770	EOL1	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.0908705363326513	[400]	[224]	0	hSpCas9	negative selection	11298142
47562988	47563011	X	-	28162770	EOL1	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.3239884157983598	[278]	[183]	3	hSpCas9	negative selection	11298143
47565316	47565339	X	-	28162770	EOL1	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	1.7416837144207242	[41]	[73]	9	hSpCas9	negative selection	11298144
47563263	47563286	X	+	28162770	EOL1	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.8336392753723243	[261]	[245]	7	hSpCas9	negative selection	11298145
47563307	47563330	X	+	28162770	EOL1	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.22771830287857586	[448]	[276]	2	hSpCas9	negative selection	11298146
47563007	47563030	X	-	28162770	MOLM13	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	1.588618845523364	[463]	[1008]	9	hSpCas9	negative selection	11467503
47565091	47565114	X	-	28162770	MOLM13	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	-0.11232740752592729	[606]	[405]	0	hSpCas9	negative selection	11467504
47563042	47563065	X	+	28162770	MOLM13	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	1.818605899856566	[128]	[328]	9	hSpCas9	negative selection	11467505
47565041	47565064	X	-	28162770	MOLM13	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	1.4455215685161242	[194]	[383]	9	hSpCas9	negative selection	11467506
47565262	47565285	X	+	28162770	MOLM13	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.48806726348220875	[70]	[71]	3	hSpCas9	negative selection	11467507
47562960	47562983	X	+	28162770	MOLM13	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	1.111008687822792	[234]	[366]	8	hSpCas9	negative selection	11467508
47562988	47563011	X	-	28162770	MOLM13	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.38114388266795896	[376]	[354]	2	hSpCas9	negative selection	11467509
47565316	47565339	X	-	28162770	MOLM13	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	1.4368624859239543	[46]	[91]	9	hSpCas9	negative selection	11467510
47563263	47563286	X	+	28162770	MOLM13	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	-0.49504852423387624	[268]	[137]	-3	hSpCas9	negative selection	11467511
47563307	47563330	X	+	28162770	MOLM13	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.1550380417763786	[712]	[573]	1	hSpCas9	negative selection	11467512
47563007	47563030	X	-	28162770	HEL	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	1.0560412799084533	[415]	[553]	8	hSpCas9	negative selection	11636869
47565091	47565114	X	-	28162770	HEL	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.5593942355212301	[480]	[453]	5	hSpCas9	negative selection	11636870
47563042	47563065	X	+	28162770	HEL	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.7076942738411268	[151]	[158]	6	hSpCas9	negative selection	11636871
47565041	47565064	X	-	28162770	HEL	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.6276319396101486	[191]	[189]	5	hSpCas9	negative selection	11636872
47565262	47565285	X	+	28162770	HEL	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.9875673289977982	[49]	[126]	9	hSpCas9	negative selection	11636873
47562960	47562983	X	+	28162770	HEL	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.5504803241483683	[225]	[211]	4	hSpCas9	negative selection	11636874
47562988	47563011	X	-	28162770	HEL	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.3123491583647986	[341]	[271]	2	hSpCas9	negative selection	11636875
47565316	47565339	X	-	28162770	HEL	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	1.0274026822356819	[35]	[46]	8	hSpCas9	negative selection	11636876
47563263	47563286	X	+	28162770	HEL	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	-0.6279958325150191	[262]	[108]	-4	hSpCas9	negative selection	11636877
47563307	47563330	X	+	28162770	HEL	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.1294505294121736	[480]	[336]	1	hSpCas9	negative selection	11636878
47563007	47563030	X	-	28162770	MV411	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	1.089372704550524	[317]	[569]	8	hSpCas9	negative selection	11806235
47565091	47565114	X	-	28162770	MV411	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.4626289452542627	[372]	[432]	4	hSpCas9	negative selection	11806236
47563042	47563065	X	+	28162770	MV411	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.43065937483854555	[95]	[108]	4	hSpCas9	negative selection	11806237
47565041	47565064	X	-	28162770	MV411	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.41473229618041596	[121]	[136]	3	hSpCas9	negative selection	11806238
47565262	47565285	X	+	28162770	MV411	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	0.09857416486829251	[50]	[45]	0	hSpCas9	negative selection	11806239
47562960	47562983	X	+	28162770	MV411	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	1.6762808495866497	[168]	[454]	9	hSpCas9	negative selection	11806240
47562988	47563011	X	-	28162770	MV411	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	1.4427851491049948	[199]	[457]	9	hSpCas9	negative selection	11806241
47565316	47565339	X	-	28162770	MV411	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	2.4869034854781646	[17]	[84]	9	hSpCas9	negative selection	11806242
47563263	47563286	X	+	28162770	MV411	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.45145144280436844	[157]	[181]	4	hSpCas9	negative selection	11806243
47563307	47563330	X	+	28162770	MV411	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.8090675476733078	[373]	[551]	7	hSpCas9	negative selection	11806244
47563007	47563030	X	-	28162770	MONOMAC1	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.04446439722459883	[224]	[265]	0	hSpCas9	negative selection	11975601
47565091	47565114	X	-	28162770	MONOMAC1	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.6808925655722271	[264]	[486]	6	hSpCas9	negative selection	11975602
47563042	47563065	X	+	28162770	MONOMAC1	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.1814747761941763	[69]	[90]	1	hSpCas9	negative selection	11975603
47565041	47565064	X	-	28162770	MONOMAC1	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	-0.5662706567252729	[92]	[71]	-5	hSpCas9	negative selection	11975604
47565262	47565285	X	+	28162770	MONOMAC1	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	1.1041326876610111	[27]	[68]	8	hSpCas9	negative selection	11975605
47562960	47562983	X	+	28162770	MONOMAC1	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	-0.0285311227025756	[112]	[126]	0	hSpCas9	negative selection	11975606
47562988	47563011	X	-	28162770	MONOMAC1	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	1.080121377707786	[143]	[348]	8	hSpCas9	negative selection	11975607
47565316	47565339	X	-	28162770	MONOMAC1	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	0.07859759555387358	[18]	[22]	0	hSpCas9	negative selection	11975608
47563263	47563286	X	+	28162770	MONOMAC1	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.8796889435832748	[118]	[250]	7	hSpCas9	negative selection	11975609
47563307	47563330	X	+	28162770	MONOMAC1	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	-0.016916078511352906	[187]	[212]	0	hSpCas9	negative selection	11975610
47563007	47563030	X	-	28162770	OCIAML2	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	0.3326381392922	[100]	[704]	3	hSpCas9	negative selection	12144967
47565091	47565114	X	-	28162770	OCIAML2	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	0.8163345973903706	[70]	[692]	7	hSpCas9	negative selection	12144968
47563042	47563065	X	+	28162770	OCIAML2	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	0.45536959331406207	[29]	[227]	4	hSpCas9	negative selection	12144969
47565041	47565064	X	-	28162770	OCIAML2	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	0.4436403007319547	[25]	[195]	4	hSpCas9	negative selection	12144970
47565262	47565285	X	+	28162770	OCIAML2	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-0.39262731324088795	[8]	[37]	-3	hSpCas9	negative selection	12144971
47562960	47562983	X	+	28162770	OCIAML2	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.06702696070063839	[30]	[179]	0	hSpCas9	negative selection	12144972
47562988	47563011	X	-	28162770	OCIAML2	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	1.9508339431961157	[27]	[599]	9	hSpCas9	negative selection	12144973
47565316	47565339	X	-	28162770	OCIAML2	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	-0.03767041796605497	[4]	[26]	0	hSpCas9	negative selection	12144974
47563263	47563286	X	+	28162770	OCIAML2	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	1.977351772651598	[22]	[501]	9	hSpCas9	negative selection	12144975
47563307	47563330	X	+	28162770	OCIAML2	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.9133362281036767	[65]	[688]	8	hSpCas9	negative selection	12144976
47563007	47563030	X	-	28162770	OCIAML3	viability	ACGGTGCCCACTGCCCGGGATGG	ARAF	ENSG00000078061	-0.018322953191017732	[103]	[309]	0	hSpCas9	negative selection	12314333
47565091	47565114	X	-	28162770	OCIAML3	viability	ACAGACTGTGGGGACCTTGGAGG	ARAF	ENSG00000078061	-0.0007775236194065283	[115]	[349]	0	hSpCas9	negative selection	12314334
47563042	47563065	X	+	28162770	OCIAML3	viability	GCCCAACAAGCAACGCACGGTGG	ARAF	ENSG00000078061	-0.28366751971201265	[24]	[61]	-2	hSpCas9	negative selection	12314335
47565041	47565064	X	-	28162770	OCIAML3	viability	AGGTTTGGCAACGGAAGCCATGG	ARAF	ENSG00000078061	1.0284295658156557	[37]	[233]	8	hSpCas9	negative selection	12314336
47565262	47565285	X	+	28162770	OCIAML3	viability	AGTGTCCAGGATTTGTCCGGAGG	ARAF	ENSG00000078061	-1.2403706857094627	[17]	[22]	-7	hSpCas9	negative selection	12314337
47562960	47562983	X	+	28162770	OCIAML3	viability	AAGGCTCCATGGAGCCACCACGG	ARAF	ENSG00000078061	0.6301604059021364	[57]	[270]	6	hSpCas9	negative selection	12314338
47562988	47563011	X	-	28162770	OCIAML3	viability	ATGGCTCGGCCCCATTGGCAGGG	ARAF	ENSG00000078061	0.26056192015427304	[72]	[263]	2	hSpCas9	negative selection	12314339
47565316	47565339	X	-	28162770	OCIAML3	viability	GGGGTTAGCAACTCATTCAGGGG	ARAF	ENSG00000078061	-2.4013625623817676	[6]	[3]	-9	hSpCas9	negative selection	12314340
47563263	47563286	X	+	28162770	OCIAML3	viability	TAGACAAGGCCCTGAAGGTGCGG	ARAF	ENSG00000078061	0.4752550221129507	[60]	[255]	4	hSpCas9	negative selection	12314341
47563307	47563330	X	+	28162770	OCIAML3	viability	GTGGTCTACCGACTCATCAAGGG	ARAF	ENSG00000078061	0.4442623766035543	[92]	[381]	4	hSpCas9	negative selection	12314342